메뉴 건너뛰기




Volumn 39, Issue 4, 2016, Pages 547-554

Yin-Yang 1 and Yin-Yang 2 exert opposing effects on the promoter activity of interleukin 4

Author keywords

Constitutive factor; IL 4; Th2 cell; YY1; YY2

Indexed keywords

CHINESE DRUG; GAMMA INTERFERON; INTERLEUKIN 4; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TRANSCRIPTION FACTOR YY1; DNA BINDING PROTEIN; FIREFLY LUCIFERASE; TRANSCRIPTION FACTOR; YY1 PROTEIN, MOUSE; YY2 PROTEIN, MOUSE; ZINC FINGER PROTEIN;

EID: 84940951091     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-015-0622-7     Document Type: Article
Times cited : (9)

References (49)
  • 1
    • 0037451302 scopus 로고    scopus 로고
    • Transcription factor YY1 functions as a PcG protein in vivo
    • 1:CAS:528:DC%2BD3sXit1yrsLs%3D 12628927 151054
    • Atchison, L., A. Ghias, F. Wilkinson, N. Bonini, and M.L. Atchison. 2003. Transcription factor YY1 functions as a PcG protein in vivo. EMBO Journal 22: 1347-1358.
    • (2003) EMBO Journal , vol.22 , pp. 1347-1358
    • Atchison, L.1    Ghias, A.2    Wilkinson, F.3    Bonini, N.4    Atchison, M.L.5
  • 2
    • 0031026293 scopus 로고    scopus 로고
    • Characterization of the transcriptional regulator YY1. The bipartite transactivation domain is independent of interaction with the TATA box-binding protein, transcription factor IIB, TAFII55, or cAMP-responsive element-binding protein (CPB)-binding protein
    • 1:CAS:528:DyaK2sXls1Gjsg%3D%3D 8999850
    • Austen, M., B. Luscher, and J.M. Luscher-Firzlaff. 1997. Characterization of the transcriptional regulator YY1. The bipartite transactivation domain is independent of interaction with the TATA box-binding protein, transcription factor IIB, TAFII55, or cAMP-responsive element-binding protein (CPB)-binding protein. Journal of Biological Chemistry 272: 1709-1717.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 1709-1717
    • Austen, M.1    Luscher, B.2    Luscher-Firzlaff, J.M.3
  • 4
    • 0031014560 scopus 로고    scopus 로고
    • Functions of IL-4 and control of its expression
    • 1:CAS:528:DyaK2sXhsVOntrw%3D 9034722
    • Brown, M.A., and J. Hural. 1997. Functions of IL-4 and control of its expression. Critical Reviews in Immunology 17: 1-32.
    • (1997) Critical Reviews in Immunology , vol.17 , pp. 1-32
    • Brown, M.A.1    Hural, J.2
  • 5
    • 0032087892 scopus 로고    scopus 로고
    • The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1
    • 1:CAS:528:DyaK1cXktlKktbY%3D 9651589
    • Brown, J.L., D. Mucci, M. Whiteley, M.L. Dirksen, and J.A. Kassis. 1998. The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1. Molecular Cell 1: 1057-1064.
    • (1998) Molecular Cell , vol.1 , pp. 1057-1064
    • Brown, J.L.1    Mucci, D.2    Whiteley, M.3    Dirksen, M.L.4    Kassis, J.A.5
  • 7
    • 0142210174 scopus 로고    scopus 로고
    • +T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: Involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor
    • 1:CAS:528:DC%2BD3sXos1SnsLw%3D 14573767
    • +T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor. Molecular Pharmacology 64: 1169-1179.
    • (2003) Molecular Pharmacology , vol.64 , pp. 1169-1179
    • Chung, S.W.1    Kang, B.Y.2    Kim, T.S.3
  • 8
    • 0032880120 scopus 로고    scopus 로고
    • Targeted disruption of mouse Yin Yang 1 transcription factor results in peri-implantation lethality
    • 1:CAS:528:DyaK1MXmtlalsbc%3D 10490658 84716
    • Donohoe, M.E., X. Zhang, L. Mcginnis, J. Biggers, E. Li, and Y. Shi. 1999. Targeted disruption of mouse Yin Yang 1 transcription factor results in peri-implantation lethality. Molecular and Cellular Biology 19: 7237-7244.
