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Volumn 63, Issue 11, 2015, Pages 1997-2009

Slow degradation in phagocytic astrocytes can be enhanced by lysosomal acidification

Author keywords

Digestion; Glia; Lysosome; Nanoparticle; Nox2; Phagocytosis; PHrodo; Rab27a

Indexed keywords

ACTIN; ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NANOPARTICLE; RAB27A PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

EID: 84941192839     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22873     Document Type: Article
Times cited : (41)

References (68)
  • 1
    • 33646380409 scopus 로고    scopus 로고
    • The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides
    • Abramov AY, Duchen MR. 2005. The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides. Philos Trans R Soc Lond B: Biol Sci 360:2309-2314.
    • (2005) Philos Trans R Soc Lond B: Biol Sci , vol.360 , pp. 2309-2314
    • Abramov, A.Y.1    Duchen, M.R.2
  • 4
    • 0032524997 scopus 로고    scopus 로고
    • Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation
    • Aloisi F, Ria F, Penna G, Adorini L. 1998. Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation. J Immunol 160:4671-4680.
    • (1998) J Immunol , vol.160 , pp. 4671-4680
    • Aloisi, F.1    Ria, F.2    Penna, G.3    Adorini, L.4
  • 6
    • 84905868301 scopus 로고    scopus 로고
    • When astrocytes become harmful: Functional and inflammatory responses that contribute to Alzheimer's disease
    • Avila-Munoz E, Arias C. 2014. When astrocytes become harmful: Functional and inflammatory responses that contribute to Alzheimer's disease. Ageing Res Rev 18:29-40.
    • (2014) Ageing Res Rev , vol.18 , pp. 29-40
    • Avila-Munoz, E.1    Arias, C.2
  • 7
    • 84880713815 scopus 로고    scopus 로고
    • Measurement of phagocytic engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester
    • Unit 14 31.
    • Aziz M, Yang WL, Wang P. 2013. Measurement of phagocytic engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester. Curr Protoc Immunol Chapter 14:Unit 14 31.
    • (2013) Curr Protoc Immunol Chapter , vol.14
    • Aziz, M.1    Yang, W.L.2    Wang, P.3
  • 8
    • 84871336127 scopus 로고    scopus 로고
    • Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells
    • Baltazar GC, Guha S, Lu W, Lim J, Boesze-Battaglia K, Laties AM, Tyagi P, Kompella UB, Mitchell CH. 2012. Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells. PLoS One 7:e49635.
    • (2012) PLoS One , vol.7 , pp. e49635
    • Baltazar, G.C.1    Guha, S.2    Lu, W.3    Lim, J.4    Boesze-Battaglia, K.5    Laties, A.M.6    Tyagi, P.7    Kompella, U.B.8    Mitchell, C.H.9
  • 9
    • 1042278900 scopus 로고    scopus 로고
    • Class II MHC peptide loading by the professionals
    • Bryant P, Ploegh H. 2004. Class II MHC peptide loading by the professionals. Curr Opin Immunol 16:96-102.
    • (2004) Curr Opin Immunol , vol.16 , pp. 96-102
    • Bryant, P.1    Ploegh, H.2
  • 12
    • 0034231922 scopus 로고    scopus 로고
    • Phosphatidylserine-dependent phagocytosis of apoptotic glioma cells by normal human microglia, astrocytes, and glioma cells
    • Chang GH, Barbaro NM, Pieper RO. 2000. Phosphatidylserine-dependent phagocytosis of apoptotic glioma cells by normal human microglia, astrocytes, and glioma cells. Neuro Oncol 2:174-183.
