-
1
-
-
0032006678
-
The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways
-
Kelly, J. W. The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways. Curr Opin Struct Biol 8, 101-6 (1998).
-
(1998)
Curr Opin Struct Biol
, vol.8
, pp. 101-106
-
-
Kelly, J.W.1
-
2
-
-
0344944630
-
Protein aggregation and aggregate toxicity: New insights into protein folding, misfolding diseases and biological evolution
-
Stefani, M. & Dobson, C. M. Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J Mol Med (Berl) 81, 678-99 (2003).
-
(2003)
J Mol Med (Berl)
, vol.81
, pp. 678-699
-
-
Stefani, M.1
Dobson, C.M.2
-
3
-
-
80155209561
-
Misfolded proteins in Alzheimer's disease and type II diabetes
-
DeToma, A. S., Salamekh, S., Ramamoorthy, A. & Lim, M. H. Misfolded proteins in Alzheimer's disease and type II diabetes. Chem Soc Rev 41, 608-21 (2012).
-
(2012)
Chem Soc Rev
, vol.41
, pp. 608-621
-
-
DeToma, A.S.1
Salamekh, S.2
Ramamoorthy, A.3
Lim, M.H.4
-
4
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini, M. et al. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416, 507-11 (2002).
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
-
5
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti, F. & Dobson, C. M. Protein misfolding, functional amyloid, and human disease. Annual Review of Biochemistry 75, 333-366 (2006).
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
6
-
-
79953287059
-
Amyloid oligomer neurotoxicity calcium dysregulation and lipid rafts
-
Malchiodi-Albedi, F., Paradisi, S., Matteucci, A., Frank, C. & Diociaiuti, M. Amyloid oligomer neurotoxicity, calcium dysregulation, and lipid rafts. Int J Alzheimers Dis 2011, 906964 (2011).
-
(2011)
Int J Alzheimers Dis
, vol.2011
, pp. 906964
-
-
Malchiodi-Albedi, F.1
Paradisi, S.2
Matteucci, A.3
Frank, C.4
Diociaiuti, M.5
-
7
-
-
0034090046
-
Conformational transitions and fibrillation mechanism of human calcitonin as studied by high-resolution solid-state 13c nmr
-
Kamihira, M., Naito, A., Tuzi, S., Nosaka, A. Y. & Saito, H. Conformational transitions and fibrillation mechanism of human calcitonin as studied by high-resolution solid-state 13C NMR. Protein Sci 9, 867-77 (2000).
-
(2000)
Protein Sci
, vol.9
, pp. 867-877
-
-
Kamihira, M.1
Naito, A.2
Tuzi, S.3
Nosaka, A.Y.4
Saito, H.5
-
8
-
-
84922320946
-
How our bodies fight amyloidosis: Effects of physiological factors on pathogenic aggregation of amyloidogenic proteins
-
Huang, L., Liu, X., Cheng, B. & Huang, K. How our bodies fight amyloidosis: effects of physiological factors on pathogenic aggregation of amyloidogenic proteins. Arch Biochem Biophys 568, 46-55 (2015).
-
(2015)
Arch Biochem Biophys
, vol.568
, pp. 46-55
-
-
Huang, L.1
Liu, X.2
Cheng, B.3
Huang, K.4
-
9
-
-
84902105470
-
In search of aggregation pathways of iapp and other amyloidogenic proteins: Finding answers through nmr spectroscopy
-
Patel, H. R., Pithadia, A. S., Brender, J. R., Fierke, C. A. & Ramamoorthy, A. In Search of Aggregation Pathways of IAPP and Other Amyloidogenic Proteins: Finding Answers through NMR Spectroscopy. The Journal of Physical Chemistry Letters 5, 1864-1870 (2014).
-
(2014)
The Journal of Physical Chemistry Letters
, vol.5
, pp. 1864-1870
-
-
Patel, H.R.1
Pithadia, A.S.2
Brender, J.R.3
Fierke, C.A.4
Ramamoorthy, A.5
-
10
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from abeta1-42 are potent central nervous system neurotoxins
-
Lambert, M. P. et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA 95, 6448-53 (1998).
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
-
11
-
-
84903881648
-
Native metastable prefibrillar oligomers are the most neurotoxic species among amyloid aggregates
-
Diociaiuti, M. et al. Native metastable prefibrillar oligomers are the most neurotoxic species among amyloid aggregates. Biochim Biophys Acta 1842, 1622-9 (2014).
