Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 10, 1999, Pages 5728-5733

  Cao, Renhai ^a   Wu, Hua Lin ^b   Veitonmäki, Niina ^a   Linden, Philip ^c   Farnebo, Jacob ^a   Shi, Guey Yueh ^b   Cao, Yihai ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Angiostatin; Antitumor; Plasminogen

Indexed keywords

ANGIOGENESIS INHIBITOR; FIBROBLAST GROWTH FACTOR; PLASMIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; KRINGLE DOMAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; TUMOR VASCULARIZATION;

ANGIOSTATINS; ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; CELL DIVISION; CHICK EMBRYO; CHOROIDAL NEOVASCULARIZATION; CORNEAL NEOVASCULARIZATION; ENDOTHELIUM, VASCULAR; FIBROSARCOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDE FRAGMENTS; PLASMIN; PLASMINOGEN; TUMOR CELLS, CULTURED;

ANIMALIA; GALLUS GALLUS; MURINAE;

EID: 0033545930     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.10.5728     Document Type: Article

References (43)

1. Folkman, J. & Shing, Y. (1992) J. Biol. Chem. 267, 10931-10934.
2. Folkman, J. & D'Amore, P. (1996) Cell 87, 1153-1155.
3. Risau, W. (1997) Nature (London) 386, 671-674.
4. Hanahan, D. & Folkman, J. (1996) Cell 86, 353-364.
5. O'Reilly, M. S., Holmgren, L., Shing, Y., Chen, C., Rosenthal, R. A., Moses, M., Lane, W. S., Cao, Y., Sage, E. H. & Folkman, J. (1994) Cell 79, 315-328.
6. Brooks, P. C., Montgomery, A. M., Rosenfeld, M., R. A., R., Hu, T., Klier, G. & Cheresh, D. A. (1994) Cell 79, 1157-1164.
7. O'Reilly, M. S., Holmgren, L., Chen, C. & Folkman, J. (1996) Nat. Med. 2, 689-692.
8. Folkman, J. (1995a) Nat. Med. 1, 27-31.
9. Good, D. J., Polverini, P. J., Rastinejad, F., LeBeau, M. M., Lemons, R. S., Frazier, W. A. & Bouck, N. P. (1990) Proc. Natl. Acad. Sci. USA 87, 6624-6628.
10. Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Phillips, H. S. & Ferrara, N. (1993) Nature (London) 362, 841-844.
11. Kandel, J., Bossy-Wetzel, E., Radvanyi, F., Klagsbrun, M., Folkman, J. & Hanahan, D. (1991) Cell 66, 1095-1104.
12. Senger, D. R., Galli, S. J., Dvorak, A. M., Perruzzi, C. A., Harvey, V. S. & Dvorak, H. F. (1983) Science 219, 983-985.
13. Ferrara, N. & Davis-Smyth, T. (1997) Endocr. Rev. 18, 4-25.
14. Nguyen, M., Watanabe, H., Budson, A. E., Richie, J. P., Hayes, D. F. & Folkman, J. (1994) J. Natl. Cancer Inst. 86, 356-361.
15. Mustonen, T. & Alitalo, K. (1995) J. Cell Biol. 129, 895-898.
16. Pepper, M. S., Ferrara, N., Orci, L. & Montesano, R. (1992) Biochem. Biophys. Res. Commun. 189, 824-831.
17. Cao, Y., Ji, R.-W., Davidson, D., Schaller, J., Marti, D., Sohndel, S.. McCance, S. G., O'Reilly, M. S., Llinas, M. & Folkman, J. (1996) J. Biol. Chem. 271, 29461-29467.
18. Holmgren, L., O'Reilly, M. S. & Folkman, J. (1995) Nat. Med. 1, 149-153.