    • (2000) Neuro Oncol , vol.2 , pp. 174-183
    • Chang, G.H.1    Barbaro, N.M.2    Pieper, R.O.3
  • 14
    • 84876668625 scopus 로고    scopus 로고
    • Emerging roles of astrocytes in neural circuit development
    • Clarke LE, Barres BA. 2013. Emerging roles of astrocytes in neural circuit development. Nat Rev Neurosci 14:311-321.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 311-321
    • Clarke, L.E.1    Barres, B.A.2
  • 15
    • 0032540248 scopus 로고    scopus 로고
    • Lysosomal enzyme trafficking between phagosomes, endosomes, and lysosomes in J774 macrophages. Enrichment of cathepsin H in early endosomes
    • Claus V, Jahraus A, Tjelle T, Berg T, Kirschke H, Faulstich H, Griffiths G. 1998. Lysosomal enzyme trafficking between phagosomes, endosomes, and lysosomes in J774 macrophages. Enrichment of cathepsin H in early endosomes. J Biol Chem 273:9842-9851.
    • (1998) J Biol Chem , vol.273 , pp. 9842-9851
    • Claus, V.1    Jahraus, A.2    Tjelle, T.3    Berg, T.4    Kirschke, H.5    Faulstich, H.6    Griffiths, G.7
  • 17
    • 3042527868 scopus 로고    scopus 로고
    • The NADPH oxidase of professional phagocytes-prototype of the NOX electron transport chain systems
    • Cross AR, Segal AW. 2004. The NADPH oxidase of professional phagocytes-prototype of the NOX electron transport chain systems. Biochim Biophys Acta 1657:1-22.
    • (2004) Biochim Biophys Acta , vol.1657 , pp. 1-22
    • Cross, A.R.1    Segal, A.W.2
  • 18
    • 0027941902 scopus 로고
    • A self-renewing multipotential stem cell in embryonic rat cerebral cortex
    • Davis AA, Temple S. 1994. A self-renewing multipotential stem cell in embryonic rat cerebral cortex. Nature 372:263-266.
    • (1994) Nature , vol.372 , pp. 263-266
    • Davis, A.A.1    Temple, S.2
  • 19
    • 14844340568 scopus 로고    scopus 로고
    • Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate
    • Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. 2005. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science 307:1630-1634.
    • (2005) Science , vol.307 , pp. 1630-1634
    • Delamarre, L.1    Pack, M.2    Chang, H.3    Mellman, I.4    Trombetta, E.S.5
  • 20
    • 84865531819 scopus 로고    scopus 로고
    • Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder
    • Di Malta C, Fryer JD, Settembre C, Ballabio A. 2012a. Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder. Proc Natl Acad Sci USA 109:E2334-E2342.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. E2334-E2342
    • Di Malta, C.1    Fryer, J.D.2    Settembre, C.3    Ballabio, A.4
  • 21
    • 84870924926 scopus 로고    scopus 로고
    • Autophagy in astrocytes: A novel culprit in lysosomal storage disorders. Autophagy
    • Di Malta C, Fryer JD, Settembre C, Ballabio A. 2012b. Autophagy in astrocytes: A novel culprit in lysosomal storage disorders. Autophagy 8:1871-1872.
    • (2012) , vol.8 , pp. 1871-1872
    • Di Malta, C.1    Fryer, J.D.2    Settembre, C.3    Ballabio, A.4
  • 22
    • 84896381325 scopus 로고    scopus 로고
    • A review of reagents for fluorescence microscopy of cellular compartments and structures, part I: BacMam labeling and reagents for vesicular structures
    • Unit 12 30
    • Dolman NJ, Kilgore JA, Davidson MW. 2013. A review of reagents for fluorescence microscopy of cellular compartments and structures, part I: BacMam labeling and reagents for vesicular structures. Curr Protoc Cytom Chapter 12:Unit 12 30.
    • (2013) Curr Protoc Cytom Chapter , vol.12
    • Dolman, N.J.1    Kilgore, J.A.2    Davidson, M.W.3
  • 23
    • 0035153212 scopus 로고    scopus 로고
    • Immune function of astrocytes
    • Dong Y, Benveniste EN. 2001. Immune function of astrocytes. Glia 36:180-190.
