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Volumn 28, Issue 5, 2013, Pages 569-575

The VPS35 gene and Parkinson's disease

Author keywords

DMT1; Parkinson's disease; Retromer; VPS35; Wnt

Indexed keywords

BETA CATENIN; LEUCINE RICH REPEAT KINASE 2; MESSENGER RNA; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; PARKIN; WNT PROTEIN;

EID: 84877923497     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25430     Document Type: Review
Times cited : (72)

References (76)
  • 1
    • 33745919520 scopus 로고    scopus 로고
    • Epidemiology of Parkinson's disease
    • de Lau LM, Breteler MM. Epidemiology of Parkinson's disease. Lancet Neurol. 2006;5:525-535.
    • (2006) Lancet Neurol. , vol.5 , pp. 525-535
    • de Lau, L.M.1    Breteler, M.M.2
  • 2
    • 41149163183 scopus 로고    scopus 로고
    • Parkinson's disease: clinical features and diagnosis
    • Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry. 2008;79:368-376.
    • (2008) J Neurol Neurosurg Psychiatry. , vol.79 , pp. 368-376
    • Jankovic, J.1
  • 3
    • 72149101615 scopus 로고    scopus 로고
    • Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms
    • Rodriguez-Oroz MC, Jahanshahi M, Krack P, et al. Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms. Lancet Neurol. 2009;8:1128-1139.
    • (2009) Lancet Neurol. , vol.8 , pp. 1128-1139
    • Rodriguez-Oroz, M.C.1    Jahanshahi, M.2    Krack, P.3
  • 4
    • 84863728773 scopus 로고    scopus 로고
    • Therapies in Parkinson's disease
    • Jankovic J, Poewe W. Therapies in Parkinson's disease. Curr Opin Neurol. 2012;25:433-447.
    • (2012) Curr Opin Neurol. , vol.25 , pp. 433-447
    • Jankovic, J.1    Poewe, W.2
  • 6
    • 84872590599 scopus 로고    scopus 로고
    • F-box only protein 7 gene in parkinsonian-pyramidal disease
    • Deng H, Liang H, Jankovic J. F-box only protein 7 gene in parkinsonian-pyramidal disease. Arch Neurol. 2012;70:20-24.
    • (2012) Arch Neurol. , vol.70 , pp. 20-24
    • Deng, H.1    Liang, H.2    Jankovic, J.3
  • 7
    • 84858693790 scopus 로고    scopus 로고
    • Role of Mendelian genes in "sporadic" Parkinson's disease
    • Lesage S, Brice A. Role of Mendelian genes in "sporadic" Parkinson's disease. Parkinsonism Relat Disord. 2012;18(Suppl 1):S66-S70.
    • (2012) Parkinsonism Relat Disord. , vol.18 , Issue.SUPPL. 1
    • Lesage, S.1    Brice, A.2
  • 9
    • 80051534540 scopus 로고    scopus 로고
    • A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease
    • Zimprich A, Benet-Pages A, Struhal W, et al. A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. Am J Hum Genet. 2011;89:168-175.
    • (2011) Am J Hum Genet. , vol.89 , pp. 168-175
    • Zimprich, A.1    Benet-Pages, A.2    Struhal, W.3
  • 10
    • 84861848453 scopus 로고    scopus 로고
    • Contribution of VPS35 genetic variability to LBD in the Flanders-Belgian population
    • Verstraeten A, Wauters E, Crosiers D, et al. Contribution of VPS35 genetic variability to LBD in the Flanders-Belgian population. Neurobiol Aging. 2012;33:1811-1844.
    • (2012) Neurobiol Aging. , vol.33 , pp. 1811-1844
    • Verstraeten, A.1    Wauters, E.2    Crosiers, D.3
  • 11
    • 84856956020 scopus 로고    scopus 로고
    • Screening for VPS35 mutations in Parkinson's disease
    • Sheerin UM, Charlesworth G, Bras J, et al. Screening for VPS35 mutations in Parkinson's disease. Neurobiol Aging. 2012;33:831-838.
    • (2012) Neurobiol Aging. , vol.33 , pp. 831-838
    • Sheerin, U.M.1    Charlesworth, G.2    Bras, J.3
  • 12
    • 84861697525 scopus 로고    scopus 로고
    • The Asp620asn mutation in VPS35 is not a common cause of familial Parkinson's disease
    • Guella I, Solda G, Cilia R, et al. The Asp620asn mutation in VPS35 is not a common cause of familial Parkinson's disease. Mov Disord. 2012;27:800-801.