19. O'Reilly, M. S., Boehm, T., Shing, Y., Fuhai, N., Vasios, G., Lane, W. S., Flynn, E., Birkhead, J. R., Olsen, B. & Folkman, J. (1997) Cell 88, 1-20.
20. Boehm, T., Folkman, J., T., B. & O'Reilly, M. S. (1997) Nature (London) 390, 335-336.
21. Volpert, O. V., Lawler, J. & Bouck, N. P. (1998) Proc. Natl. Acad. Sci. USA 95, 6343-6348.
22. Cao, Y. (1998) Progress in Molecular and Subcellular Biology- Inhibitors of Cell Growth (Springer, Berlin; Heidelberg; London; New York), Vol. 20, pp. 161-176.
23. Cao, Y., Chen, A., An, S. S. A., Ji, R. W. D., Davidson, D., Cao, Y. M. & Llinas, M. (1997) J. Biol. Chem. 272, 22924-22928.
24. Clapp, C., Martial, J. A., Guzman, R. C., Rentierdelrue, F. & Weiner, R. I. (1993) Endorinology 133, 1292-1299.
25. Gupta, S. K., Hassel, T. & Singh, J. P. (1995) Proc. Natl. Acad. Sci. USA 92, 7799-7803.
26. Brooks, P. C., Silletti, S., Schalscha, T. L., Friedlander, M. & Cheresh, D. (1998) Cell 92, 391-400.
27. Cao, Y., O'Reilly, M. S., Marshall, B., Flynn, E., Ji, W. R. & Folkman, J. (1998) J. Clin. Invest. 101, 1055-1063.
28. Cao, Y. & Pettersson, R. F. (1990) Growth Factors 3, 1-13.
29. Wu, H. L., Chang, B. I., Wu, D. H., Chang, L. C., Gong, C. C., Lou, K. L. & Shi, G. Y. (1990) J. Biol. Chem. 265, 19658-19664.
30. Folkman, J., Haudenschild, C. C. & Zetter, B. R. (1979) Proc. Natl. Acad. Sci. USA 76, 5217-5121.
31. Cao, Y., Chen, C., Weatherbee, J. A., Tsang, M. & Folkman, J. (1995) J. Exp. Med. 182, 2069-2077.
32. Nguyen, M., Shing, Y. & Filkman, J. (1994) Microvascular Res. 47, 31-40.
33. Kenyon, B. M., Voest, E. E., Chen, C., Flynn, E., Folkman, J. & D'Amato, R. J. (1996) Invest. Ophthal. Visual Sci. 37, 1625-1632.
34. Jain, R. K., Schlenger, K., Hockel, M. & F., Yuan. (1997) Nat. Med. 3, 1203-1208.
35. Gately, S., Twardowski, P., Stack, M. S., Patrick, M., Boggio, L., Cundiff, D. L., Schnaper, H. W., Madison, L., Volpert, O., Bouck, N., et al. (1997) Cancer Res. 56, 4887-4890.
36. Stathakis, P., Fitzgerald, M., Matthias, L. J., Chesterman, C. N. & Hogg, P. J. (1997) J. Biol. Chem. 272, 20641-20645.
37. Dong, Z., Kumar, R., Yang, X. & Fidler, I. J. (1997) Cell 88, 801-810.
38. Lijnen, H. R., Ugwu, F., Bini, A. & Collen, D. (1998) Biochemistry 37, 4699-4702.
39. Patterson, B. C. & Sang, Q. X. A. (1997) J. Biol. Chem. 272.
40. Claesson-Welsh, L., Welsh, M., Ito, N., Anandapte, B., Soker, S., Zetter, B., O'Reilly, M. & Folkman, J. (1998) Proc. Natl. Acad. Sci. USA 95, 5579-5583.
41. Evans, C. P., Elfman, F., Parangi, S., Conn, M., Cunha, M. & Shuman, M. A. (1997) Cancer Res. 57, 3594-3599.
42. Plouet, J., Moro, F., Bertagnolli, S., Coldeboeuf, N., Mazarguil, H., Clamens, S. & F., B. (1997) J. Biol. Chem. 272, 13390-13396.
43. Nakanishi, Y., Kodama, J., Yoshinouchi, M., Tokumo, K., Kamimura, S., Okuda, H. & Kudo, T. (1997) Int. J. Gynecol. Pathol. 16, 256-262.