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Volumn 18, Issue 2, 1999, Pages 363-374

A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

Author keywords

Angiogenesis; Flt 1; KDR; Orf virus; VEGF

Indexed keywords

CYSTEINE; PROTEIN TYROSINE KINASE; RECOMBINANT PROTEIN; THROMBOPLASTIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 0033556287     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.2.363     Document Type: Article
Times cited : (419)

References (64)
  • 1
    • 0031905861 scopus 로고    scopus 로고
    • Vascular cndothclial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
    • Achen, M.G., Jeltsch, M., Kukk, E., Makinen, T., Vitali, A., Wilks, A.F., Alitalo, K. and Stacker, S.A. (1998) Vascular cndothclial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc. Natl Acad Sci. USA, 95, 548-553.
    • (1998) Proc. Natl Acad Sci. USA , vol.95 , pp. 548-553
    • Achen, M.G.1    Jeltsch, M.2    Kukk, E.3    Makinen, T.4    Vitali, A.5    Wilks, A.F.6    Alitalo, K.7    Stacker, S.A.8
  • 3
    • 16144363412 scopus 로고    scopus 로고
    • The angiogenesis induced by HIV-1 Tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells
    • Adriana, A. et al. (1996b) The angiogenesis induced by HIV-1 Tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells. Nature Med., 2, 1371-1375.
    • (1996) Nature Med. , vol.2 , pp. 1371-1375
    • Adriana, A.1
  • 4
    • 0032583951 scopus 로고    scopus 로고
    • Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia
    • Baumgartner, I., Pieczek, A., Manor, O., Blair, R., Kearney, M., Walsh, K. and Isner, J.M. (1998) Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation, 97, 1114-1123.
    • (1998) Circulation , vol.97 , pp. 1114-1123
    • Baumgartner, I.1    Pieczek, A.2    Manor, O.3    Blair, R.4    Kearney, M.5    Walsh, K.6    Isner, J.M.7
  • 5
    • 0028274136 scopus 로고
    • The human immunodeficiency virus type 1 Tat protein transactivates tumor necrosis factor beta gene expression through a TAR-like structure
    • Buonaguro, L., Buonaguro, F.M., Giraldo, G. and Ensoli, B. (1994) The human immunodeficiency virus type 1 Tat protein transactivates tumor necrosis factor beta gene expression through a TAR-like structure. J. Virol., 68, 2677-2682.
    • (1994) J. Virol. , vol.68 , pp. 2677-2682
    • Buonaguro, L.1    Buonaguro, F.M.2    Giraldo, G.3    Ensoli, B.4
  • 6
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet, P. et al. (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature, 380, 435-439.
    • (1996) Nature , vol.380 , pp. 435-439
    • Carmeliet, P.1
  • 7
    • 0025688912 scopus 로고
    • Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity and promotes monocyte migration
    • Clauss, M. et al. (1990) Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity and promotes monocyte migration. J. Exp. Med., 172, 1535-1545.
    • (1990) J. Exp. Med. , vol.172 , pp. 1535-1545
    • Clauss, M.1
  • 8
    • 0030605839 scopus 로고    scopus 로고
    • Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: Functional analysis of the tumor necrosis factor receptors
    • Clauss, M., Grell, M., Fangmann, C., Fiers, W., Scheurich, P. and Risau, W. (1996a) Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: functional analysis of the tumor necrosis factor receptors. FEBS Lett., 390, 334-338.
    • (1996) FEBS Lett. , vol.390 , pp. 334-338
    • Clauss, M.1    Grell, M.2    Fangmann, C.3    Fiers, W.4    Scheurich, P.5    Risau, W.6
  • 9
    • 0029929716 scopus 로고    scopus 로고
    • The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis
    • Clauss, M., Weich, H., Breier, G., Knies, U., Rockl, W., Waltenberger, J. and Risau, W. (1996b) The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J. Biol. Chem., 271, 17629-17634.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17629-17634
    • Clauss, M.1    Weich, H.2    Breier, G.3    Knies, U.4    Rockl, W.5    Waltenberger, J.6    Risau, W.7
  • 10
    • 0024297354 scopus 로고
    • Multiple sequence alignment with hierarchical clustering
    • Corpet, F. (1988) Multiple sequence alignment with hierarchical clustering. Nucleic Acids Res., 16, 10881-10890.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 10881-10890
    • Corpet, F.1
  • 11
    • 0032128035 scopus 로고    scopus 로고
    • Analysis of genomic rearragement and subsequent gene deletion of the attenuated Orf virus strain D1701
    • Cottone, R., Büttner, M., Bauer, B., Henkel, M., Hettich, E. and Rziha, H.-J. (1998) Analysis of genomic rearragement and subsequent gene deletion of the attenuated Orf virus strain D1701. Virus Res., 56, 53-67.
