The oncoprotein HBXIP upregulates Lin28B via activating TF II D to promote proliferation of breast cancer cells

International Journal of Cancer

Volumn 133, Issue 6, 2013, Pages 1310-1322

  Liu, Qian ^a   Bai, Xiao ^a   Li, Hang ^a   Zhang, Yingyi ^a   Zhao, Yu ^a   Zhang, Xiaodong ^a   Ye, Lihong ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

carcinogenesis; HBXIP; Lin28B; miRNA 520b; TF II D

Indexed keywords

GLUTATHIONE TRANSFERASE; HEPATITIS B VIRUS X PROTEIN; LIN28B PROTEIN; MICRORNA; MICRORNA 520B; RNA BINDING PROTEIN; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR IID; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CARCINOGENESIS; CELL STRAIN MCF 7; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SUBUNIT; PROTEIN TARGETING; TUMOR GROWTH; UPREGULATION;

CARCINOGENESIS; HBXIP; LIN28B; MIRNA-520B; TF II D;

ACTIVE TRANSPORT, CELL NUCLEUS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICRORNAS; PROMOTER REGIONS, GENETIC; RNA-BINDING PROTEINS; TRANSCRIPTION FACTOR TFIID; UP-REGULATION;

EID: 84879984189     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28154     Document Type: Article

References (48)

