-
1
-
-
0000187410
-
Conversion of phosphorylase b to phosphorylase a in muscle extracts
-
Fischer E.H., Krebs E.G. Conversion of phosphorylase b to phosphorylase a in muscle extracts. J Biol Chem 1955, 216:121-132.
-
(1955)
J Biol Chem
, vol.216
, pp. 121-132
-
-
Fischer, E.H.1
Krebs, E.G.2
-
2
-
-
0036097364
-
The origins of protein phosphorylation
-
Cohen P. The origins of protein phosphorylation. Nat Cell Biol 2002, 4:E127-E130.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Cohen, P.1
-
3
-
-
0016411763
-
Control of calcium transport in the myocardium by the cyclic AMP-protein kinase system
-
Katz A.M., Tada M., Kirchberger M.A. Control of calcium transport in the myocardium by the cyclic AMP-protein kinase system. Adv Cyclic Nucleotide Res 1975, 5:453-472.
-
(1975)
Adv Cyclic Nucleotide Res
, vol.5
, pp. 453-472
-
-
Katz, A.M.1
Tada, M.2
Kirchberger, M.A.3
-
4
-
-
84857047339
-
PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
-
Hornbeck P.V., Kornhauser J.M., Tkachev S., Zhang B., Skrzypek E., Murray B., et al. PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse. Nucleic Acids Res 2012, 40:D261-D270.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Hornbeck, P.V.1
Kornhauser, J.M.2
Tkachev, S.3
Zhang, B.4
Skrzypek, E.5
Murray, B.6
-
5
-
-
70350340056
-
Serine/threonine phosphatases: mechanism through structure
-
Shi Y. Serine/threonine phosphatases: mechanism through structure. Cell 2009, 139:468-484.
-
(2009)
Cell
, vol.139
, pp. 468-484
-
-
Shi, Y.1
-
6
-
-
61649127812
-
From promiscuity to precision: protein phosphatases get a makeover
-
Virshup D.M., Shenolikar S. From promiscuity to precision: protein phosphatases get a makeover. Mol Cell 2009, 33:537-545.
-
(2009)
Mol Cell
, vol.33
, pp. 537-545
-
-
Virshup, D.M.1
Shenolikar, S.2
-
7
-
-
0020565637
-
Protein phosphatases: properties and role in cellular-regulation
-
Ingebritsen T.S., Cohen P. Protein phosphatases: properties and role in cellular-regulation. Science 1983, 221:331-338.
-
(1983)
Science
, vol.221
, pp. 331-338
-
-
Ingebritsen, T.S.1
Cohen, P.2
-
8
-
-
0033954554
-
Effects of serine/threonine protein phosphatases on ion channels in excitable membranes
-
Herzig S., Neumann J. Effects of serine/threonine protein phosphatases on ion channels in excitable membranes. Physiol Rev 2000, 80:173-210.
-
(2000)
Physiol Rev
, vol.80
, pp. 173-210
-
-
Herzig, S.1
Neumann, J.2
-
9
-
-
70449116100
-
Beta-adrenergic stimulation and myocardial function in the failing heart
-
El-Armouche A., Eschenhagen T. Beta-adrenergic stimulation and myocardial function in the failing heart. Heart Fail Rev 2009, 14:225-241.
-
(2009)
Heart Fail Rev
, vol.14
, pp. 225-241
-
-
El-Armouche, A.1
Eschenhagen, T.2
-
10
-
-
0024397415
-
The structure and regulation of protein phosphatases
-
Cohen P. The structure and regulation of protein phosphatases. Annu Rev Biochem 1989, 58:453-508.
-
(1989)
Annu Rev Biochem
, vol.58
, pp. 453-508
-
-
Cohen, P.1
-
12
-
-
84872769362
-
The PP1 binding code: a molecular-lego strategy that governs specificity
-
Heroes E., Lesage B., Gornemann J., Beullens M., Van Meervelt L., Bollen M. The PP1 binding code: a molecular-lego strategy that governs specificity. FEBS J 2013, 280:584-595.
-
(2013)
FEBS J
, vol.280
, pp. 584-595
-
-
Heroes, E.1
Lesage, B.2
Gornemann, J.3
Beullens, M.4
Van Meervelt, L.5
Bollen, M.6
-
13
-
-
0037081563
-
Protein phosphatase 1-targeted in many directions
-
Cohen P.T. Protein phosphatase 1-targeted in many directions. J Cell Sci 2002, 115:241-256.
-
(2002)
J Cell Sci
, vol.115
, pp. 241-256
-
-
Cohen, P.T.1
-
14
-
-
84872287681
-
Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart
-
DeGrande S.T., Little S.C., Nixon D.J., Wright P., Snyder J., Dun W., et al. Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart. J Biol Chem 2013, 288:1032-1046.
-
(2013)
J Biol Chem
, vol.288
, pp. 1032-1046
-
-
DeGrande, S.T.1
Little, S.C.2
Nixon, D.J.3
Wright, P.4
Snyder, J.5
Dun, W.6
-
15
-
-
20444376531
-
Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays
-
Ellinghaus P., Scheubel R.J., Dobrev D., Ravens U., Holtz J., Huetter J., et al. Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays. J Thorac Cardiovasc Surg 2005, 129:1383-1390.
