DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through notch hyper-activation

Oncotarget

Volumn 6, Issue 26, 2015, Pages 22467-22479

  Faronato, Monica ^a   Nguyen, Van T M ^a   Patten, Darren K ^a   Lombardo, Ylenia ^a   Steel, Jennifer H ^a   Patel, Naina ^a   Woodley, Laura ^a   Shousha, Sami ^a   Pruneri, Giancarlo ^b   Charles Coombes, R ^a   Magnani, Luca ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

Breast cancer; DMXL2; EMT; Endocrine therapy; Notch

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DMXL2 PROTEIN; MEMBRANE PROTEIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; PROTEIN ZO1; UNCLASSIFIED DRUG; UVOMORULIN; V ADENOSINE TRIPHOSPHATASE; CHROMATIN; DMXL2 PROTEIN, HUMAN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA, HUMAN; NERVE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; CARCINOGENESIS; CELL INVASION; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN ASSEMBLY; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION; BIOSYNTHESIS; BREAST TUMOR; CELL MOTION; CHROMATIN; FEMALE; GENETICS; MCF-7 CELL LINE; METABOLISM; METASTASIS; PATHOLOGY; PHYSIOLOGY; TISSUE MICROARRAY; TUMOR CELL LINE; TUMOR INVASION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHROMATIN; EPITHELIAL-MESENCHYMAL TRANSITION; ESTROGEN RECEPTOR ALPHA; FEMALE; HUMANS; MCF-7 CELLS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NERVE TISSUE PROTEINS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TISSUE ARRAY ANALYSIS;

EID: 84941243537     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4164     Document Type: Article

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