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 1622-1629
-
-
Diociaiuti, M.1
-
12
-
-
84907220929
-
Differences between amyloid-beta aggregation in solution and on the membrane: Insights into elucidation of the mechanistic details of Alzheimer's disease
-
Kotler, S. A., Walsh, P., Brender, J. R. & Ramamoorthy, A. Differences between amyloid-beta aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease. Chem Soc Rev 43, 6692-700 (2014).
-
(2014)
Chem Soc Rev
, vol.43
, pp. 6692-6700
-
-
Kotler, S.A.1
Walsh, P.2
Brender, J.R.3
Ramamoorthy, A.4
-
13
-
-
84880381598
-
Structural characterization and inhibition of toxic amyloid-beta oligomeric intermediates
-
Ramamoorthy, A. & Lim, M. H. Structural characterization and inhibition of toxic amyloid-beta oligomeric intermediates. Biophys J 105, 287-8 (2013).
-
(2013)
Biophys J
, vol.105
, pp. 287-288
-
-
Ramamoorthy, A.1
Lim, M.H.2
-
14
-
-
71949086967
-
Molecular pathogenesis of protein misfolding diseases: Pathological molecular environments versus quality control systems against misfolded proteins
-
Naiki, H. & Nagai, Y. Molecular pathogenesis of protein misfolding diseases: pathological molecular environments versus quality control systems against misfolded proteins. J Biochem 146, 751-6 (2009).
-
(2009)
J Biochem
, vol.146
, pp. 751-756
-
-
Naiki, H.1
Nagai, Y.2
-
15
-
-
0028916920
-
Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium
-
Mattson, M. P. & Goodman, Y. Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium. Brain Res 676, 219-24 (1995).
-
(1995)
Brain Res
, vol.676
, pp. 219-224
-
-
Mattson, M.P.1
Goodman, Y.2
-
16
-
-
84858632761
-
Membrane disruption and early events in the aggregation of the diabetes related peptide iapp from a molecular perspective
-
Brender, J. R., Salamekh, S. & Ramamoorthy, A. Membrane Disruption and Early Events in the Aggregation of the Diabetes Related Peptide IAPP from a Molecular Perspective. Accounts of Chemical Research 45, 454-462 (2012).
-
(2012)
Accounts of Chemical Research
, vol.45
, pp. 454-462
-
-
Brender, J.R.1
Salamekh, S.2
Ramamoorthy, A.3
-
17
-
-
84884769320
-
Inhibiting toxic aggregation of amyloidogenic proteins: A therapeutic strategy for protein misfolding diseases
-
Cheng, B. et al. Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases. Biochim Biophys Acta 1830, 4860-71 (2013).
-
(2013)
Biochim Biophys Acta
, vol.1830
, pp. 4860-4871
-
-
Cheng, B.1
-
18
-
-
0032726789
-
Calcitonin
-
Sexton, P. M., Findlay, D. M. & Martin, T. J. Calcitonin. Current Medicinal Chemistry 6, 1067-1093 (1999).
-
(1999)
Current Medicinal Chemistry
, vol.6
, pp. 1067-1093
-
-
Sexton, P.M.1
Findlay, D.M.2
Martin, T.J.3
-
19
-
-
0036251168
-
Forty years of calcitonin-where are we now? A tribute to the work of iain macintyre frs
-
Zaidi, M., Inzerillo, A. M., Moonga, B. S., Bevis, P. J. & Huang, C. L. Forty years of calcitonin-where are we now? A tribute to the work of Iain Macintyre, FRS. Bone 30, 655-63 (2002).
-
(2002)
Bone
, vol.30
, pp. 655-663
-
-
Zaidi, M.1
Inzerillo, A.M.2
Moonga, B.S.3
Bevis, P.J.4
Huang, C.L.5
-
20
-
-
0037093402
-
Diagnosis and treatment of paget's disease of bone
-
Schneider, D., Hofmann, M. T. & Peterson, J. A. Diagnosis and treatment of Paget's disease of bone. Am Fam Physician 65, 2069-72 (2002).
-
(2002)
Am Fam Physician
, vol.65
, pp. 2069-2072
-
-
Schneider, D.1
Hofmann, M.T.2
Peterson, J.A.3
-
21
-
-
0027480757
-
The structure and mechanism of formation of human calcitonin fibrils
-
Arvinte, T., Cudd, A. & Drake, A. F. The structure and mechanism of formation of human calcitonin fibrils. J Biol Chem 268, 6415-22 (1993).
