Targeting molecular resistance in castration-resistant prostate cancer

BMC Medicine

Volumn 13, Issue 1, 2015, Pages

  Chandrasekar, Thenappan ^a   Yang, Joy C ^a   Gao, Allen C ^a   Evans, Christopher P ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE   (United States)

Author keywords

Castration resistant; Disease progression; Drug resistance; Prostatic neoplasms

Indexed keywords

ABIRATERONE ACETATE; ANDROGEN RECEPTOR ANTAGONIST; ANDROSTANOLONE; ANDROSTENEDIONE; APALUTAMIDE; APATORSEN; AZD 3514; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CABAZITAXEL; CLOMIPRAMINE; CUSTIRSEN; DOCETAXEL; ENZALUTAMIDE; EPI 001; GALETERONE; METFORMIN; MITOXANTRONE; NICLOSAMIDE; ODM 201; ORTERONEL; PLACEBO; PRASTERONE; PREDNISONE; PREGNENOLONE; UNCLASSIFIED DRUG; VT 464; ZOLEDRONIC ACID;

ABLATION THERAPY; ANDROGEN ABLATION THERAPY; APOPTOSIS; AUTOPHAGY; BINDING AFFINITY; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER RISK; CARBOXY TERMINAL SEQUENCE; CASTRATION RESISTANT PROSTATE CANCER; CROSS RESISTANCE; DEPOLYMERIZATION; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; HORMONAL THERAPY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MITOSIS; MOLECULAR BIOLOGY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); POINT MUTATION; PROGRESSION FREE SURVIVAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SECRETION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; STEROIDOGENESIS; TUMOR VOLUME; UPREGULATION; VISCERAL METASTASIS; DISEASE COURSE; GENETICS; MALE; PROSTATIC NEOPLASMS, CASTRATION-RESISTANT;

DISEASE PROGRESSION; HUMANS; MALE; PROSTATIC NEOPLASMS, CASTRATION-RESISTANT;

EID: 84940508576     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-015-0457-6     Document Type: Review

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