    • (2001) Glia , vol.36 , pp. 180-190
    • Dong, Y.1    Benveniste, E.N.2
  • 26
    • 10744227344 scopus 로고    scopus 로고
    • Astrocytes: A cellular player in Abeta clearance and degradation
    • Guenette SY. 2003. Astrocytes: A cellular player in Abeta clearance and degradation. Trends Mol Med 9:279-280.
    • (2003) Trends Mol Med , vol.9 , pp. 279-280
    • Guenette, S.Y.1
  • 27
    • 0036467586 scopus 로고    scopus 로고
    • Trafficking of MHC class II molecules in the late secretory pathway
    • Hiltbold EM, Roche PA. 2002. Trafficking of MHC class II molecules in the late secretory pathway. Curr Opin Immunol 14:30-35.
    • (2002) Curr Opin Immunol , vol.14 , pp. 30-35
    • Hiltbold, E.M.1    Roche, P.A.2
  • 31
    • 67650034374 scopus 로고    scopus 로고
    • Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes
    • Jensen MD, Sheng W, Simonyi A, Johnson GS, Sun AY, Sun GY. 2009. Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes. Neurochem Int 55:362-368.
    • (2009) Neurochem Int , vol.55 , pp. 362-368
    • Jensen, M.D.1    Sheng, W.2    Simonyi, A.3    Johnson, G.S.4    Sun, A.Y.5    Sun, G.Y.6
  • 32
    • 79961158069 scopus 로고    scopus 로고
    • Traumatic brain injury and amyloid-beta pathology: A link to Alzheimer's disease?
    • Johnson VE, Stewart W, Smith DH. 2010. Traumatic brain injury and amyloid-beta pathology: A link to Alzheimer's disease? Nat Rev Neurosci 11:361-370.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 361-370
    • Johnson, V.E.1    Stewart, W.2    Smith, D.H.3
  • 33
    • 84874650512 scopus 로고    scopus 로고
    • Amyloid-beta-induced astrocytic phagocytosis is mediated by CD36, CD47 and RAGE
    • Jones RS, Minogue AM, Connor TJ, Lynch MA. 2013. Amyloid-beta-induced astrocytic phagocytosis is mediated by CD36, CD47 and RAGE. J Neuroimmune Pharmacol 8:301-311.
    • (2013) J Neuroimmune Pharmacol , vol.8 , pp. 301-311
    • Jones, R.S.1    Minogue, A.M.2    Connor, T.J.3    Lynch, M.A.4
  • 34
    • 55849148388 scopus 로고    scopus 로고
    • Recruitment of Rab27a to phagosomes controls microbial antigen cross-presentation by dendritic cells
    • Kim SH, Visser A, Cruijsen C, van der Velden AW, Boes M. 2008. Recruitment of Rab27a to phagosomes controls microbial antigen cross-presentation by dendritic cells. Infect Immun 76:5373-5380.
    • (2008) Infect Immun , vol.76 , pp. 5373-5380
    • Kim, S.H.1    Visser, A.2    Cruijsen, C.3    van der Velden, A.W.4    Boes, M.5
  • 35
  • 36
    • 33748522053 scopus 로고    scopus 로고
    • Clearance of apoptotic and necrotic cells and its immunological consequences
    • Krysko DV, D'Herde K, Vandenabeele P. 2006. Clearance of apoptotic and necrotic cells and its immunological consequences. Apoptosis 11:1709-1726.
    • (2006) Apoptosis , vol.11 , pp. 1709-1726
    • Krysko, D.V.1    D'Herde, K.2    Vandenabeele, P.3
  • 37
    • 70350005334 scopus 로고    scopus 로고
    • Transient assembly of F-actin by phagosomes delays phagosome fusion with lysosomes in cargo-overloaded macrophages
    • Liebl D, Griffiths G. 2009. Transient assembly of F-actin by phagosomes delays phagosome fusion with lysosomes in cargo-overloaded macrophages. J Cell Sci 122:2935-2945.