    • (2012) Mov Disord. , vol.27 , pp. 800-801
    • Guella, I.1    Solda, G.2    Cilia, R.3
  • 13
    • 84862776825 scopus 로고    scopus 로고
    • Vacuolar protein sorting 35 Asp620Asn mutation is rare in the ethnic Chinese population with Parkinson's disease
    • Zhang Y, Chen S, Xiao Q, et al. Vacuolar protein sorting 35 Asp620Asn mutation is rare in the ethnic Chinese population with Parkinson's disease. Parkinsonism Relat Disord. 2012;18:638-640.
    • (2012) Parkinsonism Relat Disord. , vol.18 , pp. 638-640
    • Zhang, Y.1    Chen, S.2    Xiao, Q.3
  • 14
    • 84865610272 scopus 로고    scopus 로고
    • VPS35 gene variants are not associated with Parkinson's disease in the mainland Chinese population
    • Guo JF, Sun QY, Lv ZY, et al. VPS35 gene variants are not associated with Parkinson's disease in the mainland Chinese population. Parkinsonism Relat Disord. 2012;18:983-985.
    • (2012) Parkinsonism Relat Disord. , vol.18 , pp. 983-985
    • Guo, J.F.1    Sun, Q.Y.2    Lv, Z.Y.3
  • 15
    • 84860767366 scopus 로고    scopus 로고
    • Identification of VPS35 mutations replicated in French families with Parkinson disease
    • Lesage S, Condroyer C, Klebe S, et al. Identification of VPS35 mutations replicated in French families with Parkinson disease. Neurology. 2012;78:1449-1450.
    • (2012) Neurology. , vol.78 , pp. 1449-1450
    • Lesage, S.1    Condroyer, C.2    Klebe, S.3
  • 16
    • 84867363858 scopus 로고    scopus 로고
    • Frequency of the D620N Mutation in VPS35 in Parkinson Disease
    • Kumar KR, Weissbach A, Heldmann M, et al. Frequency of the D620N Mutation in VPS35 in Parkinson Disease. Arch Neurol. 2012;69:1360-1364.
    • (2012) Arch Neurol. , vol.69 , pp. 1360-1364
    • Kumar, K.R.1    Weissbach, A.2    Heldmann, M.3
  • 17
    • 84865286979 scopus 로고    scopus 로고
    • VPS35 mutation in Chinese Han patients with late-onset Parkinson's disease
    • Deng H, Xu H, Deng X, et al. VPS35 mutation in Chinese Han patients with late-onset Parkinson's disease. Eur J Neurol. 2012;19:e96-e97.
    • (2012) Eur J Neurol. , vol.19
    • Deng, H.1    Xu, H.2    Deng, X.3
  • 18
    • 84866598540 scopus 로고    scopus 로고
    • VPS35 mutation in Japanese patients with typical Parkinson's disease
    • Ando M, Funayama M, Li Y, et al. VPS35 mutation in Japanese patients with typical Parkinson's disease. Mov Disord. 2012;27:1413-1417.
    • (2012) Mov Disord. , vol.27 , pp. 1413-1417
    • Ando, M.1    Funayama, M.2    Li, Y.3
  • 19
    • 84870287920 scopus 로고    scopus 로고
    • A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants
    • Sharma M, Ioannidis JP, Aasly JO, et al. A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants. J Med Genet. 2012;49:721-726.
    • (2012) J Med Genet. , vol.49 , pp. 721-726
    • Sharma, M.1    Ioannidis, J.P.2    Aasly, J.O.3
  • 20
    • 84875265942 scopus 로고    scopus 로고
    • VPS35 Asp620Asn and EIF4G1 Arg1205His mutations are rare in Parkinson disease from Southwest China
    • Chen Y, Chen K, Song W, et al. VPS35 Asp620Asn and EIF4G1 Arg1205His mutations are rare in Parkinson disease from Southwest China. Neurobiol Aging. 2013;34:1709.e7-1709.e8.
    • (2013) Neurobiol Aging. , vol.34
    • Chen, Y.1    Chen, K.2    Song, W.3
  • 21
    • 28544441181 scopus 로고    scopus 로고
    • Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data
    • Khan NL, Jain S, Lynch JM, et al. Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data. Brain. 2005;128:2786-2796.