-
(1993)
J Biol Chem
, vol.268
, pp. 6415-6422
-
-
Arvinte, T.1
Cudd, A.2
Drake, A.F.3
-
22
-
-
0037045859
-
A brief history of calcitonin
-
Colman, E., Hedin, R., Swann, J. & Orloff, D. A brief history of calcitonin. Lancet 359, 885-6 (2002).
-
(2002)
Lancet
, vol.359
, pp. 885-886
-
-
Colman, E.1
Hedin, R.2
Swann, J.3
Orloff, D.4
-
23
-
-
0017226393
-
Characterization of amyloid fibril proteins from medullary carcinoma of the thyroid
-
Sletten, K., Westermark, P. & Natvig, J. B. Characterization of amyloid fibril proteins from medullary carcinoma of the thyroid. J Exp Med 143, 993-8 (1976).
-
(1976)
J Exp Med
, vol.143
, pp. 993-998
-
-
Sletten, K.1
Westermark, P.2
Natvig, J.B.3
-
24
-
-
0023684098
-
Calcitonin and chromogranin a localization in medullary carcinoma of the thyroid by immunoelectron microscopy
-
Silver, M. M., Hearn, S. A., Lines, L. D. & Troster, M. Calcitonin and chromogranin A localization in medullary carcinoma of the thyroid by immunoelectron microscopy. J Histochem Cytochem 36, 1031-6 (1988).
-
(1988)
J Histochem Cytochem
, vol.36
, pp. 1031-1036
-
-
Silver, M.M.1
Hearn, S.A.2
Lines, L.D.3
Troster, M.4
-
25
-
-
78951482692
-
Converting the highly amyloidogenic human calcitonin into a powerful fibril inhibitor by three-dimensional structure homology with a non-Amyloidogenic analogue
-
Andreotti, G. et al. Converting the highly amyloidogenic human calcitonin into a powerful fibril inhibitor by three-dimensional structure homology with a non-Amyloidogenic analogue. J Biol Chem 286, 2707-18 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 2707-2718
-
-
Andreotti, G.1
-
26
-
-
0029018348
-
Enhanced potency of human calcitonin when fibrillation is avoided
-
Cudd, A., Arvinte, T., Das, R. E., Chinni, C. & MacIntyre, I. Enhanced potency of human calcitonin when fibrillation is avoided. J Pharm Sci 84, 717-9 (1995).
-
(1995)
J Pharm Sci
, vol.84
, pp. 717-719
-
-
Cudd, A.1
Arvinte, T.2
Das, R.E.3
Chinni, C.4
MacIntyre, I.5
-
27
-
-
0020451794
-
Calcitonin-induced anorexia in rats: A structure-Activity study by intraventricular injections
-
Yamamoto, Y., Nakamuta, H., Koida, M., Seyler, J. K. & Orlowski, R. C. Calcitonin-induced anorexia in rats: a structure-Activity study by intraventricular injections. Jpn J Pharmacol 32, 1013-7 (1982).
-
(1982)
Jpn J Pharmacol
, vol.32
, pp. 1013-1017
-
-
Yamamoto, Y.1
Nakamuta, H.2
Koida, M.3
Seyler, J.K.4
Orlowski, R.C.5
-
28
-
-
0018758729
-
Effect of calcitonin on bone lesions in chronic dialysis patients
-
Feletti, C. & Bonomini, V. Effect of calcitonin on bone lesions in chronic dialysis patients. Nephron 24, 85-8 (1979).
-
(1979)
Nephron
, vol.24
, pp. 85-88
-
-
Feletti, C.1
Bonomini, V.2
-
29
-
-
84880626988
-
Nanomaterials for reducing amyloid cytotoxicity
-
Zhang, M. et al. Nanomaterials for reducing amyloid cytotoxicity. Adv Mater 25, 3780-801 (2013).
-
(2013)
Adv Mater
, vol.25
, pp. 3780-3801
-
-
Zhang, M.1
-
30
-
-
36048952658
-
Backbone-modified amylin derivatives: Implications for amyloid inhibitor design and as template for self-Assembling bionanomaterials
-
Elgersma, R. C., Posthuma, G., Rijkers, D. T. & Liskamp, R. M. Backbone-modified amylin derivatives: implications for amyloid inhibitor design and as template for self-Assembling bionanomaterials. J Pept Sci 13, 709-16 (2007).
