-
1
-
-
84872967522
-
Cancer statistics, 2013
-
Siegel, R.; Naishadham, D.; Jemal, A. Cancer statistics, 2013. CA Cancer J. Clin. 2013, 63, 11-30.
-
(2013)
CA Cancer J. Clin.
, vol.63
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
79955460636
-
Notch signalling in solid tumours: A little bit of everything but not all the time
-
Ranganathan, P.; Weaver, K. L.; Capobianco, A. J. Notch signalling in solid tumours: a little bit of everything but not all the time. Nat. Rev. Cancer 2011, 11, 338-351.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 338-351
-
-
Ranganathan, P.1
Weaver, K.L.2
Capobianco, A.J.3
-
3
-
-
78650510609
-
mTOR: From growth signal integration to cancer, diabetes and ageing
-
Zoncu, R.; Efeyan, A.; Sabatini, D. M. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 2011, 12, 21-35.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
4
-
-
80955181031
-
The Hedgehog's tale: Developing strategies for targeting cancer
-
Ng, J. M.; Curran, T. The Hedgehog's tale: developing strategies for targeting cancer. Nat. Rev. Cancer 2011, 11, 493-501.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 493-501
-
-
Ng, J.M.1
Curran, T.2
-
5
-
-
84860217431
-
The functions and regulation of the PTEN tumour suppressor
-
Song, M. S.; Salmena, L.; Pandolfi, P. P. The functions and regulation of the PTEN tumour suppressor. Nat. Rev. Mol. Cell Biol. 2012, 13, 283-296.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 283-296
-
-
Song, M.S.1
Salmena, L.2
Pandolfi, P.P.3
-
6
-
-
68249093818
-
Targeting the phosphoinositide 3-kinase pathway in cancer
-
Liu, P.; Cheng, H.; Roberts, T. M.; Zhao, J. J. Targeting the phosphoinositide 3-kinase pathway in cancer. Nat. Rev. Drug Discov. 2009, 8, 627-644.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 627-644
-
-
Liu, P.1
Cheng, H.2
Roberts, T.M.3
Zhao, J.J.4
-
7
-
-
42549164807
-
Wnt signalling and its impact on development and cancer
-
Klaus, A.; Birchmeier, W. Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer 2008, 8, 387-398.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 387-398
-
-
Klaus, A.1
Birchmeier, W.2
-
8
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
-
Radtke, F.; Raj, K. The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat. Rev. Cancer 2003, 3, 756-767.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
9
-
-
77953523118
-
The role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressiveness
-
Wang, Z.; Li, Y.; Kong, D.; Sarkar, F. H. The role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressiveness. Curr. Drug Targets 2010, 11, 745-751.
-
(2010)
Curr. Drug Targets
, vol.11
, pp. 745-751
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Sarkar, F.H.4
-
10
-
-
13244298117
-
Notch and epithelial-mesenchyme transition in development and tumor progression: Another turn of the screw
-
Grego-Bessa, J.; Diez, J.; Timmerman, L.; de, la. Pompa. J. L. Notch and epithelial-mesenchyme transition in development and tumor progression: another turn of the screw. Cell Cycle 2004, 3, 718-721.
-
(2004)
Cell Cycle
, vol.3
, pp. 718-721
-
-
Grego-Bessa, J.1
Diez, J.2
Timmerman, L.3
de la Pompa, J.L.4
-
11
-
-
78649466892
-
Targeting Notch signaling pathway to overcome drug resistance for cancer therapy
-
Wang, Z.; Li, Y.; Ahmad, A.; Azmi, A. S.; Banerjee, S.; Kong, D.; Sarkar, F.H. Targeting Notch signaling pathway to overcome drug resistance for cancer therapy. Biochim. Biophys. Acta 2010, 1806, 258-267.
-
(2010)
Biochim. Biophys. Acta
, vol.1806
, pp. 258-267
-
-
Wang, Z.1
Li, Y.2
Ahmad, A.3
Azmi, A.S.4
Banerjee, S.5
Kong, D.6
Sarkar, F.H.7
-
12
-
-
58149174376
-
Exploitation of the Notch signaling pathway as a novel target for cancer therapy
-
Wang, Z.; Li, Y.; Banerjee, S.; Sarkar, F. H. Exploitation of the Notch signaling pathway as a novel target for cancer therapy. Anticancer Res. 2008, 28, 3621-3630.