-
(2005)
J Thorac Cardiovasc Surg
, vol.129
, pp. 1383-1390
-
-
Ellinghaus, P.1
Scheubel, R.J.2
Dobrev, D.3
Ravens, U.4
Holtz, J.5
Huetter, J.6
-
16
-
-
0034525784
-
Regional expression of protein phosphatase type 1 and 2A catalytic subunit isoforms in the human heart
-
Lüss H., Klein-Wiele O., Boknik P., Herzig S., Knapp J., Linck B., et al. Regional expression of protein phosphatase type 1 and 2A catalytic subunit isoforms in the human heart. J Mol Cell Cardiol 2000, 32:2349-2359.
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 2349-2359
-
-
Lüss, H.1
Klein-Wiele, O.2
Boknik, P.3
Herzig, S.4
Knapp, J.5
Linck, B.6
-
17
-
-
84890803550
-
Calcineurin-dependent ion channel regulation in heart
-
[in press]
-
Wang Y., Tandan S., Hill J.A. Calcineurin-dependent ion channel regulation in heart. Trends Cardiovasc Med 2013, [in press]. 10.1016/j.tcm.2013.05.004.
-
(2013)
Trends Cardiovasc Med
-
-
Wang, Y.1
Tandan, S.2
Hill, J.A.3
-
18
-
-
84870954315
-
Mass spectrometry-based identification of native cardiac Nav1.5 channel alpha subunit phosphorylation sites
-
Marionneau C., Lichti C.F., Lindenbaum P., Charpentier F., Nerbonne J.M., Townsend R.R., et al. Mass spectrometry-based identification of native cardiac Nav1.5 channel alpha subunit phosphorylation sites. J Proteome Res 2012, 11:5994-6007.
-
(2012)
J Proteome Res
, vol.11
, pp. 5994-6007
-
-
Marionneau, C.1
Lichti, C.F.2
Lindenbaum, P.3
Charpentier, F.4
Nerbonne, J.M.5
Townsend, R.R.6
-
19
-
-
5444225595
-
+ channel function in epicardial border zone cells that survive in the infarcted canine heart?
-
+ channel function in epicardial border zone cells that survive in the infarcted canine heart?. Cardiovasc Res 2004, 64.
-
(2004)
Cardiovasc Res
, vol.64
-
-
Baba, S.1
Dun, W.2
Boyden, P.A.3
-
20
-
-
84867795118
-
+ channel I-II loop mediates parallel genetic and phosphorylation-dependent gating changes
-
+ channel I-II loop mediates parallel genetic and phosphorylation-dependent gating changes. Circulation 2012, 126:2042-2046.
-
(2012)
Circulation
, vol.126
, pp. 2042-2046
-
-
Bers, D.M.1
Herren, A.W.2
-
21
-
-
0028940325
-
Identification of soluble protein phosphatases that dephosphorylate voltage-sensitive sodium channels in rat brain
-
Chen T.C., Law B., Kondratyuk T., Rossie S. Identification of soluble protein phosphatases that dephosphorylate voltage-sensitive sodium channels in rat brain. J Biol Chem 1995, 270:7750-7756.
-
(1995)
J Biol Chem
, vol.270
, pp. 7750-7756
-
-
Chen, T.C.1
Law, B.2
Kondratyuk, T.3
Rossie, S.4
-
23
-
-
0037127028
-
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel
-
Marx S.O., Kurokawa J., Reiken S., Motoike H., D'Armiento J., Marks A.R., et al. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science 2002, 295:496-499.
-
(2002)
Science
, vol.295
, pp. 496-499
-
-
Marx, S.O.1
Kurokawa, J.2
Reiken, S.3
Motoike, H.4
D'Armiento, J.5
Marks, A.R.6
-
24
-
-
82655181353
-
Phospholemman-dependent regulation of the cardiac Na/K-ATPase activity is modulated by inhibitor-1 sensitive type-1 phosphatase
-
El-Armouche A., Wittkopper K., Fuller W., Howie J., Shattock M.J., Pavlovic D. Phospholemman-dependent regulation of the cardiac Na/K-ATPase activity is modulated by inhibitor-1 sensitive type-1 phosphatase. FASEB J 2011, 25:4467-4475.
-
(2011)
FASEB J
, vol.25
, pp. 4467-4475
-
-
El-Armouche, A.1
Wittkopper, K.2
Fuller, W.3
Howie, J.4
Shattock, M.J.5
Pavlovic, D.6
-
25
-
-
34547131050
-
Molecular basis for PP2A regulatory subunit B56α targeting in cardiomyocytes
-
Bhasin N., Cunha S.R., Mudannayake M., Gigena M.S., Rogers T.B., Mohler P.J. Molecular basis for PP2A regulatory subunit B56α targeting in cardiomyocytes. Am J Physiol Heart Circ Physiol 2007, 293:H109-H119.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Bhasin, N.1
Cunha, S.R.2
Mudannayake, M.3
Gigena, M.S.4
Rogers, T.B.5
Mohler, P.J.6
-
28
-
-
34247894032
-
Differential phosphorylation-dependent regulation of constitutively active and muscarinic receptor-activated IK, ACh channels in patients with chronic atrial fibrillation
-
Voigt N., Friedrich A., Bock M., Wettwer E., Christ T., Knaut M., et al. Differential phosphorylation-dependent regulation of constitutively active and muscarinic receptor-activated IK, ACh channels in patients with chronic atrial fibrillation. Cardiovasc Res 2007, 74:426-437.