    • (1998) Virus Res. , vol.56 , pp. 53-67
    • Cottone, R.1    Büttner, M.2    Bauer, B.3    Henkel, M.4    Hettich, E.5    Rziha, H.-J.6
  • 12
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
    • de Vries, C., Escobedo, J.A., Ueno, H., Houck, K., Ferrara, N. and Williams, L.T. (1992) The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science, 255, 989-991.
    • (1992) Science , vol.255 , pp. 989-991
    • De Vries, C.1    Escobedo, J.A.2    Ueno, H.3    Houck, K.4    Ferrara, N.5    Williams, L.T.6
  • 13
    • 0030865798 scopus 로고    scopus 로고
    • Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique cellular structure, the invasome
    • Dehio, C., Meyer, M., Berger, J., Schwarz, H. and Lanz, C. (1997) Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique cellular structure, the invasome. J. Cell Sci., 110, 2141-2154.
    • (1997) J. Cell Sci. , vol.110 , pp. 2141-2154
    • Dehio, C.1    Meyer, M.2    Berger, J.3    Schwarz, H.4    Lanz, C.5
  • 14
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara, N. and Davis-Smyth, T. (1997) The biology of vascular endothelial growth factor. Endocrinol. Rev., 18, 4-25.
    • (1997) Endocrinol. Rev. , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 15
    • 0026505773 scopus 로고
    • Molecular and biological properties of the vascular endothelial growth factor family of proteins
    • Ferrara, N., Houck, K., Jakeman, L. and Leung, D.W. (1992) Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocrinol. Rev., 13, 18-32.
    • (1992) Endocrinol. Rev. , vol.13 , pp. 18-32
    • Ferrara, N.1    Houck, K.2    Jakeman, L.3    Leung, D.W.4
  • 17
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Med., 1, 27-31.
    • (1995) Nature Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 18
    • 0032584176 scopus 로고    scopus 로고
    • Therapeutic angiogenesis in ischemic limbs
    • Folkman, J. (1998) Therapeutic angiogenesis in ischemic limbs. Circulation, 97, 1108-1110.
    • (1998) Circulation , vol.97 , pp. 1108-1110
    • Folkman, J.1
  • 19
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong, G.H., Rossant, J., Gertsenstein, M. and Breitman, M.L. (1995) Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature, 376, 66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 23
    • 0028838012 scopus 로고
    • Dimerization of cell surface receptors in signal transduction
    • Heldin, C.H. (1995) Dimerization of cell surface receptors in signal transduction. Cell, 80, 213-223.
    • (1995) Cell , vol.80 , pp. 213-223
    • Heldin, C.H.1
  • 24
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • Hiratsuka, S., Minowa, O., Kuno, J., Noda, T. and Shibuya, M. (1998) Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc. Natl Acad. Sci. USA, 95, 9349-9354.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3    Noda, T.4    Shibuya, M.5
  • 25
    • 0030026897 scopus 로고    scopus 로고
    • A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
    • published erratum appeared 1996 in EMBO J., 15, 1751
    • Joukov, V., Pajusola, K., Kaipainen, A., Chilov, D., Lahtinen, I., Kukk, E., Saksela, O., Kalkkinen, N. and Alitalo, K. (1996) A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J., 15, 290-298 [published erratum appeared 1996 in EMBO J., 15, 1751]
    • (1996) EMBO J. , vol.15 , pp. 290-298
    • Joukov, V.1    Pajusola, K.2    Kaipainen, A.3    Chilov, D.4    Lahtinen, I.5    Kukk, E.S.O.6    Kalkkinen, N.7    Alitalo, K.8
  • 27
    • 0029920944 scopus 로고    scopus 로고
    • Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis
    • Keyt, B.A., Nguyen, H.V., Berleau, L.T., Duarte, C.M., Park, J., Chen, H. and Ferrara (1996) Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis. J. Biol Chem., 271, 5638-5646.