1. Melegari M, Scaglioni PP, Wands JR,. Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication. J Virol 1998; 72: 1737-43.
2. Marusawa H, Matsuzawa SI, Welsh K, et al. HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J 2003; 22: 2729-40.
3. Fujii R, Zhu C, Wen Y, et al. HBXIP, cellular target of hepatitis B virus oncoprotein, is a regulator of centrosome dynamics and cytokinesis. Cancer Res 2006; 66: 9099-107.
4. Wang FZ, Sha L, Zhang WY, et al. Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells. Acta Pharmacol Sin 2007; 28: 431-8.
5. Wang FZ, Fei HR, Lian LH, et al. Hepatitis B x-interacting protein induces HepG2 cell proliferation through activation of the phosphatidylinositol 3-kinase/Akt pathway. Exp Biol Med 2011; 236: 62-9.
6. Hu N, Zhang J, Cui W, et al. miR-520b regulates migration of breast cancer cells through targeting hepatitis B X-interacting protein and interleukin-8. J Biol Chem 2011; 286: 13714-22.
7. Liu S, Li L, Zhang Y, et al. The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells. J Biol Chem 2012; 287: 30228-39.
8. Guo Y, Chen Y, Ito H, et al. Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene 2006; 384: 51-61.
9. Piskounova E, Polytarchou C, Thornton JE, et al. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell 2011; 147: 1066-79.
10. Leppert U, Henke W, Huang X, et al. Post-transcriptional fine-tuning of COP9 signalosome subunit biosynthesis is regulated by the c-Myc/Lin28B/let-7 pathway. J Mol Biol 2011; 409: 710-21.
11. Viswanathan SR, Daley GQ,. Lin28: A microRNA regulator with a macro role. Cell 2010; 140: 445-9.
12. Iliopoulos D, Hirsch HA, Struhl K,. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 2009; 139: 693-706.
13. Bussing I, Slack FJ, Grosshans H,. let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 2008; 14: 400-9.
14. Viswanathan SR, Powers JT, Einhorn W, et al. Lin28 enhances tumorigenesis and is associated with advanced human malignancies. Nat Genet 2009; 41: 843-48.
15. Lu L, Katsaros D, Shaverdashvili K, et al. Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II. Eur J Cancer 2009; 45: 2212-8.
16. Wang YC, Chen YL, Yuan RH, et al. Lin-28B expression promotes transformation and invasion in human hepatocellular carcinoma. Carcinogenesis 2010; 31: 1516-22.
17. King C, Cuatrecasas M, Castells A, et al. Lin28b promotes colon cancer progression and metastasis. Cancer Res 2011; 71: 4260-8.
18. Liang L, Wong CM, Ying Q, et al. MicroRNA-125b Suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B. Hepatology. 2010; 52: 1731-40.
19. Hamano R, Miyata H, Yamasaki M, et al. High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer. Br J Cancer 2012; 106: 1415-23.
20. Chen AX, Yu KD, Fan L, et al. Germline genetic variants disturbing the Let-7/LIN28 double-negative feedback loop alter breast cancer susceptibility. PLoS Genet 2011; 7: e1002259.
21. Malik F, Korkaya H, Clouthier SG, et al. Lin28 and HER2: Two stem cell regulators conspire to drive aggressive breast cancer. Cell Cycle 2012; 11: 2780-1.
22. Sakurai M, Miki Y, Masuda M, et al. LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. J Steroid Biochem Mol Biol 2012; 131: 101-6.
23. Papai G, Weil PA, Schultz P,. New insights into the function of transcription factor TFIID from recent structural studies. Curr Opin Genet Dev 2011; 21: 219-24.
24. Tsai FT, Sigler PB,. Structural basis of preinitiation complex assembly on human pol II promoters. EMBO J 2000; 19: 25-36.
25. Apone LM, Green MR,. Transcription sans TBP. Nature 1998; 393: 114-5.
26. Tora L, Timmers HT,. The TATA box regulates TATA-binding protein (TBP) dynamics in vivo. Trends Biochem Sci 2010; 35: 309-14.
27. Moqtaderi Z, Bai Y, Poon D, et al. TBP-associated factors are not generally required for transcriptional activation in yeast. Nature 1996; 383: 188-91.
28. Tatarakis A, Margaritis T, Martinez-Jimenez CP, et al. Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. Mol Cell 2008; 31: 531-43.
29. D'Alessio JA, Wright KJ, Tjian R,. Shifting players and paradigms in cell-specific transcription. Mol Cell 2009; 36: 924-31.
30. Zhong S, Johnson DL,. The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits. Proc Natl Acad Sci U S A 2009; 106: 12682-7.
31. Chang TC, Zeitels LR, Hwang HW, et al. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A 2009; 106: 3384-9.
32. Zhang S, Shan C, Kong G, et al. MicroRNA-520e suppresses growth of hepatoma cells by targeting the NF-kappaB-inducing kinase (NIK). Oncogene 2012; 31: 3607-20.
33. Zhang T, Zhang J, You X, et al. Hepatitis B virus X protein (HBx) modulates oncogene YAP via CREB to promote growth of hepatoma cells. Hepatology 2012; 56: 2051-9.
34. Raha T, Cheng SW, Green MR,. HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs. PLoS Biol 2005; 3: e44.
35. Nelson JD, Denisenko O, Bomsztyk K,. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat Protoc 2006; 1: 179-85.
36. Woo AJ, Dods JS, Susanto E, et al. A proteomics approach for the identification of DNA binding activities observed in the electrophoretic mobility shift assay. Mol Cell Proteomics 2002; 1: 472-8.
37. Vikis HG, Guan KL,. Glutathione-S-transferase-fusion based assays for studying protein-protein interactions. Methods Mol Biol 2004; 261: 175-86.
38. Trusca VG, Florea IC, Kardassis D, et al. STAT1 Interacts with RXRalpha to upregulate ApoCII gene expression in macrophages. PLoS One 2012; 7: e40463.
39. Dangi-Garimella S, Yun J, Eves EM, et al. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J 2009; 28: 347-58.
40. Horak CE, Mahajan MC, Luscombe NM, et al. GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis. Proc Natl Acad Sci U S A 2002; 99: 2924-9.
41. Smale ST, Kadonaga JT,. The RNA polymerase II core promoter. Annu Rev Biochem 2003; 72: 449-79.
42. John S, Sabo PJ, Thurman RE, et al. Chromatin accessibility pre-determines glucocorticoid receptor binding patterns. Nat Genet 2011; 43: 264-8.
43. Aceto N, Sausgruber N, Brinkhaus H, et al. Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop. Nat Med 2012; 18: 529-37.
44. Prahallad A, Sun C, Huang S, et al. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature 2012; 483: 100-3.
45. Park S, Zhao D, Hatanpaa KJ, et al. RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN. Cancer Res 2009; 69: 4107-11.
46. Yu F, Yao H, Zhu P, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007; 131: 1109-23.
47. Viswanathan SR, Daley GQ, Gregory RI,. Selective blockade of microRNA processing by Lin28. Science 2008; 320: 97-100.
48. Heo I, Joo C, Kim YK, et al. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 2009; 138: 696-708.