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 7237-7244
    • Donohoe, M.E.1    Zhang, X.2    McGinnis, L.3    Biggers, J.4    Li, E.5    Shi, Y.6
  • 9
    • 0030930486 scopus 로고    scopus 로고
    • Multiple mechanisms of transcriptional repression by YY1
    • 1:CAS:528:DyaK2sXktFOhu7g%3D 9199306 232224
    • Galvin, K.M., and Y. Shi. 1997. Multiple mechanisms of transcriptional repression by YY1. Molecular and Cellular Biology 17: 3723-3732.
    • (1997) Molecular and Cellular Biology , vol.17 , pp. 3723-3732
    • Galvin, K.M.1    Shi, Y.2
  • 10
    • 0037514314 scopus 로고    scopus 로고
    • Yin Yang 1 is a lipopolysaccharide-inducible activator of the murine 3′ Igh enhancer, hs3
    • 1:CAS:528:DC%2BD3sXjvVyntLY%3D 12759432
    • Gordon, S.J., S. Saleque, and B.K. Birshtein. 2003. Yin Yang 1 is a lipopolysaccharide-inducible activator of the murine 3′ Igh enhancer, hs3. The Journal of Immunology 170: 5549-5557.
    • (2003) The Journal of Immunology , vol.170 , pp. 5549-5557
    • Gordon, S.J.1    Saleque, S.2    Birshtein, B.K.3
  • 11
    • 33644507479 scopus 로고    scopus 로고
    • Transcription factor YY1: Structure, function, and therapeutic implications in cancer biology
    • 1:CAS:528:DC%2BD28Xhs1Kis7c%3D 16314846
    • Gordon, S., G. Akopyan, H. Garban, and B. Bonavida. 2006. Transcription factor YY1: structure, function, and therapeutic implications in cancer biology. Oncogene 25: 1125-1142.
    • (2006) Oncogene , vol.25 , pp. 1125-1142
    • Gordon, S.1    Akopyan, G.2    Garban, H.3    Bonavida, B.4
  • 14
    • 46049100204 scopus 로고    scopus 로고
    • Yin-Yang 1 regulates effector cytokine gene expression and T(H)2 immune responses
    • 1:CAS:528:DC%2BD1cXotlajtrg%3D 18423564
    • Guo, J., X. Lin, M.A. Williams, Q. Hamid, and S.N. Georas. 2008. Yin-Yang 1 regulates effector cytokine gene expression and T(H)2 immune responses. Journal of Allergy and Clinical Immunology 122: 195-201.
    • (2008) Journal of Allergy and Clinical Immunology , vol.122 , pp. 195-201
    • Guo, J.1    Lin, X.2    Williams, M.A.3    Hamid, Q.4    Georas, S.N.5
  • 15
    • 34447262102 scopus 로고    scopus 로고
    • The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation
    • 1:CAS:528:DC%2BD2sXoslSis78%3D 17640524 2034312
    • He, Y., J. Dupree, J. Wang, J. Sandoval, J. Li, H. Liu, Y. Shi, K.A. Nave, and P. Casaccia-Bonnefil. 2007. The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron 55: 217-230.
    • (2007) Neuron , vol.55 , pp. 217-230
    • He, Y.1    Dupree, J.2    Wang, J.3    Sandoval, J.4    Li, J.5    Liu, H.6    Shi, Y.7    Nave, K.A.8    Casaccia-Bonnefil, P.9
  • 17
    • 0030604714 scopus 로고    scopus 로고
    • The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
    • 1:CAS:528:DyaK28XjvF2iurk%3D 8674125
    • Ho, I.C., M.R. Hodge, J.W. Rooney, and L.H. Glimcher. 1996. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85: 973-983.
    • (1996) Cell , vol.85 , pp. 973-983
    • Ho, I.C.1    Hodge, M.R.2    Rooney, J.W.3    Glimcher, L.H.4
  • 19
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • 1:CAS:528:DyaK28XhvFeqsLs%3D 8624821
    • Kaplan, M.H., U. Schindler, S.T. Smiley, and M.J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4: 313-319.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 20
    • 0035469827 scopus 로고    scopus 로고
    • Regulation of interferon-gamma gene expression by nuclear factor of activated T cells
    • 1:CAS:528:DC%2BD3MXmvFGjtLo%3D 11520798
    • Kiani, A., F.J. Garcia-Cozar, I. Habermann, S. Laforsch, T. Aebischer, G. Ehninger, and A. Rao. 2001. Regulation of interferon-gamma gene expression by nuclear factor of activated T cells. Blood 98: 1480-1488.
