-
1
-
-
32944463899
-
Angiogenesis
-
Folkman J. Angiogenesis. Annu Rev Med 2006; 57:1-18.
-
(2006)
Annu Rev Med
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
2
-
-
0026525407
-
Interferon alfa-2a therapy for life-threatening hemangiomas of infancy
-
Ezekowitz RA, Mulliken JB, Folkman J. Interferon alfa-2a therapy for life-threatening hemangiomas of infancy. N Engl J Med 1992;326:1456-1463.
-
(1992)
N Engl J Med
, vol.326
, pp. 1456-1463
-
-
Ezekowitz, R.A.1
Mulliken, J.B.2
Folkman, J.3
-
3
-
-
33947732977
-
Angiogenesis: An organizing principle for drug discovery?
-
Folkman J. Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 2007;6: 273-286.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 273-286
-
-
Folkman, J.1
-
4
-
-
61649113720
-
Endogenous inhibitors of angiogenesis: A historical review
-
Ribatti D. Endogenous inhibitors of angiogenesis: a historical review. Leuk Res 2009;33:638-644.
-
(2009)
Leuk Res
, vol.33
, pp. 638-644
-
-
Ribatti, D.1
-
5
-
-
0027970092
-
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
-
O'Reilly MS, Holmgren L, Shing Y, et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994;79:315-328.
-
(1994)
Cell
, vol.79
, pp. 315-328
-
-
O'Reilly, M.S.1
Holmgren, L.2
Shing, Y.3
-
6
-
-
0141678926
-
Recombinant human angiostatin by twicedaily subcutaneous injection in advanced cancer: A pharmacokinetic and long-term safety study
-
Beerepoot LV, Witteveen EO, Groenewegen G, et al. Recombinant human angiostatin by twicedaily subcutaneous injection in advanced cancer: a pharmacokinetic and long-term safety study. Clin Cancer Res 2003;9:4025-4033.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4025-4033
-
-
Beerepoot, L.V.1
Witteveen, E.O.2
Groenewegen, G.3
-
7
-
-
29844452745
-
Recombinant human angiostatin (rhAngiostatin) in combination with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer: A phase II study from Indiana University
-
Kurup A, Lin C, Murry DJ, et al. Recombinant human angiostatin (rhAngiostatin) in combination with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer: a phase II study from Indiana University. Ann Oncol 2006;17: 97-103.
-
(2006)
Ann Oncol
, vol.17
, pp. 97-103
-
-
Kurup, A.1
Lin, C.2
Murry, D.J.3
-
8
-
-
70449556825
-
The antitumorigenic trifecta
-
Mowery YM, Pizzo SV. The antitumorigenic trifecta. Blood 2009;114:1727-1728.
-
(2009)
Blood
, vol.114
, pp. 1727-1728
-
-
Mowery, Y.M.1
Pizzo, S.V.2
-
9
-
-
40949129489
-
Linking antibody Fc domain to endostatin significantly improves endostatin half-life and efficacy
-
Lee TY, Tjin Tham Sjin RM, Movahedi S, et al. Linking antibody Fc domain to endostatin significantly improves endostatin half-life and efficacy. Clin Cancer Res 2008;14:1487-1493.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1487-1493
-
-
Lee, T.Y.1
Tjin Tham Sjin, R.M.2
Movahedi, S.3
-
10
-
-
0032031748
-
Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases
-
Cao Y, O'Reilly MS, Marshall B, et al. Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases. J Clin Invest 1998;101:1055-1063.
-
(1998)
J Clin Invest
, vol.101
, pp. 1055-1063
-
-
Cao, Y.1
O'Reilly, M.S.2
Marshall, B.3
-
11
-
-
43749084192
-
Mutation of human plasminogen kringle 1-5 enhances antiangiogenic action via increased interaction with integrin avb3
-
Chang PC, Chang YJ, Wu HL, et al. Mutation of human plasminogen kringle 1-5 enhances antiangiogenic action via increased interaction with integrin avb3. Thromb Haemost 2008;99:729-738.
-
(2008)
Thromb Haemost
, vol.99
, pp. 729-738
-
-
Chang, P.C.1
Chang, Y.J.2
Wu, H.L.3
-
12
-
-
73849115332
-
Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid
-
Jullienne B, Vigant F, Muth E, et al. Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid. Gene Ther 2009;16:1405-1415.
-
(2009)
Gene Ther
, vol.16
, pp. 1405-1415
-
-
Jullienne, B.1
Vigant, F.2
Muth, E.3
-
13
-
-
70349248380
-
Angiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteins
-
Lee TY, Muschal S, Pravda EA, et al. Angiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteins. Blood 2009;114:1987-1998.
