Synaptic potentiation is critical for rapid antidepressant response to ketamine in treatment-resistant major depression

Biological Psychiatry

Volumn 72, Issue 7, 2012, Pages 555-561

  Cornwell, Brian R ^a   Salvadore, Giacomo ^a,b   Furey, Maura ^a   Marquardt, Craig A ^a   Brutsche, Nancy E ^a   Grillon, Christian ^a   Zarate Jr , Carlos A ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b JOHNSON AND JOHNSON   (United States)

Author keywords

oscillation; Cortical excitability; ketamine; magnetoencephalography; major depression; NMDA antagonist

Indexed keywords

KETAMINE; RILUZOLE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EVOKED SOMATOSENSORY RESPONSE; FEMALE; HUMAN; LONG TERM POTENTIATION; MAGNETOENCEPHALOGRAPHY; MAJOR DEPRESSION; MALE; NERVE CELL PLASTICITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TACTILE STIMULATION; TREATMENT RESPONSE;

ADULT; ANALYSIS OF VARIANCE; ANTIDEPRESSIVE AGENTS; BRAIN MAPPING; CEREBRAL CORTEX; DEPRESSIVE DISORDER, MAJOR; DEPRESSIVE DISORDER, TREATMENT-RESISTANT; ELECTRIC STIMULATION; FEMALE; FINGERS; FUNCTIONAL LATERALITY; HUMANS; KETAMINE; MAGNETOENCEPHALOGRAPHY; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; REACTION TIME; SYNAPTIC POTENTIALS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84866034125     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.03.029     Document Type: Article

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