-
(2008)
Anticancer Res.
, vol.28
, pp. 3621-3630
-
-
Wang, Z.1
Li, Y.2
Banerjee, S.3
Sarkar, F.H.4
-
13
-
-
67349193226
-
Emerging role of Notch in stem cells and cancer
-
Wang, Z.; Li, Y.; Banerjee, S.; Sarkar, F. H. Emerging role of Notch in stem cells and cancer. Cancer Lett. 2009, 279, 8-12.
-
(2009)
Cancer Lett.
, vol.279
, pp. 8-12
-
-
Wang, Z.1
Li, Y.2
Banerjee, S.3
Sarkar, F.H.4
-
14
-
-
77951884078
-
Cross-talk between miRNA and Notch signaling pathways in tumor development and progression
-
Wang, Z.; Li, Y.; Kong, D.; Ahmad, A.; Banerjee, S.; Sarkar, F. H. Cross-talk between miRNA and Notch signaling pathways in tumor development and progression. Cancer Lett. 2010, 292, 141-148.
-
(2010)
Cancer Lett.
, vol.292
, pp. 141-148
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Ahmad, A.4
Banerjee, S.5
Sarkar, F.H.6
-
15
-
-
77953700950
-
Targeting Notch to target cancer stem cells
-
Pannuti, A.; Foreman, K.; Rizzo, P.; Osipo, C.; Golde, T.; Osborne, B.; Miele, L. Targeting Notch to target cancer stem cells. Clin. Cancer Res. 2010, 16, 3141-3152.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 3141-3152
-
-
Pannuti, A.1
Foreman, K.2
Rizzo, P.3
Osipo, C.4
Golde, T.5
Osborne, B.6
Miele, L.7
-
16
-
-
50849111710
-
Rational targeting of Notch signaling in cancer
-
Rizzo, P.; Osipo, C.; Foreman, K.; Golde, T.; Osborne, B.; Miele, L. Rational targeting of Notch signaling in cancer. Oncogene 2008, 27, 5124-5131.
-
(2008)
Oncogene
, vol.27
, pp. 5124-5131
-
-
Rizzo, P.1
Osipo, C.2
Foreman, K.3
Golde, T.4
Osborne, B.5
Miele, L.6
-
17
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan, R.; Ilagan, M. X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009, 137, 216-233.
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
18
-
-
33644752839
-
Notch signaling
-
Miele, L. Notch signaling. Clin. Cancer Res. 2006, 12, 1074-1079.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 1074-1079
-
-
Miele, L.1
-
19
-
-
84870954822
-
Epigenetic silencing of Notch signaling in gastrointestinal cancers
-
Piazzi, G.; Bazzoli, F.; Ricciardiello, L. Epigenetic silencing of Notch signaling in gastrointestinal cancers. Cell Cycle 2012, 11, 4323-4327.
-
(2012)
Cell Cycle
, vol.11
, pp. 4323-4327
-
-
Piazzi, G.1
Bazzoli, F.2
Ricciardiello, L.3
-
21
-
-
84859499532
-
Notch signaling and brain tumors
-
Stockhausen, M. T.; Kristoffersen, K.; Poulsen, H. S. Notch signaling and brain tumors. Adv. Exp. Med. Biol. 2012, 727, 289-304.
-
(2012)
Adv. Exp. Med. Biol.
, vol.727
, pp. 289-304
-
-
Stockhausen, M.T.1
Kristoffersen, K.2
Poulsen, H.S.3
-
22
-
-
84859482643
-
Notch signaling and intestinal cancer
-
Guilmeau, S. Notch signaling and intestinal cancer. Adv. Exp. Med. Biol. 2012, 727, 272-288.
-
(2012)
Adv. Exp. Med. Biol.
, vol.727
, pp. 272-288
-
-
Guilmeau, S.1
-
23
-
-
84859484455
-
Notch-signaling and nonmelanoma skin cancer: An ancient friend, revisited
-
Reichrath, J; Reichrath, S. Notch-signaling and nonmelanoma skin cancer: an ancient friend, revisited. Adv. Exp. Med. Biol. 2012, 727, 265-271.
-
(2012)
Adv. Exp. Med. Biol.
, vol.727
, pp. 265-271
-
-
Reichrath, J.1
Reichrath, S.2
-
24
-
-
84859506935
-
Notch signaling and malignant melanoma
-
Muller, C. S. Notch signaling and malignant melanoma. Adv. Exp. Med. Biol. 2012, 727, 258-264.
