C5a- and ASP-mediated C5L2 activation, endocytosis and recycling are lost in S323I-C5L2 mutation

Molecular Immunology

Volumn 46, Issue 15, 2009, Pages 3086-3098

  Cui, Wei ^a,c   Simaan, May ^c   Laporte, Stephane ^c   Lodge, Robert ^b   Cianflone, Katherine ^a,c  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Arrestin 2; C3adesArg; C5L2; G protein coupled receptor; Rab proteins

Indexed keywords

ACYLATION STIMULATING PROTEIN; BETA ARRESTIN 2; COMPLEMENT COMPONENT C5A; G PROTEIN COUPLED RECEPTOR; MUTANT PROTEIN; PROTEIN C5L2; RAB PROTEIN; RAB11 PROTEIN; RAB5 PROTEIN; RAB7 PROTEIN; RECOMBINANT PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; CYTOSOL; ENDOCYTOSIS; ENDOSOME; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR TRANSPORT; LYSOSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; STABLE TRANSFECTION; TRANSIENT TRANSFECTION;

ACYLATION; ARRESTINS; CELL LINE; COMPLEMENT C3A; COMPLEMENT C5A; ENDOCYTOSIS; HUMANS; MUTATION; PHOSPHORYLATION; RAB GTP-BINDING PROTEINS; RECEPTORS, CHEMOKINE; RECOMBINANT PROTEINS; SERINE; TRANSFECTION;

EID: 68749085769     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.06.007     Document Type: Article

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