    • (2009) J Cell Sci , vol.122 , pp. 2935-2945
    • Liebl, D.1    Griffiths, G.2
  • 38
    • 84858851237 scopus 로고    scopus 로고
    • Engulfing astrocytes protect neurons from contact-induced apoptosis following injury
    • Loov C, Hillered L, Ebendal T, Erlandsson A. 2012. Engulfing astrocytes protect neurons from contact-induced apoptosis following injury. PLoS One 7:e33090.
    • (2012) PLoS One , vol.7 , pp. e33090
    • Loov, C.1    Hillered, L.2    Ebendal, T.3    Erlandsson, A.4
  • 40
    • 46849094295 scopus 로고    scopus 로고
    • Moderate and severe traumatic brain injury in adults
    • Maas AI, Stocchetti N, Bullock R. 2008. Moderate and severe traumatic brain injury in adults. Lancet Neurol 7:728-741.
    • (2008) Lancet Neurol , vol.7 , pp. 728-741
    • Maas, A.I.1    Stocchetti, N.2    Bullock, R.3
  • 41
    • 0036715053 scopus 로고    scopus 로고
    • Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: Implications for the role of glial cells in the inflamed central nervous system
    • Magnus T, Chan A, Linker RA, Toyka KV, Gold R. 2002. Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: Implications for the role of glial cells in the inflamed central nervous system. J Neuropathol Exp Neurol 61:760-766.
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 760-766
    • Magnus, T.1    Chan, A.2    Linker, R.A.3    Toyka, K.V.4    Gold, R.5
  • 42
    • 77955912778 scopus 로고    scopus 로고
    • Traumatic brain injury: A disease process, not an event
    • Masel BE, DeWitt DS. 2010. Traumatic brain injury: A disease process, not an event. J Neurotrauma 27:1529-1540.
    • (2010) J Neurotrauma , vol.27 , pp. 1529-1540
    • Masel, B.E.1    DeWitt, D.S.2
  • 43
    • 59949083330 scopus 로고    scopus 로고
    • A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester
    • Miksa M, Komura H, Wu R, Shah KG, Wang P. 2009. A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester. J Immunol Methods 342:71-77.
    • (2009) J Immunol Methods , vol.342 , pp. 71-77
    • Miksa, M.1    Komura, H.2    Wu, R.3    Shah, K.G.4    Wang, P.5
  • 44
    • 0037427384 scopus 로고    scopus 로고
    • Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
    • Nagele RG, D'Andrea MR, Lee H, Venkataraman V, Wang HY. 2003. Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains. Brain Res 971:197-209.
    • (2003) Brain Res , vol.971 , pp. 197-209
    • Nagele, R.G.1    D'Andrea, M.R.2    Lee, H.3    Venkataraman, V.4    Wang, H.Y.5
  • 45
    • 0041926623 scopus 로고    scopus 로고
    • A new role for astrocytes: beta-amyloid homeostasis and degradation
    • Nicoll JA, Weller RO. 2003. A new role for astrocytes: beta-amyloid homeostasis and degradation. Trends Mol Med 9:281-282.
    • (2003) Trends Mol Med , vol.9 , pp. 281-282
    • Nicoll, J.A.1    Weller, R.O.2
  • 46
    • 77954375412 scopus 로고    scopus 로고
    • Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins
    • Nielsen HM, Mulder SD, Belien JA, Musters RJ, Eikelenboom P, Veerhuis R. 2010. Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins. Glia 58:1235-1246.
    • (2010) Glia , vol.58 , pp. 1235-1246
    • Nielsen, H.M.1    Mulder, S.D.2    Belien, J.A.3    Musters, R.J.4    Eikelenboom, P.5    Veerhuis, R.6
  • 47
    • 67650741983 scopus 로고    scopus 로고
    • Binding and uptake of A beta1-42 by primary human astrocytes in vitro
    • Nielsen HM, Veerhuis R, Holmqvist B, Janciauskiene S. 2009. Binding and uptake of A beta1-42 by primary human astrocytes in vitro. Glia 57:978-988.