    • (2005) Brain. , vol.128 , pp. 2786-2796
    • Khan, N.L.1    Jain, S.2    Lynch, J.M.3
  • 24
    • 0034597661 scopus 로고    scopus 로고
    • Human homologues of yeast vacuolar protein sorting 29 and 35
    • Edgar AJ, Polak JM. Human homologues of yeast vacuolar protein sorting 29 and 35. Biochem Biophys Res Commun. 2000;277:622-630.
    • (2000) Biochem Biophys Res Commun. , vol.277 , pp. 622-630
    • Edgar, A.J.1    Polak, J.M.2
  • 25
    • 0034542766 scopus 로고    scopus 로고
    • Cloning and characterization of human VPS35 and mouse Vps35 and mapping of VPS35 to human chromosome 16q13-q21
    • Zhang P, Yu L, Gao J, et al. Cloning and characterization of human VPS35 and mouse Vps35 and mapping of VPS35 to human chromosome 16q13-q21. Genomics. 2000;70:253-257.
    • (2000) Genomics. , vol.70 , pp. 253-257
    • Zhang, P.1    Yu, L.2    Gao, J.3
  • 27
    • 79960184162 scopus 로고    scopus 로고
    • Recent advances in retromer biology
    • McGough IJ, Cullen PJ. Recent advances in retromer biology. Traffic. 2011;12:963-971.
    • (2011) Traffic. , vol.12 , pp. 963-971
    • McGough, I.J.1    Cullen, P.J.2
  • 28
    • 33846587097 scopus 로고    scopus 로고
    • Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors
    • Rojas R, Kametaka S, Haft CR, Bonifacino JS. Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. Mol Cell Biol. 2007;27:1112-1124.
    • (2007) Mol Cell Biol. , vol.27 , pp. 1112-1124
    • Rojas, R.1    Kametaka, S.2    Haft, C.R.3    Bonifacino, J.S.4
  • 30
    • 79960716101 scopus 로고    scopus 로고
    • Exit from the trans-Golgi network: from molecules to mechanisms
    • Anitei M, Hoflack B. Exit from the trans-Golgi network: from molecules to mechanisms. Curr Opin Cell Biol. 2011;23:443-451.
    • (2011) Curr Opin Cell Biol. , vol.23 , pp. 443-451
    • Anitei, M.1    Hoflack, B.2
  • 31
    • 2442530398 scopus 로고    scopus 로고
    • Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor
    • Arighi CN, Hartnell LM, Aguilar RC, Haft CR, Bonifacino JS. Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol. 2004;165:123-133.
    • (2004) J Cell Biol. , vol.165 , pp. 123-133
    • Arighi, C.N.1    Hartnell, L.M.2    Aguilar, R.C.3    Haft, C.R.4    Bonifacino, J.S.5
  • 32
    • 27244454163 scopus 로고    scopus 로고
    • Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2
    • Griffin CT, Trejo J, Magnuson T. Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2. Proc Natl Acad Sci U S A. 2005;102:15173-15177.
    • (2005) Proc Natl Acad Sci U S A. , vol.102 , pp. 15173-15177
    • Griffin, C.T.1    Trejo, J.2    Magnuson, T.3
  • 33
    • 77749254726 scopus 로고    scopus 로고
    • Retromer is required for apoptotic cell clearance by phagocytic receptor recycling
    • Chen D, Xiao H, Zhang K, et al. Retromer is required for apoptotic cell clearance by phagocytic receptor recycling. Science. 2010;327:1261-1264.
    • (2010) Science. , vol.327 , pp. 1261-1264
    • Chen, D.1    Xiao, H.2    Zhang, K.3
  • 34
    • 79961002971 scopus 로고    scopus 로고
    • A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion
    • Harterink M, Port F, Lorenowicz MJ, et al. A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion. Nat Cell Biol. 2011;13:914-923.
    • (2011) Nat Cell Biol. , vol.13 , pp. 914-923
    • Harterink, M.1    Port, F.2    Lorenowicz, M.J.3
  • 35
    • 35548969906 scopus 로고    scopus 로고
    • Functional architecture of the retromer cargo-recognition complex
    • Hierro A, Rojas AL, Rojas R, et al. Functional architecture of the retromer cargo-recognition complex. Nature. 2007;449:1063-1067.