-
(2007)
J Pept Sci
, vol.13
, pp. 709-716
-
-
Elgersma, R.C.1
Posthuma, G.2
Rijkers, D.T.3
Liskamp, R.M.4
-
31
-
-
84908405947
-
Synthetic flavonoids aminoisoflavones: Interaction and reactivity with metal-free and metal-Associated amyloid-beta species
-
DeToma, A. S. et al. Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-beta Species. Chem Sci 5, 4851-4862 (2014).
-
(2014)
Chem Sci
, vol.5
, pp. 4851-4862
-
-
DeToma, A.S.1
-
32
-
-
84899083584
-
A small molecule that displays marked reactivity toward copper-versus zinc-Amyloid-beta implicated in Alzheimer's disease
-
Savelieff, M. G. et al. A small molecule that displays marked reactivity toward copper-versus zinc-Amyloid-beta implicated in Alzheimer's disease. Chem Commun (Camb) 50, 5301-3 (2014).
-
(2014)
Chem Commun (Camb)
, vol.50
, pp. 5301-5303
-
-
Savelieff, M.G.1
-
33
-
-
78650669293
-
Design of small molecules that target metal-A{beta} species and regulate metal-induced a{beta} aggregation and neurotoxicity
-
Choi, J. S., Braymer, J. J., Nanga, R. P., Ramamoorthy, A. & Lim, M. H. Design of small molecules that target metal-A{beta} species and regulate metal-induced A{beta} aggregation and neurotoxicity. Proc Natl Acad Sci USA 107, 21990-5 (2010).
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21990-21995
-
-
Choi, J.S.1
Braymer, J.J.2
Nanga, R.P.3
Ramamoorthy, A.4
Lim, M.H.5
-
34
-
-
84875646652
-
Proanthocyanidins are the major anti-diabetic components of cinnamon water extract
-
Jiao, L. et al. Proanthocyanidins are the major anti-diabetic components of cinnamon water extract. Food Chem Toxicol 56, 398-405 (2013).
-
(2013)
Food Chem Toxicol
, vol.56
, pp. 398-405
-
-
Jiao, L.1
-
35
-
-
84874797283
-
Salvianolic acid b inhibits the amyloid formation of human islet amyloid polypeptide and protects pancreatic beta-cells against cytotoxicity
-
Cheng, B. et al. Salvianolic acid B inhibits the amyloid formation of human islet amyloid polypeptide and protects pancreatic beta-cells against cytotoxicity. Proteins 81, 613-21 (2013).
-
(2013)
Proteins
, vol.81
, pp. 613-621
-
-
Cheng, B.1
-
36
-
-
84908265684
-
Natural product agonists of peroxisome proliferator-Activated receptor gamma (ppargamma): A review
-
Wang, L. et al. Natural product agonists of peroxisome proliferator-Activated receptor gamma (PPARgamma): a review. Biochem Pharmacol 92, 73-89 (2014).
-
(2014)
Biochem Pharmacol
, vol.92
, pp. 73-89
-
-
Wang, L.1
-
37
-
-
77957318362
-
Honokiol and magnolol as multifunctional antioxidative molecules for dermatologic disorders
-
Shen, J. L. et al. Honokiol and magnolol as multifunctional antioxidative molecules for dermatologic disorders. Molecules 15, 6452-65 (2010).
-
(2010)
Molecules
, vol.15
, pp. 6452-6465
-
-
Shen, J.L.1
-
38
-
-
0028029275
-
Biphenyl compounds are hydroxyl radical scavengers: Their effective inhibition for uv-induced mutation in salmonella typhimurium ta102
-
Fujita, S. & Taira, J. Biphenyl compounds are hydroxyl radical scavengers: their effective inhibition for UV-induced mutation in Salmonella typhimurium TA102. Free Radic Biol Med 17, 273-7 (1994).
-
(1994)
Free Radic Biol Med
, vol.17
, pp. 273-277
-
-
Fujita, S.1
Taira, J.2
-
39
-
-
84889567429
-
The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy
-
Liu, Y. et al. The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy. Sci Rep 3, 3098 (2013).
-
(2013)
Sci Rep
, vol.3
, pp. 3098
-
-
Liu, Y.1
-
40
-
-
0037144424
-
Amyloid fibril formation by pentapeptide and tetrapeptide fragments of human calcitonin
-
Reches, M., Porat, Y. & Gazit, E. Amyloid fibril formation by pentapeptide and tetrapeptide fragments of human calcitonin. J Biol Chem 277, 35475-80 (2002).