-
(2012)
Adv. Exp. Med. Biol.
, vol.727
, pp. 258-264
-
-
Muller, C.S.1
-
25
-
-
84859482094
-
Notch signaling and breast cancer
-
Reedijk, M. Notch signaling and breast cancer. Adv. Exp. Med. Biol. 2012, 727, 241-257.
-
(2012)
Adv. Exp. Med. Biol.
, vol.727
, pp. 241-257
-
-
Reedijk, M.1
-
26
-
-
78951481235
-
Role of Notch and its oncogenic signaling crosstalk in breast cancer
-
Guo, S.; Liu, M.; Gonzalez-Perez, R. R. Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim. Biophys. Acta. 2011, 1815, 197-213.
-
(2011)
Biochim. Biophys. Acta.
, vol.1815
, pp. 197-213
-
-
Guo, S.1
Liu, M.2
Gonzalez-Perez, R.R.3
-
27
-
-
84856008970
-
Notch signalling in cancer progression and bone metastasis
-
Sethi, N.; Kang, Y. Notch signalling in cancer progression and bone metastasis. Br. J. Cancer 2011, 105, 1805-1810.
-
(2011)
Br. J. Cancer
, vol.105
, pp. 1805-1810
-
-
Sethi, N.1
Kang, Y.2
-
28
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De, Craene. B.; Berx, G. Regulatory networks defining EMT during cancer initiation and progression. Nat. Rev. Cancer 2013, 13, 97-110.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 97-110
-
-
De, C.B.1
Berx, G.2
-
29
-
-
70450198396
-
Epithelialmesenchymal transitions in development and disease
-
Thiery, J. P.; Acloque, H.; Huang, R. Y.; Nieto, M. A. Epithelialmesenchymal transitions in development and disease. Cell 2009, 139, 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
30
-
-
84878905949
-
Emerging roles of PDGF-D in EMT progression during tumorigenesis
-
Wu, Q.; Hou, X.; Xia, J.; Qian, X.; Miele, L.; Sarkar, F. H.; Wang, Z. Emerging roles of PDGF-D in EMT progression during tumorigenesis. Cancer Treat. Rev. 2013, 39, 640-646.
-
(2013)
Cancer Treat. Rev.
, vol.39
, pp. 640-646
-
-
Wu, Q.1
Hou, X.2
Xia, J.3
Qian, X.4
Miele, L.5
Sarkar, F.H.6
Wang, Z.7
-
31
-
-
4043052971
-
Epithelial-mesenchymal transitions: Twist in development and metastasis
-
Kang, Y.; Massague, J. Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 2004, 118, 277-279.
-
(2004)
Cell
, vol.118
, pp. 277-279
-
-
Kang, Y.1
Massague, J.2
-
32
-
-
77957571588
-
The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer
-
Sarkar, F. H.; Li, Y.; Wang, Z.; Kong, D. The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer. Cancer Metastasis Rev. 2010, 29, 383-394.
-
(2010)
Cancer Metastasis Rev.
, vol.29
, pp. 383-394
-
-
Sarkar, F.H.1
Li, Y.2
Wang, Z.3
Kong, D.4
-
33
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
Rhim, A. D.; Mirek, E. T.; Aiello, N. M.; Maitra A.; Bailey, J. M.; McAllister, F.; Reichert, M.; Beatty, G. L.; Rustgi, A. K.; Vonderheide, R. H.; Leach, S. D.; Stanger, B. Z. EMT and dissemination precede pancreatic tumor formation. Cell 2012, 148, 349-361.
-
(2012)
Cell
, vol.148
, pp. 349-361
-
-
Rhim, A.D.1
Mirek, E.T.2
Aiello, N.M.3
Maitra, A.4
Bailey, J.M.5
McAllister, F.6
Reichert, M.7
Beatty, G.L.8
Rustgi, A.K.9
Vonderheide, R.H.10
Leach, S.D.11
Stanger, B.Z.12
-
34
-
-
65549141305
-
Acquisition of epithelial-mesenchymal transition phenotype of gemcitabineresistant pancreatic cancer.;ells is linked with activation of the notch signaling pathway
-
Wang, Z.; Li, Y.; Kong, D.; Banerjee, S.; Ahmad, A.; Azmi, A. S.; Ali, S.; Abbruzzese, J. L.; Gallick, G. E.; Sarkar, F. H. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabineresistant pancreatic cancer.;ells is linked with activation of the notch signaling pathway. Cancer Res. 2009, 69, 2400-2407.