    • (2007) Nature. , vol.449 , pp. 1063-1067
    • Hierro, A.1    Rojas, A.L.2    Rojas, R.3
  • 36
    • 35948987177 scopus 로고    scopus 로고
    • Structural features of vps35p involved in interaction with other subunits of the retromer complex
    • Restrepo R, Zhao X, Peter H, Zhang BY, Arvan P, Nothwehr SF. Structural features of vps35p involved in interaction with other subunits of the retromer complex. Traffic. 2007;8:1841-1853.
    • (2007) Traffic. , vol.8 , pp. 1841-1853
    • Restrepo, R.1    Zhao, X.2    Peter, H.3    Zhang, B.Y.4    Arvan, P.5    Nothwehr, S.F.6
  • 37
    • 35948964791 scopus 로고    scopus 로고
    • Dominant-negative behavior of mammalian Vps35 in yeast requires a conserved PRLYL motif involved in retromer assembly
    • Zhao X, Nothwehr S, Lara-Lemus R, Zhang BY, Peter H, Arvan P. Dominant-negative behavior of mammalian Vps35 in yeast requires a conserved PRLYL motif involved in retromer assembly. Traffic. 2007;8:1829-1840.
    • (2007) Traffic. , vol.8 , pp. 1829-1840
    • Zhao, X.1    Nothwehr, S.2    Lara-Lemus, R.3    Zhang, B.Y.4    Peter, H.5    Arvan, P.6
  • 38
    • 0033634771 scopus 로고    scopus 로고
    • Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes
    • Haft CR, de la Luz SM, Bafford R, Lesniak MA, Barr VA, Taylor SI. Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. Mol Biol Cell. 2000;11:4105-4116.
    • (2000) Mol Biol Cell. , vol.11 , pp. 4105-4116
    • Haft, C.R.1    de la Luz, S.M.2    Bafford, R.3    Lesniak, M.A.4    Barr, V.A.5    Taylor, S.I.6
  • 39
    • 22144490854 scopus 로고    scopus 로고
    • Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
    • Collins BM, Skinner CF, Watson PJ, Seaman MN, Owen DJ. Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly. Nat Struct Mol Biol. 2005;12:594-602.
    • (2005) Nat Struct Mol Biol. , vol.12 , pp. 594-602
    • Collins, B.M.1    Skinner, C.F.2    Watson, P.J.3    Seaman, M.N.4    Owen, D.J.5
  • 40
    • 27744576858 scopus 로고    scopus 로고
    • Model-guided microarray implicates the retromer complex in Alzheimer's disease
    • Small SA, Kent K, Pierce A, et al. Model-guided microarray implicates the retromer complex in Alzheimer's disease. Ann Neurol. 2005;58:909-919.
    • (2005) Ann Neurol. , vol.58 , pp. 909-919
    • Small, S.A.1    Kent, K.2    Pierce, A.3
  • 41
    • 84861230374 scopus 로고    scopus 로고
    • The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport
    • Bhalla A, Vetanovetz CP, Morel E, Chamoun Z, Di Paolo G, Small SA. The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport. Neurobiol Dis. 2012;47:126-134.
    • (2012) Neurobiol Dis. , vol.47 , pp. 126-134
    • Bhalla, A.1    Vetanovetz, C.P.2    Morel, E.3    Chamoun, Z.4    Di Paolo, G.5    Small, S.A.6
  • 42
    • 44449165118 scopus 로고    scopus 로고
    • Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Aβ accumulation
    • Muhammad A, Flores I, Zhang H, et al. Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Aβ accumulation. Proc Natl Acad Sci U S A. 2008;105:7327-7332.
    • (2008) Proc Natl Acad Sci U S A. , vol.105 , pp. 7327-7332
    • Muhammad, A.1    Flores, I.2    Zhang, H.3
  • 43
    • 84862907635 scopus 로고    scopus 로고
    • VPS35 haploinsufficiency increases Alzheimer's disease neuropathology
    • Wen L, Tang FL, Hong Y, et al. VPS35 haploinsufficiency increases Alzheimer's disease neuropathology. J Cell Biol. 2011;195:765-779.
    • (2011) J Cell Biol. , vol.195 , pp. 765-779
    • Wen, L.1    Tang, F.L.2    Hong, Y.3
  • 44
    • 84877919955 scopus 로고    scopus 로고
    • VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1
    • Wang CL, Tang FL, Peng Y, Shen CY, Mei L, Xiong WC. VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1. Biol Open. 2012;1:1248-1257.
