-
1
-
-
33646807832
-
The P53 pathway: What questions remain to be explored?
-
Levine, A. J., Hu, W. & Feng, Z. The P53 pathway: what questions remain to be explored? Cell Death Differ. 13, 1027-1036 (2006).
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1027-1036
-
-
Levine, A.J.1
Hu, W.2
Feng, Z.3
-
2
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden, K. H. & Prives, C. Blinded by the light: the growing complexity of p53. Cell 137, 413-431 (2009).
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
3
-
-
1842862755
-
TP53 mutation spectra and load: A tool for generating hypotheses on the etiology of cancer
-
Olivier, M., Hussain, S. P., Caron de Fromentel, C., Hainaut, P. & Harris, C. C. TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer. IARC Sci. Publ. 247-270 (2004).
-
(2004)
IARC Sci. Publ.
, pp. 247-270
-
-
Olivier, M.1
Hussain, S.P.2
Caron De Fromentel, C.3
Hainaut, P.4
Harris, C.C.5
-
4
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin, D. et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250, 1233-1238 (1990).
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
-
5
-
-
34047247060
-
A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells
-
Hu, W. et al. A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells. Cancer Res. 67, 2757-2765 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 2757-2765
-
-
Hu, W.1
-
6
-
-
8844278362
-
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
-
Bond, G. L. et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 119, 591-602 (2004).
-
(2004)
Cell
, vol.119
, pp. 591-602
-
-
Bond, G.L.1
-
7
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
Harris, S. L. & Levine, A. J. The p53 pathway: positive and negative feedback loops. Oncogene 24, 2899-2908 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
8
-
-
58749094954
-
Targeting Mdm2 and Mdmx in cancer therapy: Better living through medicinal chemistry?
-
Wade, M. & Wahl, G. M. Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry? Mol. Cancer Res. 7, 1-11 (2009).
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 1-11
-
-
Wade, M.1
Wahl, G.M.2
-
9
-
-
0037459377
-
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
-
Leng, R. P. et al. Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell 112, 779-791 (2003).
-
(2003)
Cell
, vol.112
, pp. 779-791
-
-
Leng, R.P.1
-
10
-
-
18544385947
-
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23
-
Li, J. et al. Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23. Nat. Genet. 31, 133-134 (2002).
-
(2002)
Nat. Genet.
, vol.31
, pp. 133-134
-
-
Li, J.1
-
11
-
-
9744227111
-
Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer
-
Duan, W. et al. Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer. J. Natl Cancer Inst. 96, 1718-1721 (2004).
-
(2004)
J. Natl Cancer Inst.
, vol.96
, pp. 1718-1721
-
-
Duan, W.1
-
12
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal, A. et al. Cancer statistics, 2009. CA Cancer J. Clin. 59, 225-249 (2009).
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
-
13
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E. R. & Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell 61, 759-767 (1990).
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
14
-
-
0037220169
-
TP53 mutation in colorectal cancer
-
Iacopetta, B. TP53 mutation in colorectal cancer. Hum. Mutat. 21, 271-276 (2003).
-
(2003)
Hum. Mutat.
, vol.21
, pp. 271-276
-
-
Iacopetta, B.1
-
15
-
-
0034775927
-
Ferredoxin reductase affects p53-dependent, 5-fluorouracilinduced apoptosis in colorectal cancer cells
-
Hwang, P. M. et al. Ferredoxin reductase affects p53-dependent, 5-fluorouracilinduced apoptosis in colorectal cancer cells. Nat. Med. 7, 1111-1117 (2001).
-
(2001)
Nat. Med.
, vol.7
, pp. 1111-1117
-
-
Hwang, P.M.1
-
16
-
-
0027944206
-
P53 status and the efficacy of cancer therapy in vivo
-
Lowe, S. W. et al. p53 status and the efficacy of cancer therapy in vivo. Science 266, 807-810 (1994).
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
-
17
-
-
0034895979
-
P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma
-
Elsaleh, H. et al. P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin. Cancer Res. 7, 1343-1349 (2001).
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1343-1349
-
-
Elsaleh, H.1
-
18
-
-
32544444419
-
The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: Influence of tumor site, type of mutation, and adjuvant treatment
-
Russo, A. et al. The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment. J. Clin. Oncol. 23, 7518-7528 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 7518-7528
-
-
Russo, A.1
-
19
-
-
0037242690
-
The unsolved enigmas of leukemia inhibitory factor
-
Metcalf, D. The unsolved enigmas of leukemia inhibitory factor. Stem Cells 21, 5-14 (2003).
-
(2003)
Stem Cells
, vol.21
, pp. 5-14
-
-
Metcalf, D.1
-
20
-
-
0024205842
-
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
-
Williams, R. L. et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336, 684-687 (1988).