-
(2007)
Cardiovasc Res
, vol.74
, pp. 426-437
-
-
Voigt, N.1
Friedrich, A.2
Bock, M.3
Wettwer, E.4
Christ, T.5
Knaut, M.6
-
30
-
-
33644849005
-
Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser 1928, its main PKA site, is critical for Ser1928 dephosphorylation
-
Hall D.D., Feekes J.A., Arachchige Don A.S., Shi M., Hamid J., Chen L., et al. Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser 1928, its main PKA site, is critical for Ser1928 dephosphorylation. Biochemistry 2006, 45:3448-3459.
-
(2006)
Biochemistry
, vol.45
, pp. 3448-3459
-
-
Hall, D.D.1
Feekes, J.A.2
Arachchige Don, A.S.3
Shi, M.4
Hamid, J.5
Chen, L.6
-
31
-
-
0036274039
-
Regulation of ryanodine receptors via macromolecular complexes: a novel role for leucine/isoleucine zippers
-
Marks A.R., Marx S.O., Reiken S. Regulation of ryanodine receptors via macromolecular complexes: a novel role for leucine/isoleucine zippers. Trends Cardiovasc Med 2002, 12:166-170.
-
(2002)
Trends Cardiovasc Med
, vol.12
, pp. 166-170
-
-
Marks, A.R.1
Marx, S.O.2
Reiken, S.3
-
32
-
-
82755165053
-
MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex
-
Belevych A.E., Sansom S.E., Terentyeva R., Ho H.T., Nishijima Y., Martin M.M., et al. MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex. PLoS One 2011, 6:e28324.
-
(2011)
PLoS One
, vol.6
-
-
Belevych, A.E.1
Sansom, S.E.2
Terentyeva, R.3
Ho, H.T.4
Nishijima, Y.5
Martin, M.M.6
-
33
-
-
61949226650
-
2+ release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56α and causing CaMKII-dependent hyperphosphorylation of RyR2
-
2+ release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56α and causing CaMKII-dependent hyperphosphorylation of RyR2. Circ Res 2009, 104:514-521.
-
(2009)
Circ Res
, vol.104
, pp. 514-521
-
-
Terentyev, D.1
Belevych, A.E.2
Terentyeva, R.3
Martin, M.M.4
Malana, G.E.5
Kuhn, D.E.6
-
34
-
-
77951245640
-
CAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3
-
Dodge-Kafka K.L., Bauman A., Mayer N., Henson E., Heredia L., Ahn J., et al. cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3. J Biol Chem 2010, 285:11078-11086.
-
(2010)
J Biol Chem
, vol.285
, pp. 11078-11086
-
-
Dodge-Kafka, K.L.1
Bauman, A.2
Mayer, N.3
Henson, E.4
Heredia, L.5
Ahn, J.6
-
35
-
-
82255177626
-
Reorganized PKA-AKAP associations in the failing human heart
-
Aye T.T., Soni S., van Veen T.A., van der Heyden M.A., Cappadona S., Varro A., et al. Reorganized PKA-AKAP associations in the failing human heart. J Mol Cell Cardiol 2012, 52:511-518.
-
(2012)
J Mol Cell Cardiol
, vol.52
, pp. 511-518
-
-
Aye, T.T.1
Soni, S.2
van Veen, T.A.3
van der Heyden, M.A.4
Cappadona, S.5
Varro, A.6
-
36
-
-
0042206722
-
Sodium/calcium exchanger (NCX1) macromolecular complex
-
Schulze D.H., Muqhal M., Lederer W.J., Ruknudin A.M. Sodium/calcium exchanger (NCX1) macromolecular complex. J Biol Chem 2003, 278:28849-28855.
-
(2003)
J Biol Chem
, vol.278
, pp. 28849-28855
-
-
Schulze, D.H.1
Muqhal, M.2
Lederer, W.J.3
Ruknudin, A.M.4
-
38
-
-
79953179309
-
Protein phosphorylation and signal transduction in cardiac thin filaments
-
Solaro R.J., Kobayashi T. Protein phosphorylation and signal transduction in cardiac thin filaments. J Biol Chem 2011, 286:9935-9940.
-
(2011)
J Biol Chem
, vol.286
, pp. 9935-9940
-
-
Solaro, R.J.1
Kobayashi, T.2
-
39
-
-
84861884235
-
Cardiac myosin binding protein C phosphorylation in cardiac disease
-
Kuster D.W., Bawazeer A.C., Zaremba R., Goebel M., Boontje N.M., van der Velden J. Cardiac myosin binding protein C phosphorylation in cardiac disease. J Muscle Res Cell Motil 2012, 33:43-52.