    • (1996) J. Biol Chem. , vol.271 , pp. 5638-5646
    • Keyt, B.A.1    Nguyen, H.V.2    Berleau, L.T.3    Duarte, C.M.4    Park, J.5    Chen, H.6    Ferrara7
  • 28
    • 0030265393 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptors
    • Klagsbrun, M. and D'Amore, P.A. (1996) Vascular endothelial growth factor and its receptors. Cytokine Growth Factor Rev., 7, 259-270.
    • (1996) Cytokine Growth Factor Rev. , vol.7 , pp. 259-270
    • Klagsbrun, M.1    D'Amore, P.A.2
  • 29
    • 0032583125 scopus 로고    scopus 로고
    • Integration of endothelial cells in multicellular spheroides prevents apoptosis and induces differentiation
    • in press
    • Korff, T. and Augustin, H.G. (1998) Integration of endothelial cells in multicellular spheroides prevents apoptosis and induces differentiation. J. Cell Biol., in press.
    • (1998) J. Cell Biol.
    • Korff, T.1    Augustin, H.G.2
  • 30
    • 0031466232 scopus 로고    scopus 로고
    • The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells
    • Kroll, J. and Waltenberger, J. (1997) The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J. Biol. Chem., 272, 32521-32527.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32521-32527
    • Kroll, J.1    Waltenberger, J.2
  • 31
    • 0030453355 scopus 로고    scopus 로고
    • VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
    • Kukk, E., Lymboussaki, A., Taira, S., Kaipainen, A., Jeltsch, M., Joukov, V. and Alitalo, K. (1996) VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development, 122, 3829-3837.
    • (1996) Development , vol.122 , pp. 3829-3837
    • Kukk, E.1    Lymboussaki, A.2    Taira, S.3    Kaipainen, A.4    Jeltsch, M.5    Joukov, V.6    Alitalo, K.7
  • 32
    • 0029962242 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-related protein: A ligand and specific activator of the tyrosine kinase receptor Flt4
    • Lee, J., Gray, A., Yuan, J., Luoh, S.M., Avraham, H. and Wood, W.I. (1996) Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. Proc. Natl Acad. Sci. USA, 93, 1988-1992.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 1988-1992
    • Lee, J.1    Gray, A.2    Yuan, J.3    Luoh, S.M.4    Avraham, H.5    Wood, W.I.6
  • 33
    • 0027979253 scopus 로고
    • Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus
    • Lyttle, D.J., Fraser, K.M., Fleming, S.B., Mercer, A.A. and Robinson, A.J. (1994) Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus. J. Virol., 68, 84-92.
    • (1994) J. Virol. , vol.68 , pp. 84-92
    • Lyttle, D.J.1    Fraser, K.M.2    Fleming, S.B.3    Mercer, A.A.4    Robinson, A.J.5
  • 34
    • 0031940012 scopus 로고    scopus 로고
    • Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart
    • Mack, C.A. et al. (1998) Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart. J. Thorac. Cardiovasc. Surg., 115, 168-176.
    • (1998) J. Thorac. Cardiovasc. Surg. , vol.115 , pp. 168-176
    • Mack, C.A.1
  • 35
    • 0026052391 scopus 로고
    • Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor
    • Maglione, D., Guerriero, V., Viglietto, G., Delli-Bovi, P. and Persico, M.G. (1991) Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc. Natl Acad. Sci. USA, 88, 9267-9271.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 9267-9271
    • Maglione, D.1    Guerriero, V.2    Viglietto, G.3    Delli-Bovi, P.4    Persico, M.G.5
  • 36
    • 0027251256 scopus 로고
    • A structural superfamily of growth factors containing a cystine knot motif
    • McDonald, N.Q. and Hendrickson, W.A. (1993) A structural superfamily of growth factors containing a cystine knot motif. Cell, 73, 421-424.
    • (1993) Cell , vol.73 , pp. 421-424
    • McDonald, N.Q.1    Hendrickson, W.A.2
  • 37
    • 0030795733 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Crystal structure and functional mapping of the kinase domain receptor binding site
    • Muller, Y.A., Li, B., Christinger, H.W., Wells, J.A., Cunningham, B.C. and de Vos, A.M. (1997) Vascular endothelial growth factor: Crystal structure and functional mapping of the kinase domain receptor binding site. Proc. Natl Acad. Sci. USA, 94, 7192-7197.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 7192-7197
    • Muller, Y.A.1    Li, B.2    Christinger, H.W.3    Wells, J.A.4    Cunningham, B.C.5    De Vos, A.M.6
  • 38
    • 0025991563 scopus 로고
    • Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites
    • Myoken, Y., Kayada, Y., Okamoto, T., Kan, M., Sato, G.H. and Sato, J.D. (1991) Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites. Proc. Natl Acad Sci. USA, 88, 5819-5823.
