Leptin and thyrotropin-releasing hormone: Cooperative action in the hindbrain to activate brown adipose thermogenesis

Brain Research

Volumn 1117, Issue 1, 2006, Pages 118-124

  Hermann, Gerlinda E ^a   Barnes, Maria J ^a   Rogers, Richard C ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

Solitary nucleus; Sympathetic; Temperature

Indexed keywords

LEPTIN; PROTIRELIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; CORE TEMPERATURE; DECEREBRATION; FEMALE; HORMONE ACTION; MALE; MEDULLA OBLONGATA; NONHUMAN; PRIORITY JOURNAL; RAT; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; THERMOGENESIS; THERMOREGULATION;

ADIPOSE TISSUE, BROWN; ANIMALS; DRUG INTERACTIONS; EFFERENT PATHWAYS; FEMALE; LEPTIN; MALE; NEURAL PATHWAYS; RAPHE NUCLEI; RATS; RATS, LONG-EVANS; RHOMBENCEPHALON; THERMOGENESIS; THYROTROPIN-RELEASING HORMONE;

EID: 33749985751     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.08.018     Document Type: Article

References (36)

1. Arancibia S., Rage F., Astier H., and Tapia-Arancibia L. Neuroendocrine and autonomous mechanisms underlying thermoregulation in cold environment. Neuroendocrinology 64 (1996) 257-267
2. Bamshad M., Song C.K., and Bartness T.J. CNS origins of the sympathetic nervous system outflow to brown adipose tissue. Am. J. Physiol. 276 (1999) R1569-R1578
3. Blessing W.W. Arterial Pressure and Blood Flow to the Tissues. The Lower Brainstem and Bodily Homeostasis (1997), Oxford University Press, New York 165-268
4. Blumberg M.S., Deaver K., and Kirby R.F. Leptin disinhibits nonshivering thermogenesis in infants after maternal separation. Am. J. Physiol. 276 (1999) R606-R610
5. Boulant J.A. Role of the preoptic-anterior hypothalamus in thermoregulation and fever. Clin. Infect. Dis. 31 Suppl 5 (2000) S157-S161
6. Broadwell R.D., and Sofroniew M.V. Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system. Exp. Neurol. 120 (1993) 245-263
7. Buelke-Sam J., Holson J.F., Bazare J.J., and Young J.F. Comparative stability of physiological parameters during sustained anesthesia in rats. Lab. Anim. Sci. 28 (1978) 157-162
8. Cano G., Passerin A.M., Schiltz J.C., Card J.P., Morrison S.F., and Sved A.F. Anatomical substrates for the central control of sympathetic outflow to interscapular adipose tissue during cold exposure. J. Comp. Neurol. 460 (2003) 303-326
9. Carlisle H.J., Dubuc P.U., and Stock M.J. Effects of beta-adrenoceptor agonists and antagonists on thermoregulation in the cold in lean and obese Zucker rats. Pharmacol. Biochem. Behav. 46 (1993) 953-958
10. Commins S.P., Marsh D.J., Thomas S.A., Watson P.M., Padgett M.A., Palmiter R., and Gettys T.W. Norepinephrine is required for leptin effects on gene expression in brown and white adipose tissue. Endocrinology 140 (1999) 1214-1222
11. Cusin I., Rohner-Jeanrenaud F., Stricker-Krongrad A., and Jeanrenaud B. The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats. Reduced sensitivity compared with lean animals. Diabetes 45 (1996) 1446-1450
12. Dekin M.S., Richerson G.B., and Getting P.A. Thyrotropin-releasing hormone induces rhythmic bursting in neurons of the nucleus tractus solitarius. Science 229 (1985) 67-69
13. DiRocco R.J., and Grill H.J. The forebrain is not essential for sympathoadrenal hyperglycemic response to glucoprivation. Science 204 (1979) 1112-1114
14. Elmquist J.K. Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin. Int. J. Obes. Relat. Metab. Disord. 25 Suppl 5 (2001) S78-S82
15. Eskay R.L., Long R.T., and Palkovits M. Localization of immunoreactive thyrotropin releasing hormone in the lower brainstem of the rat. Brain Res. 277 (1983) 159-162
16. Geiser F., Kortner G., and Schmidt I. Leptin increases energy expenditure of a marsupial by inhibition of daily torpor. Am. J. Physiol. 275 (1998) R1627-R1632