-
(2009)
Cancer Res.
, vol.69
, pp. 2400-2407
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Banerjee, S.4
Ahmad, A.5
Azmi, A.S.6
Ali, S.7
Abbruzzese, J.L.8
Gallick, G.E.9
Sarkar, F.H.10
-
35
-
-
84859095585
-
Activation of Notch-1 enhances epithelialmesenchymal transition in gefitinib-acquired resistant lung cancer cells
-
Xie, M.; Zhang, L.; He, C. S.; Xu, F.; Liu, J. L.; Hu, Z. H.; Zhao, L. P.; Tian, Y. Activation of Notch-1 enhances epithelialmesenchymal transition in gefitinib-acquired resistant lung cancer cells. J. Cell. Biochem. 2012, 113, 1501-1513.
-
(2012)
J. Cell. Biochem.
, vol.113
, pp. 1501-1513
-
-
Xie, M.1
Zhang, L.2
He, C.S.3
Xu, F.4
Liu, J.L.5
Hu, Z.H.6
Zhao, L.P.7
Tian, Y.8
-
36
-
-
79151479321
-
Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-kappaB signaling pathways
-
Ahmad, A.; Wang, Z.; Kong, D.; Ali, R.; Ali, S.; Banerjee, S.; Sarkar, F. H. Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-kappaB signaling pathways. Breast Cancer Res, Treat. 2011, 126, 15-25.
-
(2011)
Breast Cancer Res, Treat.
, vol.126
, pp. 15-25
-
-
Ahmad, A.1
Wang, Z.2
Kong, D.3
Ali, R.4
Ali, S.5
Banerjee, S.6
Sarkar, F.H.7
-
37
-
-
48649098427
-
Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells
-
Kong, D.; Wang, Z.; Sarkar, S. H.; Li, Y.; Banerjee, S.; Saliganan, A.; Kim, H. R.; Cher, M. L.; Sarkar, F. H. Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells. Stem Cells 2008, 26, 1425-1435.
-
(2008)
Stem Cells
, vol.26
, pp. 1425-1435
-
-
Kong, D.1
Wang, Z.2
Sarkar, S.H.3
Li, Y.4
Banerjee, S.5
Saliganan, A.6
Kim, H.R.7
Cher, M.L.8
Sarkar, F.H.9
-
38
-
-
79957487931
-
Notch-1 induces epithelialmesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
-
Bao, B.; Wang, Z.; Ali, S.; Kong, D.; Li, Y.; Ahmad, A.; Banerjee, S.; Azmi, A. S.; Miele, L.; Sarkar, F. H. Notch-1 induces epithelialmesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett. 2011, 307, 26-36.
-
(2011)
Cancer Lett.
, vol.307
, pp. 26-36
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
Kong, D.4
Li, Y.5
Ahmad, A.6
Banerjee, S.7
Azmi, A.S.8
Miele, L.9
Sarkar, F.H.10
-
39
-
-
36349006961
-
Development and characterization of gemcitabineresistant pancreatic tumor cells
-
Shah, A. N.; Summy, J. M.; Zhang, J.; Park, S. I.; Parikh, N. U.; Gallick, G. E. Development and characterization of gemcitabineresistant pancreatic tumor cells. Ann. Surg. Oncol. 2007, 14, 3629-3637.
-
(2007)
Ann. Surg. Oncol.
, vol.14
, pp. 3629-3637
-
-
Shah, A.N.1
Summy, J.M.2
Zhang, J.3
Park, S.I.4
Parikh, N.U.5
Gallick, G.E.6
-
40
-
-
84860006878
-
Immunohistochemical study of the epithelialmesenchymal transition phenotype in cancer of unknown primary: Incidence, correlations and prognostic utility
-
Stoyianni, A.; Goussia, A.; Pentheroudakis, G.; Siozopoulou, V.; Ioachim, E.; Krikelis, D.; Golfinopoulos, V.; Cervantes, A.; Bobos, M.; Fotsis, T.; Bellou, S.; Fountzilas, G.; Malamou-Mitsi, V.; Pavlidis, N. Immunohistochemical study of the epithelialmesenchymal transition phenotype in cancer of unknown primary: incidence, correlations and prognostic utility. Anticancer Res. 2012, 32, 1273-1281.
