메뉴 건너뛰기




Volumn 43, Issue 7, 2013, Pages 1907-1913

The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation

Author keywords

Akt; Cecal ligation and puncture; Macrophages; MEK1 2; Sepsis

Indexed keywords

COMPLEMENT COMPONENT C5; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT COMPONENT C5L2; GRANULOCYTE COLONY STIMULATING FACTOR; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 84880028085     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201243075     Document Type: Article
Times cited : (37)

References (32)
  • 1
    • 80555154767 scopus 로고    scopus 로고
    • Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis
    • Bosmann, M. and Ward, P. A., Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis. Adv. Exp. Med. Biol. 2012. 946: 147-159.
    • (2012) Adv. Exp. Med. Biol. , vol.946 , pp. 147-159
    • Bosmann, M.1    Ward, P.A.2
  • 2
    • 0028201342 scopus 로고
    • C5A anaphylatoxin and its seven transmembrane-segment receptor
    • Gerard, C. and Gerard, N. P., C5A anaphylatoxin and its seven transmembrane-segment receptor. Annu. Rev. Immunol. 1994. 12: 775-808.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 775-808
    • Gerard, C.1    Gerard, N.P.2
  • 3
    • 0026078539 scopus 로고
    • The chemotactic receptor for human C5a anaphylatoxin
    • Gerard, N. P. and Gerard, C., The chemotactic receptor for human C5a anaphylatoxin. Nature 1991. 349: 614-617.
    • (1991) Nature , vol.349 , pp. 614-617
    • Gerard, N.P.1    Gerard, C.2
  • 4
    • 0028930272 scopus 로고
    • Expression of the complement C5a anaphylatoxin receptor (C5aR) on non-myeloid cells
    • Wetsel, R. A., Expression of the complement C5a anaphylatoxin receptor (C5aR) on non-myeloid cells. Immunol. Lett. 1995. 44: 183-187.
    • (1995) Immunol. Lett. , vol.44 , pp. 183-187
    • Wetsel, R.A.1
  • 5
    • 84861137551 scopus 로고    scopus 로고
    • Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages
    • Bosmann, M., Haggadone, M. D., Hemmila, M. R., Zetoune, F. S., Sarma, J. V. and Ward, P. A., Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages. J. Immunol. 2012. 188: 5086-5093.
    • (2012) J. Immunol. , vol.188 , pp. 5086-5093
    • Bosmann, M.1    Haggadone, M.D.2    Hemmila, M.R.3    Zetoune, F.S.4    Sarma, J.V.5    Ward, P.A.6
  • 6
    • 52649176344 scopus 로고    scopus 로고
    • Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis
    • Lalli, P. N., Strainic, M. G., Yang, M., Lin, F., Medof, M. E. and Heeger, P. S., Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis. Blood 2008. 112: 1759-1766.
    • (2008) Blood , vol.112 , pp. 1759-1766
    • Lalli, P.N.1    Strainic, M.G.2    Yang, M.3    Lin, F.4    Medof, M.E.5    Heeger, P.S.6
  • 7
    • 77955883153 scopus 로고    scopus 로고
    • Complement: a key system for immune surveillance and homeostasis
    • Ricklin, D., Hajishengallis, G., Yang, K. and Lambris, J. D., Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 2010. 11: 785-797.
    • (2010) Nat. Immunol. , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 9
    • 0036510770 scopus 로고    scopus 로고
    • The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)
    • Cain, S. A. and Monk, P. N., The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74). J. Biol. Chem. 2002. 277: 7165-7169.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7165-7169
    • Cain, S.A.1    Monk, P.N.2
  • 11
    • 19944428475 scopus 로고    scopus 로고
    • Changes in the novel orphan, C5a receptor (C5L2), during experimental sepsis and sepsis in humans
    • Huber-Lang, M., Sarma, J. V., Rittirsch, D., Schreiber, H., Weiss, M., Flierl, M., Younkin, E. et al., Changes in the novel orphan, C5a receptor (C5L2), during experimental sepsis and sepsis in humans. J. Immunol. 2005. 174: 1104-1110.