    • (2001) Blood , vol.98 , pp. 1480-1488
    • Kiani, A.1    Garcia-Cozar, F.J.2    Habermann, I.3    Laforsch, S.4    Aebischer, T.5    Ehninger, G.6    Rao, A.7
  • 21
    • 34250894949 scopus 로고    scopus 로고
    • Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1
    • 1:CAS:528:DC%2BD2sXnvVaiurg%3D 17478514 1904287
    • Kim, J.D., C. Faulk, and J. Kim. 2007. Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1. Nucleic Acids Research 35: 3442-3452.
    • (2007) Nucleic Acids Research , vol.35 , pp. 3442-3452
    • Kim, J.D.1    Faulk, C.2    Kim, J.3
  • 23
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • 1:CAS:528:DyaL1MXit12lsbk%3D 2523712
    • Mosmann, T.R., and R.L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annual Review of Immunology 7: 145-173.
    • (1989) Annual Review of Immunology , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 24
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • 1:CAS:528:DyaL28XhvVClsbk%3D 2419430
    • Mosmann, T.R., H. Cherwinski, M.W. Bond, M.A. Giedlin, and R.L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. The Journal of Immunology 136: 2348-2357.
    • (1986) The Journal of Immunology , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 25
    • 2942567557 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of the transcription factor YY2
    • 1:CAS:528:DC%2BD2cXksFygurs%3D 15087442
    • Nguyen, N., X. Zhang, N. Olashaw, and E. Seto. 2004. Molecular cloning and functional characterization of the transcription factor YY2. Journal of Biological Chemistry 279: 25927-25934.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 25927-25934
    • Nguyen, N.1    Zhang, X.2    Olashaw, N.3    Seto, E.4
  • 26
    • 0034789109 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation of transcription factor Yin Yang 1 under conditions of DNA damage
    • 1:CAS:528:DC%2BD3MXkvVOltbw%3D 11437367
    • Oei, S.L., and Y. Shi. 2001. Poly(ADP-ribosyl)ation of transcription factor Yin Yang 1 under conditions of DNA damage. Biochemical and Biophysical Research Communications 285: 27-31.
    • (2001) Biochemical and Biophysical Research Communications , vol.285 , pp. 27-31
    • Oei, S.L.1    Shi, Y.2
  • 29
    • 0035896625 scopus 로고    scopus 로고
    • Interaction between YY1 and the retinoblastoma protein. Regulation of cell cycle progression in differentiated cells
    • 1:CAS:528:DC%2BD3MXitFKhu78%3D 11118439
    • Petkova, V., M.J. Romanowski, I. Sulijoadikusumo, D. Rohne, P. Kang, T. Shenk, and A. Usheva. 2001. Interaction between YY1 and the retinoblastoma protein. Regulation of cell cycle progression in differentiated cells. Journal of Biological Chemistry 276: 7932-7936.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 7932-7936
    • Petkova, V.1    Romanowski, M.J.2    Sulijoadikusumo, I.3    Rohne, D.4    Kang, P.5    Shenk, T.6    Usheva, A.7
  • 30
    • 0028670837 scopus 로고
    • Characterization of FIII/YY1, a Xenopus laevis conserved zinc-finger protein binding to the first exon of L1 and L14 ribosomal protein genes
    • 1:CAS:528:DyaK2MXivVWlu7g%3D 7802655
    • Pisaneschi, G., S. Ceccotti, M.L. Falchetti, S. Fiumicino, F. Carnevali, and E. Beccari. 1994. Characterization of FIII/YY1, a Xenopus laevis conserved zinc-finger protein binding to the first exon of L1 and L14 ribosomal protein genes. Biochemical and Biophysical Research Communications 205: 1236-1242.
    • (1994) Biochemical and Biophysical Research Communications , vol.205 , pp. 1236-1242
    • Pisaneschi, G.1    Ceccotti, S.2    Falchetti, M.L.3    Fiumicino, S.4    Carnevali, F.5    Beccari, E.6
  • 33
    • 0027373948 scopus 로고
    • Interaction between transcription factors Sp1 and YY1
    • 1:CAS:528:DyaK3sXmtF2ju7k%3D 8003102
    • Seto, E., B. Lewis, and T. Shenk. 1993. Interaction between transcription factors Sp1 and YY1. Nature 365: 462-464.
