Characterization of the p300 Taz2-p53 TAD2 Complex and Comparison with the p300 Taz2-p53 TAD1 Complex

Biochemistry

Volumn 54, Issue 11, 2015, Pages 2001-2010

  Miller Jenkins, Lisa M ^a   Feng, Hanqiao ^a   Durell, Stewart R ^a   Tagad, Harichandra D ^a   Mazur, Sharlyn J ^a   Tropea, Joseph E ^b   Bai, Yawen ^a,c   Appella, Ettore ^a,c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c Macromolecular Crystallography Laboratory National Cancer Institute ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOBILE SECURITY;

COMPLEX FORMATIONS; HISTONE ACETYLTRANSFERASE P300; ISOTHERMAL TITRATION CALORIMETRY; MUTATIONAL ANALYSIS; N-TERMINAL TRANSACTIVATION; PROTEIN INTERACTION; SOLUTION STRUCTURES; TRANSCRIPTIONAL ACTIVITY;

CHLORINE COMPOUNDS;

CHLORIDE ION; HISTONE ACETYLTRANSFERASE PCAF; MUTANT PROTEIN; PROTEIN; PROTEIN P53; PROTEIN TAD1; PROTEIN TAD2; PROTEIN TAZ2; UNCLASSIFIED DRUG; E1A ASSOCIATED P300 PROTEIN; EP300 PROTEIN, HUMAN; HISTONE ACETYLTRANSFERASE; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN; TP53 PROTEIN, HUMAN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HYDROGEN BOND; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; MUTATIONAL ANALYSIS; NITROGEN NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTON NUCLEAR MAGNETIC RESONANCE; STATIC ELECTRICITY; TRANSACTIVATION; AMINO ACID SUBSTITUTION; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DIFFERENTIAL SCANNING CALORIMETRY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PROTEIN QUATERNARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; CALORIMETRY, DIFFERENTIAL SCANNING; E1A-ASSOCIATED P300 PROTEIN; HISTONE ACETYLTRANSFERASES; HUMANS; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84925446111     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00044     Document Type: Article

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