-
(2012)
Anticancer Res.
, vol.32
, pp. 1273-1281
-
-
Stoyianni, A.1
Goussia, A.2
Pentheroudakis, G.3
Siozopoulou, V.4
Ioachim, E.5
Krikelis, D.6
Golfinopoulos, V.7
Cervantes, A.8
Bobos, M.9
Fotsis, T.10
Bellou, S.11
Fountzilas, G.12
Malamou-Mitsi, V.13
Pavlidis, N.14
-
41
-
-
45849139695
-
Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes
-
Huang, Y.; Hoque, M. O.; Wu, F.; Trink, B.; Sidransky, D.; Ratovitski, E. A. Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes. Cell Cycle 2008, 7, 1613-1622.
-
(2008)
Cell Cycle
, vol.7
, pp. 1613-1622
-
-
Huang, Y.1
Hoque, M.O.2
Wu, F.3
Trink, B.4
Sidransky, D.5
Ratovitski, E.A.6
-
42
-
-
79960385475
-
Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer
-
Gungor, C.; Zander, H.; Effenberger, K. E.; Vashist, Y. K.; Kalinina, T.; Izbicki, J. R.; Yekebas, E.; Bockhorn, M. Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer. Cancer Res. 2011, 71, 5009-5019.
-
(2011)
Cancer Res.
, vol.71
, pp. 5009-5019
-
-
Gungor, C.1
Zander, H.2
Effenberger, K.E.3
Vashist, Y.K.4
Kalinina, T.5
Izbicki, J.R.6
Yekebas, E.7
Bockhorn, M.8
-
43
-
-
84859270591
-
Notch signaling mediates TGF-beta1-induced epithelialmesenchymal transition through the induction of Snai1
-
Matsuno, Y.; Coelho, A. L.; Jarai, G.; Westwick, J.; Hogaboam, C. M. Notch signaling mediates TGF-beta1-induced epithelialmesenchymal transition through the induction of Snai1. Int. J. Biochem. Cell Biol. 2012, 44, 776-789.
-
(2012)
Int. J. Biochem. Cell Biol.
, vol.44
, pp. 776-789
-
-
Matsuno, Y.1
Coelho, A.L.2
Jarai, G.3
Westwick, J.4
Hogaboam, C.M.5
-
44
-
-
84867068023
-
Inhibition of Notch signaling by a gamma-secretase inhibitor attenuates hepatic fibrosis in rats
-
Chen, Y.; Zheng, S.; Qi, D.; Zheng, S.; Guo, J.; Zhang, S.; Weng, Z. Inhibition of Notch signaling by a gamma-secretase inhibitor attenuates hepatic fibrosis in rats. PLoS One 2012, 7, e46512.
-
(2012)
PLoS One
, vol.7
-
-
Chen, Y.1
Zheng, S.2
Qi, D.3
Zheng, S.4
Guo, J.5
Zhang, S.6
Weng, Z.7
-
45
-
-
84879106039
-
Notch3 induces epithelial-mesenchymal transition and attenuates carboplatin-induced apoptosis in ovarian cancer cells
-
Gupta, N.; Xu, Z.; El-Sehemy, A.; Steed, H.; Fu, Y. Notch3 induces epithelial-mesenchymal transition and attenuates carboplatin-induced apoptosis in ovarian cancer cells. Gynecol. Oncol. 2013.
-
(2013)
Gynecol. Oncol.
-
-
Gupta, N.1
Xu, Z.2
El-Sehemy, A.3
Steed, H.4
Fu, Y.5
-
46
-
-
80155126639
-
A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors
-
Ohashi, S.; Natsuizaka, M.; Naganuma, S.; Kagawa, S.; Kimura, S.; Itoh, H.; Kalman, R. A.; Nakagawa, M.; Darling, D. S.; Basu, D.; Gimotty, P. A.; Klein-Szanto, A. J.; Diehl, J. A.; Herlyn, M.; Nakagawa, H. A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors. Cancer Res. 2011, 71, 6836-6847.
-
(2011)
Cancer Res.
