Identification of AKAP79 as a protein phosphatase 1 catalytic binding protein

Biochemistry

Volumn 50, Issue 23, 2011, Pages 5279-5291

  Le, Andrew V ^a   Tavalin, Steven J ^b   Dodge Kafka, Kimberly L ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING MOTIF; BINDING PROTEINS; CATALYTIC SUBUNITS; CELLULAR PROCESS; DEPHOSPHORYLATIONS; DIRECT INTERACTIONS; INTERACTION DOMAIN; PHOSPHATASE ACTIVITY; PROTEIN PHOSPHATASE-1; PULLDOWN ASSAYS; PURIFIED PROTEIN; RAT BRAIN; REGULATORY SUBUNITS; SPECIFIC LOCATION; SUBSTRATE SPECIFICITY;

AMINO ACIDS; CATALYST ACTIVITY; COMPLEXATION; PHOSPHATASES; PURIFICATION; SURFACE PLASMON RESONANCE;

PROTEINS;

BINDING PROTEIN; CALMODULIN; PEPTIDOMIMETIC AGENT; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 1 BINDING PROTEIN; PROTEIN AKAP79; PROTEIN KINASE C; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; IC 50; IMMUNOPRECIPITATION; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN MOTIF; RAT; SURFACE PLASMON RESONANCE;

A KINASE ANCHOR PROTEINS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATALYSIS; CELLS, CULTURED; MOLECULAR SEQUENCE DATA; PROTEIN PHOSPHATASE 1; PROTEIN STRUCTURE, TERTIARY; RATS; SURFACE PLASMON RESONANCE;

RATTUS;

EID: 79958848133     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200089z     Document Type: Article

References (39)