    • (2005) J. Immunol. , vol.174 , pp. 1104-1110
    • Huber-Lang, M.1    Sarma, J.V.2    Rittirsch, D.3    Schreiber, H.4    Weiss, M.5    Flierl, M.6    Younkin, E.7
  • 13
    • 79959263956 scopus 로고    scopus 로고
    • Relationship between a novel polymorphism of the C5L2 gene and coronary artery disease
    • Zheng, Y. Y., Xie, X., Ma, Y. T., Yang, Y. N., Fu, Z. Y., Li, X. M., Ma, X. et al., Relationship between a novel polymorphism of the C5L2 gene and coronary artery disease. PLoS One 2011. 6: e20984.
    • (2011) PLoS One , vol.6
    • Zheng, Y.Y.1    Xie, X.2    Ma, Y.T.3    Yang, Y.N.4    Fu, Z.Y.5    Li, X.M.6    Ma, X.7
  • 14
    • 82655173731 scopus 로고    scopus 로고
    • MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway
    • Bosmann, M., Patel, V. R., Russkamp, N. F., Pache, F., Zetoune, F. S., Sarma, J. V. and Ward, P. A., MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway. FASEB J. 2011. 25: 4222-4232.
    • (2011) FASEB J. , vol.25 , pp. 4222-4232
    • Bosmann, M.1    Patel, V.R.2    Russkamp, N.F.3    Pache, F.4    Zetoune, F.S.5    Sarma, J.V.6    Ward, P.A.7
  • 15
    • 84860902599 scopus 로고    scopus 로고
    • Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis
    • Bosmann, M., Sarma, J. V., Atefi, G., Zetoune, F. S. and Ward, P. A., Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis. FASEB J. 2012. 26: 1640-1651.
    • (2012) FASEB J. , vol.26 , pp. 1640-1651
    • Bosmann, M.1    Sarma, J.V.2    Atefi, G.3    Zetoune, F.S.4    Ward, P.A.5
  • 16
    • 17444403917 scopus 로고    scopus 로고
    • C5a negatively regulates toll-like receptor 4-induced immune responses
    • Hawlisch, H., Belkaid, Y., Baelder, R., Hildeman, D., Gerard, C. and Kohl, J., C5a negatively regulates toll-like receptor 4-induced immune responses. Immunity 2005. 22: 415-426.
    • (2005) Immunity , vol.22 , pp. 415-426
    • Hawlisch, H.1    Belkaid, Y.2    Baelder, R.3    Hildeman, D.4    Gerard, C.5    Kohl, J.6
  • 17
    • 0033152662 scopus 로고    scopus 로고
    • C5a suppresses the production of IL-12 by IFN-gamma-primed and lipopolysaccharide-challenged human monocytes
    • Wittmann, M., Zwirner, J., Larsson, V. A., Kirchhoff, K., Begemann, G., Kapp, A., Gotze, O. et al., C5a suppresses the production of IL-12 by IFN-gamma-primed and lipopolysaccharide-challenged human monocytes. J. Immunol. 1999. 162: 6763-6769.
    • (1999) J. Immunol. , vol.162 , pp. 6763-6769
    • Wittmann, M.1    Zwirner, J.2    Larsson, V.A.3    Kirchhoff, K.4    Begemann, G.5    Kapp, A.6    Gotze, O.7
  • 20
    • 1442290129 scopus 로고    scopus 로고
    • Regulatory role of C5a in LPS-induced IL-6 production by neutrophils during sepsis
    • Riedemann, N. C., Guo, R. F., Hollmann, T. J., Gao, H., Neff, T. A., Reuben, J. S., Speyer, C. L. et al., Regulatory role of C5a in LPS-induced IL-6 production by neutrophils during sepsis. FASEB J. 2004. 18: 370-372.
    • (2004) FASEB J. , vol.18 , pp. 370-372
    • Riedemann, N.C.1    Guo, R.F.2    Hollmann, T.J.3    Gao, H.4    Neff, T.A.5    Reuben, J.S.6    Speyer, C.L.7
  • 21
    • 84860894209 scopus 로고    scopus 로고
    • Anti-inflammatory effects of beta2 adrenergic receptor agonists in experimental acute lung injury
    • Bosmann, M., Grailer, J. J., Zhu, K., Matthay, M. A., Sarma, J. V., Zetoune, F. S. and Ward, P. A., Anti-inflammatory effects of beta2 adrenergic receptor agonists in experimental acute lung injury. FASEB J. 2012. 26: 2137-2144.
    • (2012) FASEB J. , vol.26 , pp. 2137-2144
    • Bosmann, M.1    Grailer, J.J.2    Zhu, K.3    Matthay, M.A.4    Sarma, J.V.5    Zetoune, F.S.6    Ward, P.A.7