    • (1993) Nature , vol.365 , pp. 462-464
    • Seto, E.1    Lewis, B.2    Shenk, T.3
  • 34
    • 0025943945 scopus 로고
    • Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein
    • 1:CAS:528:DyaK3sXhslWhtA%3D%3D 1655281
    • Shi, Y., E. Seto, L.S. Chang, and T. Shenk. 1991. Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein. Cell 67: 377-388.
    • (1991) Cell , vol.67 , pp. 377-388
    • Shi, Y.1    Seto, E.2    Chang, L.S.3    Shenk, T.4
  • 35
    • 0030941901 scopus 로고    scopus 로고
    • Everything you have ever wanted to know about Yin Yang 1
    • 1:CAS:528:DyaK2sXhvFWiu7w%3D 9141463
    • Shi, Y., J.S. Lee, and K.M. Galvin. 1997. Everything you have ever wanted to know about Yin Yang 1. Biochimica et Biophysica Acta 1332: F49-F66.
    • (1997) Biochimica et Biophysica Acta , vol.1332 , pp. F49-F66
    • Shi, Y.1    Lee, J.S.2    Galvin, K.M.3
  • 36
    • 0027745645 scopus 로고
    • Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc
    • 1:CAS:528:DyaK2cXkslegsA%3D%3D 8266081
    • Shrivastava, A., S. Saleque, G.V. Kalpana, S. Artandi, S.P. Goff, and K. Calame. 1993. Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc. Science 262: 1889-1892.
    • (1993) Science , vol.262 , pp. 1889-1892
    • Shrivastava, A.1    Saleque, S.2    Kalpana, G.V.3    Artandi, S.4    Goff, S.P.5    Calame, K.6
  • 37
    • 39449133957 scopus 로고    scopus 로고
    • A mechanism for the initiation of allergen-induced T helper type 2 responses
    • 1:CAS:528:DC%2BD1cXitVOjsbo%3D 18300366 3888112
    • Sokol, C.L., G.M. Barton, A.G. Farr, and R. Medzhitov. 2008. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nature Immunology 9: 310-318.
    • (2008) Nature Immunology , vol.9 , pp. 310-318
    • Sokol, C.L.1    Barton, G.M.2    Farr, A.G.3    Medzhitov, R.4
  • 38
    • 0030030331 scopus 로고    scopus 로고
    • Polymorphic nucleotides within the human IL-4 promoter that mediate overexpression of the gene
    • 1:CAS:528:DyaK28XksV2muw%3D%3D 8543789
    • Song, Z., V. Casolaro, R. Chen, S.N. Georas, D. Monos, and S.J. Ono. 1996. Polymorphic nucleotides within the human IL-4 promoter that mediate overexpression of the gene. The Journal of Immunology 156: 424-429.
    • (1996) The Journal of Immunology , vol.156 , pp. 424-429
    • Song, Z.1    Casolaro, V.2    Chen, R.3    Georas, S.N.4    Monos, D.5    Ono, S.J.6
  • 39
    • 0027132107 scopus 로고
    • IL4 dictates T-cell differentiation
    • 1:CAS:528:DyaK2cXhvVyqsbY%3D 7905654
    • Swain, S.L. 1993. IL4 dictates T-cell differentiation. Research in Immunology 144: 616-620.
    • (1993) Research in Immunology , vol.144 , pp. 616-620
    • Swain, S.L.1
  • 40
    • 0032567436 scopus 로고    scopus 로고
    • The roles of nuclear factor of activated T cells and ying-yang 1 in activation-induced expression of the interferon-gamma promoter in T cells
    • 1:CAS:528:DyaK1MXisFWktA%3D%3D 9857002
    • Sweetser, M.T., T. Hoey, Y.L. Sun, W.M. Weaver, G.A. Price, and C.B. Wilson. 1998. The roles of nuclear factor of activated T cells and ying-yang 1 in activation-induced expression of the interferon-gamma promoter in T cells. Journal of Biological Chemistry 273: 34775-34783.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 34775-34783
    • Sweetser, M.T.1    Hoey, T.2    Sun, Y.L.3    Weaver, W.M.4    Price, G.A.5    Wilson, C.B.6
  • 41
    • 0032819331 scopus 로고    scopus 로고
    • Unlocking the mechanisms of transcription factor YY1: Are chromatin modifying enzymes the key?