-
(2012)
J Muscle Res Cell Motil
, vol.33
, pp. 43-52
-
-
Kuster, D.W.1
Bawazeer, A.C.2
Zaremba, R.3
Goebel, M.4
Boontje, N.M.5
van der Velden, J.6
-
40
-
-
84878650247
-
Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts
-
Kooij V., Holewinski R.J., Murphy A.M., Van Eyk J.E. Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts. J Mol Cell Cardiol 2013, 60:116-120.
-
(2013)
J Mol Cell Cardiol
, vol.60
, pp. 116-120
-
-
Kooij, V.1
Holewinski, R.J.2
Murphy, A.M.3
Van Eyk, J.E.4
-
41
-
-
77649109602
-
Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution
-
Yin X., Cuello F., Mayr U., Hao Z., Hornshaw M., Ehler E., et al. Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution. Mol Cell Proteomics 2010, 9:497-509.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 497-509
-
-
Yin, X.1
Cuello, F.2
Mayr, U.3
Hao, Z.4
Hornshaw, M.5
Ehler, E.6
-
42
-
-
84861643461
-
Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues
-
Marquez-Rosado L., Solan J.L., Dunn C.A., Norris R.P., Lampe P.D. Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues. Biochim Biophys Acta 1818, 2012:1985-1992.
-
(1818)
Biochim Biophys Acta
, vol.2012
, pp. 1985-1992
-
-
Marquez-Rosado, L.1
Solan, J.L.2
Dunn, C.A.3
Norris, R.P.4
Lampe, P.D.5
-
43
-
-
80052897334
-
Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43
-
Ai X., Jiang A., Ke Y., Solaro R.J., Pogwizd S.M. Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43. Cardiovasc Res 2011, 92:106-114.
-
(2011)
Cardiovasc Res
, vol.92
, pp. 106-114
-
-
Ai, X.1
Jiang, A.2
Ke, Y.3
Solaro, R.J.4
Pogwizd, S.M.5
-
44
-
-
0037365794
-
Evidence for protein phosphatase inhibitor-1 playing an amplifier role in beta-adrenergic signaling in cardiac myocytes
-
El-Armouche A., Rau T., Zolk O., Ditz D., Pamminger T., Zimmermann W.H., et al. Evidence for protein phosphatase inhibitor-1 playing an amplifier role in beta-adrenergic signaling in cardiac myocytes. FASEB J 2003, 17:437-439.
-
(2003)
FASEB J
, vol.17
, pp. 437-439
-
-
El-Armouche, A.1
Rau, T.2
Zolk, O.3
Ditz, D.4
Pamminger, T.5
Zimmermann, W.H.6
-
45
-
-
79952000271
-
The large isoforms of A-kinase anchoring protein 18 mediate the phosphorylation of inhibitor-1 by protein kinase A and the inhibition of protein phosphatase 1 activity
-
Singh A., Redden J.M., Kapiloff M.S., Dodge-Kafka K.L. The large isoforms of A-kinase anchoring protein 18 mediate the phosphorylation of inhibitor-1 by protein kinase A and the inhibition of protein phosphatase 1 activity. Mol Pharmacol 2011, 79:533-540.
-
(2011)
Mol Pharmacol
, vol.79
, pp. 533-540
-
-
Singh, A.1
Redden, J.M.2
Kapiloff, M.S.3
Dodge-Kafka, K.L.4
-
46
-
-
33745205607
-
Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes
-
El-Armouche A., Bednorz A., Pamminger T., Ditz D., Didie M., Dobrev D., et al. Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes. Biochem Biophys Res Commun 2006, 346:700-706.
-
(2006)
Biochem Biophys Res Commun
, vol.346
, pp. 700-706
-
-
El-Armouche, A.1
Bednorz, A.2
Pamminger, T.3
Ditz, D.4
Didie, M.5
Dobrev, D.6
-
47
-
-
76649092318
-
Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging
-
Wittkopper K., Fabritz L., Neef S., Ort K.R., Grefe C., Unsold B., et al. Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging. J Clin Invest 2010, 120:617-626.
-
(2010)
J Clin Invest
, vol.120
, pp. 617-626
-
-
Wittkopper, K.1
Fabritz, L.2
Neef, S.3
Ort, K.R.4
Grefe, C.5
Unsold, B.6
-
48
-
-
33847671760
-
Phosphorylation and functions of inhibitor-2 family of proteins
-
Li M., Satinover D.L., Brautigan D.L. Phosphorylation and functions of inhibitor-2 family of proteins. Biochemistry 2007, 46:2380-2389.
-
(2007)
Biochemistry
, vol.46
, pp. 2380-2389
-
-
Li, M.1
Satinover, D.L.2
Brautigan, D.L.3
-
49
-
-
63849141619
-
Role of PP1 in the regulation of Ca cycling in cardiac physiology and pathophysiology
-
Nicolaou P., Kranias E.G. Role of PP1 in the regulation of Ca cycling in cardiac physiology and pathophysiology. Front Biosci 2009, 14:3571-3585.
