메뉴 건너뛰기




Volumn 39, Issue 9, 2015, Pages 1632-1641

The Role of miR-212 and iNOS in Alcohol-Induced Intestinal Barrier Dysfunction and Steatohepatitis

Author keywords

Alcoholic Liver Disease; Inducible Nitric Oxide Synthase; Intestinal Permeability; MicroRNA 212; Zonula Occludens 1

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; MICRORNA; MICRORNA 122; MICRORNA 212; PROTEIN ZO1; UNCLASSIFIED DRUG; ALCOHOL; MIRN122 MICRORNA, MOUSE; NOS2 PROTEIN, MOUSE;

EID: 84941168421     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12813     Document Type: Article
Times cited : (60)

References (52)
  • 1
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V (2004) The functions of animal microRNAs. Nature 431:350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 2
    • 0033838638 scopus 로고    scopus 로고
    • Nitric oxide and its metabolites mediate ethanol-induced microtubule disruption and intestinal barrier dysfunction
    • Banan A, Fields JZ, Decker H, Zhang Y, Keshavarzian A (2000a) Nitric oxide and its metabolites mediate ethanol-induced microtubule disruption and intestinal barrier dysfunction. J Pharmacol Exp Ther 294:997-1008.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 997-1008
    • Banan, A.1    Fields, J.Z.2    Decker, H.3    Zhang, Y.4    Keshavarzian, A.5
  • 3
    • 35048812999 scopus 로고    scopus 로고
    • NF-kappaB activation as a key mechanism in ethanol-induced disruption of the F-actin cytoskeleton and monolayer barrier integrity in intestinal epithelium
    • Banan A, Keshavarzian A, Zhang L, Shaikh M, Forsyth CB, Tang Y, Fields JZ (2007) NF-kappaB activation as a key mechanism in ethanol-induced disruption of the F-actin cytoskeleton and monolayer barrier integrity in intestinal epithelium. Alcohol 41:447-460.
    • (2007) Alcohol , vol.41 , pp. 447-460
    • Banan, A.1    Keshavarzian, A.2    Zhang, L.3    Shaikh, M.4    Forsyth, C.B.5    Tang, Y.6    Fields, J.Z.7
  • 4
    • 0034069867 scopus 로고    scopus 로고
    • Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor alpha in a human colonic cell line
    • Banan A, Zhang Y, Losurdo J, Keshavarzian A (2000b) Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor alpha in a human colonic cell line. Gut 46:830-837.
    • (2000) Gut , vol.46 , pp. 830-837
    • Banan, A.1    Zhang, Y.2    Losurdo, J.3    Keshavarzian, A.4
  • 5
    • 34247631655 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase from bone marrow-derived cells plays a critical role in regulating colonic inflammation
    • Beck PL, Li Y, Wong J, Chen CW, Keenan CM, Sharkey KA, McCafferty DM (2007) Inducible nitric oxide synthase from bone marrow-derived cells plays a critical role in regulating colonic inflammation. Gastroenterology 132:1778-1790.
    • (2007) Gastroenterology , vol.132 , pp. 1778-1790
    • Beck, P.L.1    Li, Y.2    Wong, J.3    Chen, C.W.4    Keenan, C.M.5    Sharkey, K.A.6    McCafferty, D.M.7
  • 6
    • 32044469602 scopus 로고    scopus 로고
    • Activation of the innate immune system and alcoholic liver disease: effects of ethanol per se or enhanced intestinal translocation of bacterial toxins induced by ethanol?
    • Bode C, Bode JC (2005) Activation of the innate immune system and alcoholic liver disease: effects of ethanol per se or enhanced intestinal translocation of bacterial toxins induced by ethanol? Alcohol Clin Exp Res 29(11 Suppl):166S-171S.
    • (2005) Alcohol Clin Exp Res , vol.29 , Issue.11 , pp. 166S-171S
    • Bode, C.1    Bode, J.C.2
  • 7
    • 78649433367 scopus 로고    scopus 로고
    • Histopathology of nonalcoholic fatty liver disease
    • Brunt EM, Tiniakos DG (2010) Histopathology of nonalcoholic fatty liver disease. World J Gastroenterol 16:5286-5296.
    • (2010) World J Gastroenterol , vol.16 , pp. 5286-5296
    • Brunt, E.M.1    Tiniakos, D.G.2
  • 9
    • 33644857025 scopus 로고    scopus 로고
    • Gene regulation by microRNAs
    • Carthew RW (2006) Gene regulation by microRNAs. Curr Opin Genet Dev 16:203-208.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 203-208
    • Carthew, R.W.1
  • 10
