Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake

Journal of Biological Chemistry

Volumn 290, Issue 36, 2015, Pages 21788-21799

  Yang, Xiaoxiao ^a,b   Yao, Hui ^a,b   Chen, Yuanli ^a,c,d   Sun, Lei ^b   Li, Yan ^b   Ma, Xingzhe ^b   Duan, Shengzhong ^e   Li, Xiaoju ^b   Xiang, Rong ^a,c   Han, Jihong ^a,b,d   Duan, Yajun ^a,b,d  

^a State Key Laboratory of Medicinal Chemical Biology   (China)

^b Institute of Biomedical Sciences   (China)

^c Colleges of Medicine ^*  (India)

^d NANKAI UNIVERSITY   (China)

^e Chinese Academy of Sciences   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; MACROPHAGES;

ANTIOXIDANT SYSTEMS; GLUTATHIONES; LIPID ACCUMULATIONS; OXIDIZED LOW-DENSITY LIPOPROTEINS (OXLDL); PROTEIN EXPRESSIONS; TRANSLATIONAL EFFICIENCIES;

ENZYME INHIBITION;

ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; CATALASE; CD36 ANTIGEN; GLUTATHIONE; GLUTATHIONE DISULFIDE; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; ANTIMETABOLITE; LOW DENSITY LIPOPROTEIN; SCAVENGER;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; IN VIVO STUDY; KIDNEY; LIPID STORAGE; LIPOPROTEIN METABOLISM; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; REGULATORY MECHANISM; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; ANTIGENS, CD36; ANTIMETABOLITES; BLOTTING, WESTERN; BUTHIONINE SULFOXIMINE; CELL LINE; FREE RADICAL SCAVENGERS; GENE EXPRESSION; GLUTATHIONE; GLUTATHIONE DISULFIDE; LIPOPROTEINS, LDL; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; PPAR GAMMA; PROTEIN BIOSYNTHESIS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 84941299656     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.654582     Document Type: Article

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