Cyclin Y is involved in the regulation of adipogenesis and lipid production

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  An, Weiwei ^a   Zhang, Zhuzhen ^a   Zeng, Liyong ^a   Yang, Ying ^a   Zhu, Xueliang ^a   Wu, Jiarui ^a,b,c  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b SHANGHAI ADVANCED RESEARCH INSTITUTE   (China)

^c SHANGHAITECH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CYCLIN Y; CYCLINE; FATTY ACID SYNTHASE; INSULIN; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, MOUSE; CYCLIN Y, MOUSE;

ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BROWN ADIPOSE TISSUE; CALORIC RESTRICTION; CELL DIFFERENTIATION; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; FAT CONTENT; FEMALE; HEPG2 CELL LINE; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPOGENESIS; LIVER CELL; MALE; MOUSE; MUSCLE; NONHUMAN; OBESITY; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STRESS; UPREGULATION; WHITE ADIPOCYTE; WHITE ADIPOSE TISSUE; ADIPOCYTE; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HEP-G2 CELL LINE; HUMAN; KNOCKOUT MOUSE; LIPID METABOLISM; METABOLISM; THERMOGENESIS;

ADIPOCYTES; ADIPOGENESIS; ANIMALS; CALORIC RESTRICTION; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; CYCLINS; DIET, HIGH-FAT; GENE EXPRESSION REGULATION; HEP G2 CELLS; HUMANS; INSULIN; LIPID METABOLISM; LIPIDS; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; THERMOGENESIS; TRANSCRIPTION, GENETIC;

EID: 84941308752     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132721     Document Type: Article

References (41)

