Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations

Journal of Molecular and Cellular Cardiology

Volumn 87, Issue , 2015, Pages 204-213

  Liu, Ruijie ^a   Correll, Robert N ^a   Davis, Jennifer ^a   Vagnozzi, Ronald J ^a   York, Allen J ^a   Sargent, Michelle A ^a   Nairn, Angus C ^b   Molkentin, Jeffery D ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Contractility; Heart failure; Myofilament protein; Protein phosphatase 1

Indexed keywords

MYOSIN BINDING PROTEIN C; MYOSIN HEAVY CHAIN ALPHA; MYOSIN LIGHT CHAIN 2; PHOSPHOLAMBAN; TAMOXIFEN; ACTIN BINDING PROTEIN; ISOPROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PPM1B PROTEIN, MOUSE; PROTEIN PHOSPHATASE 2C; VENTRICULAR MYOSIN;

ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE; GENE DELETION; GENE FUNCTION; GENE TARGETING; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; MERCREMER TRANSGENE; MOUSE; MYOFILAMENT; NONHUMAN; PPP1CA GENE; PPP1CB GENE; PPP1CC GENE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOMERE; TRANSGENE; ACTIN FILAMENT; ANIMAL; GENETICS; HEART; HEART CONTRACTION; HUMAN; METABOLISM; MUSCLE FIBRIL; PHOSPHORYLATION; PHYSIOLOGY;

ACTIN CYTOSKELETON; ANIMALS; GENE KNOCK-IN TECHNIQUES; HEART; HUMANS; MICE; MICROFILAMENT PROTEINS; MYOCARDIAL CONTRACTION; MYOFIBRILS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN PHOSPHATASE 2C; SARCOMERES; VENTRICULAR MYOSINS;

EID: 84941265160     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.08.018     Document Type: Article

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