NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Flowers, Antwoine ^a   Lee, Jea Young ^a   Acosta, Sandra ^a   Hudson, Charles ^b   Small, Brent ^c   Sanberg, Cyndy D ^d   Bickford, Paula C ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d Natura Therapeutics Inc ^*  (United States)

Author keywords

Dentate gyrus subgranular zone; Neuroinflammation; NT 020; Polyphenols; Subventricular zone; Wnt pathway; catenin

Indexed keywords

BETA CATENIN; DOUBLECORTIN; HEME OXYGENASE 1; NT 020; POLYPHENOL; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; WNT PROTEIN; ACTIN BINDING PROTEIN; AIF1 PROTEIN, RAT; CALCIUM BINDING PROTEIN; CARNOSINE; COLECALCIFEROL; CYTOKINE; DOUBLECORTIN PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NERVE PROTEIN; NEUROPEPTIDE; NFE2L2 PROTEIN, MOUSE; NT020 FORMULA; PLANT EXTRACT; SIGNAL PEPTIDE;

AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN TISSUE; CELL LABELING; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; DIET SUPPLEMENTATION; GENE EXPRESSION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING; MALE; MEMORY; MICROGLIA; NERVE CELL; NERVOUS SYSTEM INFLAMMATION; NEURAL STEM CELL; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEM CELL NICHE; SUBVENTRICULAR ZONE; TASK PERFORMANCE; WNT SIGNALING PATHWAY; AGING; ANIMAL; BIOLOGY; CYTOLOGY; DRUG EFFECTS; FISCHER 344 RAT; GENETICS; INFLAMMATION; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; PHYSIOLOGY;

AGING; ANIMALS; BETA CATENIN; CALCIUM-BINDING PROTEINS; CARNOSINE; CELL PROLIFERATION; CHOLECALCIFEROL; COMPUTATIONAL BIOLOGY; CYTOKINES; DENTATE GYRUS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICROFILAMENT PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; NERVE TISSUE PROTEINS; NEUROGENESIS; NEUROPEPTIDES; NF-E2-RELATED FACTOR 2; PLANT EXTRACTS; RATS; RATS, INBRED F344; WNT SIGNALING PATHWAY;

EID: 84941637837     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0395-4     Document Type: Article

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