    • (1991) Proc. Natl Acad Sci. USA , vol.88 , pp. 5819-5823
    • Myoken, Y.1    Kayada, Y.2    Okamoto, T.3    Kan, M.4    Sato, G.H.5    Sato, J.D.6
  • 39
    • 0028783414 scopus 로고
    • A novel, microcarrier-based in vitro assay for rapid and reliable quantification of three-dimensional cell migration and angiogenesis
    • Nehls, V. and Drenckhahn, D. (1995) A novel, microcarrier-based in vitro assay for rapid and reliable quantification of three-dimensional cell migration and angiogenesis. Microvasc. Res., 50, 311-322.
    • (1995) Microvasc. Res. , vol.50 , pp. 311-322
    • Nehls, V.1    Drenckhahn, D.2
  • 40
    • 0029782928 scopus 로고    scopus 로고
    • Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform
    • Olofsson, B., Pajusola, K., von Euler, G., Chilov, D., Alitalo, K. and Eriksson, U. (1996) Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform. J. Biol. Chem., 271, 19310-19317.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19310-19317
    • Olofsson, B.1    Pajusola, K.2    Von Euler, G.3    Chilov, D.4    Alitalo, K.5    Eriksson, U.6
  • 41
    • 13144266696 scopus 로고    scopus 로고
    • Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells
    • Olofsson, B. et al. (1998) Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. Proc. Natl Acad. Sci. USA, 95, 11709-11714.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 11709-11714
    • Olofsson, B.1
  • 42
    • 0028134936 scopus 로고
    • Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo and high affinity binding to Flt-1 but not to Flk-1/KDR
    • Park, J.E., Chen, H.H., Winer, J., Houck, K.A. and Ferrara, N. (1994) Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo and high affinity binding to Flt-1 but not to Flk-1/KDR. J. Biol. Chem., 269, 25646-25654.
    • (1994) J. Biol. Chem. , vol.269 , pp. 25646-25654
    • Park, J.E.1    Chen, H.H.2    Winer, J.3    Houck, K.A.4    Ferrara, N.5
  • 43
    • 0025695869 scopus 로고
    • Characterization of the receptor to vasculotropin on bovine adrenal cortex-derived capillary endothelial cells
    • Plouet, J. and Moukadiri, H. (1990) Characterization of the receptor to vasculotropin on bovine adrenal cortex-derived capillary endothelial cells. J. Biol. Chem., 265, 22071-22074.
    • (1990) J. Biol. Chem. , vol.265 , pp. 22071-22074
    • Plouet, J.1    Moukadiri, H.2
  • 45
    • 0027249239 scopus 로고
    • Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
    • Quinn, T.P., Peters, K.G., de Vries, C., Ferrara, N. and Williams, L.T. (1993) Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc. Natl Acad. Sci. USA, 90, 7533-7537.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 7533-7537
    • Quinn, T.P.1    Peters, K.G.2    De Vries, C.3    Ferrara, N.4    Williams, L.T.5
  • 46
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau, W. (1997) Mechanisms of angiogenesis. Nature, 386, 671-674.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 48
    • 0023905973 scopus 로고
    • Changes in the vascular extracellular matrix during embryonic vasculogenesis and angiogenesis
    • Risau, W. and Lemmon, V. (1988) Changes in the vascular extracellular matrix during embryonic vasculogenesis and angiogenesis. Dev. Biol., 125, 441-450.
    • (1988) Dev. Biol. , vol.125 , pp. 441-450
    • Risau, W.1    Lemmon, V.2
  • 49
    • 0031867648 scopus 로고    scopus 로고
    • Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2
    • Roeckl, W., Hecht, D., Sztajer, H., Waltenberger, J., Yayon, A. and Weich, H.A. (1998) Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2. Exp. Cell Res., 241, 161-170.
    • (1998) Exp. Cell Res. , vol.241 , pp. 161-170
    • Roeckl, W.1    Hecht, D.2    Sztajer, H.3    Waltenberger, J.4    Yayon, A.5    Weich, H.A.6
  • 50
    • 0345009442 scopus 로고    scopus 로고
    • Parapoxviruses: Potential alternative vectors for directing the immune response in permissive and non-permissive hosts
    • in press
    • Rziha, H.-J., Henkel, M., Rosita, C., Meyer, M., Dehio, C. and Büttner, M. (1998) Parapoxviruses: Potential alternative vectors for directing the immune response in permissive and non-permissive hosts. J. Biotechnol., in press.