-
(2002)
J Biol Chem
, vol.277
, pp. 35475-35480
-
-
Reches, M.1
Porat, Y.2
Gazit, E.3
-
41
-
-
84893091725
-
Synthesis of tetrahydrohonokiol derivates and their evaluation for cytotoxic activity against ccrf-cem leukemia u251 glioblastoma and hct-116 colon cancer cells
-
Bernaskova, M. et al. Synthesis of tetrahydrohonokiol derivates and their evaluation for cytotoxic activity against CCRF-CEM leukemia, U251 glioblastoma and HCT-116 colon cancer cells. Molecules 19, 1223-37 (2014).
-
(2014)
Molecules
, vol.19
, pp. 1223-1237
-
-
Bernaskova, M.1
-
42
-
-
34548699687
-
Effects of honokiol and magnolol on acute and inflammatory pain models in mice
-
Lin, Y. R., Chen, H. H., Ko, C. H. & Chan, M. H. Effects of honokiol and magnolol on acute and inflammatory pain models in mice. Life Sci 81, 1071-8 (2007).
-
(2007)
Life Sci
, vol.81
, pp. 1071-1078
-
-
Lin, Y.R.1
Chen, H.H.2
Ko, C.H.3
Chan, M.H.4
-
43
-
-
34548764511
-
Honokiol a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis
-
Munroe, M. E., Arbiser, J. L. & Bishop, G. A. Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis. J Immunol 179, 753-63 (2007).
-
(2007)
J Immunol
, vol.179
, pp. 753-763
-
-
Munroe, M.E.1
Arbiser, J.L.2
Bishop, G.A.3
-
44
-
-
33646135325
-
Neuroprotective activity of honokiol and magnolol in cerebellar granule cell damage
-
Lin, Y. R., Chen, H. H., Ko, C. H. & Chan, M. H. Neuroprotective activity of honokiol and magnolol in cerebellar granule cell damage. Eur J Pharmacol 537, 64-9 (2006).
-
(2006)
Eur J Pharmacol
, vol.537
, pp. 64-69
-
-
Lin, Y.R.1
Chen, H.H.2
Ko, C.H.3
Chan, M.H.4
-
45
-
-
78649413538
-
Neuroprotective effect of honokiol and magnolol, compounds from magnolia officinalis, on beta-Amyloid-induced toxicity in pc12 cells
-
Hoi, C. P., Ho, Y. P., Baum, L. & Chow, A. H. Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-Amyloid-induced toxicity in PC12 cells. Phytother Res 24, 1538-42 (2010).
-
(2010)
Phytother Res
, vol.24
, pp. 1538-1542
-
-
Hoi, C.P.1
Ho, Y.P.2
Baum, L.3
Chow, A.H.4
-
46
-
-
84874933357
-
Ethanol extract of magnolia officinalis prevents lipopolysaccharide-induced memory deficiency via its antineuroinflammatory and antiamyloidogenic effects
-
Lee, Y. J. et al. Ethanol Extract of Magnolia officinalis Prevents Lipopolysaccharide-Induced Memory Deficiency via Its Antineuroinflammatory and Antiamyloidogenic Effects. Phytotherapy Research 27, 438-447 (2013).
-
(2013)
Phytotherapy Research
, vol.27
, pp. 438-447
-
-
Lee, Y.J.1
-
47
-
-
33745096194
-
Inhibition of amyloid fibril formation by polyphenols: Structural similarity and aromatic interactions as a common inhibition mechanism
-
Porat, Y., Abramowitz, A. & Gazit, E. Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism. Chem Biol Drug Des 67, 27-37 (2006).
-
(2006)
Chem Biol Drug des
, vol.67
, pp. 27-37
-
-
Porat, Y.1
Abramowitz, A.2
Gazit, E.3
-
48
-
-
54049103538
-
Polyphenol-induced dissociation of various amyloid fibrils results in a methionine-independent formation of ros
-
Shoval, H. et al. Polyphenol-induced dissociation of various amyloid fibrils results in a methionine-independent formation of ROS. Biochim Biophys Acta 1784, 1570-7 (2008).