    • 2142813761 scopus 로고    scopus 로고
    • A porous defense: the leaky epithelial barrier in intestinal disease
    • Clayburgh DR, Shen L, Turner JR (2004) A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest 84:282-291.
    • (2004) Lab Invest , vol.84 , pp. 282-291
    • Clayburgh, D.R.1    Shen, L.2    Turner, J.R.3
  • 11
    • 33644982043 scopus 로고    scopus 로고
    • MicroRNAs as therapeutic targets
    • Czech MP (2006) MicroRNAs as therapeutic targets. N Engl J Med 354:1194-1195.
    • (2006) N Engl J Med , vol.354 , pp. 1194-1195
    • Czech, M.P.1
  • 12
    • 34249274957 scopus 로고    scopus 로고
    • Ethanol metabolism and effects: nitric oxide and its interaction
    • Deng XS, Deitrich RA (2007) Ethanol metabolism and effects: nitric oxide and its interaction. Curr Clin Pharmacol 2:145-153.
    • (2007) Curr Clin Pharmacol , vol.2 , pp. 145-153
    • Deng, X.S.1    Deitrich, R.A.2
  • 15
    • 61349161828 scopus 로고    scopus 로고
    • Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis
    • Forsyth CB, Farhadi A, Jakate SM, Tang Y, Shaikh M, Keshavarzian A (2009) Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis. Alcohol 43:163-172.
    • (2009) Alcohol , vol.43 , pp. 163-172
    • Forsyth, C.B.1    Farhadi, A.2    Jakate, S.M.3    Tang, Y.4    Shaikh, M.5    Keshavarzian, A.6
  • 16
    • 80052024454 scopus 로고    scopus 로고
    • Role of snail activation in alcohol-induced iNOS-mediated disruption of intestinal epithelial cell permeability
    • Forsyth CB, Tang Y, Shaikh M, Zhang L, Keshavarzian A (2011) Role of snail activation in alcohol-induced iNOS-mediated disruption of intestinal epithelial cell permeability. Alcohol Clin Exp Res 35:1635-1643.
    • (2011) Alcohol Clin Exp Res , vol.35 , pp. 1635-1643
    • Forsyth, C.B.1    Tang, Y.2    Shaikh, M.3    Zhang, L.4    Keshavarzian, A.5
  • 17
    • 0015461834 scopus 로고
    • Alcoholic hepatitis: its therapy and prognosis
    • Galambos J (1973) Alcoholic hepatitis: its therapy and prognosis. Prog Liver Dis 4:567-588.
    • (1973) Prog Liver Dis , vol.4 , pp. 567-588
    • Galambos, J.1
  • 19
    • 0026630075 scopus 로고
    • The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease
    • Hollander D (1992) The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease. Scand J Gastroenterol 27:721-726.
    • (1992) Scand J Gastroenterol , vol.27 , pp. 721-726
    • Hollander, D.1
  • 23
    • 59549106331 scopus 로고    scopus 로고
    • Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats
    • Keshavarzian A, Farhadi A, Forsyth CB, Rangan J, Jakate S, Shaikh M, Banan A, Fields JZ (2009) Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats. J Hepatol 50:538-547.
    • (2009) J Hepatol , vol.50 , pp. 538-547
    • Keshavarzian, A.1    Farhadi, A.2    Forsyth, C.B.3    Rangan, J.4    Jakate, S.5    Shaikh, M.6    Banan, A.7    Fields, J.Z.8
  • 24
    • 0344392928 scopus 로고    scopus 로고
    • Alcoholic liver disease: is it an "extraintestinal" complication of alcohol-induced intestinal injury?
    • Keshavarzian A, Fields J (2003) Alcoholic liver disease: is it an "extraintestinal" complication of alcohol-induced intestinal injury? J Lab Clin Med 142:285-287.
    • (2003) J Lab Clin Med , vol.142 , pp. 285-287
    • Keshavarzian, A.1    Fields, J.2
  • 32
    • 84881257067 scopus 로고    scopus 로고
    • Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice
    • Lippai D, Bala S, Csak T, Kurt-Jones EA, Szabo G (2013) Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice. PLoS ONE 8:e70945.
    • (2013) PLoS ONE , vol.8 , pp. e70945
    • Lippai, D.1    Bala, S.2    Csak, T.3    Kurt-Jones, E.A.4    Szabo, G.5
  • 33
    • 0025579702 scopus 로고
    • Warner-Lambert/Parke-Davis Award lecture. Pathobiology of the intestinal epithelial barrier
    • Madara JL (1990) Warner-Lambert/Parke-Davis Award lecture. Pathobiology of the intestinal epithelial barrier. Am J Pathol 137:1273-1281.
    • (1990) Am J Pathol , vol.137 , pp. 1273-1281
    • Madara, J.L.1
  • 34
    • 0036203509 scopus 로고    scopus 로고
    • Alcoholic steatosis and steatohepatitis