    • (1998) J. Biotechnol.
    • Rziha, H.-J.1    Henkel, M.2    Rosita, C.3    Meyer, M.4    Dehio, C.5    Büttner, M.6
  • 52
    • 0028831760 scopus 로고
    • Improved high-level expression system for eukaryotic genes in Escherichia coli using T7 RNA polymerase and rare ArgtRNAs
    • Schenk, P.M., Baumann, S., Mattes, R. and Steinbiss, H.H. (1995) Improved high-level expression system for eukaryotic genes in Escherichia coli using T7 RNA polymerase and rare ArgtRNAs. Biotechniques, 19, 196-198.
    • (1995) Biotechniques , vol.19 , pp. 196-198
    • Schenk, P.M.1    Baumann, S.2    Mattes, R.3    Steinbiss, H.H.4
  • 53
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger, D.R., Galli, S.J., Dvorak, A.M., Perruzzi, C.A., Harvey, V.S. and Dvorak, H.F. (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science, 219, 983-985.
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 54
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker, S., Takashima, S., Miao, H.Q., Neufeld, G. and Klagsbrun, M. (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell, 92, 735-745.
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 56
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J.D., Higgins, D.G. and Gibson, T.J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res., 22, 4673-4680.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 57
    • 0030695252 scopus 로고    scopus 로고
    • Modulation of growth factor action: Implications for the treatment of cardiovascular diseases
    • Waltenberger, J. (1997) Modulation of growth factor action: implications for the treatment of cardiovascular diseases. Circulation, 96, 4083-4094.
    • (1997) Circulation , vol.96 , pp. 4083-4094
    • Waltenberger, J.1
  • 58
    • 0027997863 scopus 로고
    • Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
    • Waltenberger, J. et al. (1994) Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J. Biol. Chem., 269, 26988-26995.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26988-26995
    • Waltenberger, J.1
  • 59
    • 0029758798 scopus 로고    scopus 로고
    • Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia
    • Waltenberger, J., Mayr, U., Pentz, S. and Hombach, V. (1996) Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia. Circulation, 94, 1647-1654.
    • (1996) Circulation , vol.94 , pp. 1647-1654
    • Waltenberger, J.1    Mayr, U.2    Pentz, S.3    Hombach, V.4
  • 60
    • 0030782410 scopus 로고    scopus 로고
    • Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor
    • Wiesmann, C., Fuh, G., Christinger, H.W., Eigenbrot, C., Wells, J.A. and de Vos, A.M. (1997) Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Cell, 28, 695-704.
    • (1997) Cell , vol.28 , pp. 695-704
    • Wiesmann, C.1    Fuh, G.2    Christinger, H.W.3    Eigenbrot, C.4    Wells, J.A.5    De Vos, A.M.6
  • 62
    • 0024846490 scopus 로고
    • Gangliosides promote the angiogenic response
    • Ziche, M., Alessandri, G. and Gullino, P.M. (1989) Gangliosides promote the angiogenic response. Lab. Invest., 61, 629-634.
    • (1989) Lab. Invest. , vol.61 , pp. 629-634
    • Ziche, M.1    Alessandri, G.2    Gullino, P.M.3
  • 63
    • 0028143547 scopus 로고
    • Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P
    • Ziche, M., Morbidelli, L., Masini, E., Amerini, S., Granger, H.J., Maggi, C.A., Geppetti, P. and Ledda, F. (1994) Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. J. Clin. Invest., 94, 2036-2044.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2036-2044
    • Ziche, M.1    Morbidelli, L.2    Masini, E.3    Amerini, S.4    Granger, H.J.5    Maggi, C.A.6    Geppetti, P.7    Ledda, F.8
  • 64
    • 20244370028 scopus 로고    scopus 로고
    • Placenta growth factor-1 is chemotactic, mitogenic and angiogenic
    • Ziche, M. et al. (1997) Placenta growth factor-1 is chemotactic, mitogenic and angiogenic. Lab. Invest., 76, 517-531.
    • (1997) Lab. Invest. , vol.76 , pp. 517-531
    • Ziche, M.1


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