1. Stephane Gesta, Yu Hua Tseng, Kahn CR. Developmental origin of fat: tracking obesity to its source. Cell. 2007;131:242-256. PMID: 17956727
2. Guzzardi MA, Iozzo P. Fatty heart, cardiac damage, and inflammation. Rev Diabet Stud. 2011;8:403-417. doi: 10.1900/RDS.2011.8.403 PMID: 22262077
3. Muoio DM, Newgard CB. Obesity-related derangements in metabolic regulation. Annu Rev Biochem. 2006;75:367-401. PMID: 16756496
4. Petersen KF, Oral EA, Dufour S, Befroy D, Ariyan C, Yu C, et al. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest. 2002;109:1345-1350. PMID: 12021250
5. Taniguchi CM, Emanuelli B, Kahn CR. Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol. 2006;7:85-96. PMID: 16493415
6. Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest. 2002;109:1125-1131. PMID: 11994399
7. Shimano H, Yahagi N, Amemiya-Kudo M, Hasty AH, Osuga J-I, Tamura Y, et al. Sterol regulatory elementbinding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes. J Biol Chem. 1999;274:35832-35839. PMID: 10585467
8. Eberle D, Hegarty B, Bossard P, Ferre P, Foufelle F. SREBP transcription factors: master regulators of lipid homeostasis. Biochimie. 2004;86:839-848. PMID: 15589694
9. Kim JB, Spiegelman BM. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev. 1996;10:1096-1107. PMID: 8654925
10. Porstmann T, Griffiths B, Chung Y-L, Delpuech O, Griffiths JR, Downward J, et al. PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. Oncogene. 2005;24:6465-6481. PMID: 16007182
11. Noble ME, Endicott JA, Brown NR, Johnson LN. The cyclin box fold: protein recognition in cell-cycle and transcription control. Trends Biochem Sci. 1997;22:482-487. PMID: 9433129
12. Li X, Wang X, Liu G, Li R, Yu L. Identification and characterization of cyclin X which activates transcriptional activities of c-Myc. Mol Biol Rep. 2009;36:97-103. PMID: 18060517
13. Liu D, Guest S, Finley RL. Why Cyclin Y? A highly conserved cyclin with essential functions. Fly. 2010;4:278-282. PMID: 20699655
14. Jiang M, Gao Y, Yang T, Zhu X, Chen J. Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1. FEBS Lett. 2009;583:2171-2178. doi: 10.1016/j.febslet.2009.06.010 PMID: 19524571
15. Liu D, Finley RL. Cyclin Y is a novel conserved cyclin essential for development in Drosophila. Genetics. 2010;184:1025-1035. doi: 10.1534/genetics.110.114017 PMID: 20100936
16. Mikolcevic P, Sigl R, Rauch V, Hess MW, Pfaller K, Barisic M, et al. Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis. Mol Cell Biol. 2012;32:868-879. doi: 10.1128/MCB.06261-11 PMID: 22184064
17. Park M, Watanabe S, Poon VVN, Ou CY, Jorgensen EM, Shen K. CYY-1/cyclin Y and CDK-5 differentially regulate synapse elimination and formation for rewiring neural circuits. Neuron. 2011;70:742-757. doi: 10.1016/j.neuron. 2011.04.002 PMID: 21609829
18. Yang L, Zhang Y, Wang L, Fan F, Zhu L, Li Z, et al. Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22. J Hepatol. 2010;53:339-347. doi: 10.1016/j.jhep. 2010.03.004 PMID: 20452699
19. Pei H, Yao Y, Yang Y, Liao K, Wu J. Kruppel-like factor KLF9 regulates PPARα transactivation at the middle stage of adipogenesis. Cell Death Differ. 2011;18:315-327. doi: 10.1038/cdd.2010.100 PMID: 20725087
20. Speakman JR, Hambly C. Starving for life: what animal studies can and cannot tell us about the use of caloric restriction to prolong human lifespan. J Nutr. 2007;137:1078-1086. PMID: 17374682
21. Green H, Meuth M. An established pre-adipose cell line and its differentiation in culture. Cell. 1974;3:127-133. PMID: 4426090
22. Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol. 2006;7:885-896. PMID: 17139329
23. Lu M, Wan M, Leavens KF, Chu Q, Monks BR, Fernandez S, et al. Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1. Nat Med. 2012;18:388-395. doi: 10.1038/nm.2686 PMID: 22344295
24. Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, et al. Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/Ζ. Cell Metab. 2006;3:343-353. PMID: 16679292
25. Kohn AD, Summers SA, Birnbaum MJ, Roth RA. Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J Biol Chem. 1996;271:31372-31378. PMID: 8940145
26. Lin S, Boey D, and Herzog H. NPY and Y receptors: lessons from transgenic and knockout models. Neuropeptides. 2004;38:189-200. PMID: 15337371
27. Chao PT, Yang L, Aja S, Moran TH, and Bi S. Knockdown of NPY expression in the dorsomedial hypothalamus promotes development of brown adipocytes and prevents diet-induced obesity. Cell Metab. 2011;13:573-583. doi: 10.1016/j.cmet.2011.02.019 PMID: 21531339
28. Shi YC, Lau J, Lin Z, Zhang H, Zhai L, Sperk G, et al. Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN. Cell Metab. 2013;17:236-248. doi: 10.1016/j.cmet.2013.01.006 PMID: 23395170
29. Hermann GE, Barnes MJ, Rogers RC. Leptin and thyrotropin-releasing hormone: cooperative action in the hindbrain to activate brown adipose thermogenesis. Brain Res. 2006;1117:118-124. PMID: 16956588
30. Van Den Beukel JC, Grefhorst A. Interactions between the gut, the brain and brown adipose tissue function. Front Hom Res. 2014;42:107-122.
31. Ootsuka Y, De Menezes RC, Zaretsky DV, Alimoradian A, Hunt J, Stefanidis A, et al. Brown adipose tissue thermogenesis heats brain and body as part of the brain coordinated ultradian basic rest-activity cycle. Neuroscience. 2009;164:849-861. doi: 10.1016/j.neuroscience.2009.08.013 PMID: 19679172
32. Blessing W, Mohammed M, Ootsuka Y. Heating and eating: brown adipose tissue thermogenesis precedes food ingestion as part of the ultradian basic rest-activity cycle in rats. Physiol Behav. 2012;105:966-974. doi: 10.1016/j.physbeh.2011.11.009 PMID: 22115948
33. Tang QQ, Otto TC, Lane MD. Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc Natl Acad Sci USA. 2003;100:44-49. PMID: 12502791
34. Fu M, Rao M, Bouras T, Wang C, Wu K, Zhang X, et al. Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment. J Biol Chem. 2005;280:16934-16941. PMID: 15713663
35. Davidson G, Shen J, Huang YL, Su Y, Karaulanov E, Bartscherer K, et al. Cell cycle control of wnt receptor activation. Dev Cell. 2009;17:788-799. doi: 10.1016/j.devcel.2009.11.006 PMID: 20059949
36. Ross SE, Hemati N, Longo KA, Bennett CN, Lucas PC, Erickson RL, et al. Inhibition of adipogenesis by Wnt signaling. Science. 2000;289:950-953. PMID: 10937998
37. Kennell JA, MacDougald OA. Wnt signaling inhibits adipogenesis through β-catenin-dependent and independent mechanisms. J Biol Chem. 2005;280:24004-24010. PMID: 15849360
38. Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature. 2001;414:799-806. PMID: 11742412
39. Amemiya KM, Shimano H, Hasty AH, Yahagi N, Yoshikawa T, Matsuzaka T, et al. Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes. J Lipid Res. 2002;43:1220-1235. PMID: 12177166
40. Shimomura I, Bashmakov Y, Ikemoto S, Horton JD, Brown MS, Goldstein JL. Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes. Proc Natl Acad Sci USA. 1999;96:13656-13661. PMID: 10570128
41. Bengoechea-Alonso MT, Ericsson J. A phosphorylation cascade controls the degradation of active SREBP1. J Biol Chem. 2009;284:5885-5895. doi: 10.1074/jbc. M807906200 PMID: 19126544