    • Maher JJ (2002a) Alcoholic steatosis and steatohepatitis. Semin Gastrointest Dis 13:31-39.
    • (2002) Semin Gastrointest Dis , vol.13 , pp. 31-39
    • Maher, J.J.1
  • 35
    • 0036097132 scopus 로고    scopus 로고
    • Treatment of alcoholic hepatitis
    • Maher JJ (2002b) Treatment of alcoholic hepatitis. J Gastroenterol Hepatol 17:448-455.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 448-455
    • Maher, J.J.1
  • 36
    • 84900821567 scopus 로고    scopus 로고
    • Animal models of alcohol-induced liver disease: pathophysiology, translational relevance and challenges
    • Mathews S, Xu M, Wang H, Bertola A, Gao B (2014) Animal models of alcohol-induced liver disease: pathophysiology, translational relevance and challenges. Am J Physiol Gastrointest Liver Physiol 306:G819-G823.
    • (2014) Am J Physiol Gastrointest Liver Physiol , vol.306 , pp. G819-G823
    • Mathews, S.1    Xu, M.2    Wang, H.3    Bertola, A.4    Gao, B.5
  • 39
    • 84897472831 scopus 로고    scopus 로고
    • Long-term effects of peripubertal binge EtOH exposure on hippocampal microRNA expression in the rat
    • Prins SA, Przybycien-Szymanska MM, Rao YS, Pak TR (2014) Long-term effects of peripubertal binge EtOH exposure on hippocampal microRNA expression in the rat. PLoS ONE 9:e83166.
    • (2014) PLoS ONE , vol.9 , pp. e83166
    • Prins, S.A.1    Przybycien-Szymanska, M.M.2    Rao, Y.S.3    Pak, T.R.4
  • 40
    • 33745248430 scopus 로고    scopus 로고
    • microRNA target predictions in animals
    • Rajewsky N (2006) microRNA target predictions in animals. Nat Genet 38(Suppl):S8-S13.
    • (2006) Nat Genet , vol.38 , pp. S8-S13
    • Rajewsky, N.1
  • 42
    • 84881519120 scopus 로고    scopus 로고
    • Epigenetic effects of ethanol on the liver and gastrointestinal system
    • Shukla SD, Lim RW (2013) Epigenetic effects of ethanol on the liver and gastrointestinal system. Alcohol Res 35:47-55.
    • (2013) Alcohol Res , vol.35 , pp. 47-55
    • Shukla, S.D.1    Lim, R.W.2
  • 43
    • 84884686952 scopus 로고    scopus 로고
    • Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian target of rapamycin signaling in regulating miR-132/-212 and miR-122/-181a expression in primary cultured rat hepatocytes
    • Shukla U, Tumma N, Gratsch T, Dombkowski A, Novak RF (2013) Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian target of rapamycin signaling in regulating miR-132/-212 and miR-122/-181a expression in primary cultured rat hepatocytes. Drug Metab Dispos 41:1769-1777.
    • (2013) Drug Metab Dispos , vol.41 , pp. 1769-1777
    • Shukla, U.1    Tumma, N.2    Gratsch, T.3    Dombkowski, A.4    Novak, R.F.5
  • 46
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 103:12481-12486.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 47
    • 38349109046 scopus 로고    scopus 로고
    • Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease
    • Tang Y, Banan A, Forsyth CB, Fields JZ, Lau CK, Zhang LJ, Keshavarzian A (2008) Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease. Alcohol Clin Exp Res 32:355-364.
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 355-364
    • Tang, Y.1    Banan, A.2    Forsyth, C.B.3    Fields, J.Z.4    Lau, C.K.5    Zhang, L.J.6    Keshavarzian, A.7
  • 48
    • 66749115646 scopus 로고    scopus 로고
    • Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damage
    • Tang Y, Forsyth CB, Banan A, Fields JZ, Keshavarzian A (2009a) Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damage. J Pharmacol Exp Ther 329:952-958.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 952-958
    • Tang, Y.1    Forsyth, C.B.2    Banan, A.3    Fields, J.Z.4    Keshavarzian, A.5
  • 50
    • 79955010455 scopus 로고    scopus 로고
    • MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection
    • Torres AG, Fabani MM, Vigorito E, Gait MJ (2011) MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection. RNA 17:933-943.
    • (2011) RNA , vol.17 , pp. 933-943
    • Torres, A.G.1    Fabani, M.M.2    Vigorito, E.3    Gait, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.