The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer

Journal of Biological Chemistry

Volumn 290, Issue 37, 2015, Pages 22649-22661

  Li, Hang ^a   Liu, Qian ^a   Wang, Zhen ^a   Fang, Runping ^a   Shen, Yu ^a   Cai, Xiaoli ^a   Gao, Yuen ^a   Li, Yinghui ^a   Zhang, Xiaodong ^a   Ye, Lihong ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; FEEDBACK; PROTEINS;

ACETYL TRANSFERASE; BREAST CANCER CELLS; EXPRESSION LEVELS; MCF-7 BREAST CANCER CELLS; NEGATIVE FEEDBACK LOOP; OVER-EXPRESSION; PROMOTER ACTIVITIES; TUMOR SUPPRESSORS;

DISEASES;

E1A ASSOCIATED P300 PROTEIN; HEPATITIS B X INTERACTING PROTEIN; MESSENGER RNA; ONCOPROTEIN; PROTEIN MDM2; PROTEIN P53; UNCLASSIFIED DRUG; HBXIP PROTEIN, HUMAN; MDM2 PROTEIN, HUMAN; RNA; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TP53 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; UPREGULATION; BIOSYNTHESIS; BREAST TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MDM2; RNA, MESSENGER; RNA, NEOPLASM; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84941595652     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.658468     Document Type: Article

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