-
(1988)
Nature
, vol.336
, pp. 684-687
-
-
Williams, R.L.1
-
21
-
-
0026768292
-
Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor
-
Stewart, C. L. et al. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 359, 76-79 (1992).
-
(1992)
Nature
, vol.359
, pp. 76-79
-
-
Stewart, C.L.1
-
22
-
-
46349097234
-
Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway
-
Takahashi, Y. et al. Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway. Mol. Endocrinol. 22, 1673-1681 (2008).
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 1673-1681
-
-
Takahashi, Y.1
-
23
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich, P. C. et al. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem. J. 374, 1-20 (2003).
-
(2003)
Biochem. J.
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
-
24
-
-
33646549601
-
Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells
-
Watanabe, S. et al. Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene 25, 2697-2707 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 2697-2707
-
-
Watanabe, S.1
-
25
-
-
36749081541
-
P53 regulates maternal reproduction through LIF
-
Hu, W., Feng, Z., Teresky, A. K. & Levine, A. J. p53 regulates maternal reproduction through LIF. Nature 450, 721-724 (2007).
-
(2007)
Nature
, vol.450
, pp. 721-724
-
-
Hu, W.1
Feng, Z.2
Teresky, A.K.3
Levine, A.J.4
-
26
-
-
77955881567
-
The role of p53 gene family in reproduction
-
Hu, W. The role of p53 gene family in reproduction. Cold Spring Harb. Perspect. Biol. 1, a001073 (2009).
-
(2009)
Cold Spring Harb. Perspect. Biol.
, vol.1
, pp. a001073
-
-
Hu, W.1
-
27
-
-
67649844319
-
Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans
-
Kang, H. J. et al. Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans. Proc. Natl Acad. Sci. USA 106, 9761-9766 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 9761-9766
-
-
Kang, H.J.1
-
28
-
-
79960162178
-
Regulation of female reproduction by p53 and its family members
-
Feng, Z. et al. Regulation of female reproduction by p53 and its family members. FASEB J. 25, 2245-2255 (2011).
-
(2011)
FASEB J.
, vol.25
, pp. 2245-2255
-
-
Feng, Z.1
-
29
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz, F. et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J. Clin. Invest. 104, 263-269 (1999).
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 263-269
-
-
Bunz, F.1
-
30
-
-
33745475219
-
Id-1 promotes proliferation of p53-deficient esophageal cancer cells
-
Hui, C. M. et al. Id-1 promotes proliferation of p53-deficient esophageal cancer cells. Int. J. Cancer 119, 508-514 (2006).
-
(2006)
Int. J. Cancer
, vol.119
, pp. 508-514
-
-
Hui, C.M.1
-
31
-
-
0032960948
-
Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: Roles in inflammation and injury
-
Gadient, R. A. & Patterson, P. H. Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: roles in inflammation and injury. Stem Cells 17, 127-137 (1999).
-
(1999)
Stem Cells
, vol.17
, pp. 127-137
-
-
Gadient, R.A.1
Patterson, P.H.2
-
32
-
-
33846981871
-
STAT3 mRNA and protein expression in colorectal cancer: Effects on STAT3-inducible targets linked to cell survival and proliferation
-
Lassmann, S. et al. STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation. J. Clin. Pathol. 60, 173-179 (2007).
-
(2007)
J. Clin. Pathol.
, vol.60
, pp. 173-179
-
-
Lassmann, S.1
-
33
-
-
82655189564
-
STAT3 is necessary for proliferation and survival in colon cancerinitiating cells
-
Lin, L. et al. STAT3 is necessary for proliferation and survival in colon cancerinitiating cells. Cancer Res. 71, 7226-7237 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 7226-7237
-
-
Lin, L.1
-
34
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
Grivennikov, S. et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 15, 103-113 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
-
35
-
-
58649101347
-
Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
-
Bollrath, J. et al. gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 15, 91-102 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 91-102
-
-
Bollrath, J.1
-
36
-
-
23844503025
-
Role of Stat3 in regulating p53 expression and function
-
Niu, G. et al. Role of Stat3 in regulating p53 expression and function. Mol. Cell. Biol. 25, 7432-7440 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 7432-7440
-
-
Niu, G.1
-
37
-
-
0037085441
-
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
-
Korchynskyi, O. & ten Dijke, P. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J. Biol. Chem. 277, 4883-4891 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4883-4891
-
-
Korchynskyi, O.1
Ten Dijke, P.2
-
38
-
-
0036479133
-
Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene
-
Lopez-Rovira, T., Chalaux, E., Massague, J., Rosa, J. L. & Ventura, F. Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene. J. Biol. Chem. 277, 3176-3185 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3176-3185
-
-
Lopez-Rovira, T.1
Chalaux, E.2
Massague, J.3
Rosa, J.L.4
Ventura, F.5
-
39
-
-
42049092982
-
Regulation of Id1 expression by SRC: Implications for targeting of the bone morphogenetic protein pathway in cancer
-
Gautschi, O. et al. Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer. Cancer Res. 68, 2250-2258 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 2250-2258
-
-
Gautschi, O.1
-
40
-
-
0029914835
-
Transcription of the dominant-negative helix-loophelix protein Id1 is regulated by a protein complex containing the immediateearly response gene Egr-1
-
Tournay, O. & Benezra, R. Transcription of the dominant-negative helix-loophelix protein Id1 is regulated by a protein complex containing the immediateearly response gene Egr-1. Mol. Cell. Biol. 16, 2418-2430 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2418-2430
-
-
Tournay, O.1
Benezra, R.2
-
41
-
-
77953147195
-
Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: A distinct differentiation pattern from that of medulloblastomas
-
Phi, J. H. et al. Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas. J. Neurosurg. Pediatrics 5, 608-614 (2010).
