-
1
-
-
34247145969
-
Novel targets and approaches in advanced prostate cancer
-
Hadaschik BA, Sowery RD, Gleave ME. Novel targets and approaches in advanced prostate cancer. Curr Opin Urol 2007;17:182-7.
-
(2007)
Curr Opin Urol
, vol.17
, pp. 182-187
-
-
Hadaschik, B.A.1
Sowery, R.D.2
Gleave, M.E.3
-
2
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP, Tangen CM, Hussain MH, et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004;351:1513-20.
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
-
3
-
-
33644996125
-
Challenge and promise: Roles for clusterin in pathogenesis, progression and therapy of cancer
-
Shannan B, Seifert M, Leskov K, et al. Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer. Cell Death Differ 2006;13:12-9.
-
(2006)
Cell Death Differ
, vol.13
, pp. 12-19
-
-
Shannan, B.1
Seifert, M.2
Leskov, K.3
-
4
-
-
58349092086
-
Advances and challenges in basic and translational research on clusterin
-
Trougakos IP, Djeu JY, Gonos ES, Boothman DA. Advances and challenges in basic and translational research on clusterin. Cancer Res 2009;69:403-6.
-
(2009)
Cancer Res
, vol.69
, pp. 403-406
-
-
Trougakos, I.P.1
Djeu, J.Y.2
Gonos, E.S.3
Boothman, D.A.4
-
5
-
-
26944445883
-
Clusterin inhibits apoptosis by interacting with activated Bax
-
DOI 10.1038/ncb1291, PII N1291
-
Zhang H, Kim JK, Edwards CA, Xu Z, Taichman R, Wang CY. Clusterin inhibits apoptosis by interacting with activated Bax. Nat Cell Biol 2005;7:909-15. (Pubitemid 41486292)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.9
, pp. 909-915
-
-
Zhang, H.1
Kim, J.K.2
Edwards, C.A.3
Xu, Z.4
Taichman, R.5
Wang, C.-Y.6
-
6
-
-
34247387196
-
Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol
-
Nizard P, Tetley S, Le Drean Y, et al. Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol. Traffic 2007;8:554-65.
-
(2007)
Traffic
, vol.8
, pp. 554-565
-
-
Nizard, P.1
Tetley, S.2
Le Drean, Y.3
-
7
-
-
58849123363
-
Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex
-
Trougakos IP, Lourda M, Antonelou MH, et al. Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex. Clin Cancer Res 2009;15:48-59.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 48-59
-
-
Trougakos, I.P.1
Lourda, M.2
Antonelou, M.H.3
-
8
-
-
33748929660
-
Expression of clusterin in prostate cancer correlates with Gleason score but not with prognosis in patients undergoing radical prostatectomy without neoadjuvant hormonal therapy
-
Miyake H, Muramaki M, Kurahashi T, et al. Expression of clusterin in prostate cancer correlates with Gleason score but not with prognosis in patients undergoing radical prostatectomy without neoadjuvant hormonal therapy. Urology 2006;68:609-14.
