An emerging role for the mammalian target of rapamycin in "pathological" protein translation: relevance to cocaine addiction

Frontiers in Pharmacology

Volumn 3 FEB, Issue , 2012, Pages

  Dayas, Christopher V ^a   Smith, Doug W ^a   Dunkley, Peter R ^a  

^a HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Addiction; BDNF; Cocaine; Drug; mGluR; mTOR; Plasticity; Relapse

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN; TRICIRIBINE; TYROSINE KINASE RECEPTOR; WORTMANNIN;

ADDICTION; ALCOHOLISM; ARTICLE; BINGE DRINKING; BRAIN REGION; CELL ACTIVITY; COCAINE DEPENDENCE; DENDRITE; DRUG EXPOSURE; DRUG MECHANISM; DRUG SEEKING BEHAVIOR; DRUG SELF ADMINISTRATION; ENZYME ACTIVATION; ENZYME INHIBITION; FACILITATION; HEROIN DEPENDENCE; HUMAN; INTRACELLULAR SIGNALING; LONG TERM DEPRESSION; LONG TERM MEMORY; LONG TERM POTENTIATION; MOLECULAR MECHANICS; NERVE CELL PLASTICITY; NEUROBIOLOGY; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; REGULATORY MECHANISM; SYNAPTIC TRANSMISSION; TRANSLATION INITIATION; VENTRAL TEGMENTUM; WITHDRAWAL SYNDROME;

EID: 84865984316     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00013     Document Type: Article

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