Exploring the molecular interactions of 7,8-dihydroxyflavone and its derivatives with TrkB and VEGFR2 proteins

International Journal of Molecular Sciences

Volumn 16, Issue 9, 2015, Pages 21087-21108

  Chitranshi, Nitin ^a   Gupta, Vivek ^a   Kumar, Sanjay ^b   Graham, Stuart L ^a,c  

^a MACQUARIE UNIVERSITY   (Australia)

^b Bioinformatics Centre   (India)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

7,8 DHF; BDNF; Docking; Glaucoma; Molecular dynamics; Neurodegenerative disorder; Retina; TrkB receptor; VEGFR2 receptor

Indexed keywords

7, 8 DIHYDROXYFLAVONE; 7, 8 DIHYDROXYFLAVONE DERIVATIVE; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; 6,7-DIHYDROXYFLAVONE; FLAVONE DERIVATIVE; PROTEIN BINDING;

ALGORITHM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; COMPUTER MODEL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EYE DISEASE; IMMUNOPRECIPITATION; MALE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PHOTORECEPTOR CELL; RAT; RETINA; WESTERN BLOTTING; ANIMAL; BINDING SITE; CHEMISTRY; DRUG EFFECTS; METABOLISM; MOLECULAR MODEL; PHOSPHORYLATION; RETINA CONE; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; BINDING SITES; FLAVONES; MALE; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; PHOSPHORYLATION; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; RETINA; RETINAL CONE PHOTORECEPTOR CELLS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84940979845     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160921087     Document Type: Article

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