-
(2009)
Blood
, vol.114
, pp. 1987-1998
-
-
Lee, T.Y.1
Muschal, S.2
Pravda, E.A.3
-
14
-
-
84864871735
-
Development of the hybrid Sleeping Beauty: Baculovirus vector for sustained gene expression and cancer therapy
-
Luo WY, Shih YS, Hung CL, et al. Development of the hybrid Sleeping Beauty: baculovirus vector for sustained gene expression and cancer therapy. Gene Ther 2012;19:844-851.
-
(2012)
Gene Ther
, vol.19
, pp. 844-851
-
-
Luo, W.Y.1
Shih, Y.S.2
Hung, C.L.3
-
15
-
-
1642342770
-
Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: Long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor
-
Ponnazhagan S, Mahendra G, Kumar S, et al. Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor. Cancer Res 2004; 64:1781-1787.
-
(2004)
Cancer Res
, vol.64
, pp. 1781-1787
-
-
Ponnazhagan, S.1
Mahendra, G.2
Kumar, S.3
-
16
-
-
33750046350
-
Liposome-mediated gene transfer of K1-5 suppresses tumor development and improves the prognosis of hepatocellular carcinoma in mice
-
Torimura T, Ueno T, Sata M. Liposome-mediated gene transfer of K1-5 suppresses tumor development and improves the prognosis of hepatocellular carcinoma in mice. Med Mol Morphol 2006;39:72-78.
-
(2006)
Med Mol Morphol
, vol.39
, pp. 72-78
-
-
Torimura, T.1
Ueno, T.2
Sata, M.3
-
17
-
-
0033545930
-
Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis
-
Cao R, Wu HL, Veitonmaki N, et al. Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis. Proc Natl Acad Sci USA 1999;96: 5728-5733.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5728-5733
-
-
Cao, R.1
Wu, H.L.2
Veitonmaki, N.3
-
18
-
-
79954650563
-
State-of-the-art gene-based therapies: The road ahead
-
Kay MA. State-of-the-art gene-based therapies: the road ahead. Nat Rev Genet 2011;12:316-328.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 316-328
-
-
Kay, M.A.1
-
19
-
-
77950961700
-
Future prospects and challenges of antiangiogenic cancer gene therapy
-
Samaranayake H, Maatta AM, Pikkarainen J, et al. Future prospects and challenges of antiangiogenic cancer gene therapy. Hum Gene Ther 2010;21:381-396.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 381-396
-
-
Samaranayake, H.1
Maatta, A.M.2
Pikkarainen, J.3
-
20
-
-
77953251302
-
Viral vectors for gene transfer: Current status of gene therapeutics
-
Heilbronn R, Weger S. Viral vectors for gene transfer: current status of gene therapeutics. Handb Exp Pharmacol 2010;197:143-170.
-
(2010)
Handb Exp Pharmacol
, vol.197
, pp. 143-170
-
-
Heilbronn, R.1
Weger, S.2
-
21
-
-
84863011918
-
The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis y antigen
-
Kuo CH, Chen PK, Chang BI, et al. The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis Y antigen. Blood 2012;119:1302-1313.
-
(2012)
Blood
, vol.119
, pp. 1302-1313
-
-
Kuo, C.H.1
Chen, P.K.2
Chang, B.I.3
-
22
-
-
2642642141
-
Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
-
Xiao X, Li J, Samulski RJ. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J Virol 1998;72: 2224-2232.
-
(1998)
J Virol
, vol.72
, pp. 2224-2232
-
-
Xiao, X.1
Li, J.2
Samulski, R.J.3
-
23
-
-
79953244361
-
Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis
-
Ebos JM, Kerbel RS. Antiangiogenic therapy: impact on invasion, disease progression, and metastasis. Nat Rev Clin Oncol 2011;8:210-221.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 210-221
-
-
Ebos, J.M.1
Kerbel, R.S.2
-
24
-
-
84880289352
-
A largely random AAV integration profile after LPLD gene therapy
-
Kaeppel C, Beattie SG, Fronza R, et al. A largely random AAV integration profile after LPLD gene therapy. Nat Med 2013;19:889-891.
-
(2013)
Nat Med
, vol.19
, pp. 889-891
-
-
Kaeppel, C.1
Beattie, S.G.2
Fronza, R.3
-
25
-
-
38449089618
-
Cancer gene therapy using adeno-associated virus vectors
-
Park K, Kim WJ, Cho YH, et al. Cancer gene therapy using adeno-associated virus vectors. Front Biosci 2008;13:2653-2659.