    • 1:CAS:528:DyaK1MXlt1Shsro%3D 10452940
    • Thomas, M.J., and E. Seto. 1999. Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key? Gene 236: 197-208.
    • (1999) Gene , vol.236 , pp. 197-208
    • Thomas, M.J.1    Seto, E.2
  • 42
    • 31544470129 scopus 로고    scopus 로고
    • A role for Ets1, synergizing with AP-1 and GATA-3 in the regulation of IL-5 transcription in mouse Th2 lymphocytes
    • 1:CAS:528:DC%2BD28XovVGisg%3D%3D 16373364
    • Wang, J., M.F. Shannon, and I.G. Young. 2006. A role for Ets1, synergizing with AP-1 and GATA-3 in the regulation of IL-5 transcription in mouse Th2 lymphocytes. International Immunology 18: 313-323.
    • (2006) International Immunology , vol.18 , pp. 313-323
    • Wang, J.1    Shannon, M.F.2    Young, I.G.3
  • 45
    • 0028892445 scopus 로고
    • High affinity YY1 binding motifs: Identification of two core types (ACAT and CCAT) and distribution of potential binding sites within the human beta globin cluster
    • 1:CAS:528:DyaK2MXpslensLk%3D 7501456 307390
    • Yant, S.R., W. Zhu, D. Millinoff, J.L. Slightom, M. Goodman, and D.L. Gumucio. 1995. High affinity YY1 binding motifs: identification of two core types (ACAT and CCAT) and distribution of potential binding sites within the human beta globin cluster. Nucleic Acids Research 23: 4353-4362.
    • (1995) Nucleic Acids Research , vol.23 , pp. 4353-4362
    • Yant, S.R.1    Zhu, W.2    Millinoff, D.3    Slightom, J.L.4    Goodman, M.5    Gumucio, D.L.6
  • 46
    • 0034905085 scopus 로고    scopus 로고
    • Regulation of transcription factor YY1 by acetylation and deacetylation
    • 1:CAS:528:DC%2BD3MXlvF2htL0%3D 11486036 87316
    • Yao, Y.L., W.M. Yang, and E. Seto. 2001. Regulation of transcription factor YY1 by acetylation and deacetylation. Molecular and Cellular Biology 21: 5979-5991.
    • (2001) Molecular and Cellular Biology , vol.21 , pp. 5979-5991
    • Yao, Y.L.1    Yang, W.M.2    Seto, E.3
  • 47
    • 0029740336 scopus 로고    scopus 로고
    • The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: Inhibition of AP1 binding and activation of a silencer element
    • 1:CAS:528:DyaK28XltFKjsLs%3D 8756632 231475
    • Ye, J., M. Cippitelli, L. Dorman, J.R. Ortaldo, and H.A. Young. 1996. The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: inhibition of AP1 binding and activation of a silencer element. Molecular and Cellular Biology 16: 4744-4753.
    • (1996) Molecular and Cellular Biology , vol.16 , pp. 4744-4753
    • Ye, J.1    Cippitelli, M.2    Dorman, L.3    Ortaldo, J.R.4    Young, H.A.5
  • 48
    • 0030764961 scopus 로고    scopus 로고
    • Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
    • 1:CAS:528:DyaK2sXls1Ois70%3D 9261181
    • Zhang, D.H., L. Cohn, P. Ray, K. Bottomly, and A. Ray. 1997. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. Journal of Biological Chemistry 272: 21597-21603.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 21597-21603
    • Zhang, D.H.1    Cohn, L.2    Ray, P.3    Bottomly, K.4    Ray, A.5
  • 49
    • 0029052418 scopus 로고
    • Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB
    • 1:CAS:528:DyaK2MXmt1agsr4%3D 7769693 189172
    • Zhou, Q., R.W. Gedrich, and D.A. Engel. 1995. Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB. Journal of Virology 69: 4323-4330.
    • (1995) Journal of Virology , vol.69 , pp. 4323-4330
    • Zhou, Q.1    Gedrich, R.W.2    Engel, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.