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 1570-1577
-
-
Shoval, H.1
-
49
-
-
77952346781
-
Egcg remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity
-
Bieschke, J. et al. EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity. Proc Natl Acad Sci USA 107, 7710-5 (2010).
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7710-7715
-
-
Bieschke, J.1
-
50
-
-
84858973650
-
Site specific interaction of the polyphenol egcg with the sevi amyloid precursor peptide pap(248-286)
-
Popovych, N. et al. Site specific interaction of the polyphenol EGCG with the SEVI amyloid precursor peptide PAP(248-286). J Phys Chem B 116, 3650-8 (2012).
-
(2012)
J Phys Chem B
, vol.116
, pp. 3650-3658
-
-
Popovych, N.1
-
51
-
-
84867488912
-
Alternative pathways of human islet amyloid polypeptide aggregation distinguished by (19)f nuclear magnetic resonance-detected kinetics of monomer consumption
-
Suzuki, Y., Brender, J. R., Hartman, K., Ramamoorthy, A. & Marsh, E. N. Alternative pathways of human islet amyloid polypeptide aggregation distinguished by (19)f nuclear magnetic resonance-detected kinetics of monomer consumption. Biochemistry 51, 8154-62 (2012).
-
(2012)
Biochemistry
, vol.51
, pp. 8154-8162
-
-
Suzuki, Y.1
Brender, J.R.2
Hartman, K.3
Ramamoorthy, A.4
Marsh, E.N.5
-
52
-
-
77956595088
-
The flavanol (?)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against iapp-induced toxicity
-
Meng, F., Abedini, A., Plesner, A., Verchere, C. B. & Raleigh, D. P. The flavanol (?)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity. Biochemistry 49, 8127-33 (2010).
-
(2010)
Biochemistry
, vol.49
, pp. 8127-8133
-
-
Meng, F.1
Abedini, A.2
Plesner, A.3
Verchere, C.B.4
Raleigh, D.P.5
-
53
-
-
84874609836
-
Insights into antiamyloidogenic properties of the green tea extract (?)-epigallocatechin-3-gallate toward metalassociated amyloid-beta species
-
Hyung, S. J. et al. Insights into antiamyloidogenic properties of the green tea extract (?)-epigallocatechin-3-gallate toward metalassociated amyloid-beta species. Proc Natl Acad Sci U S A 110, 3743-8 (2013).
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 3743-3748
-
-
Hyung, S.J.1
-
54
-
-
84858148877
-
Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease
-
Mecocci, P. & Polidori, M. C. Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease. Biochim Biophys Acta 1822, 631-8 (2012).
-
(2012)
Biochim Biophys Acta
, pp. 631-638
-
-
Mecocci, P.1
Polidori, M.C.2
-
55
-
-
84856492181
-
Nmr characterization of monomeric and oligomeric conformations of human calcitonin and its interaction with egcg
-
Huang, R. et al. NMR characterization of monomeric and oligomeric conformations of human calcitonin and its interaction with EGCG. J Mol Biol 416, 108-20 (2012).
-
(2012)
J Mol Biol
, vol.416
, pp. 108-120
-
-
Huang, R.1
-
56
-
-
84860446148
-
The contrasting effect of macromolecular crowding on amyloid fibril formation
-
Ma, Q. et al. The contrasting effect of macromolecular crowding on amyloid fibril formation. PLoS One 7, e36288 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e36288
-
-
Ma, Q.1
-
57
-
-
57649148788
-
Structural classification of toxic amyloid oligomers
-
Glabe, C. G. Structural classification of toxic amyloid oligomers. J Biol Chem 283, 29639-43 (2008).
-
(2008)
J Biol Chem
, vol.283
, pp. 29639-29643
-
-
Glabe, C.G.1
-
58
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed, R. et al. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-9 (2003).
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
-
59
-
-
36049009770
-
Binding of ferulic acid to cytochrome c enhances stability of the protein at physiological ph and inhibits cytochrome c-induced apoptosis
-
Yang, F. et al. Binding of ferulic acid to cytochrome c enhances stability of the protein at physiological pH and inhibits cytochrome c-induced apoptosis. Chem Biol Interact 170, 231-43 (2007).
-
(2007)
Chem Biol Interact
, vol.170
, pp. 231-243
-
-
Yang, F.1
-
60
-
-
0141567459
-
Physical stability of proteins in aqueous solution: Mechanism and driving forces in nonnative protein aggregation
-
Chi, E. Y., Krishnan, S., Randolph, T. W. & Carpenter, J. F. Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation. Pharm Res 20, 1325-36 (2003).