-
(2009)
Front Biosci
, vol.14
, pp. 3571-3585
-
-
Nicolaou, P.1
Kranias, E.G.2
-
50
-
-
79958825289
-
Small heat shock protein 20 interacts with protein phosphatase-1 and enhances sarcoplasmic reticulum calcium cycling
-
Qian J., Vafiadaki E., Florea S.M., Singh V.P., Song W., Lam C.K., et al. Small heat shock protein 20 interacts with protein phosphatase-1 and enhances sarcoplasmic reticulum calcium cycling. Circ Res 2011, 108:1429-1438.
-
(2011)
Circ Res
, vol.108
, pp. 1429-1438
-
-
Qian, J.1
Vafiadaki, E.2
Florea, S.M.3
Singh, V.P.4
Song, W.5
Lam, C.K.6
-
51
-
-
0032843737
-
Structure-based functional motif identifies a potential disulfide oxidoreductase active site in the serine/threonine protein phosphatase-1 subfamily
-
Fetrow J.S., Siew N., Skolnick J. Structure-based functional motif identifies a potential disulfide oxidoreductase active site in the serine/threonine protein phosphatase-1 subfamily. FASEB J 1999, 13:1866-1874.
-
(1999)
FASEB J
, vol.13
, pp. 1866-1874
-
-
Fetrow, J.S.1
Siew, N.2
Skolnick, J.3
-
52
-
-
0027217027
-
Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A
-
Honkanen R.E. Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A. FEBS Lett 1993, 330:283-286.
-
(1993)
FEBS Lett
, vol.330
, pp. 283-286
-
-
Honkanen, R.E.1
-
53
-
-
84872091789
-
Heart disease and stroke statistics-2013 update: a report from the American Heart Association
-
Go A.S., Mozaffarian D., Roger V.L., Benjamin E.J., Berry J.D., Borden W.B., et al. Heart disease and stroke statistics-2013 update: a report from the American Heart Association. Circulation 2013, 127:e6-e245.
-
(2013)
Circulation
, vol.127
-
-
Go, A.S.1
Mozaffarian, D.2
Roger, V.L.3
Benjamin, E.J.4
Berry, J.D.5
Borden, W.B.6
-
54
-
-
34248595219
-
Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation
-
Nattel S., Maguy A., Le Bouter S., Yeh Y.H. Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation. Physiol Rev 2007, 87:425-456.
-
(2007)
Physiol Rev
, vol.87
, pp. 425-456
-
-
Nattel, S.1
Maguy, A.2
Le Bouter, S.3
Yeh, Y.H.4
-
55
-
-
82955227502
-
Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium
-
Wijnker P.J., Boknik P., Gergs U., Muller F.U., Neumann J., dos Remedios C., et al. Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium. J Muscle Res Cell Motil 2011, 32:221-233.
-
(2011)
J Muscle Res Cell Motil
, vol.32
, pp. 221-233
-
-
Wijnker, P.J.1
Boknik, P.2
Gergs, U.3
Muller, F.U.4
Neumann, J.5
dos Remedios, C.6
-
56
-
-
0347357650
-
Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts
-
El-Armouche A., Pamminger T., Ditz D., Zolk O., Eschenhagen T. Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts. Cardiovasc Res 2004, 61:87-93.
-
(2004)
Cardiovasc Res
, vol.61
, pp. 87-93
-
-
El-Armouche, A.1
Pamminger, T.2
Ditz, D.3
Zolk, O.4
Eschenhagen, T.5
-
57
-
-
33745127399
-
Electrical remodeling in atrial fibrillation
-
[quiz 42-3]
-
Dobrev D. Electrical remodeling in atrial fibrillation. Herz 2006, 31:108-112. [quiz 42-3].
-
(2006)
Herz
, vol.31
, pp. 108-112
-
-
Dobrev, D.1
-
58
-
-
50949115126
-
Atrial remodeling and atrial fibrillation: mechanisms and implications
-
Nattel S., Burstein B., Dobrev D. Atrial remodeling and atrial fibrillation: mechanisms and implications. Circ Arrhythm Electrophysiol 2008, 1:62-73.
-
(2008)
Circ Arrhythm Electrophysiol
, vol.1
, pp. 62-73
-
-
Nattel, S.1
Burstein, B.2
Dobrev, D.3
-
59
-
-
84871600649
-
New directions in antiarrhythmic drug therapy for atrial fibrillation
-
Heijman J., Voigt N., Dobrev D. New directions in antiarrhythmic drug therapy for atrial fibrillation. Future Cardiol 2013, 9:71-88.
-
(2013)
Future Cardiol
, vol.9
, pp. 71-88
-
-
Heijman, J.1
Voigt, N.2
Dobrev, D.3
-
60
-
-
5444243754
-
2+ current downregulation in chronic human atrial fibrillation is associated with increased activity of protein phosphatases
-
2+ current downregulation in chronic human atrial fibrillation is associated with increased activity of protein phosphatases. Circulation 2004, 110:2651-2657.