-
(2006)
Urology
, vol.68
, pp. 609-614
-
-
Miyake, H.1
Muramaki, M.2
Kurahashi, T.3
-
9
-
-
0030843011
-
Intracellular levels of SGP-2 (Clusterin) correlate with tumor grade in prostate cancer
-
Steinberg J, Oyasu R, Lang S, et al. Intracellular levels of SGP-2 (clusterin) correlate with tumor grade in prostate cancer. Clin Cancer Res 1997;3:1707-11. (Pubitemid 27444708)
-
(1997)
Clinical Cancer Research
, vol.3
, Issue.10
, pp. 1707-1711
-
-
Steinberg, J.1
Oyasu, R.2
Lang, S.3
Sintich, S.4
Rademaker, A.5
Lee, C.6
Kozlowski, J.M.7
Sensibar, J.A.8
-
10
-
-
0028366242
-
Gp80 (clusterin; TRPM-2) mRNA level is enhanced in human renal clear cell carcinomas
-
DOI 10.1007/BF01202200
-
Parczyk K, Pilarsky C, Rachel U, Koch-Brandt C. Gp80 (clusterin; TRPM-2) mRNA level is enhanced in human renal clear cell carcinomas. J Cancer Res Clin Oncol 1994;120:186-8. (Pubitemid 23337946)
-
(1994)
Journal of Cancer Research and Clinical Oncology
, vol.120
, Issue.3
, pp. 186-188
-
-
Parczyk, K.1
Pilarsky, C.2
Rachel, U.3
Koch-Brandt, C.4
-
11
-
-
0033903190
-
Overexpression of clusterin in human breast carcinoma
-
Redondo M, Villar E, Torres-Munoz J, Tellez T, Morell M, Petito CK. Overexpression of clusterin in human breast carcinoma. Am J Pathol 2000;157:393-9. (Pubitemid 30626904)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.2
, pp. 393-399
-
-
Redondo, M.1
Villar, E.2
Torres-Munoz, J.3
Tellez, T.4
Morell, M.5
Petito, C.K.6
-
12
-
-
30344481694
-
Knockdown of the cytoprotective chaperone, clusterin, chemosensitizes human breast cancer cells both in vitro and in vivo
-
DOI 10.1158/1535-7163.MCT-05-0178
-
So A, Sinnemann S, Huntsman D, Fazli L, Gleave M. Knockdown of the cytoprotective chaperone, clusterin, chemosensitizes human breast cancer cells both in vitro and in vivo. Mol Cancer Ther 2005;4:1837-49. (Pubitemid 43056967)
-
(2005)
Molecular Cancer Therapeutics
, vol.4
, Issue.12
, pp. 1837-1849
-
-
So, A.1
Sinnemann, S.2
Huntsman, D.3
Fazli, L.4
Gleave, M.E.5
-
13
-
-
12344322308
-
Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma
-
DOI 10.1002/cncr.20765
-
Xie D, Lau SH, Sham JS, et al. Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma. Cancer 2005;103:277-83. (Pubitemid 40129286)
-
(2005)
Cancer
, vol.103
, Issue.2
, pp. 277-283
-
-
Xie, D.1
Sze, H.L.2
Sham, J.S.T.3
Wu, Q.-L.4
Fang, Y.5
Liang, L.-Z.6
Che, L.-H.7
Zeng, Y.-X.8
Guan, X.-Y.9
-
14
-
-
1842589298
-
Modulation of different clusterin isoforms in human colon tumorigenesis
-
DOI 10.1038/sj.onc.1207404
-
Pucci S, Bonanno E, Pichiorri F, Angeloni C, Spagnoli LG. Modulation of different clusterin isoforms in human colon tumorigenesis. Oncogene 2004;23:2298-304. (Pubitemid 38496784)
-
(2004)
Oncogene
, vol.23
, Issue.13
, pp. 2298-2304
-
-
Pucci, S.1
Bonanno, E.2
Pichiorri, F.3
Angeloni, C.4
Spagnoli, L.G.5
-
15
-
-
4444222462
-
Nucleotide-based therapies targeting clusterin chemosensitize human lung adenocarcinoma cells both in vitro and in vivo
-
July LV, Beraldi E, So A, et al. Nucleotide-based therapies targeting clusterin chemosensitize human lung adenocarcinoma cells both in vitro and in vivo. Mol Cancer Ther 2004;3:223-32. (Pubitemid 39193697)
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.3
, pp. 223-232
-
-
July, L.V.1
Beraldi, E.2
So, A.3
Fazli, L.4
Evans, K.5
English, J.C.6
Gleave, M.E.7
-
16
-
-
33846504040
-
Clusterin is highly expressed in pancreatic endocrine tumours but not in solid pseudopapillary tumours
-
DOI 10.1111/j.1365-2559.2007.02608.x
-
Mourra N, Couvelard A, Tiret E, Olschwang S, Flejou JF. Clusterin is highly expressed in pancreatic endocrine tumours but not in solid pseudopapillary tumours. Histopathology 2007;50:331-7. (Pubitemid 46169417)
-
(2007)
Histopathology
, vol.50
, Issue.3
, pp. 331-337
-
-
Mourra, N.1
Couvelard, A.2
Tiret, E.3
Olschwang, S.4
Flejou, J.-F.5
-
17
-
-
39249084676
-
Clusterin expression predicts survival of invasive cervical cancer patients treated with radical hysterectomy and systematic lymphadenectomy
-
Watari H, Ohta Y, Hassan MK, Xiong Y, Tanaka S, Sakuragi N. Clusterin expression predicts survival of invasive cervical cancer patients treated with radical hysterectomy and systematic lymphadenectomy. Gynecol Oncol 2008;108:527-32.
