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Volumn 48, Issue 5, 2015, Pages 561-572

Ataxia-telangiectasia mutated (ATM) participates in the regulation of ionizing radiation-induced cell death via MAPK14 in lung cancer H1299 cells

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BECLIN 1; MITOGEN ACTIVATED PROTEIN KINASE 14; 2-MORPHOLIN-4-YL-6-THIANTHREN-1-YL-PYRAN-4-ONE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; MAP-KINASE-ACTIVATED KINASE 2; MEMBRANE PROTEIN; MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SERINE THREONINE KINASE; PYRONE DERIVATIVE; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE;

EID: 84940585626     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/cpr.12203     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 77951078783 scopus 로고    scopus 로고
    • Pattern of failure following chemoradiation for locally advanced non-small cell lung cancer: potential role for stereotactic body radiotherapy
    • Nguyen NP, Bishop M, Borok TJ, Welsh J, Hamilton R, Cohen D et al. (2010) Pattern of failure following chemoradiation for locally advanced non-small cell lung cancer: potential role for stereotactic body radiotherapy. Anticancer Res. 30, 953-961.
    • (2010) Anticancer Res. , vol.30 , pp. 953-961
    • Nguyen, N.P.1    Bishop, M.2    Borok, T.J.3    Welsh, J.4    Hamilton, R.5    Cohen, D.6
  • 3
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G (2008) Autophagy in the pathogenesis of disease. Cell 132, 27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 5
    • 79951580982 scopus 로고    scopus 로고
    • Chaperone-mediated autophagy: machinery, regulation and biological consequences
    • Li W, Yang Q, Mao Z (2011) Chaperone-mediated autophagy: machinery, regulation and biological consequences. Cell. Mol. Life Sci. 68, 749-763.
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 749-763
    • Li, W.1    Yang, Q.2    Mao, Z.3
  • 6
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer G, Marino G, Levine B (2010) Autophagy and the integrated stress response. Mol. Cell 40, 280-293.
    • (2010) Mol. Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 7
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: process and function
    • Mizushima N (2007) Autophagy: process and function. Genes Dev. 21, 2861-2873.
    • (2007) Genes Dev. , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 8
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: a double-edged sword
    • Shintani T, Klionsky DJ (2004) Autophagy in health and disease: a double-edged sword. Science 306, 990-995.
    • (2004) Science , vol.306 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 10
    • 84861526009 scopus 로고    scopus 로고
    • Deconvoluting the context-dependent role for autophagy in cancer
    • White E (2012) Deconvoluting the context-dependent role for autophagy in cancer. Nat. Rev. Cancer 12, 401-410.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 401-410
    • White, E.1
  • 12
    • 79956095420 scopus 로고    scopus 로고
    • Autophagosome formation and molecular mechanism of autophagy
    • Tanida I (2011) Autophagosome formation and molecular mechanism of autophagy. Antioxid. Redox Signal. 14, 2201-2214.
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 2201-2214
    • Tanida, I.1
  • 13
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V (2004) Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119, 753-766.
    • (2004) Cell , vol.119 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5    Deretic, V.6
  • 14
    • 0038309329 scopus 로고    scopus 로고
    • The molecular mechanism of autophagy
    • Wang CW, Klionsky DJ (2003) The molecular mechanism of autophagy. Mol. Med. 9, 65-76.
    • (2003) Mol. Med. , vol.9 , pp. 65-76
    • Wang, C.W.1    Klionsky, D.J.2
  • 15
    • 0036901639 scopus 로고    scopus 로고
    • Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366
    • Sapkota GP, Deak M, Kieloch A, Morrice N, Goodarzi AA, Smythe C et al. (2002) Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366. Biochem. J. 368, 507-516.
    • (2002) Biochem. J. , vol.368 , pp. 507-516
    • Sapkota, G.P.1    Deak, M.2    Kieloch, A.3    Morrice, N.4    Goodarzi, A.A.5    Smythe, C.6
  • 16
    • 79953236022 scopus 로고    scopus 로고
    • The role of LKB1 and AMPK in cellular responses to stress and damage
    • Alexander A, Walker CL (2011) The role of LKB1 and AMPK in cellular responses to stress and damage. FEBS Lett. 585, 952-957.
    • (2011) FEBS Lett. , vol.585 , pp. 952-957
    • Alexander, A.1    Walker, C.L.2
  • 18
    • 83755186557 scopus 로고    scopus 로고
    • Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer
    • Menendez JA, Cufi S, Oliveras-Ferraros C, Martin-Castillo B, Joven J, Vellon L et al. (2011) Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer. Aging (Albany NY) 3, 1063-1077.