-
(2003)
Pharm Res
, vol.20
, pp. 1325-1336
-
-
Chi, E.Y.1
Krishnan, S.2
Randolph, T.W.3
Carpenter, J.F.4
-
61
-
-
61349145507
-
Development of tau aggregation inhibitors for Alzheimer's disease
-
Bulic, B. et al. Development of tau aggregation inhibitors for Alzheimer's disease. Angew Chem Int Ed Engl 48, 1740-52 (2009).
-
(2009)
Angew Chem Int Ed Engl
, vol.48
, pp. 1740-1752
-
-
Bulic, B.1
-
62
-
-
84894469764
-
Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease
-
Baptista, F. I., Henriques, A. G., Silva, A. M., Wiltfang, J. & da Cruz e Silva, O.A. Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease. ACS Chem Neurosci 5, 83-92 (2014).
-
(2014)
ACS Chem Neurosci
, vol.5
, pp. 83-92
-
-
Baptista, F.I.1
Henriques, A.G.2
Silva, A.M.3
Wiltfang, J.4
Da Cruze Silva, O.A.5
-
63
-
-
73149091019
-
A peptide hairpin inhibitor of amyloid beta-protein oligomerization and fibrillogenesis
-
Yamin, G., Ruchala, P. & Teplow, D. B. A peptide hairpin inhibitor of amyloid beta-protein oligomerization and fibrillogenesis. Biochemistry 48, 11329-31 (2009).
-
(2009)
Biochemistry
, vol.48
, pp. 11329-11331
-
-
Yamin, G.1
Ruchala, P.2
Teplow, D.B.3
-
64
-
-
78649757873
-
Inhibiting alpha-synuclein oligomerization by stable cell-penetrating beta-synuclein fragments recovers phenotype of Parkinson's disease model flies
-
Shaltiel-Karyo, R. et al. Inhibiting alpha-synuclein oligomerization by stable cell-penetrating beta-synuclein fragments recovers phenotype of Parkinson's disease model flies. PLoS One 5, e13863 (2010).
-
(2010)
PLoS One
, vol.5
, pp. e13863
-
-
Shaltiel-Karyo, R.1
-
65
-
-
33751249621
-
Phenol red interacts with the protobril-like oligomers of an amyloidogenic hexapeptide nfgail through both hydrophobic and aromatic contacts
-
Wu, C., Lei, H. X., Wang, Z. X., Zhang, W. & Duan, Y. Phenol red interacts with the protobril-like oligomers of an amyloidogenic hexapeptide NFGAIL through both hydrophobic and aromatic contacts. Biophysical Journal 91, 3664-3672 (2006).
-
(2006)
Biophysical Journal
, vol.91
, pp. 3664-3672
-
-
Wu, C.1
Lei, H.X.2
Wang, Z.X.3
Zhang, W.4
Duan, Y.5
-
66
-
-
79953837275
-
A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-Amyloidogenic agents for type-2 diabetes
-
Ahmad, E. et al. A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-Amyloidogenic agents for type-2 diabetes. Biochimie 93, 793-805 (2011).
-
(2011)
Biochimie
, vol.93
, pp. 793-805
-
-
Ahmad, E.1
-
67
-
-
84878090825
-
Role of aromatic residues in amyloid fibril formation of human calcitonin by solid-state 13c nmr and molecular dynamics simulation
-
Itoh-Watanabe, H. et al. Role of aromatic residues in amyloid fibril formation of human calcitonin by solid-state 13C NMR and molecular dynamics simulation. Phys Chem Chem Phys 15, 8890-901 (2013).
-
(2013)
Phys Chem Chem Phys
, vol.15
, pp. 8890-8901
-
-
Itoh-Watanabe, H.1
-
68
-
-
21244485899
-
Honokiol
-
Fullmer, M. J., Haltiwanger, R. C., Troupe, N. & Eggleston, D. S. Honokiol. Acta Crystallographica Section C 50, 1966-1967 (1994).
-
(1994)
Acta Crystallographica Section C
, vol.50
, pp. 1966-1967
-
-
Fullmer, M.J.1
Haltiwanger, R.C.2
Troupe, N.3
Eggleston, D.S.4
-
69
-
-
84987261105
-
Molecular and crystal structure of magnolol-c18h18o2
-
Wang, Y., Cheng, M.-C., Lee, J.-S. & Chen, F.-C. Molecular and Crystal Structure of Magnolol-C18H18O2. Journal of the Chinese Chemical Society 30, 215-221 (1983).