-
(2008)
Gynecol Oncol
, vol.108
, pp. 527-532
-
-
Watari, H.1
Ohta, Y.2
Hassan, M.K.3
Xiong, Y.4
Tanaka, S.5
Sakuragi, N.6
-
18
-
-
20144362454
-
Clusterin regulates drug-resistance in melanoma cells
-
DOI 10.1111/j.0022-202X.2005.23720.x
-
Hoeller C, Pratscher B, Thallinger C, et al. Clusterin regulates drug-resistance in melanoma cells. J Invest Dermatol 2005;124:1300-7. (Pubitemid 40847419)
-
(2005)
Journal of Investigative Dermatology
, vol.124
, Issue.6
, pp. 1300-1307
-
-
Hoeller, C.1
Pratscher, B.2
Thallinger, C.3
Winter, D.4
Fink, D.5
Kovacic, B.6
Sexl, V.7
Wacheck, V.8
Gleave, M.E.9
Pehamberger, H.10
Jansen, B.11
-
19
-
-
0026051782
-
Human gliomas and epileptic foci express high levels of a mRNA related to rat testicular sulfated glycoprotein 2, a purported marker of cell death
-
Danik M, Chabot JG, Mercier C, et al. Human gliomas and epileptic foci express high levels of a mRNA related to rat testicular sulfated glycoprotein 2, a purported marker of cell death. Proc Natl Acad Sci U S A 1991;88:8577-81. (Pubitemid 21915400)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.19
, pp. 8577-8581
-
-
Danik, M.1
Chabot, J.-G.2
Mercier, C.3
Benabid, A.-L.4
Chauvin, C.5
Quirion, R.6
Suh, M.7
-
20
-
-
0034661519
-
Detection of differentially expressed genes in lymphomas using cDNA arrays: Identification of clusterin as a new diagnostic marker for anaplastic large-cell lymphomas
-
Wellmann A, Thieblemont C, Pittaluga S, et al. Detection of differentially expressed genes in lymphomas using cDNA arrays: identification of clusterin as a new diagnostic marker for anaplastic large-cell lymphomas. Blood 2000;96:398-404.
-
(2000)
Blood
, vol.96
, pp. 398-404
-
-
Wellmann, A.1
Thieblemont, C.2
Pittaluga, S.3
-
21
-
-
0034192382
-
Acquisition of chemoresistant phenotype by overexpression of the antiapoptotic gene testosterone-repressed prostate message-2 in prostate cancer xenograft models
-
Miyake H, Nelson C, Rennie PS, Gleave ME. Acquisition of chemoresistant phenotype by overexpression of the antiapoptotic gene testosterone-repressed prostate message-2 in prostate cancer xenograft models. Cancer Res 2000;60:2547-54.
-
(2000)
Cancer Res
, vol.60
, pp. 2547-2554
-
-
Miyake, H.1
Nelson, C.2
Rennie, P.S.3
Gleave, M.E.4
-
22
-
-
0033978525
-
Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer
-
Miyake H, Nelson C, Rennie PS, Gleave ME. Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer. Cancer Res 2000;60:170-6.
-
(2000)
Cancer Res
, vol.60
, pp. 170-176
-
-
Miyake, H.1
Nelson, C.2
Rennie, P.S.3
Gleave, M.E.4
-
23
-
-
0036796026
-
Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin
-
Zellweger T, Chi K, Miyake H, et al. Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin. Clin Cancer Res 2002;8:3276-84.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3276-3284
-
-
Zellweger, T.1
Chi, K.2
Miyake, H.3
-
24
-
-
33749825228
-
Novel role of Stat1 in the development of docetaxel resistance in prostate tumor cells
-
Patterson SG, Wei S, Chen X, et al. Novel role of Stat1 in the development of docetaxel resistance in prostate tumor cells. Oncogene 2006;25:6113-22.
