Crocin and quercetin prevent PAT-induced apoptosis in mammalian cells: Involvement of ROS-mediated ER stress pathway

Environmental Toxicology

Volumn 31, Issue 12, 2016, Pages 1851-1858

  Boussabbeh, Manel ^a,b   Prola, Alexandre ^c   Ben Salem, Intidhar ^a,b   Guilbert, Arnaud ^c   Bacha, Hassen ^a   Lemaire, Christophe ^c,d,e   Abis Essefi, Salwa ^a  

^a Laboratory of Research on Biologically Compatible Compounds   (Tunisia)

^b UNIVERSITY OF CARTHAGE   (Tunisia)

^c INSERM   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

Author keywords

apoptosis; endoplasmic reticulum stress; oxidative stress; Patulin

Indexed keywords

CELL DEATH; CELL MEMBRANES; CHEMICAL ACTIVATION; FLAVONOIDS; FRUITS; MAMMALS; METABOLITES; MITOCHONDRIA; OXIDATIVE STRESS; PHENOLS; TOXICITY;

ANTIOXIDANT PROPERTIES; CASPASE-3 ACTIVATION; EMBRYONIC KIDNEY CELLS; ENDOPLASMIC RETICULUM STRESS; MITOCHONDRIAL MEMBRANE POTENTIAL; PATULIN; REACTIVE OXYGEN SPECIES; SECONDARY METABOLITES;

TOXIC MATERIALS;

CASPASE 3; CROCIN; GADD34 PROTEIN; GLUCOSE REGULATED PROTEIN 78; MALONALDEHYDE; PATULIN; PROTEIN; QUERCETIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ANTIOXIDANT; CAROTENOID; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; PHOSPHOPROTEIN PHOSPHATASE 1; PPP1R15A PROTEIN, HUMAN;

ANATOMY; ANTIOXIDANT; APOPTOSIS; CAROTENOID; CELLS AND CELL COMPONENTS; DRUG; ENZYME; FRUIT; FUNGUS; GENE EXPRESSION; MAMMAL; OXIDATION; OXIDATIVE STRESS; PROTEIN; REACTIVE OXYGEN SPECIES; SECONDARY METABOLITE; TOXIN;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; COLON CARCINOMA; EMBRYO; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; HCT116 CELL LINE; HEK293 CELL LINE; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; DNA FRAGMENTATION; DRUG EFFECTS; HCT 116 CELL LINE; METABOLISM;

ASPERGILLUS; BYSSOCHLAMYS; MALUS X DOMESTICA; MAMMALIA; PENICILLIUM;

ANTIOXIDANTS; APOPTOSIS; CAROTENOIDS; CASPASE 3; DNA FRAGMENTATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HCT116 CELLS; HEAT-SHOCK PROTEINS; HEK293 CELLS; HUMANS; LIPID PEROXIDATION; MALONDIALDEHYDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; PATULIN; PROTEIN PHOSPHATASE 1; QUERCETIN; REACTIVE OXYGEN SPECIES;

EID: 84940859352     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.22185     Document Type: Article

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