1. Shenolikar, S. and Nairn, A. C. (1991) Protein phosphatases: recent progress Adv. Second Messenger Phosphoprotein Res. 23, 1-121
2. Shenolikar, S. (1994) Protein serine/threonine phosphatases-new avenues for cell regulation Annu. Rev. Cell Biol. 10, 55-86 (Pubitemid 24372816)
3. Aggen, J. B., Nairn, A. C., and Chamberlin, R. (2000) Regulation of protein phosphatase-1 Chem. Biol. 7, R13-23
4. Virshup, D. M. and Shenolikar, S. (2009) From promiscuity to precision: protein phosphatases get a makeover Mol. Cell 33, 537-545
5. Bollen, M. (2001) Combinatorial control of protein phosphatase-1 Trends Biochem. Sci. 26, 426-431 (Pubitemid 32607484)
6. Cohen, P. T. (2002) Protein phosphatase 1 - targeted in many directions J. Cell Sci. 115, 241-256 (Pubitemid 34145174)
7. Doherty, M. J., Moorhead, G., Morrice, N., Cohen, P., and Cohen, P. T. (1995) Amino acid sequence and expression of the hepatic glycogen-binding (GL)-subunit of protein phosphatase-1 FEBS Lett. 375, 294-298
8. Hsieh-Wilson, L. C., Allen, P. B., Watanabe, T., Nairn, A. C., and Greengard, P. (1999) Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1 Biochemistry 38, 4365-4373
9. McAvoy, T., Allen, P. B., Obaishi, H., Nakanishi, H., Takai, Y., Greengard, P., Nairn, A. C., and Hemmings, H. C., Jr. (1999) Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation Biochemistry 38, 12943-12949
10. Kreivi, J. P., Trinkle-Mulcahy, L., Lyon, C. E., Morrice, N. A., Cohen, P., and Lamond, A. I. (1997) Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity FEBS Lett. 420, 57-62 (Pubitemid 28037200)
11. Hendrickx, A., Beullens, M., Ceulemans, H., Den Abt, T., Van Eynde, A., Nicolaescu, E., Lesage, B., and Bollen, M. (2009) Docking motif-guided mapping of the interactome of protein phosphatase-1 Chem. Biol. 16, 365-371
12. Ayllon, V., Cayla, X., Garcia, A., Fleischer, A., and Rebollo, A. (2002) Protein phosphatase 1 interacts wtih protein required for meiosis and other cellular processes in Saccharomyces cerevisiae Mol. Cell. Biol. 16, 4199-4206
13. Huang, H.-B., Horiuchi, A., Watanabe, T., Shih, S. R., Tsay, H. J., Li, H. C., Greengard, P., and Nairn, A. C. (1999) Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2 J. Biol. Chem. 274, 7870-7878
14. Yan, Z., Hsieh-Wilson, L., Feng, J., Tomizawa, K., Allen, P. B., Fienberg, A. A., Nairn, A. C., and Greengard, P. (1999) Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin Nature Neurosci. 2, 13-17 (Pubitemid 30488934)
15. Ragusa, M. J., Dancheck, B., Critton, D. A., Nairn, A. C., Page, R., and Peti, W. (2010) Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites Nat. Struct. Mol. Biol. 17, 459-464
16. Connor, J. H., Weiser, D. C., Li, S., Hallenbeck, J. M., and Shenolikar, S. (2001) Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1 Mol. Cell Biol. 21, 6841-6850 (Pubitemid 32911245)
17. Bauman, A. L. and Scott, J. D. (2002) Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo Nat. Cell Biol. 4, E203-206
18. Westphal, R. S., Tavalin, S. J., Lin, J. W., Alto, N. M., Fraser, I. D., Langeberg, L. K., Sheng, M., and Scott, J. D. (1999) Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex Science 285, 93-96 (Pubitemid 29307572)
19. Colledge, M., Dean, R. A., Scott, G. K., Langeberg, L. K., Huganir, R. L., and Scott, J. D. (2000) Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex Neuron 27, 107-119
20. Coghlan, V. M., Perrino, B. A., Howard, M., Langeberg, L. K., Hicks, J. B., Gallatin, W. M., and Scott, J. D. (1995) Association of protein kinase A and protein phosphatase 2B with a common anchoring protein Science 267, 108-111
21. Klauck., T, M., Faux, M. C., Labudda, K., Langeberg, L. K., Jaken, S., and Scott, J. D. (1996) Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein Science 271, 1589-1592 (Pubitemid 26097218)
22. Beullens, M., Van Eynde, A., Vulsteke, V., Connor, J., Shenolikar, S., Stalmans, W., and Bollen, M. (1999) Molecular determinants of nuclear protein phosphatase-1 regulation by NIPP-1 J. Biol. Chem. 274, 14053-14061
23. Schillace, R. V. and Scott, J. D. (1999) Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220 Curr. Biol. 9, 321-324 (Pubitemid 29181839)
24. Zhang, J., Vinuela, A., Neely, M. H., Hallett, P. J., Grant, S. G., Miller, G. M., Isacson, O., Caron, M. G., and Yao, W. D. (2007) Inhibition of the dopamine D1 receptor signaling by PSD-95 J. Biol. Chem. 282, 15778-15789 (Pubitemid 47093305)
25. Dodge, K. and Scott, J. D. (2000) AKAP79 and the evolution of the AKAP model FEBS Lett. 476, 58-61 (Pubitemid 30394651)
26. Connor, J. H., Kleeman, T., Barik, S., Honkanen, R. E., and Shenolikar, S. (1999) Importance of the beta12-beta13 loop in protein phosphatase-1 catalytic subunit for inhibition by toxins and mammalian protein inhibitors J. Biol. Chem. 274, 22366-22372
27. Schillace, R. V., Voltz, J. W., Sim, A. T., Shenolikar, S., and Scott, J. D. (2001) Multiple interactions within the AKAP220 signaling complex contribute to protein phosphatase 1 regulation J. Biol. Chem. 276, 12128-12134
28. Steen, R., Beullens, M., Landsverk, H. B., Bollen, M., and Collas, P. (2003) AKAP149 is a novel PP1 specificier required to maintain nuclear envelope integrity in G1 phase J. Cell Sci. 116, 2237-2246 (Pubitemid 36722370)
29. Bollen, M., Peti, W., Ragusa, M. J., and Beullens, M. (2010) The extended PP1 toolkit: designed to create specificity Trends Biochem. Sci. 35, 450-458
30. Faux, M. C. and Scott, J. D. (1997) Regulation of the AKAP79-protein kinase C interaction by Ca2+/Calmodulin J. Biol. Chem. 272, 17038-17044 (Pubitemid 27289810)
31. Brooks, I. M. and Tavalin, S. J. CaMKII inhibitors disrupt AKAP79-dependent PKC signaling to GluA1 AMPA receptors. J. Biol. Chem. 2010, in press.
32. Nikandrova, Y. A., Jiao, Y., Baucum, A. J., Tavalin, S. J., and Colbran, R. J. (2010) Ca2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor (AMPAR) activity J. Biol. Chem. 285, 923-934
33. Dell'Acqua, M. L., Dodge, K. L., Tavalin, S. J., and Scott, J. D. (2002) Mapping the protein phosphatase-2B anchoring site on AKAP79. Binding and inhibition of phosphatase activity are mediated by residues 315-360 J. Biol. Chem. 277, 48796-48802 (Pubitemid 35470846)
34. Ragusa, M. J., Dancheck, B., Critton, D. A., Nairn, A. C., Page, R., and Peti, W. (2010) Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites Nat. Struct. Mol. Biol. 17, 459-464
35. Dell'Acqua, M. L., Smith, K. E., Gorski, J. A., Horne, E. A., Gibson, E. S., and Gomez, L. L. (2006) Regulation of neuronal PKA signaling through AKAP targeting dynamics Eur. J. Cell Biol. 85, 627-633 (Pubitemid 43863036)
36. Kim, M. J., Futai, K., Jo, J., Hayashi, Y., Cho, K., and Sheng, M. (2007) Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95 Neuron 56, 488-502 (Pubitemid 350026266)
37. Sabio, G., Reuver, S., Feijoo, C., Hasegawa, M., Thomas, G. M., Centeno, F., Kuhlendahl, S., Leal-Ortiz, S., Goedert, M., Garner, C., and Cuenda, A. (2004) Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2 Biochem. J. 380, 19-30 (Pubitemid 38725725)
38. Gardoni, F., Polli, F., Cattabeni, F., and Di Luca, M. (2006) Calcium-calmodulin-dependent protein kinase II phosphorylation modulates PSD-95 Eur. J. Neurosci. 24, 2694-2704 (Pubitemid 44813821)
39. Tavalin, S. J., Colledge, M., Hell, J. W., Langeberg, L. K., Huganir, R. L., and Scott, J. D. (2002) Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression J. Neurosci. 22, 3044-3051 (Pubitemid 35379193)