-
(2006)
Oncogene
, vol.25
, pp. 6113-6122
-
-
Patterson, S.G.1
Wei, S.2
Chen, X.3
-
25
-
-
47649133156
-
Clusterin knockdown using the antisense oligonucleotide OGX-011 re-sensitizes docetaxel-refractory prostate cancer PC-3 cells to chemotherapy
-
Sowery RD, Hadaschik BA, So AI, et al. Clusterin knockdown using the antisense oligonucleotide OGX-011 re-sensitizes docetaxel-refractory prostate cancer PC-3 cells to chemotherapy. BJU Int 2008;102:389-97.
-
(2008)
BJU Int
, vol.102
, pp. 389-397
-
-
Sowery, R.D.1
Hadaschik, B.A.2
So, A.I.3
-
26
-
-
36749021164
-
Clusterin mediates TRAIL resistance in prostate tumor cells
-
Sallman DA, Chen X, Zhong B, et al. Clusterin mediates TRAIL resistance in prostate tumor cells. Mol Cancer Ther 2007;6:2938-47.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2938-2947
-
-
Sallman, D.A.1
Chen, X.2
Zhong, B.3
-
27
-
-
0036753752
-
Suppression of clusterin expression enhanced cisplatin-induced cytotoxicity on renal cell carcinoma cells
-
Lee CH, Jin RJ, Kwak C, et al. Suppression of clusterin expression enhanced cisplatin-induced cytotoxicity on renal cell carcinoma cells. Urology 2002;60:516-20.
-
(2002)
Urology
, vol.60
, pp. 516-520
-
-
Lee, Ch.1
Jin, R.J.2
Kwak, C.3
-
28
-
-
33845713308
-
Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of Clusterin/Apolipoprotein J
-
DOI 10.1002/ijc.22327
-
Lourda M, Trougakos IP, Gonos ES. Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of clusterin/apolipoprotein J. Int J Cancer 2007;120:611-22. (Pubitemid 44969033)
-
(2007)
International Journal of Cancer
, vol.120
, Issue.3
, pp. 611-622
-
-
Lourda, M.1
Trougakos, I.P.2
Gonos, E.S.3
-
29
-
-
0035675829
-
Synergistic chemsensitization and inhibition of tumor growth and metastasis by the antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model
-
Miyake H, Hara I, Kamidono S, Gleave ME. Synergistic chemosensitization and inhibition of tumor growth and metastasis by the antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model. Clin Cancer Res 2001;7:4245-52. (Pubitemid 34044651)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.12
, pp. 4245-4252
-
-
Miyake, H.1
Hara, I.2
Kamidono, S.3
Gleave, M.E.4
-
30
-
-
67650095405
-
Roles of clusterin in progression chemoresistance and metastasis of human ovarian cancer
-
Wei L, Xue T, Wang J, et al. Roles of clusterin in progression, chemoresistance and metastasis of human ovarian cancer. Int J Cancer 2009;125:791-806.
-
(2009)
Int J Cancer
, vol.125
, pp. 791-806
-
-
Wei, L.1
Xue, T.2
Wang, J.3
-
31
-
-
0242525635
-
Gene Amplifications Associated with the Development of Hormone-Resistant Prostate Cancer
-
Edwards J, Krishna NS, Witton CJ, Bartlett JM. Gene amplifications associated with the development of hormone-resistant prostate cancer. Clin Cancer Res 2003;9:5271-81. (Pubitemid 37413579)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.14
, pp. 5271-5281
-
-
Edwards, J.1
Krishna, N.S.2
Witton, C.J.3
Bartlett, J.M.S.4
-
32
-
-
3042743988
-
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt
-
Yang L, Dan HC, Sun M, et al. Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res 2004;64:4394-9.
-
(2004)
Cancer Res
, vol.64
, pp. 4394-4399
-
-
Yang, L.1
Dan, H.C.2
Sun, M.3
-
33
-
-
0038342509
-
AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: Implication of AKT2 in chemoresistance
-
Yuan ZQ, Feldman RI, Sussman GE, Coppola D, Nicosia SV, Cheng JQ. AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. J Biol Chem 2003;278:23432-40.
