NH4+ triggers the release of astrocytic lactate via mitochondrial pyruvate shunting

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 35, 2015, Pages 11090-11095

  Lerchundi, Rodrigo ^a,b   Fernández Moncada, Ignacio ^a,b   Contreras Baeza, Yasna ^a,b   Sotelo Hitschfeld, Tamara ^a,b   Mächler, Philipp ^c   Wyss, Matthias T ^c   Stobart, Jillian ^c   Baeza Lehnert, Felipe ^a   Alegría, Karin ^a   Weber, Bruno ^c   Barros, L Felipe ^a  

^a CENTRO DE ESTUDIOS CIENTÍFICOS CECS   (Chile)

^b UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

FLII12Pglu700 6; Laconic; MitoSypHer; Peredox; Pyronic

Indexed keywords

AMMONIA; LACTIC ACID; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; AMMONIUM DERIVATIVE;

ACIDIFICATION; AEROBIC CAPACITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BIOACCUMULATION; BRAIN CELL CULTURE; CONTROLLED STUDY; CYTOSOL; EXTRACELLULAR SPACE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLUCOSE INTAKE; GLYCOLYSIS; HIPPOCAMPAL SLICE; INTRACELLULAR SIGNALING; MALE; MITOCHONDRION; MOUSE; NEUROTRANSMISSION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SOMATOSENSORY CORTEX; ANIMAL; METABOLISM;

AMMONIUM COMPOUNDS; ANIMALS; ASTROCYTES; LACTIC ACID; MICE; MITOCHONDRIA; PYRUVIC ACID;

EID: 84941003471     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1508259112     Document Type: Article

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