-
(2004)
Circulation
, vol.110
, pp. 2651-2657
-
-
Christ, T.1
Boknik, P.2
Wohrl, S.3
Wettwer, E.4
Graf, E.M.5
Bosch, R.F.6
-
62
-
-
34447645443
-
Pharmacological evidence for altered src kinase regulation of ICa, L in patients with chronic atrial fibrillation
-
Greiser M., Halaszovich C.R., Frechen D., Boknik P., Ravens U., Dobrev D., et al. Pharmacological evidence for altered src kinase regulation of ICa, L in patients with chronic atrial fibrillation. Naunyn Schmiedebergs Arch Pharmacol 2007, 375:383-392.
-
(2007)
Naunyn Schmiedebergs Arch Pharmacol
, vol.375
, pp. 383-392
-
-
Greiser, M.1
Halaszovich, C.R.2
Frechen, D.3
Boknik, P.4
Ravens, U.5
Dobrev, D.6
-
63
-
-
58049166049
-
Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure
-
Yeh Y.H., Wakili R., Qi X.Y., Chartier D., Boknik P., Kaab S., et al. Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure. Circ Arrhythm Electrophysiol 2008, 1:93-102.
-
(2008)
Circ Arrhythm Electrophysiol
, vol.1
, pp. 93-102
-
-
Yeh, Y.H.1
Wakili, R.2
Qi, X.Y.3
Chartier, D.4
Boknik, P.5
Kaab, S.6
-
64
-
-
59149083989
-
Distinct contractile and molecular differences between two goat models of atrial dysfunction: AV block-induced atrial dilatation and atrial fibrillation
-
Greiser M., Neuberger H.R., Harks E., El-Armouche A., Boknik P., de Haan S., et al. Distinct contractile and molecular differences between two goat models of atrial dysfunction: AV block-induced atrial dilatation and atrial fibrillation. J Mol Cell Cardiol 2009, 46:385-394.
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 385-394
-
-
Greiser, M.1
Neuberger, H.R.2
Harks, E.3
El-Armouche, A.4
Boknik, P.5
de Haan, S.6
-
65
-
-
78049496549
-
Multiple potential molecular contributors to atrial hypocontractility caused by atrial tachycardia remodeling in dogs
-
Wakili R., Yeh Y.H., Yan Qi X., Greiser M., Chartier D., Nishida K., et al. Multiple potential molecular contributors to atrial hypocontractility caused by atrial tachycardia remodeling in dogs. Circ Arrhythm Electrophysiol 2010, 3:530-541.
-
(2010)
Circ Arrhythm Electrophysiol
, vol.3
, pp. 530-541
-
-
Wakili, R.1
Yeh, Y.H.2
Yan Qi, X.3
Greiser, M.4
Chartier, D.5
Nishida, K.6
-
66
-
-
11844254718
-
Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A
-
Ai X., Pogwizd S.M. Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A. Circ Res 2005, 96:54-63.
-
(2005)
Circ Res
, vol.96
, pp. 54-63
-
-
Ai, X.1
Pogwizd, S.M.2
-
67
-
-
79958774848
-
Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias
-
Remo B.F., Qu J., Volpicelli F.M., Giovannone S., Shin D., Lader J., et al. Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias. Circ Res 2011, 108:1459-1466.
-
(2011)
Circ Res
, vol.108
, pp. 1459-1466
-
-
Remo, B.F.1
Qu, J.2
Volpicelli, F.M.3
Giovannone, S.4
Shin, D.5
Lader, J.6
-
68
-
-
54449090309
-
Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current
-
Qi X.Y., Yeh Y.H., Xiao L., Burstein B., Maguy A., Chartier D., et al. Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current. Circ Res 2008, 103:845-854.
-
(2008)
Circ Res
, vol.103
, pp. 845-854
-
-
Qi, X.Y.1
Yeh, Y.H.2
Xiao, L.3
Burstein, B.4
Maguy, A.5
Chartier, D.6
-
69
-
-
80054995730
-
Differential protein kinase C isoform regulation and increased constitutive activity of acetylcholine-regulated potassium channels in atrial remodeling
-
Makary S., Voigt N., Maguy A., Wakili R., Nishida K., Harada M., et al. Differential protein kinase C isoform regulation and increased constitutive activity of acetylcholine-regulated potassium channels in atrial remodeling. Circ Res 2011, 109:1031-1043.
-
(2011)
Circ Res
, vol.109
, pp. 1031-1043
-
-
Makary, S.1
Voigt, N.2
Maguy, A.3
Wakili, R.4
Nishida, K.5
Harada, M.6
-
70
-
-
0034640113
-
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
-
Marx S.O., Reiken S., Hisamatsu Y., Jayaraman T., Burkhoff D., Rosemblit N., et al. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 2000, 101:365-376.
-
(2000)
Cell
, vol.101
, pp. 365-376
-
-
Marx, S.O.1
Reiken, S.2
Hisamatsu, Y.3
Jayaraman, T.4
Burkhoff, D.5
Rosemblit, N.6
-
72
-
-
33847728682
-
Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure
-
Lymperopoulos A., Rengo G., Funakoshi H., Eckhart A.D., Koch W.J. Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure. Nat Med 2007, 13:315-323.