-
(2010)
J. Neurosurg. Pediatrics
, vol.5
, pp. 608-614
-
-
Phi, J.H.1
-
42
-
-
0025238437
-
The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
-
Benezra, R., Davis, R. L., Lockshon, D., Turner, D. L. & Weintraub, H. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 61, 49-59 (1990).
-
(1990)
Cell
, vol.61
, pp. 49-59
-
-
Benezra, R.1
Davis, R.L.2
Lockshon, D.3
Turner, D.L.4
Weintraub, H.5
-
43
-
-
33845760019
-
Regulation of angiogenesis by Id-1 through hypoxia-inducible factor-1alpha-mediated vascular endothelial growth factor up-regulation in hepatocellular carcinoma
-
Lee, T. K. et al. Regulation of angiogenesis by Id-1 through hypoxia-inducible factor-1alpha-mediated vascular endothelial growth factor up-regulation in hepatocellular carcinoma. Clin. Cancer Res. 12, 6910-6919 (2006).
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 6910-6919
-
-
Lee, T.K.1
-
44
-
-
3242758854
-
Id-1 expression induces androgen-independent prostate cancer cell growth through activation of epidermal growth factor receptor (EGF-R)
-
Ling, M. T. et al. Id-1 expression induces androgen-independent prostate cancer cell growth through activation of epidermal growth factor receptor (EGF-R). Carcinogenesis 25, 517-525 (2004).
-
(2004)
Carcinogenesis
, vol.25
, pp. 517-525
-
-
Ling, M.T.1
-
45
-
-
0043170868
-
Id-1 expression promotes cell survival through activation of NF-kappaB signalling pathway in prostate cancer cells
-
Ling, M. T. et al. Id-1 expression promotes cell survival through activation of NF-kappaB signalling pathway in prostate cancer cells. Oncogene 22, 4498-4508 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 4498-4508
-
-
Ling, M.T.1
-
46
-
-
79956090053
-
Expression of Id-1 is regulated by MCAM/MUC18: A missing link in melanoma progression
-
Zigler, M. et al. Expression of Id-1 is regulated by MCAM/MUC18: a missing link in melanoma progression. Cancer Res. 71, 3494-3504 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 3494-3504
-
-
Zigler, M.1
-
47
-
-
4043183391
-
Id genes and proteins as promising targets in cancer therapy
-
Fong, S., Debs, R. J. & Desprez, P. Y. Id genes and proteins as promising targets in cancer therapy. Trends Mol. Med. 10, 387-392 (2004).
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 387-392
-
-
Fong, S.1
Debs, R.J.2
Desprez, P.Y.3
-
48
-
-
3042781699
-
Id-1-induced Raf/MEK pathway activation is essential for its protective role against taxol-induced apoptosis in nasopharyngeal carcinoma cells
-
Cheung, H. W., Ling, M. T., Tsao, S. W., Wong, Y. C. & Wang, X. Id-1-induced Raf/MEK pathway activation is essential for its protective role against taxol-induced apoptosis in nasopharyngeal carcinoma cells. Carcinogenesis 25, 881-887 (2004).
-
(2004)
Carcinogenesis
, vol.25
, pp. 881-887
-
-
Cheung, H.W.1
Ling, M.T.2
Tsao, S.W.3
Wong, Y.C.4
Wang, X.5
-
49
-
-
67449088929
-
The role of Id-1 in chemosensitivity and epirubicin-induced apoptosis in bladder cancer cells
-
Hu, H. et al. The role of Id-1 in chemosensitivity and epirubicin-induced apoptosis in bladder cancer cells. Oncol. Rep. 21, 1053-1059 (2009).