, vol.71
, pp. 6836-6847
-
-
Ohashi, S.1
Natsuizaka, M.2
Naganuma, S.3
Kagawa, S.4
Kimura, S.5
Itoh, H.6
Kalman, R.A.7
Nakagawa, M.8
Darling, D.S.9
Basu, D.10
Gimotty, P.A.11
Klein-Szanto, A.J.12
Diehl, J.A.13
Herlyn, M.14
Nakagawa, H.15
-
47
-
-
23744483487
-
Snailregulated genes in malignant melanoma
-
Kuphal, S.; Palm, H. G.; Poser, I.; Bosserhoff, A. K. Snailregulated genes in malignant melanoma. Melanoma Res. 2005, 15, 305-313.
-
(2005)
Melanoma Res.
, vol.15
, pp. 305-313
-
-
Kuphal, S.1
Palm, H.G.2
Poser, I.3
Bosserhoff, A.K.4
-
48
-
-
19644364477
-
Proteotypic classification of spontaneous and transgenic mammary neoplasms
-
Mikaelian, I.; Blades, N.; Churchill, G. A.; Fancher, K.; Knowles, B. B.; Eppig, J. T.; Sundberg, J. P. Proteotypic classification of spontaneous and transgenic mammary neoplasms. Breast Cancer Res. 2004, 6, R668-R679.
-
(2004)
Breast Cancer Res.
, vol.6
-
-
Mikaelian, I.1
Blades, N.2
Churchill, G.A.3
Fancher, K.4
Knowles, B.B.5
Eppig, J.T.6
Sundberg, J.P.7
-
49
-
-
84872869354
-
Delta like ligand 4 induces impaired chemo-drug delivery and enhanced chemoresistance in pancreatic cancer
-
Kang, M.; Jiang. B.; Xu, B.; Lu, W.; Guo, Q.; Xie, Q.; Zhang, B.; Dong, X.; Chen, D.; Wu, Y. Delta like ligand 4 induces impaired chemo-drug delivery and enhanced chemoresistance in pancreatic cancer. Cancer Lett. 2013, 330, 11-21.
-
(2013)
Cancer Lett.
, vol.330
, pp. 11-21
-
-
Kang, M.1
Jiang, B.2
Xu, B.3
Lu, W.4
Guo, Q.5
Xie, Q.6
Zhang, B.7
Dong, X.8
Chen, D.9
Wu, Y.10
-
50
-
-
1842524153
-
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-tomesenchymal transition
-
Zavadil, J.; Cermak, L.; Soto-Nieves, N.; Bottinger, E. P. Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-tomesenchymal transition. EMBO J. 2004, 23, 1155-1165.
-
(2004)
EMBO J.
, vol.23
, pp. 1155-1165
-
-
Zavadil, J.1
Cermak, L.2
Soto-Nieves, N.3
Bottinger, E.P.4
-
51
-
-
77957790485
-
Jagged/Notch signalling is required for a subset of TGFbeta1 responses in human kidney epithelial cells
-
Nyhan, K. C.; Faherty, N.; Murray, G.; Cooey, L. B.; Godson, C.; Crean, J. K.; Brazil, D. P. Jagged/Notch signalling is required for a subset of TGFbeta1 responses in human kidney epithelial cells. Biochim. Biophys. Acta. 2010, 1803, 1386-1395.
-
(2010)
Biochim. Biophys. Acta.
, vol.1803
, pp. 1386-1395
-
-
Nyhan, K.C.1
Faherty, N.2
Murray, G.3
Cooey, L.B.4
Godson, C.5
Crean, J.K.6
Brazil, D.P.7
-
52
-
-
36549010842
-
Jagged1-mediated Notch activation induces epithelialto-mesenchymal transition through Slug-induced repression of Ecadherin
-
Leong, K. G.; Niessen, K.; Kulic, I.; Raouf, A.; Eaves, C.; Pollet, I.; Karsan, A. Jagged1-mediated Notch activation induces epithelialto-mesenchymal transition through Slug-induced repression of Ecadherin. J. Exp. Med. 2007, 204, 2935-2948.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2935-2948
-
-
Leong, K.G.1
Niessen, K.2
Kulic, I.3
Raouf, A.4
Eaves, C.5
Pollet, I.6
Karsan, A.7
-
53
-
-
75549083984
-
Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
-
Chen, J.; Imanaka, N.; Griffin, J. D. Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion. Br. J. Cancer 2010, 102, 351-360.
