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Volumn 26, Issue 9, 2015, Pages 603-613

Development of Recombinant Adeno-Associated Virus Serotype 2/8 Carrying Kringle Domains of Human Plasminogen for Sustained Expression and Cancer Therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOSTATIN; K15TM PROTEIN; PARVOVIRUS VECTOR; PLASMINOGEN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 84941270907     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2013.220     Document Type: Article
Times cited : (10)

References (36)
  • 1
    • 32944463899 scopus 로고    scopus 로고
    • Angiogenesis
    • Folkman J. Angiogenesis. Annu Rev Med 2006; 57:1-18.
    • (2006) Annu Rev Med , vol.57 , pp. 1-18
    • Folkman, J.1
  • 2
    • 0026525407 scopus 로고
    • Interferon alfa-2a therapy for life-threatening hemangiomas of infancy
    • Ezekowitz RA, Mulliken JB, Folkman J. Interferon alfa-2a therapy for life-threatening hemangiomas of infancy. N Engl J Med 1992;326:1456-1463.
    • (1992) N Engl J Med , vol.326 , pp. 1456-1463
    • Ezekowitz, R.A.1    Mulliken, J.B.2    Folkman, J.3
  • 3
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: An organizing principle for drug discovery?
    • Folkman J. Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 2007;6: 273-286.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 273-286
    • Folkman, J.1
  • 4
    • 61649113720 scopus 로고    scopus 로고
    • Endogenous inhibitors of angiogenesis: A historical review
    • Ribatti D. Endogenous inhibitors of angiogenesis: a historical review. Leuk Res 2009;33:638-644.
    • (2009) Leuk Res , vol.33 , pp. 638-644
    • Ribatti, D.1
  • 5
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly MS, Holmgren L, Shing Y, et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994;79:315-328.
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3
  • 6
    • 0141678926 scopus 로고    scopus 로고
    • Recombinant human angiostatin by twicedaily subcutaneous injection in advanced cancer: A pharmacokinetic and long-term safety study
    • Beerepoot LV, Witteveen EO, Groenewegen G, et al. Recombinant human angiostatin by twicedaily subcutaneous injection in advanced cancer: a pharmacokinetic and long-term safety study. Clin Cancer Res 2003;9:4025-4033.
    • (2003) Clin Cancer Res , vol.9 , pp. 4025-4033
    • Beerepoot, L.V.1    Witteveen, E.O.2    Groenewegen, G.3
  • 7
    • 29844452745 scopus 로고    scopus 로고
    • Recombinant human angiostatin (rhAngiostatin) in combination with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer: A phase II study from Indiana University
    • Kurup A, Lin C, Murry DJ, et al. Recombinant human angiostatin (rhAngiostatin) in combination with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer: a phase II study from Indiana University. Ann Oncol 2006;17: 97-103.
    • (2006) Ann Oncol , vol.17 , pp. 97-103
    • Kurup, A.1    Lin, C.2    Murry, D.J.3
  • 8
    • 70449556825 scopus 로고    scopus 로고
    • The antitumorigenic trifecta
    • Mowery YM, Pizzo SV. The antitumorigenic trifecta. Blood 2009;114:1727-1728.
    • (2009) Blood , vol.114 , pp. 1727-1728
    • Mowery, Y.M.1    Pizzo, S.V.2
  • 9
    • 40949129489 scopus 로고    scopus 로고
    • Linking antibody Fc domain to endostatin significantly improves endostatin half-life and efficacy
    • Lee TY, Tjin Tham Sjin RM, Movahedi S, et al. Linking antibody Fc domain to endostatin significantly improves endostatin half-life and efficacy. Clin Cancer Res 2008;14:1487-1493.
    • (2008) Clin Cancer Res , vol.14 , pp. 1487-1493
    • Lee, T.Y.1    Tjin Tham Sjin, R.M.2    Movahedi, S.3
  • 10
    • 0032031748 scopus 로고    scopus 로고
    • Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases
    • Cao Y, O'Reilly MS, Marshall B, et al. Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases. J Clin Invest 1998;101:1055-1063.
    • (1998) J Clin Invest , vol.101 , pp. 1055-1063
    • Cao, Y.1    O'Reilly, M.S.2    Marshall, B.3
  • 11
    • 43749084192 scopus 로고    scopus 로고
    • Mutation of human plasminogen kringle 1-5 enhances antiangiogenic action via increased interaction with integrin avb3
    • Chang PC, Chang YJ, Wu HL, et al. Mutation of human plasminogen kringle 1-5 enhances antiangiogenic action via increased interaction with integrin avb3. Thromb Haemost 2008;99:729-738.
    • (2008) Thromb Haemost , vol.99 , pp. 729-738
    • Chang, P.C.1    Chang, Y.J.2    Wu, H.L.3
  • 12
    • 73849115332 scopus 로고    scopus 로고
    • Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid
    • Jullienne B, Vigant F, Muth E, et al. Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid. Gene Ther 2009;16:1405-1415.