-
(2003)
J Biol Chem
, vol.278
, pp. 23432-23440
-
-
Yuan, Z.Q.1
Feldman, R.I.2
Sussman, G.E.3
Coppola, D.4
Nicosia, S.V.5
Cheng, J.Q.6
-
34
-
-
0032771030
-
A newhuman prostate carcinoma cell line, 22Rv1
-
Sramkoski RM, PretlowTG II, Giaconia JM, et al.A newhuman prostate carcinoma cell line, 22Rv1. In Vitro Cell Dev Biol Anim 1999;35:403-9.
-
(1999)
In Vitro Cell Dev Biol Anim
, vol.35
, pp. 403-409
-
-
Sramkoski, R.M.1
Pretlow II, T.G.2
Giaconia, J.M.3
-
35
-
-
13844266738
-
Differential effects of clusterin/apolipoprotein J on cellular growth and survival
-
Trougakos IP, Lourda M, Agiostratidou G, Kletsas D, Gonos ES. Differential effects of clusterin/apolipoprotein J on cellular growth and survival. Free Radic Biol Med 2005;38:436-49.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 436-449
-
-
Trougakos, I.P.1
Lourda, M.2
Agiostratidou, G.3
Kletsas, D.4
Gonos, E.S.5
-
36
-
-
0032126505
-
Frequent inactivation of PTEN in prostate cancer cell lines and xenografts
-
Vlietstra RJ, van Alewijk DC, Hermans KG, van Steenbrugge GJ, Trapman J. Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Res 1998;58:2720-3.
-
(1998)
Cancer Res
, vol.58
, pp. 2720-2723
-
-
Vlietstra, R.J.1
Van Alewijk, D.C.2
Hermans, K.G.3
Van Steenbrugge, G.J.4
Trapman, J.5
-
37
-
-
10844235652
-
Androgen-independent prostate cancer is a heterogeneous group of diseases: Lessons from a rapid autopsy program
-
Shah RB, Mehra R, Chinnaiyan AM, et al. Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program. Cancer Res 2004;64:9209-16.
-
(2004)
Cancer Res
, vol.64
, pp. 9209-9216
-
-
Shah, R.B.1
Mehra, R.2
Chinnaiyan, A.M.3
-
38
-
-
1642282641
-
Silencing expression of the clusterin/apolipoprotein J gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress
-
Trougakos IP, So A, Jansen B, Gleave ME, Gonos ES. Silencing expression of the clusterin/apolipoprotein J gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress. Cancer Res 2004;64:1834-42.
-
(2004)
Cancer Res
, vol.64
, pp. 1834-1842
-
-
Trougakos, I.P.1
So, A.2
Jansen, B.3
Gleave, M.E.4
Gonos, E.S.5
-
39
-
-
0031035693
-
Bcl2 is the guardian of microtubule integrity
-
Haldar S, Basu A, Croce CM. Bcl2 is the guardian of microtubule integrity. Cancer Res 1997;57:229-33.
-
(1997)
Cancer Res
, vol.57
, pp. 229-233
-
-
Haldar, S.1
Basu, A.2
Croce, C.M.3
-
40
-
-
0032514914
-
Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest
-
Scatena CD, Stewart ZA, Mays D, et al. Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest. J Biol Chem 1998;273:30777-84.
-
(1998)
J Biol Chem
, vol.273
, pp. 30777-30784
-
-
Scatena, C.D.1
Stewart, Z.A.2
Mays, D.3
-
41
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, de Wit R, Berry WR, et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004;351:1502-12.
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
De Wit, R.2
Berry, W.R.3
-
42
-
-
33750958133
-
Expression of clusterin, XIAP and survivin, and their changes by camptothecin (CPT) treatment in CPT-resistant PC-3 and CPT-sensitive LNCaP cells
-
Mizutani K, Matsumoto K, Hasegawa N, Deguchi T, Nozawa Y. Expression of clusterin, XIAP and survivin, and their changes by camptothecin (CPT) treatment in CPT-resistant PC-3 and CPT-sensitive LNCaP cells. Exp Oncol 2006;28:209-15.