-
(2009)
Oncol. Rep.
, vol.21
, pp. 1053-1059
-
-
Hu, H.1
-
50
-
-
84862143004
-
ID1 and ID3 regulate the self-renewal capacity of human colon cancer-initiating cells through p21
-
O'Brien, C. A. et al. ID1 and ID3 regulate the self-renewal capacity of human colon cancer-initiating cells through p21. Cancer Cell 21, 777-792 (2012).
-
(2012)
Cancer Cell
, vol.21
, pp. 777-792
-
-
O'Brien, C.A.1
-
51
-
-
57049152346
-
Id-1: Regulator of EGFR and VEGF and potential target for colorectal cancer therapy
-
Meteoglu, I., Meydan, N. & Erkus, M. Id-1: regulator of EGFR and VEGF and potential target for colorectal cancer therapy. J. Exp. Clin. Cancer Res. 27, 69 (2008).
-
(2008)
J. Exp. Clin. Cancer Res.
, vol.27
, pp. 69
-
-
Meteoglu, I.1
Meydan, N.2
Erkus, M.3
-
52
-
-
2442690993
-
Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF)
-
Gearing, D. P. et al. Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF). EMBO J. 6, 3995-4002 (1987).
-
(1987)
EMBO J.
, vol.6
, pp. 3995-4002
-
-
Gearing, D.P.1
-
53
-
-
23944433875
-
Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells
-
Fitzgerald, J. S. et al. Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells. Int. J. Biochem. Cell Biol. 37, 2284-2296 (2005).
-
(2005)
Int. J. Biochem. Cell Biol.
, vol.37
, pp. 2284-2296
-
-
Fitzgerald, J.S.1
-
54
-
-
84896886438
-
LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway
-
Li, X. et al. LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway. Oncotarget 5, 788-801 (2014).
-
(2014)
Oncotarget
, vol.5
, pp. 788-801
-
-
Li, X.1
-
55
-
-
84890110205
-
Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance
-
Liu, S. C. et al. Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance. J. Clin. Invest. 123, 5269-5283 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 5269-5283
-
-
Liu, S.C.1
-
56
-
-
60449089627
-
A role for leukemia inhibitory factor in melanoma-induced bone metastasis
-
Maruta, S. et al. A role for leukemia inhibitory factor in melanoma-induced bone metastasis. Clin. Exp. Metastasis 26, 133-141 (2009).
-
(2009)
Clin. Exp. Metastasis
, vol.26
, pp. 133-141
-
-
Maruta, S.1
-
57
-
-
33947276285
-
Leukemia inhibitory factor: A newly identified metastatic factor in rhabdomyosarcomas
-
Wysoczynski, M. et al. Leukemia inhibitory factor: a newly identified metastatic factor in rhabdomyosarcomas. Cancer Res. 67, 2131-2140 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 2131-2140
-
-
Wysoczynski, M.1
-
58
-
-
57749115895
-
The high-mobility group A1a/signal transducer and activator of transcription-3 axis: An achilles heel for hematopoietic malignancies?
-
Hillion, J. et al. The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Res. 68, 10121-10127 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 10121-10127
-
-
Hillion, J.1
-
59
-
-
80053635472
-
Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
-
Zhang, C. et al. Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect. Proc. Natl Acad. Sci. USA 108, 16259-16264 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 16259-16264
-
-
Zhang, C.1
-
60
-
-
84890950891
-
Spliced MDM2 isoforms promote mutant p53 accumulation and gain-of-function in tumorigenesis
-
Zheng, T. et al. Spliced MDM2 isoforms promote mutant p53 accumulation and gain-of-function in tumorigenesis. Nat. Commun. 4, 2996 (2013).
-
(2013)
Nat. Commun.
, vol.4
, pp. 2996
-
-
Zheng, T.1
-
61
-
-
77249143960
-
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer
-
Smith, J. J. et al. Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology 138, 958-968 (2010).
-
(2010)
Gastroenterology
, vol.138
, pp. 958-968
-
-
Smith, J.J.1
-
62
-
-
84863125635
-
Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of beta-catenin
-
Freeman, T. J. et al. Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of beta-catenin. Gastroenterology 142, 562-571 e562 (2012).
-
(2012)
Gastroenterology
, vol.142
, pp. 562-571e562
-
-
Freeman, T.J.1
-
63
-
-
84878302099
-
Gene expression classification of colon cancer into molecular subtypes: Characterization, validation, and prognostic value
-
Marisa, L. et al. Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value. PLoS Med. 10, e1001453 (2013).
-
(2013)
PLoS Med.
, vol.10
, pp. e1001453
-
-
Marisa, L.1
|