Hepatic stellate cells inhibit t cells through active TGF-β1 from a cell surface-bound latent TGF-β1/GARP complex

Journal of Immunology

Volumn 195, Issue 6, 2015, Pages 2648-2656

  Li, Yan ^a   Kim, Byung Gyu ^b   Qian, Shiguang ^a   Letterio, John J ^b   Fung, John J ^a   Lu, Lina ^a   Lin, Feng ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; GAMMA INTERFERON; GLYCOPROTEIN A REPETITION PREDOMINANT; LATENT TRANSFORMING GROWTH FACTOR BETA1; PROGRAMMED DEATH 1 LIGAND 1; SHORT HAIRPIN RNA; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; LRRC32 PROTEIN, MOUSE; MEMBRANE PROTEIN; PROTEIN BINDING; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL INTERACTION; CELL ISOLATION; CELL PROLIFERATION; CELL SURFACE; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EFFECTOR CELL; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOREGULATION; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY T LYMPHOCYTE; STELLATE CELL; T CELL INHIBITION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; ENZYME ACTIVATION; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; LIVER; LIVER CIRRHOSIS; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOLOGY; RNA INTERFERENCE; SECRETION (PROCESS); SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; ENZYME ACTIVATION; HEPATIC STELLATE CELLS; HUMANS; INFLAMMATION; INTERFERON-GAMMA; LIVER; LIVER CIRRHOSIS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN BINDING; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84941752051     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500139     Document Type: Article

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