-
(2008)
Front Biosci
, vol.13
, pp. 2653-2659
-
-
Park, K.1
Kim, W.J.2
Cho, Y.H.3
-
26
-
-
79955597265
-
Longterm safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins
-
Nathwani AC, Rosales C, Mcintosh J, et al. Longterm safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins. Mol Ther 2011;19:876-885.
-
(2011)
Mol Ther
, vol.19
, pp. 876-885
-
-
Nathwani, A.C.1
Rosales, C.2
Mcintosh, J.3
-
27
-
-
84855161388
-
Adenovirus-associated virus vector-mediated gene transfer in hemophilia B
-
Nathwani AC, Tuddenham EG, Rangarajan S, et al. Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med 2011;365: 2357-2365.
-
(2011)
N Engl J Med
, vol.365
, pp. 2357-2365
-
-
Nathwani, A.C.1
Tuddenham, E.G.2
Rangarajan, S.3
-
28
-
-
79952258871
-
Recombinant adeno-associated virus type 2 pseudotypes: Comparing safety, specificity, and transduction efficiency in the primate striatum: Laboratory investigation
-
Sanchez CE, Tierney TS, Gale JT, et al. Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum: laboratory investigation. J Neurosurg 2011;114: 672-680.
-
(2011)
J Neurosurg
, vol.114
, pp. 672-680
-
-
Sanchez, C.E.1
Tierney, T.S.2
Gale, J.T.3
-
29
-
-
44049094771
-
Clinical gene therapy using recombinant adeno-associated virus vectors
-
Mueller C, Flotte TR. Clinical gene therapy using recombinant adeno-associated virus vectors. Gene Ther 2008;15:858-863.
-
(2008)
Gene Ther
, vol.15
, pp. 858-863
-
-
Mueller, C.1
Flotte, T.R.2
-
30
-
-
33644820684
-
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
-
Manno CS, Pierce GF, Arruda VR, et al. Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat Med 2006;12:342-347.
-
(2006)
Nat Med
, vol.12
, pp. 342-347
-
-
Manno, C.S.1
Pierce, G.F.2
Arruda, V.R.3
-
31
-
-
0037015049
-
Novel adenoassociated viruses from rhesus monkeys as vectors for human gene therapy
-
Gao GP, Alvira MR, Wang L, et al. Novel adenoassociated viruses from rhesus monkeys as vectors for human gene therapy. Proc Natl Acad Sci USA 2002;99:11854-11859.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11854-11859
-
-
Gao, G.P.1
Alvira, M.R.2
Wang, L.3
-
32
-
-
10644289281
-
Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice
-
Nakai H, Fuess S, Storm TA, et al. Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice. J Virol 2005;79: 214-224.
-
(2005)
J Virol
, vol.79
, pp. 214-224
-
-
Nakai, H.1
Fuess, S.2
Storm, T.A.3
-
33
-
-
79959972143
-
Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer
-
Vanrell L, Di Scala M, Blanco L, et al. Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer. Mol Ther 2011;19:1245-1253.
-
(2011)
Mol Ther
, vol.19
, pp. 1245-1253
-
-
Vanrell, L.1
Di Scala, M.2
Blanco, L.3
-
34
-
-
80053492356
-
Advancements in adeno-associated viral gene therapy approaches: Exploring a new horizon
-
Aalbers CJ, Tak PP, Vervoordeldonk MJ. Advancements in adeno-associated viral gene therapy approaches: exploring a new horizon. F1000 Med Rep 2011;3:17.
-
(2011)
F1000 Med Rep
, vol.3
, pp. 17
-
-
Aalbers, C.J.1
Tak, P.P.2
Vervoordeldonk, M.J.3
-
35
-
-
84871945466
-
Adeno-associated viral vectors for gene therapy of inherited retinal degenerations
-
Flannery JG, Visel M. Adeno-associated viral vectors for gene therapy of inherited retinal degenerations. Methods Mol Biol 2013;935:351-369.
-
(2013)
Methods Mol Biol
, vol.935
, pp. 351-369
-
-
Flannery, J.G.1
Visel, M.2
-
36
-
-
1142299564
-
Anti-tumor efficacy of human angiostatin using liver-mediated adeno-associated virus gene therapy
-
Lalani AS, Chang B, Lin J, et al. Anti-tumor efficacy of human angiostatin using liver-mediated adeno-associated virus gene therapy. Mol Ther 2004;9:56-66.
-
(2004)
Mol Ther
, vol.9
, pp. 56-66
-
-
Lalani, A.S.1
Chang, B.2
Lin, J.3
|