Na+-Ca2+ cosignaling in the stimulation of the glucose transporter GLUT1 in cultured astrocytes

GLIA

Volumn 56, Issue 1, 2008, Pages 59-68

  Porras, Omar H ^a   Ruminot, Ivan ^a,b   Loaiza, Anitsi ^a,b   Barros, Luis F ^a  

^a CENTRO DE ESTUDIOS CIENTÍFICOS CECS   (Chile)

^b UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

Author keywords

6 NBDG; D aspartate; Glucose; Glutamate; Membrane transport; TBOA

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; COTRANSPORTER; DEXTRO ASPARTIC ACID; ENDOTHELIN 1; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLUCOSE; GLUCOSE TRANSPORTER 1; GLUTAMATE SODIUM; GRAMICIDIN; OUABAIN; SODIUM; THREO BETA BENZYLOXYASPARTATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CONTROLLED STUDY; GLUCOSE TRANSPORT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; BRAIN; CALCIUM SIGNALING; CELL SIZE; CELLS, CULTURED; FLUORESCENT DYES; GLUCOSE TRANSPORTER TYPE 1; METHOXYHYDROXYPHENYLGLYCOL; MICROSCOPY, CONFOCAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, METABOTROPIC GLUTAMATE; SIGNAL TRANSDUCTION; SODIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE; TEMPERATURE;

EID: 36448983548     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20589     Document Type: Article

References (45)