-
(1983)
Journal of the Chinese Chemical Society
, vol.30
, pp. 215-221
-
-
Wang, Y.1
Cheng, M.-C.2
Lee, J.-S.3
Chen, F.-C.4
-
70
-
-
84922782124
-
Amyloid form of ovalbumin evokes native antigen-specific immune response in the host: Prospective immunoprophylactic potential
-
Tufail, S. et al. Amyloid form of ovalbumin evokes native antigen-specific immune response in the host: prospective immunoprophylactic potential. J Biol Chem 290, 4131-48 (2015).
-
(2015)
J Biol Chem
, vol.290
, pp. 4131-4148
-
-
Tufail, S.1
-
71
-
-
70149116768
-
Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion nmr spectroscopy
-
Soong, R., Brender, J. R., Macdonald, P. M. & Ramamoorthy, A. Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy. J Am Chem Soc 131, 7079-85 (2009).
-
(2009)
J Am Chem Soc
, vol.131
, pp. 7079-7085
-
-
Soong, R.1
Brender, J.R.2
Macdonald, P.M.3
Ramamoorthy, A.4
-
72
-
-
84926643049
-
Self-Assembly of a nine-residue amyloid-forming peptide fragment of sars corona virus e-protein: Mechanism of self aggregation and amyloid-inhibition of hiapp
-
Ghosh, A. et al. Self-Assembly of a nine-residue amyloid-forming peptide fragment of SARS corona virus E-protein: mechanism of self aggregation and amyloid-inhibition of hIAPP. Biochemistry 54, 2249-61 (2015).
-
(2015)
Biochemistry
, vol.54
, pp. 2249-2261
-
-
Ghosh, A.1
-
73
-
-
67749097800
-
Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: The case of islet amyloid polypeptide
-
Smith, P. E., Brender, J. R. & Ramamoorthy, A. Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide. J Am Chem Soc 131, 4470-8 (2009).
-
(2009)
J Am Chem Soc
, vol.131
, pp. 4470-4478
-
-
Smith, P.E.1
Brender, J.R.2
Ramamoorthy, A.3
-
74
-
-
0035859102
-
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
-
Saborio, G. P., Permanne, B. & Soto, C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411, 810-3 (2001).
-
(2001)
Nature
, vol.411
, pp. 810-813
-
-
Saborio, G.P.1
Permanne, B.2
Soto, C.3
-
75
-
-
84899422309
-
Anti-Amyloid compounds inhibit alpha-synuclein aggregation induced by protein misfolding cyclic amplification (pmca)
-
Herva, M. E. et al. Anti-Amyloid compounds inhibit alpha-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA). J Biol Chem 289, 11897-905 (2014).
-
(2014)
J Biol Chem
, vol.289
, pp. 11897-11905
-
-
Herva, M.E.1
-
76
-
-
78650908339
-
Porcine islet amyloid polypeptide fragments are refractory to amyloid formation
-
Zhang, X. et al. Porcine islet amyloid polypeptide fragments are refractory to amyloid formation. FEBS Lett 585, 71-7 (2011).
-
(2011)
FEBS Lett
, vol.585
, pp. 71-77
-
-
Zhang, X.1
-
77
-
-
84904168587
-
Effects of several quinones on insulin aggregation
-
Gong, H. et al. Effects of several quinones on insulin aggregation. Sci Rep 4, 5648 (2014).
-
(2014)
Sci Rep
, vol.4
, pp. 5648
-
-
Gong, H.1
-
78
-
-
84872783464
-
Bisphenol a accelerates toxic amyloid formation of human islet amyloid polypeptide: A possible link between bisphenol a exposure and type 2 diabetes
-
Gong, H. et al. Bisphenol A accelerates toxic amyloid formation of human islet amyloid polypeptide: a possible link between bisphenol A exposure and type 2 diabetes. PLoS One 8, e54198 (2013).
-
(2013)
PLoS One
, vol.8
, pp. e54198
-
-
Gong, H.1
-
79
-
-
84862817939
-
Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide
-
Cheng, B. et al. Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide. Biochem Biophys Res Commun 419, 495-9 (2012).
-
(2012)
Biochem Biophys Res Commun
, vol.419
, pp. 495-499
-
-
Cheng, B.1
|