17. Grill H.J., and Kaplan J.M. The neuroanatomical axis for control of energy balance. Front Neuroendocrinol. 23 (2002) 2-40
18. Gross P.M., Wall K.M., Wainman D.S., and Shaver S.W. Subregional topography of capillaries in the dorsal vagal complex of rats: II. Physiological properties. J. Comp. Neurol. 306 (1991) 83-94
19. Harris R.B., Kelso E.W., Flatt W.P., Bartness T.J., and Grill H.J. Energy expenditure and body composition of chronically maintained decerebrate rats in the fed and fasted condition. Endocrinology 147 (2006) 1365-1376
20. Hermann G., and Rogers R.C. Tumor necrosis factor-alpha in the dorsal vagal complex suppresses gastric motility. Neuroimmunomodulation 2 (1995) 74-81
21. Hermann G.E., Holmes G.M., and Rogers R.C. TNF(alpha) modulation of visceral and spinal sensory processing. Curr. Pharm. Des. 11 (2005) 1391-1409
22. I'Anson H., Sundling L.A., Roland S.M., and Ritter S. Immunotoxic destruction of distinct catecholaminergic neuron populations disrupts the reproductive response to glucoprivation in female rats. Endocrinology 144 (2003) 4325-4331
23. Li Y.W., and Bayliss D.A. Presynaptic inhibition by 5-HT1B receptors of glutamatergic synaptic inputs onto serotonergic caudal raphe neurones in rat. J. Physiol. 510 Pt. 1 (1998) 121-134
24. Lynn R.B., Kreider M.S., and Miselis R.R. Thyrotropin-releasing hormone-immunoreactive projections to the dorsal motor nucleus and the nucleus of the solitary tract of the rat. J. Comp. Neurol. 311 (1991) 271-288
25. Madden C.J., and Morrison S.F. Excitatory amino acid receptors in the dorsomedial hypothalamus mediate prostaglandin-evoked thermogenesis in brown adipose tissue. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286 (2004) R320-R325
26. Martinez V., Wang L., and Tache Y. Central TRH receptor 1 antisense blocks cold-induced gastric emptying but not brain c-Fos induction. Peptides 22 (2001) 81-90
27. McCann M.J., Hermann G.E., and Rogers R.C. Thyrotropin-releasing hormone: effects on identified neurons of the dorsal vagal complex. J. Auton. Nerv. Syst. 26 (1989) 107-112
28. Morrison S.F. Activation of 5-HT1A receptors in raphe pallidus inhibits leptin-evoked increases in brown adipose tissue thermogenesis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286 (2004) R832-R837
29. Morrison S.F., Sved A.F., and Passerin A.M. GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue. Am. J. Physiol. 276 (1999) R290-R297
30. Nelson R.J. Leptin: the "skinny" on torpor. Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 (2004) R6-R7
31. Palkovits M., Mezey E., Eskay R.L., and Brownstein M.J. Innervation of the nucleus of the solitary tract and the dorsal vagal nucleus by thyrotropin-releasing hormone-containing raphe neurons. Brain Res. 373 (1986) 246-251
32. Peters J.H., Karpiel A.B., Ritter R.C., and Simasko S.M. Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin. Endocrinology 145 (2004) 3652-3657
33. Rogers R.C., McTigue D.M., and Hermann G.E. Vagal control of digestion: modulation by central neural and peripheral endocrine factors. Neurosci. Biobehav. Rev. 20 (1996) 57-66
34. Sasek C.A., Wessendorf M.W., and Helke C.J. Evidence for co-existence of thyrotropin-releasing hormone, substance P and serotonin in ventral medullary neurons that project to the intermediolateral cell column in the rat. Neuroscience 35 (1990) 105-119
35. Schneider J.E., and Zhou D. Interactive effects of central leptin and peripheral fuel oxidation on estrous cyclicity. Am. J. Physiol. 277 (1999) R1020-R1024
36. Schwartz G.J., and Moran T.H. Leptin and neuropeptide y have opposing modulatory effects on nucleus of the solitary tract neurophysiological responses to gastric loads: implications for the control of food intake. Endocrinology 143 (2002) 3779-3784