1. Attwell D, Laughlin SB. 2001. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab 21:1133-1145.
2. Barnes K, Ingram JC, Porras OH, Barros LF, Hudson ER, Fryer LG, Foufelle F, Carling D, Hardie DG, Baldwin SA. 2002. Activation of GLUT1 by metabolic and osmotic stress: Potential involvement of AMP-activated protein kinase (AMPK). J Cell Sci 115:2433-2442.
3. Barros LF, Bittner CX, Loaiza A, Porras OH. 2007. A quantitative overview of glucose dynamics in the gliovascular unit. Glia 55:1222-1237.
4. Barros LF, Porras OH, Bittner CX. 2005. Why glucose transport in the brain matters for PET. Trends Neurosci 28:117-119.
5. +-mediated metabolic waves. Proc Natl Acad Sci USA 101:14937-14942.
6. 2+ signaling. Am J Physiol 277:C616-C627.
7. Bonvento G, Herard AS, Voutsinos-Porche B. 2005. The astrocyte-neuron lactate shuttle: A debated but still valuable hypothesis for brain imaging. J Cereb Blood Flow Metab 25:1394-1399.
8. + dynamics in mouse cortical astrocytes: Implications for cellular bioenergetics. Eur J Neurosci 12:3843-3853.
9. Chatton JY, Pellerin L, Magistretti PJ. 2003. GABA uptake into astrocytes is not associated with significant metabolic cost: Implications for brain imaging of inhibitory transmission. Proc Natl Acad Sci USA 100:12456-12461.
10. Dienel GA, Cruz NF. 2004. Nutrition during brain activation: Does cell-to-cell lactate shuttling contribute significantly to sweet and sour food for thought? Neurochem Int 45:321-351.
11. Draznin B, Sussman K, Kao M, Lewis D, Sherman N. 1987. The existence of an optimal range of cytosolic free calcium for insulin-stimulated glucose transport in rat adipocytes. J Biol Chem 262:14385-14388.
12. Fiacco TA, McCarthy KD. 2006. Astrocyte calcium elevations: properties, propagation, and effects on brain signaling. Glia 54:676-690.
13. Giaume C, Tabernero A, Medina JM. 1997. Metabolic trafficking through astrocytic gap junctions. Glia 21:114-123.
14. Gladden LB. 2004. Lactate metabolism: A new paradigm for the third millennium. J Physiol 558:5-30.
15. Gong XQ, Frandsen A, Lu WY, Wan Y, Zabek RL, Pickering DS, Bai D. 2005. D-aspartate and NMDA, but not L-aspartate, block AMPA receptors in rat hippocampal neurons. Br J Pharmacol 145:449-459.
16. Hertz L, Peng L, Dienel GA. 2007. Energy metabolism in astrocytes: High rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis. J Cereb Blood Flow Metab 27:219-249.
17. Huang YH, Muralidharan S, Sinha SR, Kao JP, Bergles DE. 2005. Ncm-D-aspartate: A novel caged D-aspartate suitable for activation of glutamate transporters and N-methyl-D-aspartate (NMDA) receptors in brain tissue. Neuropharmacology 49:831-842.
18. Hyder F, Chase JR, Behar KL, Mason GF, Siddeek M, Rothman DL, Shulman RG. 1996. Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR. Proc Natl Acad Sci USA 93:7612-7617.
19. Hyder F, Patel AB, Gjedde A, Rothman DL, Behar KL, Shulman RG. 2006. Neuronal-glial glucose oxidation and glutamatergic-GABAergic function. J Cereb Blood Flow Metab 26:865-877.
20. Kacem K, Lacombe P, Seylaz J, Bonvento G. 1998. Structural organization of the perivascular astrocyte endfeet and their relationship with the endothelial glucose transporter: A confocal microscopy study. Glia 23:1-10.
21. 2+ signaling in Bergmann glial cells in situ. Faseb J 11:566-572.
22. Kirischuk S, Kettenmann H, Verkhratsky A. 2007. Membrane currents and cytoplasmic sodium transients generated by glutamate transport in Bergmann glial cells. Plugers Arch Eur J Physiol 454:245-252.
23. Lalo U, Pankratov Y, Kirchhoff F, North RA, Verkhratsky A. 2006. NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J Neurosci 26:2673-2683.
24. Loaiza A, Porras OH, Barros LF. 2003. Glutamate triggers rapid glucose transport stimulation in astrocytes as evidenced by real-time confocal microscopy. J Neurosci 23:7337-7342.
25. Lowry JP, O'Neill RD, Boutelle MG, Fillenz M. 1998. Continuous monitoring of extracellular glucose concentrations in the striatum of freely moving rats with an implanted glucose biosensor. J Neurochem 70:391-396.
26. Maraldi T, Rugolo M, Fiorentini D, Landi L, Hakim G. 2006. Glucose transport activation in human hematopoietic cells M07e is modulated by cytosolic calcium and calmodulin. Cell Calcium 40:373-381.
27. Matthias K, Kirchhoff F, Seifert G, Huttmann K, Matyash M, Kettenmann H, Steinhauser C. 2003. Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J Neurosci 23: 1750-1758.
28. 2+ exchanger protein isoforms, NCX1, NCX2 and NCX3 in cerebral cortex and hippocampus of adult rat. Cell Calcium 41:221-234.
29. Pankratov YV, Krishtal OA. 2003. Distinct quantal features of AMPA and NMDA synaptic currents in hippocampal neurons: Implication of glutamate spillover and receptor saturation. Biophys J 85:3375-3387.
30. Pellerin L, Magistretti PJ. 1994. Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization. Proc Natl Acad Sci USA 91:10625-10629.
31. +-ATPase activity in astrocytes via activation of a distinct subunit highly sensitive to ouabain. J Neurochem 69:2132-2137.
32. Pellerin L, Magistretti PJ. 2004. Neuroenergetics: Calling upon astrocytes to satisfy hungry neurons. Neuroscientist 10:53-62.
33. Pellerin L, Magistretti PJ. 2005. Ampakine CX546 bolsters energetic response of astrocytes: A novel target for cognitive-enhancing drugs acting as α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor modulators. J Neurochem 92:668-677.
34. Porras OH, Loaiza A, Barros LF. 2004. Glutamate mediates acute glucose transport inhibition in hippocampal neurons. J Neurosci 24: 9669-9673.
35. Quintanilla RA, Porras OH, Castro J, Barros LF. 2000. Cytosolic [Ca(2+)] modulates basal GLUT1 activity and plays a permissive role in its activation by metabolic stress and insulin in rat epithelial cells. Cell Calcium 28:97-106.
36. Raichle ME, Mintun MA. 2006. Brain work and brain imaging. Annu Rev Neurosci 29:449-476.
37. Reddy VP, Obrenovich ME, Atwood CS, Perry G, Smith MA. 2002. Involvement of Maillard reactions in Alzheimer disease. Neurotox Res 4:191-209.
38. Rusakov DA, Kullmann DM. 1998. Extrasynaptic glutamate diffusion in the hippocampus: Ultrastructural constraints, uptake, and receptor activation. J Neurosci 18:3158-3170.
39. Scemes E, Giaume C. 2006. Astrocyte calcium waves: What they are and what they do. Glia 54:716-725.
40. Sen AK, Widdas W. 1962. Determination of the temperature and pH dependence of glucose transfer across the human erythrocyte membrane measured by glucose exit. J Physiol (Lond) 160:392-403.
41. Thomsen K, Offenhauser N, Lauritzen M. 2004. Principal neuron spiking: Neither necessary nor sufficient for cerebral blood flow in rat cerebellum. J Physiol 560:181-189.
42. Vannucci SJ, Maher F, Simpson IA. 1997. Glucose transporter proteins in brain: Delivery of glucose to neurons and glia. Glia 21:2-21.
43. Verkhratsky A. 2006. Glial calcium signaling in physiology and pathophysiology. Acta Pharmacol Sin 27:773-780.
44. Voutsinos-Porche B, Bonvento G, Tanaka K, Steiner P, Welker E, Chatton JY, Magistretti PJ, Pellerin L. 2003. Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex. Neuron 37:275-286.
45. 2+ signaling evoked by sensory stimulation in vivo. Nat Neurosci 9:816-823.