    • (2011) Aging (Albany NY) , vol.3 , pp. 1063-1077
    • Menendez, J.A.1    Cufi, S.2    Oliveras-Ferraros, C.3    Martin-Castillo, B.4    Joven, J.5    Vellon, L.6
  • 19
    • 84857289515 scopus 로고    scopus 로고
    • Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress
    • Singh K, Matsuyama S, Drazba JA, Almasan A (2012) Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress. Autophagy 8, 236-251.
    • (2012) Autophagy , vol.8 , pp. 236-251
    • Singh, K.1    Matsuyama, S.2    Drazba, J.A.3    Almasan, A.4
  • 20
    • 79551473364 scopus 로고    scopus 로고
    • Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway
    • Chen LH, Loong CC, Su TL, Lee YJ, Chu PM, Tsai ML et al. (2011) Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway. Biochem. Pharmacol. 81, 594-605.
    • (2011) Biochem. Pharmacol. , vol.81 , pp. 594-605
    • Chen, L.H.1    Loong, C.C.2    Su, T.L.3    Lee, Y.J.4    Chu, P.M.5    Tsai, M.L.6
  • 21
    • 34249947699 scopus 로고    scopus 로고
    • ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
    • Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J et al. (2007) ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316, 1160-1166.
    • (2007) Science , vol.316 , pp. 1160-1166
    • Matsuoka, S.1    Ballif, B.A.2    Smogorzewska, A.3    McDonald, E.R.4    Hurov, K.E.5    Luo, J.6
  • 22
    • 67749117934 scopus 로고    scopus 로고
    • Signal integration by JNK and p38 MAPK pathways in cancer development
    • Wagner EF, Nebreda AR (2009) Signal integration by JNK and p38 MAPK pathways in cancer development. Nat. Rev. Cancer 9, 537-549.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 537-549
    • Wagner, E.F.1    Nebreda, A.R.2
  • 23
    • 43649105389 scopus 로고    scopus 로고
    • Signal-dependent regulation of gene expression as a target for cancer treatment: inhibiting p38alpha in colorectal tumors
    • Chiacchiera F, Simone C (2008) Signal-dependent regulation of gene expression as a target for cancer treatment: inhibiting p38alpha in colorectal tumors. Cancer Lett. 265, 16-26.
    • (2008) Cancer Lett. , vol.265 , pp. 16-26
    • Chiacchiera, F.1    Simone, C.2
  • 24
    • 77953506544 scopus 로고    scopus 로고
    • Regulation of autophagy by p38alpha MAPK
    • Webber JL (2010) Regulation of autophagy by p38alpha MAPK. Autophagy 6, 292-293.
    • (2010) Autophagy , vol.6 , pp. 292-293
    • Webber, J.L.1
  • 25
    • 69049096002 scopus 로고    scopus 로고
    • p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription
    • Chiacchiera F, Matrone A, Ferrari E, Ingravallo G, Lo Sasso G, Murzilli S et al. (2009) p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription. Cell Death Differ. 16, 1203-1214.
    • (2009) Cell Death Differ. , vol.16 , pp. 1203-1214
    • Chiacchiera, F.1    Matrone, A.2    Ferrari, E.3    Ingravallo, G.4    Lo Sasso, G.5    Murzilli, S.6
  • 26
    • 70349644002 scopus 로고    scopus 로고
    • Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism
    • Chiacchiera F, Simone C (2009) Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism. Autophagy 5, 1030-1033.
    • (2009) Autophagy , vol.5 , pp. 1030-1033
    • Chiacchiera, F.1    Simone, C.2
  • 27
    • 84864071314 scopus 로고    scopus 로고
    • Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models
    • Chiacchiera F, Grossi V, Cappellari M, Peserico A, Simonatto M, Germani A et al. (2012) Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models. Cancer Lett. 324, 98-108.
    • (2012) Cancer Lett. , vol.324 , pp. 98-108
    • Chiacchiera, F.1    Grossi, V.2    Cappellari, M.3    Peserico, A.4    Simonatto, M.5    Germani, A.6
  • 28
    • 84907169996 scopus 로고    scopus 로고
    • Elastase induces lung epithelial cell autophagy through placental growth factor: a new insight of emphysema pathogenesis
    • Hou HH, Cheng SL, Chung KP, Kuo MY, Yeh CC, Chang BE et al. (2014) Elastase induces lung epithelial cell autophagy through placental growth factor: a new insight of emphysema pathogenesis. Autophagy 10, 1509-1521.