    • (2012) Biol Open. , vol.1 , pp. 1248-1257
    • Wang, C.L.1    Tang, F.L.2    Peng, Y.3    Shen, C.Y.4    Mei, L.5    Xiong, W.C.6
  • 45
    • 0242363167 scopus 로고    scopus 로고
    • Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a
    • Castelo-Branco G, Wagner J, Rodriguez FJ, et al. Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci USA. 2003;100:12747-12752.
    • (2003) Proc Natl Acad Sci USA. , vol.100 , pp. 12747-12752
    • Castelo-Branco, G.1    Wagner, J.2    Rodriguez, F.J.3
  • 46
    • 75549087261 scopus 로고    scopus 로고
    • Emerging roles of Wnts in the adult nervous system
    • Inestrosa NC, Arenas E. Emerging roles of Wnts in the adult nervous system. Nat Rev Neurosci. 2010;11:77-86.
    • (2010) Nat Rev Neurosci. , vol.11 , pp. 77-86
    • Inestrosa, N.C.1    Arenas, E.2
  • 47
    • 84865411404 scopus 로고    scopus 로고
    • Inhibition of the canonical Wnt pathway by Dickkopf-1 contributes to the neurodegeneration in 6-OHDA-lesioned rats
    • Dun Y, Li G, Yang Y, et al. Inhibition of the canonical Wnt pathway by Dickkopf-1 contributes to the neurodegeneration in 6-OHDA-lesioned rats. Neurosci Lett. 2012;525:83-88.
    • (2012) Neurosci Lett. , vol.525 , pp. 83-88
    • Dun, Y.1    Li, G.2    Yang, Y.3
  • 48
    • 78650621911 scopus 로고    scopus 로고
    • Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
    • L'Episcopo F, Tirolo C, Testa N, et al. Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine model of Parkinson's disease. Neurobiol Dis. 2011;41:508-527.
    • (2011) Neurobiol Dis. , vol.41 , pp. 508-527
    • L'Episcopo, F.1    Tirolo, C.2    Testa, N.3
  • 49
    • 77955514552 scopus 로고    scopus 로고
    • Gene expression profiling in progressively MPTP-lesioned macaques reveals molecular pathways associated with sporadic Parkinson's disease
    • Ohnuki T, Nakamura A, Okuyama S, Nakamura S. Gene expression profiling in progressively MPTP-lesioned macaques reveals molecular pathways associated with sporadic Parkinson's disease. Brain Res. 2010;1346:26-42.
    • (2010) Brain Res. , vol.1346 , pp. 26-42
    • Ohnuki, T.1    Nakamura, A.2    Okuyama, S.3    Nakamura, S.4
  • 50
    • 34248595527 scopus 로고    scopus 로고
    • Effects of gender on nigral gene expression and Parkinson disease
    • Cantuti-Castelvetri I, Keller-McGandy C, Bouzou B, et al. Effects of gender on nigral gene expression and Parkinson disease. Neurobiol Dis. 2007;26:606-614.
    • (2007) Neurobiol Dis. , vol.26 , pp. 606-614
    • Cantuti-Castelvetri, I.1    Keller-McGandy, C.2    Bouzou, B.3
  • 51
    • 0037220599 scopus 로고    scopus 로고
    • Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
    • De Ferrari GV, Chacón MA, Barría MI, Garrido JL, et al. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Mol Psychiatry. 2003;8:195-208.
    • (2003) Mol Psychiatry. , vol.8 , pp. 195-208
    • De Ferrari, G.V.1    Chacón, M.A.2    Barría, M.I.3    Garrido, J.L.4
  • 52
    • 79960123794 scopus 로고    scopus 로고
    • A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection
    • 6:49
    • L'Episcopo F, Serapide MF, Tirolo C, et al. A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection. Mol Neurodegener. 2011;13:6:49.
    • (2011) Mol Neurodegener. , vol.13
    • L'Episcopo, F.1    Serapide, M.F.2    Tirolo, C.3
  • 53
    • 69749110516 scopus 로고    scopus 로고
    • Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling
    • Rawal N, Corti O, Sacchetti P, et al. Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling. Biochem Biophys Res Commun. 2009;388:473-478.