-
(2010)
Br. J. Cancer
, vol.102
, pp. 351-360
-
-
Chen, J.1
Imanaka, N.2
Griffin, J.D.3
-
54
-
-
84873702799
-
Mesenchymal stem cells regulate epithelialmesenchymal transition and tumor progression of pancreatic cancer cells
-
Kabashima-Niibe, A.; Higuchi, H.; Takaishi, H.; Masugi, Y.; Matsuzaki, Y.; Mabuchi, Y.; Funakoshi, S.; Adachi, M.; Hamamoto, Y.; Kawachi, S.; Aiura, K.; Kitagawa, Y.; Sakamoto, M.; Hibi, T. Mesenchymal stem cells regulate epithelialmesenchymal transition and tumor progression of pancreatic cancer cells. Cancer Sci. 2013, 104, 157-164.
-
(2013)
Cancer Sci.
, vol.104
, pp. 157-164
-
-
Kabashima-Niibe, A.1
Higuchi, H.2
Takaishi, H.3
Masugi, Y.4
Matsuzaki, Y.5
Mabuchi, Y.6
Funakoshi, S.7
Adachi, M.8
Hamamoto, Y.9
Kawachi, S.10
Aiura, K.11
Kitagawa, Y.12
Sakamoto, M.13
Hibi, T.14
-
55
-
-
84867056874
-
Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma
-
Tanaka, S.; Shiraha, H.; Nakanishi, Y.; Nishina, S.; Matsubara, M.; Horiguchi, S.; Takaoka, N.; Iwamuro, M.; Kataoka, J.; Kuwaki, K.; Hagihara, H.; Toshimori, J.; Ohnishi, H.; Takaki, A.; Nakamura, S.; Nouso, K.; Yagi, T.; Yamamoto, K. Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma. Int. J. Cancer 2012, 131, 2537-2546.
-
(2012)
Int. J. Cancer
, vol.131
, pp. 2537-2546
-
-
Tanaka, S.1
Shiraha, H.2
Nakanishi, Y.3
Nishina, S.4
Matsubara, M.5
Horiguchi, S.6
Takaoka, N.7
Iwamuro, M.8
Kataoka, J.9
Kuwaki, K.10
Hagihara, H.11
Toshimori, J.12
Ohnishi, H.13
Takaki, A.14
Nakamura, S.15
Nouso, K.16
Yagi, T.17
Yamamoto, K.18
-
56
-
-
79951813950
-
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
-
Brabletz, S.; Bajdak, K.; Meidhof, S.; Burk, U.; Niedermann, G.; Firat, E.; Wellner, U.; Dimmler, A.; Faller, G.; Schubert, J.; Brabletz, T. The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J. 2011, 30, 770-782.
-
(2011)
EMBO J.
, vol.30
, pp. 770-782
-
-
Brabletz, S.1
Bajdak, K.2
Meidhof, S.3
Burk, U.4
Niedermann, G.5
Firat, E.6
Wellner, U.7
Dimmler, A.8
Faller, G.9
Schubert, J.10
Brabletz, T.11
-
57
-
-
79953329774
-
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice
-
Yang, Y.; Ahn, Y. H.; Gibbons, D. L.; Zang Y.; Lin, W.; Thilaganathan, N.; Alvarez, C. A.; Moreira, D. C.; Creighton, C. J.; Gregory, P. A.; Goodall, G. J.; Kurie, J. M. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J. Clin. Invest. 2011, 121, 1373-1385.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1373-1385
-
-
Yang, Y.1
Ahn, Y.H.2
Gibbons, D.L.3
Zang, Y.4
Lin, W.5
Thilaganathan, N.6
Alvarez, C.A.7
Moreira, D.C.8
Creighton, C.J.9
Gregory, P.A.10
Goodall, G.J.11
Kurie, J.M.12
-
58
-
-
85027941540
-
Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells
-
Xing, F.; Okuda, H.; Watabe, M.; Kobayashi, A.; Pai, S. K.; Liu, W.; Pandey, P. R.; Fukuda; K.; Hirota, S.; Sugai, T.; Wakabayshi, G.; Koeda, K.; Kashiwaba, M.; Suzuki, K.; Chiba, T.; Endo, M.; Mo, Y. Y.; Watabe, K. Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells. Oncogene 2011, 30, 4075-4086.
