Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength after Chronic Stress by Negative Modulators of Alpha5-Containing GABA A Receptors

Neuropsychopharmacology

Volumn 40, Issue 11, 2015, Pages 2499-2509

  Fischell, Jonathan ^a   Van Dyke, Adam M ^a   Kvarta, Mark D ^a   Legates, Tara A ^a   Thompson, Scott M ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA5; AMINO ACID RECEPTOR STIMULATING AGENT; AMPA RECEPTOR; ANTIDEPRESSANT AGENT; KETAMINE; L 655708; MRK 016; SUCROSE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; GABRA5 PROTEIN, RAT; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1; IMIDAZOLE DERIVATIVE; ISOXAZOLE DERIVATIVE; L 655,708; SUGAR INTAKE; TRIAZINE DERIVATIVE;

ALLOSTERISM; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; CHRONIC STRESS; CHRONIC UNPREDICTABLE STRESS; CONTROLLED STUDY; DOWN REGULATION; ELECTROENCEPHALOGRAM; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; MALE; NONHUMAN; OPEN FIELD BEHAVIOR; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SOCIAL INTERACTION TEST; SUCROSE PREFERENCE TEST; SYNAPSE; SYNAPTIC TRANSMISSION; WESTERN BLOTTING; ADMINISTRATION AND DOSAGE; ANIMAL; CHRONIC DISEASE; DISEASE MODEL; DRUG EFFECTS; DRUG THERAPY; EXERCISE; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; HIPPOCAMPAL CA1 REGION; MENTAL STRESS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION; SOCIAL BEHAVIOR; SPRAGUE DAWLEY RAT; SUGAR INTAKE; TISSUE CULTURE TECHNIQUE;

ANIMALS; ANTIDEPRESSIVE AGENTS; CA1 REGION, HIPPOCAMPAL; CHRONIC DISEASE; DIETARY SUCROSE; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; GABA MODULATORS; IMIDAZOLES; ISOXAZOLES; MALE; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, GABA-A; RESTRAINT, PHYSICAL; SOCIAL BEHAVIOR; STRESS, PSYCHOLOGICAL; SYNAPSES; SYNAPTIC TRANSMISSION; TISSUE CULTURE TECHNIQUES; TRIAZINES;

EID: 84941315564     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2015.112     Document Type: Article

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