    • (2009) Biochem Biophys Res Commun. , vol.388 , pp. 473-478
    • Rawal, N.1    Corti, O.2    Sacchetti, P.3
  • 54
    • 70349576902 scopus 로고    scopus 로고
    • Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways
    • Sancho RM, Law BM, Harvey K. Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways. Hum Mol Genet. 2009;18:3955-3968.
    • (2009) Hum Mol Genet. , vol.18 , pp. 3955-3968
    • Sancho, R.M.1    Law, B.M.2    Harvey, K.3
  • 55
    • 80054787664 scopus 로고    scopus 로고
    • What genetics tells us about the causes and mechanisms of Parkinson's disease
    • Corti O, Lesage S, Brice A. What genetics tells us about the causes and mechanisms of Parkinson's disease. Physiol Rev. 2011;91:1161-1218.
    • (2011) Physiol Rev. , vol.91 , pp. 1161-1218
    • Corti, O.1    Lesage, S.2    Brice, A.3
  • 56
    • 33646134826 scopus 로고    scopus 로고
    • Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
    • Banziger C, Soldini D, Schutt C, Zipperlen P, Hausmann G, Basler K. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell. 2006;125:509-522.
    • (2006) Cell. , vol.125 , pp. 509-522
    • Banziger, C.1    Soldini, D.2    Schutt, C.3    Zipperlen, P.4    Hausmann, G.5    Basler, K.6
  • 57
    • 33646123992 scopus 로고    scopus 로고
    • Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
    • Bartscherer K, Pelte N, Ingelfinger D, Boutros M. Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell. 2006;125:523-533.
    • (2006) Cell. , vol.125 , pp. 523-533
    • Bartscherer, K.1    Pelte, N.2    Ingelfinger, D.3    Boutros, M.4
  • 58
    • 37749040775 scopus 로고    scopus 로고
    • The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network
    • Belenkaya TY, Wu Y, Tang X, et al. The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network. Dev Cell. 2008;14:120-131.
    • (2008) Dev Cell. , vol.14 , pp. 120-131
    • Belenkaya, T.Y.1    Wu, Y.2    Tang, X.3
  • 59
    • 38849106101 scopus 로고    scopus 로고
    • Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex
    • Franch-Marro X, Wendler F, Guidato S, et al. Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat Cell Biol. 2008;10:170-177.
    • (2008) Nat Cell Biol. , vol.10 , pp. 170-177
    • Franch-Marro, X.1    Wendler, F.2    Guidato, S.3
  • 60
    • 38849134055 scopus 로고    scopus 로고
    • Wingless secretion promotes and requires retromer-dependent cycling of Wntless
    • Port F, Kuster M, Herr P, et al. Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nat Cell Biol. 2008;10:178-185.
    • (2008) Nat Cell Biol. , vol.10 , pp. 178-185
    • Port, F.1    Kuster, M.2    Herr, P.3
  • 62
    • 67449123256 scopus 로고    scopus 로고
    • Brain iron homeostasis and neurodegenerative disease
    • Benarroch EE. Brain iron homeostasis and neurodegenerative disease. Neurology. 2009;72:1436-1440.
    • (2009) Neurology. , vol.72 , pp. 1436-1440
    • Benarroch, E.E.1
  • 63
    • 84858157347 scopus 로고    scopus 로고
    • Iron dysregulation in movement disorders
    • Dusek P, Jankovic J, Le W. Iron dysregulation in movement disorders. Neurobiol Dis. 2012;46:1-18.
    • (2012) Neurobiol Dis. , vol.46 , pp. 1-18
    • Dusek, P.1    Jankovic, J.2    Le, W.3
  • 64
    • 77949261597 scopus 로고    scopus 로고
    • Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent
    • Jiang H, Song N, Xu H, Zhang S, Wang J, Xie J. Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent. Cell Res. 2010;20:345-356.
    • (2010) Cell Res. , vol.20 , pp. 345-356
    • Jiang, H.1    Song, N.2    Xu, H.3    Zhang, S.4    Wang, J.5    Xie, J.6
  • 65
    • 57449092273 scopus 로고    scopus 로고
    • Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease
    • Salazar J, Mena N, Hunot S, et al. Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease. Proc Natl Acad Sci USA. 2008;105:18578-18583.
    • (2008) Proc Natl Acad Sci USA. , vol.105 , pp. 18578-18583
    • Salazar, J.1    Mena, N.2    Hunot, S.3
  • 66
    • 67650474704 scopus 로고    scopus 로고
    • Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells
    • Zhang S, Wang J, Song N, Xie J, Jiang H. Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells. Neurobiol Aging. 2009;30:1466-1476.