    • (2014) Autophagy , vol.10 , pp. 1509-1521
    • Hou, H.H.1    Cheng, S.L.2    Chung, K.P.3    Kuo, M.Y.4    Yeh, C.C.5    Chang, B.E.6
  • 29
    • 84903833678 scopus 로고    scopus 로고
    • Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the transcription of autophagy genes in response to oxidative stress induced by a novel copper complex in HeLa cells
    • Zhong W, Zhu H, Sheng F, Tian Y, Zhou J, Chen Y et al. (2014) Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the transcription of autophagy genes in response to oxidative stress induced by a novel copper complex in HeLa cells. Autophagy 10, 1285-1300.
    • (2014) Autophagy , vol.10 , pp. 1285-1300
    • Zhong, W.1    Zhu, H.2    Sheng, F.3    Tian, Y.4    Zhou, J.5    Chen, Y.6
  • 30
    • 84866120470 scopus 로고    scopus 로고
    • MAPK14/p38alpha confers irinotecan resistance to TP53-defective cells by inducing survival autophagy
    • Paillas S, Causse A, Marzi L, de Medina P, Poirot M, Denis V et al. (2012) MAPK14/p38alpha confers irinotecan resistance to TP53-defective cells by inducing survival autophagy. Autophagy 8, 1098-1112.
    • (2012) Autophagy , vol.8 , pp. 1098-1112
    • Paillas, S.1    Causse, A.2    Marzi, L.3    de Medina, P.4    Poirot, M.5    Denis, V.6
  • 31
    • 84884322287 scopus 로고    scopus 로고
    • ATM pathway is essential for ionizing radiation-induced autophagy
    • Liang N, Jia L, Liu Y, Liang B, Kong D, Yan M et al. (2013) ATM pathway is essential for ionizing radiation-induced autophagy. Cell. Signal. 25, 2530-2539.
    • (2013) Cell. Signal. , vol.25 , pp. 2530-2539
    • Liang, N.1    Jia, L.2    Liu, Y.3    Liang, B.4    Kong, D.5    Yan, M.6
  • 32
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: their role in cell survival and cell death
    • Codogno P, Meijer AJ (2005) Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ. 12(Suppl 2), 1509-1518.
    • (2005) Cell Death Differ. , vol.12 , Issue.SUPPL 2 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 33
    • 77953699668 scopus 로고    scopus 로고
    • Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
    • Dalby KN, Tekedereli I, Lopez-Berestein G, Ozpolat B (2010) Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy 6, 322-329.
    • (2010) Autophagy , vol.6 , pp. 322-329
    • Dalby, K.N.1    Tekedereli, I.2    Lopez-Berestein, G.3    Ozpolat, B.4
  • 34
    • 84884812963 scopus 로고    scopus 로고
    • Targeting autophagy as a potential therapeutic approach for melanoma therapy
    • Liu H, He Z, Simon HU (2013) Targeting autophagy as a potential therapeutic approach for melanoma therapy. Semin. Cancer Biol. 23, 352-360.
    • (2013) Semin. Cancer Biol. , vol.23 , pp. 352-360
    • Liu, H.1    He, Z.2    Simon, H.U.3
  • 35
    • 84899493873 scopus 로고    scopus 로고
    • cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells
    • Cho EA, Kim EJ, Kwak SJ, Juhnn YS (2014) cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells. Mol. Cancer. 13, 36.
    • (2014) Mol. Cancer. , vol.13 , pp. 36
    • Cho, E.A.1    Kim, E.J.2    Kwak, S.J.3    Juhnn, Y.S.4
  • 36
    • 79251577061 scopus 로고    scopus 로고
    • The regulation of autophagy - unanswered questions
    • Chen Y, Klionsky DJ (2011) The regulation of autophagy - unanswered questions. J. Cell Sci. 124, 161-170.
    • (2011) J. Cell Sci. , vol.124 , pp. 161-170
    • Chen, Y.1    Klionsky, D.J.2
  • 38
    • 44349107112 scopus 로고    scopus 로고
    • Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways
    • Tang G, Yue Z, Talloczy Z, Hagemann T, Cho W, Messing A et al. (2008) Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways. Hum. Mol. Genet. 17, 1540-1555.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 1540-1555
    • Tang, G.1    Yue, Z.2    Talloczy, Z.3    Hagemann, T.4    Cho, W.5    Messing, A.6
  • 39
    • 80054862730 scopus 로고    scopus 로고
    • Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKalpha dependent manner
    • Luo Y, Zou P, Zou J, Wang J, Zhou D, Liu L (2011) Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKalpha dependent manner. Exp. Gerontol. 46, 860-867.