-
(2011)
Oncogene
, vol.30
, pp. 4075-4086
-
-
Xing, F.1
Okuda, H.2
Watabe, M.3
Kobayashi, A.4
Pai, S.K.5
Liu, W.6
Pandey, P.R.7
Fukuda, K.8
Hirota, S.9
Sugai, T.10
Wakabayshi, G.11
Koeda, K.12
Kashiwaba, M.13
Suzuki, K.14
Chiba, T.15
Endo, M.16
Mo, Y.Y.17
Watabe, K.18
-
59
-
-
84880873734
-
Bone marrow-derived CD11b+Jagged-2+ cells promote epithelial to mesenchymal transition and metastization in colorectal cancer
-
Caiado, F.; Carvalho, T.; Rosa, I.; Remédio, L.; Costa, A.; Matos, J.; Heissig, B.; Yagita, H.; Hattori, K.; da Silva, J. P.; Fidalgo, P.; Pereira, A. D.; Dias, S. Bone marrow-derived CD11b+Jagged-2+ cells promote epithelial to mesenchymal transition and metastization in colorectal cancer. Cancer Res. 2013, 73(14), 4233-4246.
-
(2013)
Cancer Res.
, vol.73
, Issue.14
, pp. 4233-4246
-
-
Caiado, F.1
Carvalho, T.2
Rosa, I.3
Remédio, L.4
Costa, A.5
Matos, J.6
Heissig, B.7
Yagita, H.8
Hattori, K.9
da Silva, J.P.10
Fidalgo, P.11
Pereira, A.D.12
Dias, S.13
-
60
-
-
84879422834
-
Notch inhibitors for cancer treatment
-
Espinoza, I.; Miele, L. Notch inhibitors for cancer treatment. Pharmacol. Ther. 2013, 139(2), 95-110
-
(2013)
Pharmacol. Ther.
, vol.139
, Issue.2
, pp. 95-110
-
-
Espinoza, I.1
Miele, L.2
-
61
-
-
84867687369
-
Epithelial mesenchymal transition and pancreatic tumor initiating CD44+/EpCAM+ cells are inhibited by gamma-secretase inhibitor IX
-
Palagani, V.; El, Khatib. M.; Kossatz, U.; Bozko, P.; Müller, M. R.; Manns, M. P.; Krech, T.; Malek, N. P.; Plentz, R. R. Epithelial mesenchymal transition and pancreatic tumor initiating CD44+/EpCAM+ cells are inhibited by gamma-secretase inhibitor IX. PLoS One 2012, 7, e46514.
-
(2012)
PLoS One
, vol.7
-
-
Palagani, V.1
El Khatib, M.2
Kossatz, U.3
Bozko, P.4
Müller, M.R.5
Manns, M.P.6
Krech, T.7
Malek, N.P.8
Plentz, R.R.9
-
62
-
-
84859496041
-
Notch inhibition as a promising new approach to cancer therapy
-
Purow, B. Notch inhibition as a promising new approach to cancer therapy. Adv. Exp. Med. Biol. 2012, 727, 305-319.
-
(2012)
Adv. Exp. Med. Biol.
, vol.727
, pp. 305-319
-
-
Purow, B.1
-
63
-
-
33646877856
-
Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells
-
Wang, Z.; Zhang, Y.; Banerjee, S.; Li, Y.; Sarkar, F. H. Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells. Cancer 2006, 106, 2503-2513.
-
(2006)
Cancer
, vol.106
, pp. 2503-2513
-
-
Wang, Z.1
Zhang, Y.2
Banerjee, S.3
Li, Y.4
Sarkar, F.H.5
-
64
-
-
33645064160
-
Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells
-
Wang, Z.; Zhang, Y.; Banerjee, S.; Li, Y.; Sarkar, F. H. Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells. Int. J. Cancer 2006, 118, 1930-1936.
-
(2006)
Int. J. Cancer
, vol.118
, pp. 1930-1936
-
-
Wang, Z.1
Zhang, Y.2
Banerjee, S.3
Li, Y.4
Sarkar, F.H.5
-
65
-
-
69249096109
-
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
-
Li, Y.; VandenBoom, T. G. 2nd.; Kong, D.; Wang, Z.; Ali, S.; Philip, P. A.; Sarkar, F. H. Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res. 2009, 69, 6704-6712.
-
(2009)
Cancer Res.
, vol.69
, pp. 6704-6712
-
-
Li, Y.1
VandenBoom 2nd, T.G.2
Kong, D.3
Wang, Z.4
Ali, S.5
Philip, P.A.6
Sarkar, F.H.7
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