Deficient Wnt signalling triggers striatal synaptic degeneration and impaired motor behaviour in adult mice

Nature Communications

Volumn 5, Issue , 2014, Pages

  Galli, Soledad ^a   Lopes, Douglas M ^a   Ammari, Rachida ^a   Kopra, Jaakko ^b   Millar, Sarah E ^c   Gibb, Alasdair ^a   Salinas, Patricia C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; DICKKOPF 1 PROTEIN; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; POSTSYNAPTIC DENSITY PROTEIN 95; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR GLUTAMATE TRANSPORTER 2; VESICULAR MONOAMINE TRANSPORTER 2; WNT PROTEIN; AMPHETAMINE DERIVATIVE; DKK1 PROTEIN, MOUSE; DOPAMINE; DOXYCYCLINE; SIGNAL PEPTIDE;

CELLS AND CELL COMPONENTS; DISEASE INCIDENCE; GENE EXPRESSION; NERVOUS SYSTEM DISORDER; PROTEIN; RODENT; SYMPTOM;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; DOPAMINE RELEASE; GLUTAMATERGIC SYNAPSE; IN VIVO STUDY; LOCOMOTION; MOTOR DYSFUNCTION; MOUSE; NERVE DEGENERATION; NERVE FIBER; NEUROTRANSMITTER RELEASE; NONHUMAN; SYNAPSE VESICLE; WNT SIGNALING PATHWAY; ANIMAL; AXON; CHEMISTRY; FEMALE; FLUORESCENCE MICROSCOPY; HETEROZYGOTE; KNOCKOUT MOUSE; MALE; METABOLISM; MOTOR PERFORMANCE; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SYNAPSE; TRANSGENIC MOUSE;

MUS;

AMPHETAMINES; ANIMALS; AXONS; CELL DEATH; CORPUS STRIATUM; DOPAMINE; DOXYCYCLINE; FEMALE; HETEROZYGOTE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MOTOR SKILLS; NEURODEGENERATIVE DISEASES; NEURONS; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SIGNAL TRANSDUCTION; SYNAPSES; WNT PROTEINS;

EID: 84941577888     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5992     Document Type: Article

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