-
(2007)
Nat Med
, vol.13
, pp. 315-323
-
-
Lymperopoulos, A.1
Rengo, G.2
Funakoshi, H.3
Eckhart, A.D.4
Koch, W.J.5
-
73
-
-
34447526253
-
Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure
-
El-Armouche A., Pohlmann L., Schlossarek S., Starbatty J., Yeh Y.H., Nattel S., et al. Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure. J Mol Cell Cardiol 2007, 43:223-229.
-
(2007)
J Mol Cell Cardiol
, vol.43
, pp. 223-229
-
-
El-Armouche, A.1
Pohlmann, L.2
Schlossarek, S.3
Starbatty, J.4
Yeh, Y.H.5
Nattel, S.6
-
74
-
-
79960787927
-
Phosphatase-1 inhibitor-1 in physiological and pathological beta-adrenoceptor signalling
-
Wittkopper K., Dobrev D., Eschenhagen T., El-Armouche A. Phosphatase-1 inhibitor-1 in physiological and pathological beta-adrenoceptor signalling. Cardiovasc Res 2011, 91:392-401.
-
(2011)
Cardiovasc Res
, vol.91
, pp. 392-401
-
-
Wittkopper, K.1
Dobrev, D.2
Eschenhagen, T.3
El-Armouche, A.4
-
75
-
-
84859357588
-
Novel molecular targets for atrial fibrillation therapy
-
Dobrev D., Carlsson L., Nattel S. Novel molecular targets for atrial fibrillation therapy. Nat Rev Drug Discov 2012, 11:275-291.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 275-291
-
-
Dobrev, D.1
Carlsson, L.2
Nattel, S.3
-
76
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
Heineke J., Molkentin J.D. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006, 7:589-600.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
77
-
-
32044469687
-
Activation of the calcineurin signaling pathway induces atrial hypertrophy during atrial fibrillation
-
Bukowska A., Lendeckel U., Hirte D., Wolke C., Striggow F., Rohnert P., et al. Activation of the calcineurin signaling pathway induces atrial hypertrophy during atrial fibrillation. Cell Mol Life Sci 2006, 63:333-342.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 333-342
-
-
Bukowska, A.1
Lendeckel, U.2
Hirte, D.3
Wolke, C.4
Striggow, F.5
Rohnert, P.6
-
78
-
-
84871334776
-
CKIP-1 inhibits cardiac hypertrophy by regulating class II histone deacetylase phosphorylation through recruiting PP2A
-
Ling S., Sun Q., Li Y., Zhang L., Zhang P., Wang X., et al. CKIP-1 inhibits cardiac hypertrophy by regulating class II histone deacetylase phosphorylation through recruiting PP2A. Circulation 2012, 126:3028-3040.
-
(2012)
Circulation
, vol.126
, pp. 3028-3040
-
-
Ling, S.1
Sun, Q.2
Li, Y.3
Zhang, L.4
Zhang, P.5
Wang, X.6
-
79
-
-
0036261564
-
Type 1 phosphatase, a negative regulator of cardiac function
-
Carr A.N., Schmidt A.G., Suzuki Y., del Monte F., Sato Y., Lanner C., et al. Type 1 phosphatase, a negative regulator of cardiac function. Mol Cell Biol 2002, 22:4124-4135.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4124-4135
-
-
Carr, A.N.1
Schmidt, A.G.2
Suzuki, Y.3
del Monte, F.4
Sato, Y.5
Lanner, C.6
-
80
-
-
67650710788
-
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology
-
Nicolaou P., Hajjar R.J., Kranias E.G. Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. J Mol Cell Cardiol 2009, 47:365-371.
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 365-371
-
-
Nicolaou, P.1
Hajjar, R.J.2
Kranias, E.G.3
-
81
-
-
56549113103
-
Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy
-
El-Armouche A., Wittkopper K., Degenhardt F., Weinberger F., Didie M., Melnychenko I., et al. Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy. Cardiovasc Res 2008, 80:396-406.
-
(2008)
Cardiovasc Res
, vol.80
, pp. 396-406
-
-
El-Armouche, A.1
Wittkopper, K.2
Degenhardt, F.3
Weinberger, F.4
Didie, M.5
Melnychenko, I.6
-
82
-
-
20244377242
-
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1
-
Pathak A., del Monte F., Zhao W., Schultz J.E., Lorenz J.N., Bodi I., et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circ Res 2005, 96:756-766.
-
(2005)
Circ Res
, vol.96
, pp. 756-766
-
-
Pathak, A.1
del Monte, F.2
Zhao, W.3
Schultz, J.E.4
Lorenz, J.N.5
Bodi, I.6
-
83
-
-
48749116490
-
Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overload
-
Grote-Wessels S., Baba H.A., Boknik P., El-Armouche A., Fabritz L., Gillmann H.J., et al. Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overload. Cardiovasc Res 2008, 79:464-471.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 464-471
-
-
Grote-Wessels, S.1
Baba, H.A.2
Boknik, P.3
El-Armouche, A.4
Fabritz, L.5
Gillmann, H.J.6
-
85
-
-
4644323242
-
Overexpression of the catalytic subunit of protein phosphatase 2A impairs cardiac function
-
Gergs U., Boknik P., Buchwalow I., Fabritz L., Matus M., Justus I., et al. Overexpression of the catalytic subunit of protein phosphatase 2A impairs cardiac function. J Biol Chem 2004, 279:40827-40834.