    • (2009) Gene Ther , vol.16 , pp. 1405-1415
    • Jullienne, B.1    Vigant, F.2    Muth, E.3
  • 13
    • 70349248380 scopus 로고    scopus 로고
    • Angiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteins
    • Lee TY, Muschal S, Pravda EA, et al. Angiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteins. Blood 2009;114:1987-1998.
    • (2009) Blood , vol.114 , pp. 1987-1998
    • Lee, T.Y.1    Muschal, S.2    Pravda, E.A.3
  • 14
    • 84864871735 scopus 로고    scopus 로고
    • Development of the hybrid Sleeping Beauty: Baculovirus vector for sustained gene expression and cancer therapy
    • Luo WY, Shih YS, Hung CL, et al. Development of the hybrid Sleeping Beauty: baculovirus vector for sustained gene expression and cancer therapy. Gene Ther 2012;19:844-851.
    • (2012) Gene Ther , vol.19 , pp. 844-851
    • Luo, W.Y.1    Shih, Y.S.2    Hung, C.L.3
  • 15
    • 1642342770 scopus 로고    scopus 로고
    • Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: Long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor
    • Ponnazhagan S, Mahendra G, Kumar S, et al. Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor. Cancer Res 2004; 64:1781-1787.
    • (2004) Cancer Res , vol.64 , pp. 1781-1787
    • Ponnazhagan, S.1    Mahendra, G.2    Kumar, S.3
  • 16
    • 33750046350 scopus 로고    scopus 로고
    • Liposome-mediated gene transfer of K1-5 suppresses tumor development and improves the prognosis of hepatocellular carcinoma in mice
    • Torimura T, Ueno T, Sata M. Liposome-mediated gene transfer of K1-5 suppresses tumor development and improves the prognosis of hepatocellular carcinoma in mice. Med Mol Morphol 2006;39:72-78.
    • (2006) Med Mol Morphol , vol.39 , pp. 72-78
    • Torimura, T.1    Ueno, T.2    Sata, M.3
  • 17
    • 0033545930 scopus 로고    scopus 로고
    • Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis
    • Cao R, Wu HL, Veitonmaki N, et al. Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis. Proc Natl Acad Sci USA 1999;96: 5728-5733.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5728-5733
    • Cao, R.1    Wu, H.L.2    Veitonmaki, N.3
  • 18
    • 79954650563 scopus 로고    scopus 로고
    • State-of-the-art gene-based therapies: The road ahead
    • Kay MA. State-of-the-art gene-based therapies: the road ahead. Nat Rev Genet 2011;12:316-328.
    • (2011) Nat Rev Genet , vol.12 , pp. 316-328
    • Kay, M.A.1
  • 19
    • 77950961700 scopus 로고    scopus 로고
    • Future prospects and challenges of antiangiogenic cancer gene therapy
    • Samaranayake H, Maatta AM, Pikkarainen J, et al. Future prospects and challenges of antiangiogenic cancer gene therapy. Hum Gene Ther 2010;21:381-396.
    • (2010) Hum Gene Ther , vol.21 , pp. 381-396
    • Samaranayake, H.1    Maatta, A.M.2    Pikkarainen, J.3
  • 20
    • 77953251302 scopus 로고    scopus 로고
    • Viral vectors for gene transfer: Current status of gene therapeutics
    • Heilbronn R, Weger S. Viral vectors for gene transfer: current status of gene therapeutics. Handb Exp Pharmacol 2010;197:143-170.
    • (2010) Handb Exp Pharmacol , vol.197 , pp. 143-170
    • Heilbronn, R.1    Weger, S.2
  • 21
    • 84863011918 scopus 로고    scopus 로고
    • The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis y antigen
    • Kuo CH, Chen PK, Chang BI, et al. The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis Y antigen. Blood 2012;119:1302-1313.
    • (2012) Blood , vol.119 , pp. 1302-1313
    • Kuo, C.H.1    Chen, P.K.2    Chang, B.I.3
  • 22
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • Xiao X, Li J, Samulski RJ. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J Virol 1998;72: 2224-2232.
    • (1998) J Virol , vol.72 , pp. 2224-2232
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 23
    • 79953244361 scopus 로고    scopus 로고
    • Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis
    • Ebos JM, Kerbel RS. Antiangiogenic therapy: impact on invasion, disease progression, and metastasis. Nat Rev Clin Oncol 2011;8:210-221.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 210-221
    • Ebos, J.M.1    Kerbel, R.S.2
  • 24
    • 84880289352 scopus 로고    scopus 로고
    • A largely random AAV integration profile after LPLD gene therapy
    • Kaeppel C, Beattie SG, Fronza R, et al. A largely random AAV integration profile after LPLD gene therapy. Nat Med 2013;19:889-891.
    • (2013) Nat Med , vol.19 , pp. 889-891
    • Kaeppel, C.1    Beattie, S.G.2    Fronza, R.3
  • 25
    • 38449089618 scopus 로고    scopus 로고
    • Cancer gene therapy using adeno-associated virus vectors
    • Park K, Kim WJ, Cho YH, et al. Cancer gene therapy using adeno-associated virus vectors. Front Biosci 2008;13:2653-2659.
