메뉴 건너뛰기




Volumn 19, Issue 1, 2014, Pages 1223-1237

Synthesis of tetrahydrohonokiol derivates and their evaluation for cytotoxic activity against ccrf-cem leukemia, u251 glioblastoma and hct-116 colon cancer cells

Author keywords

CCRF CEM leukemia cells; Cytotoxicity; HCT 116 colon cancer cells; Magnolia officinalis; Tetrahydrohonokiol derivatives; U251 glioblastoma

Indexed keywords

ANTINEOPLASTIC AGENT; BIPHENYL DERIVATIVE; HONOKIOL; LIGNAN;

EID: 84893091725     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19011223     Document Type: Article
Times cited : (16)

References (36)
  • 2
    • 84893044854 scopus 로고    scopus 로고
    • Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China; People's Medical Publishing House: Beijing, China, 2005
    • Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China; People's Medical Publishing House: Beijing, China, 2005.
  • 3
    • 0034035866 scopus 로고    scopus 로고
    • Overview of the pharmacological features of honokiol
    • Maruyama, Y.; Kuribara, H. Overview of the pharmacological features of honokiol. CNS Drug Rev. 2000, 6, 3-44.
    • (2000) CNS Drug Rev. , vol.6 , pp. 3-44
    • Maruyama, Y.1    Kuribara, H.2
  • 5
    • 66449098340 scopus 로고    scopus 로고
    • Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4-formation
    • Schühly, W.; Hüfner, A.; Pferschy-Wenzig, E.M.; Prettner, E.; Adams, M.; Bodensieck, A.; Kunert, O.; Oluwemimo, A.; Haslinger, E.; Bauer, R. Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase- mediated LTB4-formation. Bioorg. Med. Chem. 2009, 17, 4459-4465.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 4459-4465
    • Schühly, W.1    Hüfner, A.2    Pferschy-Wenzig, E.M.3    Prettner, E.4    Adams, M.5    Bodensieck, A.6    Kunert, O.7    Oluwemimo, A.8    Haslinger, E.9    Bauer, R.10
  • 7
    • 79961234552 scopus 로고    scopus 로고
    • Modulation of GABAA-Receptors by honokiol and derivatives: Subtype specificity and structure-Activity relationship
    • Taferner, B.; Schuehly, W.; Huefner, A.; Baburin, I.; Wiesner, K.; Ecker, G.F.; Hering, S. Modulation of GABAA-Receptors by Honokiol and Derivatives: Subtype Specificity and Structure-Activity Relationship. J. Med. Chem. 2011, 54, 5349-5361.
    • (2011) J. Med. Chem. , vol.54 , pp. 5349-5361
    • Taferner, B.1    Schuehly, W.2    Huefner, A.3    Baburin, I.4    Wiesner, K.5    Ecker, G.F.6    Hering, S.7
  • 10
    • 33644872086 scopus 로고    scopus 로고
    • Privileged structures as leads in medicinal chemistry
    • Costantino, L.; Barlocco, D. Privileged structures as leads in medicinal chemistry. Curr. Med. Chem. 2006, 13, 65-85.
    • (2006) Curr. Med. Chem. , vol.13 , pp. 65-85
    • Costantino, L.1    Barlocco, D.2
  • 12
    • 64749084915 scopus 로고    scopus 로고
    • Honokiol a multifunctional antiangiogenic and antitumor agent
    • Fried, L.E.; Arbiser, J.L. Honokiol, a multifunctional antiangiogenic and antitumor agent. Antioxid. Redox Signal. 2009, 11, 1139-1148.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 1139-1148
    • Fried, L.E.1    Arbiser, J.L.2
  • 14
    • 33749321904 scopus 로고    scopus 로고
    • Honokiol potentiates apoptosis, suppresses osteoclastogenesis and inhibits invasion through modulation of nuclear factor-?B activation pathway
    • Ahn, K.W.; Sethi, G.; Shishodia, S.; Sung, B.; Arbiser, J.L.; Aggarwal, B.B. Honokiol potentiates apoptosis, suppresses osteoclastogenesis and inhibits invasion through modulation of nuclear factor-?B activation pathway. Mol. Cancer Res. 2006, 4, 621-633.
    • (2006) Mol. Cancer Res. , vol.4 , pp. 621-633
    • Ahn, K.W.1    Sethi, G.2    Shishodia, S.3    Sung, B.4    Arbiser, J.L.5    Aggarwal, B.B.6
  • 16
    • 84859555338 scopus 로고    scopus 로고
    • Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway
    • Lin, J.-W.; Chen, J.-T.; Hong, C.-Y.; Lin, Y.-L.; Wang, K.-T.; Yao, C.-J.; Lai, G.-M.; Chen, R.-M. Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion- cytochrome c-caspase protease pathway. Neuro-Oncol. 2012, 14, 302-314.
    • (2012) Neuro-Oncol. , vol.14 , pp. 302-314
    • Lin, J.-W.1    Chen, J.-T.2    Hong, C.-Y.3    Lin, Y.-L.4    Wang, K.-T.5    Yao, C.-J.6    Lai, G.-M.7    Chen, R.-M.8
  • 17
    • 79955708703 scopus 로고    scopus 로고
    • Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral glioscarcoma model and human U251 xenograft glioma model