    • (2011) Exp. Gerontol. , vol.46 , pp. 860-867
    • Luo, Y.1    Zou, P.2    Zou, J.3    Wang, J.4    Zhou, D.5    Liu, L.6
  • 40
    • 75649085703 scopus 로고    scopus 로고
    • Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP
    • Webber JL, Tooze SA (2010) Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP. EMBO J. 29, 27-40.
    • (2010) EMBO J. , vol.29 , pp. 27-40
    • Webber, J.L.1    Tooze, S.A.2
  • 41
    • 33947418965 scopus 로고    scopus 로고
    • A novel cell type-specific role of p38alpha in the control of autophagy and cell death in colorectal cancer cells
    • Comes F, Matrone A, Lastella P, Nico B, Susca FC, Bagnulo R et al. (2007) A novel cell type-specific role of p38alpha in the control of autophagy and cell death in colorectal cancer cells. Cell Death Differ. 14, 693-702.
    • (2007) Cell Death Differ. , vol.14 , pp. 693-702
    • Comes, F.1    Matrone, A.2    Lastella, P.3    Nico, B.4    Susca, F.C.5    Bagnulo, R.6
  • 42
    • 84907164654 scopus 로고    scopus 로고
    • MAPK14/p38alpha-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation
    • Desideri E, Vegliante R, Cardaci S, Nepravishta R, Paci M, Ciriolo MR (2014) MAPK14/p38alpha-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation. Autophagy 10, 1652-1665.
    • (2014) Autophagy , vol.10 , pp. 1652-1665
    • Desideri, E.1    Vegliante, R.2    Cardaci, S.3    Nepravishta, R.4    Paci, M.5    Ciriolo, M.R.6
  • 43
    • 84866112397 scopus 로고    scopus 로고
    • Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition
    • Xie X, Le L, Fan Y, Lv L, Zhang J (2012) Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition. Autophagy 8, 1071-1084.
    • (2012) Autophagy , vol.8 , pp. 1071-1084
    • Xie, X.1    Le, L.2    Fan, Y.3    Lv, L.4    Zhang, J.5
  • 44
    • 84889686546 scopus 로고    scopus 로고
    • Autophagy activation by interferon-gamma via the p38 mitogen-activated protein kinase signalling pathway is involved in macrophage bactericidal activity
    • Matsuzawa T, Fujiwara E, Washi Y (2014) Autophagy activation by interferon-gamma via the p38 mitogen-activated protein kinase signalling pathway is involved in macrophage bactericidal activity. Immunology 141, 61-69.
    • (2014) Immunology , vol.141 , pp. 61-69
    • Matsuzawa, T.1    Fujiwara, E.2    Washi, Y.3
  • 45
    • 84867135263 scopus 로고    scopus 로고
    • Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway
    • Sun Y, Zou M, Hu C, Qin Y, Song X, Lu N et al. (2013) Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway. Food Chem. Toxicol. 51, 53-60.
    • (2013) Food Chem. Toxicol. , vol.51 , pp. 53-60
    • Sun, Y.1    Zou, M.2    Hu, C.3    Qin, Y.4    Song, X.5    Lu, N.6
  • 46
    • 84873852668 scopus 로고    scopus 로고
    • MicroRNA-18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells
    • Qased AB, Yi H, Liang N, Ma S, Qiao S, Liu X (2013) MicroRNA-18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells. Mol. Med. Rep. 7, 559-564.
    • (2013) Mol. Med. Rep. , vol.7 , pp. 559-564
    • Qased, A.B.1    Yi, H.2    Liang, N.3    Ma, S.4    Qiao, S.5    Liu, X.6
  • 47
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al. (2005) Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122, 927-939.
    • (2005) Cell , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Liang, X.H.5    Mizushima, N.6
  • 48
    • 63749131243 scopus 로고    scopus 로고
    • Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2
    • Reinhardt HC, Yaffe MB (2009) Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2. Curr. Opin. Cell Biol. 21, 245-255.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 245-255
    • Reinhardt, H.C.1    Yaffe, M.B.2
  • 50
    • 84896497591 scopus 로고    scopus 로고
    • ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells
    • Wang L, Yang H, Palmbos PL, Ney G, Detzler TA, Coleman D et al. (2014) ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells. Cancer Res. 74, 1778-1788.
    • (2014) Cancer Res. , vol.74 , pp. 1778-1788
    • Wang, L.1    Yang, H.2    Palmbos, P.L.3    Ney, G.4    Detzler, T.A.5    Coleman, D.6


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