    • (2008) Front Biosci , vol.13 , pp. 2653-2659
    • Park, K.1    Kim, W.J.2    Cho, Y.H.3
  • 26
    • 79955597265 scopus 로고    scopus 로고
    • Longterm safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins
    • Nathwani AC, Rosales C, Mcintosh J, et al. Longterm safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins. Mol Ther 2011;19:876-885.
    • (2011) Mol Ther , vol.19 , pp. 876-885
    • Nathwani, A.C.1    Rosales, C.2    Mcintosh, J.3
  • 27
    • 84855161388 scopus 로고    scopus 로고
    • Adenovirus-associated virus vector-mediated gene transfer in hemophilia B
    • Nathwani AC, Tuddenham EG, Rangarajan S, et al. Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med 2011;365: 2357-2365.
    • (2011) N Engl J Med , vol.365 , pp. 2357-2365
    • Nathwani, A.C.1    Tuddenham, E.G.2    Rangarajan, S.3
  • 28
    • 79952258871 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus type 2 pseudotypes: Comparing safety, specificity, and transduction efficiency in the primate striatum: Laboratory investigation
    • Sanchez CE, Tierney TS, Gale JT, et al. Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum: laboratory investigation. J Neurosurg 2011;114: 672-680.
    • (2011) J Neurosurg , vol.114 , pp. 672-680
    • Sanchez, C.E.1    Tierney, T.S.2    Gale, J.T.3
  • 29
    • 44049094771 scopus 로고    scopus 로고
    • Clinical gene therapy using recombinant adeno-associated virus vectors
    • Mueller C, Flotte TR. Clinical gene therapy using recombinant adeno-associated virus vectors. Gene Ther 2008;15:858-863.
    • (2008) Gene Ther , vol.15 , pp. 858-863
    • Mueller, C.1    Flotte, T.R.2
  • 30
    • 33644820684 scopus 로고    scopus 로고
    • Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
    • Manno CS, Pierce GF, Arruda VR, et al. Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat Med 2006;12:342-347.
    • (2006) Nat Med , vol.12 , pp. 342-347
    • Manno, C.S.1    Pierce, G.F.2    Arruda, V.R.3
  • 31
    • 0037015049 scopus 로고    scopus 로고
    • Novel adenoassociated viruses from rhesus monkeys as vectors for human gene therapy
    • Gao GP, Alvira MR, Wang L, et al. Novel adenoassociated viruses from rhesus monkeys as vectors for human gene therapy. Proc Natl Acad Sci USA 2002;99:11854-11859.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11854-11859
    • Gao, G.P.1    Alvira, M.R.2    Wang, L.3
  • 32
    • 10644289281 scopus 로고    scopus 로고
    • Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice
    • Nakai H, Fuess S, Storm TA, et al. Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice. J Virol 2005;79: 214-224.
    • (2005) J Virol , vol.79 , pp. 214-224
    • Nakai, H.1    Fuess, S.2    Storm, T.A.3
  • 33
    • 79959972143 scopus 로고    scopus 로고
    • Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer
    • Vanrell L, Di Scala M, Blanco L, et al. Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer. Mol Ther 2011;19:1245-1253.
    • (2011) Mol Ther , vol.19 , pp. 1245-1253
    • Vanrell, L.1    Di Scala, M.2    Blanco, L.3
  • 34
    • 80053492356 scopus 로고    scopus 로고
    • Advancements in adeno-associated viral gene therapy approaches: Exploring a new horizon
    • Aalbers CJ, Tak PP, Vervoordeldonk MJ. Advancements in adeno-associated viral gene therapy approaches: exploring a new horizon. F1000 Med Rep 2011;3:17.
    • (2011) F1000 Med Rep , vol.3 , pp. 17
    • Aalbers, C.J.1    Tak, P.P.2    Vervoordeldonk, M.J.3
  • 35
    • 84871945466 scopus 로고    scopus 로고
    • Adeno-associated viral vectors for gene therapy of inherited retinal degenerations
    • Flannery JG, Visel M. Adeno-associated viral vectors for gene therapy of inherited retinal degenerations. Methods Mol Biol 2013;935:351-369.
    • (2013) Methods Mol Biol , vol.935 , pp. 351-369
    • Flannery, J.G.1    Visel, M.2
  • 36
    • 1142299564 scopus 로고    scopus 로고
    • Anti-tumor efficacy of human angiostatin using liver-mediated adeno-associated virus gene therapy
    • Lalani AS, Chang B, Lin J, et al. Anti-tumor efficacy of human angiostatin using liver-mediated adeno-associated virus gene therapy. Mol Ther 2004;9:56-66.
    • (2004) Mol Ther , vol.9 , pp. 56-66
    • Lalani, A.S.1    Chang, B.2    Lin, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.