    • Wang, X.; Duan, X.; Yang, G.; Zhang, X.; Deng, L.; Zheng, H.; Deng, C.; Wen, J.; Wang, N.; Peng, C.; et al. Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral glioscarcoma model and human U251 xenograft glioma model. PloS One 2011, 6, e18490.
    • (2011) PloS One , vol.6
    • Wang, X.1    Duan, X.2    Yang, G.3    Zhang, X.4    Deng, L.5    Zheng, H.6    Deng, C.7    Wen, J.8    Wang, N.9    Peng, C.10
  • 21
    • 0036304314 scopus 로고    scopus 로고
    • Activity of drugs from traditional Chinese medicine toward sensitive and MDR1-or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells
    • Efferth, T.; Davey, M.; Olbrich, A.; Rücker, G.; Gebhart, E.; Davey, R. Activity of drugs from traditional Chinese medicine toward sensitive and MDR1-or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells. Blood Cell. Mol. Dis. 2002, 28, 160-168.
    • (2002) Blood Cell. Mol. Dis. , vol.28 , pp. 160-168
    • Efferth, T.1    Davey, M.2    Olbrich, A.3    Rücker, G.4    Gebhart, E.5    Davey, R.6
  • 22
    • 84860432055 scopus 로고
    • Honokiol a new phenolic compound isolated from the bark of magnolia obovata THUNB
    • Fujita, M.; Itokawa, H.; Sashida, Y. Honokiol, a New Phenolic Compound isolated from the Bark of Magnolia obovata THUNB. Chem. Pharm. Bull. 1972, 20, 212-213.
    • (1972) Chem. Pharm. Bull. , vol.20 , pp. 212-213
    • Fujita, M.1    Itokawa, H.2    Sashida, Y.3
  • 23
    • 0034809810 scopus 로고    scopus 로고
    • Enantiospecific synthesis of the proposed structure of the antitubercular marine diterpenoid pseudopteroxazole; revision of stereochemistry
    • Johnson, T.W.; Corey, E.J. Enantiospecific synthesis of the proposed structure of the antitubercular marine diterpenoid pseudopteroxazole; revision of stereochemistry. J. Am. Chem. Soc. 2001, 123, 4475-4479.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 4475-4479
    • Johnson, T.W.1    Corey, E.J.2
  • 26
    • 22144452194 scopus 로고    scopus 로고
    • The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells
    • Battle, T.E.; Arbiser, J.; Frank, D.A. The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells. Blood 2013, 106, 690-697.
    • (2013) Blood , vol.106 , pp. 690-697
    • Battle, T.E.1    Arbiser, J.2    Frank, D.A.3
  • 27
    • 84860460949 scopus 로고    scopus 로고
    • In vitro growth inhibition of human cancer cells by novel honokiol analogs
    • Lin, J.M.; Prakasha Gowda, A.S.; Sharma, A.K.; Amin, S. In vitro growth inhibition of human cancer cells by novel honokiol analogs. Bioorg. Med. Chem. 2012, 20, 3202-3211.
    • (2012) Bioorg. Med. Chem. , vol.20 , pp. 3202-3211
    • Lin, J.M.1    Prakasha Gowda, A.S.2    Sharma, A.K.3    Amin, S.4
  • 28
    • 84866524759 scopus 로고    scopus 로고
    • Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules
    • Jeong, J.J.; Lee, J.H.; Chang, K.C.; Kim, H.J. Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules. Int. J. Oncol. 2012, 41, 1358-1364.
    • (2012) Int. J. Oncol. , vol.41 , pp. 1358-1364
    • Jeong, J.J.1    Lee, J.H.2    Chang, K.C.3    Kim, H.J.4
  • 29
    • 84884476892 scopus 로고    scopus 로고
    • Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells
    • Chang, K.-H.; Yan, M.-D.; Yao, C.-J.; Lin, P.-C.; Lai, G.-M. Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells. Oncol. Lett. 2013, 6, 1435-1438
    • (2013) Oncol. Lett. , vol.6 , pp. 1435-1438
    • Chang, K.-H.1    Yan, M.-D.2    Yao, C.-J.3    Lin, P.-C.4    Lai, G.-M.5
  • 30
    • 80053917269 scopus 로고    scopus 로고
    • Structural modification of honokiol, a biphenyl occurring in Magnolia officinalis: The evaluation of honokiol analogues as inhibitors of angiogenesis and for their cytotoxicity and structure-Activity relationship
    • Ma, L.; Chen, J.; Wang, X.; Liang, X.; Luo, Y.; Zhu, W.; Wang, T.; Peng, M.; Li, S.; Jie, S.; et al. Structural modification of honokiol, a biphenyl occurring in Magnolia officinalis: The evaluation of honokiol analogues as inhibitors of angiogenesis and for their cytotoxicity and structure-Activity relationship. J. Med. Chem. 2011, 54, 6469-6481.
    • (2011) J. Med. Chem. , vol.54 , pp. 6469-6481
    • Ma, L.1    Chen, J.2    Wang, X.3    Liang, X.4    Luo, Y.5    Zhu, W.6    Wang, T.7    Peng, M.8    Li, S.9    Jie, S.10
  • 35
    • 0019978038 scopus 로고
    • Constituents of Magnolia grandiflora I: Mono-O-methylhonokiol
    • Rao, K.V.; Davis, T.L. Constituents of Magnolia grandiflora I: Mono-O-methylhonokiol. Planta Med. 1982, 45, 57-59.
    • (1982) Planta Med. , vol.45 , pp. 57-59
    • Rao, K.V.1    Davis, T.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.