    • (2009) Glia , vol.57 , pp. 978-988
    • Nielsen, H.M.1    Veerhuis, R.2    Holmqvist, B.3    Janciauskiene, S.4
  • 49
    • 48249103491 scopus 로고    scopus 로고
    • Neurodegenerative lysosomal disorders: A continuum from development to late age
    • Nixon RA, Yang DS, Lee JH. 2008. Neurodegenerative lysosomal disorders: A continuum from development to late age. Autophagy 4:590-599.
    • (2008) Autophagy , vol.4 , pp. 590-599
    • Nixon, R.A.1    Yang, D.S.2    Lee, J.H.3
  • 50
    • 84871960929 scopus 로고    scopus 로고
    • The cell biology of disease: Lysosomal storage disorders: The cellular impact of lysosomal dysfunction
    • Platt FM, Boland B, van der Spoel AC. 2012. The cell biology of disease: Lysosomal storage disorders: The cellular impact of lysosomal dysfunction. J Cell Biol 199:723-734.
    • (2012) J Cell Biol , vol.199 , pp. 723-734
    • Platt, F.M.1    Boland, B.2    van der Spoel, A.C.3
  • 51
    • 76749086068 scopus 로고    scopus 로고
    • Molecular mechanisms of late apoptotic/necrotic cell clearance
    • Poon IK, Hulett MD, Parish CR. 2010. Molecular mechanisms of late apoptotic/necrotic cell clearance. Cell Death Differ 17:381-397.
    • (2010) Cell Death Differ , vol.17 , pp. 381-397
    • Poon, I.K.1    Hulett, M.D.2    Parish, C.R.3
  • 53
    • 34548574975 scopus 로고    scopus 로고
    • Phagocytosis and antigen presentation in dendritic cells
    • Savina A, Amigorena S. 2007. Phagocytosis and antigen presentation in dendritic cells. Immunol Rev 219:143-156.
    • (2007) Immunol Rev , vol.219 , pp. 143-156
    • Savina, A.1    Amigorena, S.2
  • 55
    • 64449088219 scopus 로고    scopus 로고
    • The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells
    • Savina A, Peres A, Cebrian I, Carmo N, Moita C, Hacohen N, Moita LF, Amigorena S. 2009. The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells. Immunity 30:544-555.
    • (2009) Immunity , vol.30 , pp. 544-555
    • Savina, A.1    Peres, A.2    Cebrian, I.3    Carmo, N.4    Moita, C.5    Hacohen, N.6    Moita, L.F.7    Amigorena, S.8
  • 56
    • 0036137684 scopus 로고    scopus 로고
    • Rab GTPases, intracellular traffic and disease
    • Seabra MC, Mules EH, Hume AN. 2002. Rab GTPases, intracellular traffic and disease. Trends Mol Med 8:23-30.
    • (2002) Trends Mol Med , vol.8 , pp. 23-30
    • Seabra, M.C.1    Mules, E.H.2    Hume, A.N.3
  • 58
    • 84867358425 scopus 로고    scopus 로고
    • Dementia resulting from traumatic brain injury: what is the pathology?
    • Shively S, Scher AI, Perl DP, Diaz-Arrastia R. 2012. Dementia resulting from traumatic brain injury: what is the pathology? Arch Neurol 69:1245-1251.
    • (2012) Arch Neurol , vol.69 , pp. 1245-1251
    • Shively, S.1    Scher, A.I.2    Perl, D.P.3    Diaz-Arrastia, R.4
  • 59
    • 70449678738 scopus 로고    scopus 로고
    • Molecular dissection of reactive astrogliosis and glial scar formation
    • Sofroniew MV. 2009. Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci 32:638-647.