    • (2009) Neurobiol Aging. , vol.30 , pp. 1466-1476
    • Zhang, S.1    Wang, J.2    Song, N.3    Xie, J.4    Jiang, H.5
  • 67
    • 79961207947 scopus 로고    scopus 로고
    • DMT1 polymorphism and risk of Parkinson's disease
    • He Q, Du T, Yu X, et al. DMT1 polymorphism and risk of Parkinson's disease. Neurosci Lett. 2011;501:128-131.
    • (2011) Neurosci Lett. , vol.501 , pp. 128-131
    • He, Q.1    Du, T.2    Yu, X.3
  • 68
    • 80052989037 scopus 로고    scopus 로고
    • Enhanced autophagy from chronic toxicity of iron and mutant A53T alpha-synuclein: implications for neuronal cell death in Parkinson disease
    • Chew KC, Ang ET, Tai YK, et al. Enhanced autophagy from chronic toxicity of iron and mutant A53T alpha-synuclein: implications for neuronal cell death in Parkinson disease. J Biol Chem. 2011;286:33380-33389.
    • (2011) J Biol Chem. , vol.286 , pp. 33380-33389
    • Chew, K.C.1    Ang, E.T.2    Tai, Y.K.3
  • 69
    • 77958449984 scopus 로고    scopus 로고
    • alpha-Synuclein: membrane interactions and toxicity in Parkinson's disease
    • Auluck PK, Caraveo G, Lindquist S. alpha-Synuclein: membrane interactions and toxicity in Parkinson's disease. Annu Rev Cell Dev Biol. 2010;26:211-233.
    • (2010) Annu Rev Cell Dev Biol. , vol.26 , pp. 211-233
    • Auluck, P.K.1    Caraveo, G.2    Lindquist, S.3
  • 70
    • 77949729459 scopus 로고    scopus 로고
    • Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1
    • Roth JA, Singleton S, Feng J, Garrick M, Paradkar PN. Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1. J Neurochem. 2010;113:454-464.
    • (2010) J Neurochem. , vol.113 , pp. 454-464
    • Roth, J.A.1    Singleton, S.2    Feng, J.3    Garrick, M.4    Paradkar, P.N.5
  • 71
    • 77149155327 scopus 로고    scopus 로고
    • Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1
    • Tabuchi M, Yanatori I, Kawai Y, Kishi F. Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1. J Cell Sci. 2010;123:756-766.
    • (2010) J Cell Sci. , vol.123 , pp. 756-766
    • Tabuchi, M.1    Yanatori, I.2    Kawai, Y.3    Kishi, F.4
  • 72
    • 63149090431 scopus 로고    scopus 로고
    • Parkinson's disease: from monogenic forms to genetic susceptibility factors
    • Lesage S, Brice A. Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum Mol Genet. 2009;18:R48-R59.
    • (2009) Hum Mol Genet. , vol.18
    • Lesage, S.1    Brice, A.2
  • 73
    • 83455225173 scopus 로고    scopus 로고
    • Synaptic vesicle trafficking and Parkinson's disease
    • Esposito G, Ana Clara F, Verstreken P. Synaptic vesicle trafficking and Parkinson's disease. Dev Neurobiol. 2012;72:134-144.
    • (2012) Dev Neurobiol. , vol.72 , pp. 134-144
    • Esposito, G.1    Ana Clara, F.2    Verstreken, P.3
  • 74
    • 84866610524 scopus 로고    scopus 로고
    • Lysosome-dependent pathways as a unifying theme in Parkinson's disease
    • Tofaris GK. Lysosome-dependent pathways as a unifying theme in Parkinson's disease. Mov Disord. 2012;27:1364-1369.
    • (2012) Mov Disord. , vol.27 , pp. 1364-1369
    • Tofaris, G.K.1
  • 75
    • 33947521050 scopus 로고    scopus 로고
    • Helping Wingless take flight: how WNT proteins are secreted
    • Hausmann G, Banziger C, Basler K. Helping Wingless take flight: how WNT proteins are secreted. Nat Rev Mol Cell Biol. 2007;8:331-336.
    • (2007) Nat Rev Mol Cell Biol. , vol.8 , pp. 331-336
    • Hausmann, G.1    Banziger, C.2    Basler, K.3


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