-
(2006)
Exp Oncol
, vol.28
, pp. 209-215
-
-
Mizutani, K.1
Matsumoto, K.2
Hasegawa, N.3
Deguchi, T.4
Nozawa, Y.5
-
43
-
-
0035823494
-
Roles of phosphatidylinositol 3-kinase in interferon-γ-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression
-
Nguyen H, Ramana CV, Bayes J, Stark GR. Roles of phosphatidylinositol 3-kinase in interferon-γ-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression. J Biol Chem 2001;276:33361-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 33361-33368
-
-
Nguyen, H.1
Ramana, C.V.2
Bayes, J.3
Stark, G.R.4
-
44
-
-
33947192053
-
Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
-
Cheng GZ, Chan J, Wang Q, Zhang W, Sun CD, Wang LH. Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res 2007;67:1979-87.
-
(2007)
Cancer Res
, vol.67
, pp. 1979-1987
-
-
Cheng, G.Z.1
Chan, J.2
Wang, Q.3
Zhang, W.4
Sun, C.D.5
Wang, L.H.6
-
45
-
-
0035815649
-
Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis
-
Nesterov A, Lu X, Johnson M, Miller GJ, Ivashchenko Y, Kraft AS. Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis. J Biol Chem 2001;276:10767-74.
-
(2001)
J Biol Chem
, vol.276
, pp. 10767-10774
-
-
Nesterov, A.1
Lu, X.2
Johnson, M.3
Miller, G.J.4
Ivashchenko, Y.5
Kraft, A.S.6
-
46
-
-
45149104050
-
Clusterin activates survival through the phosphatidylinositol 3-kinase/Akt pathway
-
Ammar H, Closset JL. Clusterin activates survival through the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem 2008;283:12851-61.
-
(2008)
J Biol Chem
, vol.283
, pp. 12851-12861
-
-
Ammar, H.1
Closset, J.L.2
-
47
-
-
0029061350
-
Prevention of cell death induced by tumor necrosis factor α in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin)
-
Sensibar JA, Sutkowski DM, Raffo A, et al. Prevention of cell death induced by tumor necrosis factor α in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin). Cancer Res 1995;55:2431-7.
-
(1995)
Cancer Res
, vol.55
, pp. 2431-2437
-
-
Sensibar, J.A.1
Sutkowski, D.M.2
Raffo, A.3
-
48
-
-
0034856692
-
Acquisition of resistance to Fas-mediated apoptosis by overexpression of clusterin in human renal-cell carcinoma cells
-
Miyake H, Hara S, Zellweger T, Kamidono S, Gleave ME, Hara I. Acquisition of resistance to Fas-mediated apoptosis by overexpression of clusterin in human renal-cell carcinoma cells. Mol Urol 2001;5:105-11.
-
(2001)
Mol Urol
, vol.5
, pp. 105-111
-
-
Miyake, H.1
Hara, S.2
Zellweger, T.3
Kamidono, S.4
Gleave, M.E.5
Hara, I.6
-
49
-
-
0034705103
-
Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death
-
Yang CR, Leskov K, Hosley-Eberlein K, et al. Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death. Proc Natl Acad Sci U S A 2000;97:5907-12.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5907-5912
-
-
Yang, C.R.1
Leskov, K.2
Hosley-Eberlein, K.3
-
50
-
-
0142227019
-
Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
-
Luo J, Manning BD, Cantley LC. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 2003;4:257-62.
-
(2003)
Cancer Cell
, vol.4
, pp. 257-262
-
-
Luo, J.1
Manning, B.D.2
Cantley, L.C.3
-
51
-
-
38949099997
-
The AKT inhibitor perifosine in biochemically recurrent prostate cancer: A phase II California/Pittsburgh cancer consortium trial
-
Chee KG, Longmate J, Quinn DI, et al. The AKT inhibitor perifosine in biochemically recurrent prostate cancer: a phase II California/Pittsburgh cancer consortium trial. Clin Genitourin Cancer 2007;5:433-7.
-
(2007)
Clin Genitourin Cancer
, vol.5
, pp. 433-437
-
-
Chee, K.G.1
Longmate, J.2
Quinn, D.I.3
-
52
-
-
38949153810
-
A phase I study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer
-
Chi KN, Siu LL, Hirte H, et al. A phase I study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer. Clin Cancer Res 2008;14:833-9.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 833-839
-
-
Chi, K.N.1
Siu, L.L.2
Hirte, H.3
|