  • 22
    • 33947110020 scopus 로고    scopus 로고
    • C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a
    • Chen, N. J., Mirtsos, C., Suh, D., Lu, Y. C., Lin, W. J., McKerlie, C., Lee, T. et al., C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a. Nature 2007. 446: 203-207.
    • (2007) Nature , vol.446 , pp. 203-207
    • Chen, N.J.1    Mirtsos, C.2    Suh, D.3    Lu, Y.C.4    Lin, W.J.5    McKerlie, C.6    Lee, T.7
  • 23
    • 40249116606 scopus 로고    scopus 로고
    • Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells
    • Strainic, M. G., Liu, J., Huang, D., An, F., Lalli, P. N., Muqim, N., Shapiro, V. S. et al., Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. Immunity 2008. 28: 425-435.
    • (2008) Immunity , vol.28 , pp. 425-435
    • Strainic, M.G.1    Liu, J.2    Huang, D.3    An, F.4    Lalli, P.N.5    Muqim, N.6    Shapiro, V.S.7
  • 24
    • 77956955243 scopus 로고    scopus 로고
    • Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
    • Lajoie, S., Lewkowich, I. P., Suzuki, Y., Clark, J. R., Sproles, A. A., Dienger, K., Budelsky, A. L. et al., Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nat. Immunol. 2010. 11: 928-935.
    • (2010) Nat. Immunol. , vol.11 , pp. 928-935
    • Lajoie, S.1    Lewkowich, I.P.2    Suzuki, Y.3    Clark, J.R.4    Sproles, A.A.5    Dienger, K.6    Budelsky, A.L.7
  • 25
    • 34347400796 scopus 로고    scopus 로고
    • Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo
    • Zhang, X., Kimura, Y., Fang, C., Zhou, L., Sfyroera, G., Lambris, J. D., Wetsel, R. A. et al., Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo. Blood 2007. 110: 228-236.
    • (2007) Blood , vol.110 , pp. 228-236
    • Zhang, X.1    Kimura, Y.2    Fang, C.3    Zhou, L.4    Sfyroera, G.5    Lambris, J.D.6    Wetsel, R.A.7
  • 27
    • 70450284427 scopus 로고    scopus 로고
    • Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes
    • Lee, H. M., Wu, W., Wysoczynski, M., Liu, R., Zuba-Surma, E. K., Kucia, M., Ratajczak, J. et al., Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes. Leukemia 2009. 23: 2052-2062.
    • (2009) Leukemia , vol.23 , pp. 2052-2062
    • Lee, H.M.1    Wu, W.2    Wysoczynski, M.3    Liu, R.4    Zuba-Surma, E.K.5    Kucia, M.6    Ratajczak, J.7
  • 28
    • 77950845392 scopus 로고    scopus 로고
    • Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells
    • Jalili, A., Shirvaikar, N., Marquez-Curtis, L., Qiu, Y., Korol, C., Lee, H., Turner, A. R. et al., Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells. Exp. Hematol. 2010. 38: 321-332.
    • (2010) Exp. Hematol. , vol.38 , pp. 321-332
    • Jalili, A.1    Shirvaikar, N.2    Marquez-Curtis, L.3    Qiu, Y.4    Korol, C.5    Lee, H.6    Turner, A.R.7
  • 30
    • 0029795542 scopus 로고    scopus 로고
    • The C5a chemoattractant receptor mediates mucosal defence to infection
    • Hopken, U. E., Lu, B., Gerard, N. P. and Gerard, C., The C5a chemoattractant receptor mediates mucosal defence to infection. Nature 1996. 383: 86-89.
    • (1996) Nature , vol.383 , pp. 86-89
    • Hopken, U.E.1    Lu, B.2    Gerard, N.P.3    Gerard, C.4
  • 31
    • 28844434626 scopus 로고    scopus 로고
    • An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2
    • Gerard, N. P., Lu, B., Liu, P., Craig, S., Fujiwara, Y., Okinaga, S. and Gerard, C., An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2. J. Biol. Chem. 2005. 280: 39677-39680.
    • (2005) J. Biol. Chem. , vol.280 , pp. 39677-39680
    • Gerard, N.P.1    Lu, B.2    Liu, P.3    Craig, S.4    Fujiwara, Y.5    Okinaga, S.6    Gerard, C.7
  • 32


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.