Mutation of human plasminogen kringle 1-5 enhances anti-angiogenic action via increased interaction with integrin αvβ3

Thrombosis and Haemostasis

Volumn 99, Issue 4, 2008, Pages 729-738

  Chang, Po Chiao ^a   Chang, Yu Jia ^a   Wu, Hua Lin ^a,b   Chang, Chin Wei ^a   Lin, Chung I ^a   Wang, Wei Chih ^a   Shi, Guey Yueh ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Angiogenesis and inhibitors; Endothelial cells; Integrins; Plasminogen ( fragments)

Indexed keywords

AMINO ACID; ANGIOSTATIN; FIBROBLAST GROWTH FACTOR; MATRIGEL; MUTANT PROTEIN; PLASMINOGEN; VITRONECTIN RECEPTOR;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE MUTATION; GLYCOSYLATION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PURIFICATION; TUMOR GROWTH; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; APOPTOSIS; BASE SEQUENCE; CARCINOMA, LEWIS LUNG; CATTLE; CELL PROLIFERATION; CELLS, CULTURED; DNA PRIMERS; ENDOTHELIAL CELLS; GLYCOSYLATION; HUMANS; INTEGRIN ALPHAVBETA3; KRINGLES; MALE; MICE; MICE, INBRED C57BL; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; PEPTIDE FRAGMENTS; PLASMINOGEN; RECOMBINANT PROTEINS;

EID: 43749084192     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH07-06-0403     Document Type: Article

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