    • (2009) Trends Neurosci , vol.32 , pp. 638-647
    • Sofroniew, M.V.1
  • 61
    • 79957912374 scopus 로고    scopus 로고
    • Brain-specific angiogenesis inhibitor-1 expression in astrocytes and neurons: Implications for its dual function as an apoptotic engulfment receptor
    • Sokolowski JD, Nobles SL, Heffron DS, Park D, Ravichandran KS, Mandell JW. 2011. Brain-specific angiogenesis inhibitor-1 expression in astrocytes and neurons: Implications for its dual function as an apoptotic engulfment receptor. Brain Behav Immun 25:915-921.
    • (2011) Brain Behav Immun , vol.25 , pp. 915-921
    • Sokolowski, J.D.1    Nobles, S.L.2    Heffron, D.S.3    Park, D.4    Ravichandran, K.S.5    Mandell, J.W.6
  • 62
    • 0032775459 scopus 로고    scopus 로고
    • Differential expression of B7 co-stimulatory molecules by astrocytes correlates with T cell activation and cytokine production
    • Soos JM, Ashley TA, Morrow J, Patarroyo JC, Szente BE, Zamvil SS. 1999. Differential expression of B7 co-stimulatory molecules by astrocytes correlates with T cell activation and cytokine production. Int Immunol 11:1169-1179.
    • (1999) Int Immunol , vol.11 , pp. 1169-1179
    • Soos, J.M.1    Ashley, T.A.2    Morrow, J.3    Patarroyo, J.C.4    Szente, B.E.5    Zamvil, S.S.6
  • 63
    • 84989741895 scopus 로고
    • Excited state pKa behaviour of DAPI. A rationalization of the fluorescence enhancement of DAPI in DAPI-nucleic acid complexes
    • Szabo AG, Krajcarski DT, Cavatorta P, Masotti L, Barcellona ML. 1986. Excited state pKa behaviour of DAPI. A rationalization of the fluorescence enhancement of DAPI in DAPI-nucleic acid complexes. Photochem Photobiol 44:143-150.
    • (1986) Photochem Photobiol , vol.44 , pp. 143-150
    • Szabo, A.G.1    Krajcarski, D.T.2    Cavatorta, P.3    Masotti, L.4    Barcellona, M.L.5
  • 66
    • 0037308678 scopus 로고    scopus 로고
    • Reactive astrocytes in chronic active lesions of multiple sclerosis express co-stimulatory molecules B7-1 and B7-2
    • Zeinstra E, Wilczak N, De Keyser J. 2003. Reactive astrocytes in chronic active lesions of multiple sclerosis express co-stimulatory molecules B7-1 and B7-2. J Neuroimmunol 135:166-171.
    • (2003) J Neuroimmunol , vol.135 , pp. 166-171
    • Zeinstra, E.1    Wilczak, N.2    De Keyser, J.3
  • 67
    • 52949150791 scopus 로고    scopus 로고
    • Phagosome maturation during the removal of apoptotic cells: Receptors lead the way
    • Zhou Z, Yu X. 2008. Phagosome maturation during the removal of apoptotic cells: Receptors lead the way. Trends Cell Biol 18:474-485.
    • (2008) Trends Cell Biol , vol.18 , pp. 474-485
    • Zhou, Z.1    Yu, X.2
  • 68
    • 67650888887 scopus 로고    scopus 로고
    • NAD(P)H oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A2
    • Zhu D, Hu C, Sheng W, Tan KS, Haidekker MA, Sun AY, Sun GY, Lee JC. 2009. NAD(P)H oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A2. Biochem J 421:201-210.
    • (2009) Biochem J , vol.421 , pp. 201-210
    • Zhu, D.1    Hu, C.2    Sheng, W.3    Tan, K.S.4    Haidekker, M.A.5    Sun, A.Y.6    Sun, G.Y.7    Lee, J.C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.