-
(2004)
J Biol Chem
, vol.279
, pp. 40827-40834
-
-
Gergs, U.1
Boknik, P.2
Buchwalow, I.3
Fabritz, L.4
Matus, M.5
Justus, I.6
-
86
-
-
0033826409
-
Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A
-
Brewis N., Ohst K., Fields K., Rapacciuolo A., Chou D., Bloor C., et al. Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A. Am J Physiol Heart Circ Physiol 2000, 279:H1307-H1318.
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.279
-
-
Brewis, N.1
Ohst, K.2
Fields, K.3
Rapacciuolo, A.4
Chou, D.5
Bloor, C.6
-
87
-
-
66849115406
-
Targeting protein serine/threonine phosphatases for drug development
-
McConnell J.L., Wadzinski B.E. Targeting protein serine/threonine phosphatases for drug development. Mol Pharmacol 2009, 75:1249-1261.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1249-1261
-
-
McConnell, J.L.1
Wadzinski, B.E.2
-
88
-
-
0032535595
-
Identification of the separate domains in the hepatic glycogen-targeting subunit of protein phosphatase 1 that interact with phosphorylase a, glycogen and protein phosphatase 1
-
Armstrong C.G., Doherty M.J., Cohen P.T. Identification of the separate domains in the hepatic glycogen-targeting subunit of protein phosphatase 1 that interact with phosphorylase a, glycogen and protein phosphatase 1. Biochem J 1998, 336(Pt 3):699-704.
-
(1998)
Biochem J
, vol.336
, Issue.PART 3
, pp. 699-704
-
-
Armstrong, C.G.1
Doherty, M.J.2
Cohen, P.T.3
-
89
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata M., Ishizaki T., Satoh H., Ono T., Kawahara T., Morishita T., et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997, 389:990-994.
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
Ono, T.4
Kawahara, T.5
Morishita, T.6
-
90
-
-
85099491079
-
DARPP-32, Jack of all trades... master of which?
-
Yger M., Girault J.A. DARPP-32, Jack of all trades... master of which?. Front Behav Neurosci 2011, 5:56.
-
(2011)
Front Behav Neurosci
, vol.5
, pp. 56
-
-
Yger, M.1
Girault, J.A.2
-
91
-
-
13644256191
-
A selective inhibitor of eIF2α dephosphorylation protects cells from ER stress
-
Boyce M., Bryant K.F., Jousse C., Long K., Harding H.P., Scheuner D., et al. A selective inhibitor of eIF2α dephosphorylation protects cells from ER stress. Science 2005, 307:935-939.
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
-
92
-
-
79953288480
-
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis
-
Tsaytler P., Harding H.P., Ron D., Bertolotti A. Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science 2011, 332:91-94.
-
(2011)
Science
, vol.332
, pp. 91-94
-
-
Tsaytler, P.1
Harding, H.P.2
Ron, D.3
Bertolotti, A.4
-
93
-
-
0035924593
-
Regulation of synaptic strength by protein phosphatase 1
-
Morishita W., Connor J.H., Xia H., Quinlan E.M., Shenolikar S., Malenka R.C. Regulation of synaptic strength by protein phosphatase 1. Neuron 2001, 32:1133-1148.
-
(2001)
Neuron
, vol.32
, pp. 1133-1148
-
-
Morishita, W.1
Connor, J.H.2
Xia, H.3
Quinlan, E.M.4
Shenolikar, S.5
Malenka, R.C.6
-
94
-
-
33845611066
-
Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy
-
Yamada M., Ikeda Y., Yano M., Yoshimura K., Nishino S., Aoyama H., et al. Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy. FASEB J 2006, 20:1197-1199.
-
(2006)
FASEB J
, vol.20
, pp. 1197-1199
-
-
Yamada, M.1
Ikeda, Y.2
Yano, M.3
Yoshimura, K.4
Nishino, S.5
Aoyama, H.6
-
95
-
-
84860431545
-
Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling
-
Miyazaki Y., Ikeda Y., Shiraishi K., Fujimoto S.N., Aoyama H., Yoshimura K., et al. Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling. PLoS One 2012, 7:e35875.
-
(2012)
PLoS One
, vol.7
-
-
Miyazaki, Y.1
Ikeda, Y.2
Shiraishi, K.3
Fujimoto, S.N.4
Aoyama, H.5
Yoshimura, K.6
-
96
-
-
84877284455
-
AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling
-
Fish K.M., Ladage D., Kawase Y., Karakikes I., Jeong D., Ly H., et al. AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling. Circ Heart Fail 2013, 6:310-317.
-
(2013)
Circ Heart Fail
, vol.6
, pp. 310-317
-
-
Fish, K.M.1
Ladage, D.2
Kawase, Y.3
Karakikes, I.4
Jeong, D.5
Ly, H.6
|