Possible role of adaptive mutation in resistance to antiandrogen in prostate cancer cells

Prostate

Volumn 65, Issue 3, 2005, Pages 268-275

  Hara, Takahito ^a   Kouno, Jin ^a   Nakamura, Kazuyo ^a   Kusaka, Masami ^a   Yamaoka, Masuo ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Adaptive mutation; Androgen receptor; Antiandrogen; Hypermutation; Prostate cancer

Indexed keywords

AMINO ACID; ANDROGEN; ANDROGEN RECEPTOR; ANTIANDROGEN; BICALUTAMIDE; CYSTEINE; DNA MISMATCH REPAIR PROTEIN; DNA POLYMERASE; LEUCINE; NUCLEIC ACID BINDING PROTEIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ADAPTATION; AMINO ACID SEQUENCE; ARTICLE; CANCER CELL CULTURE; CULTURE MEDIUM; DOWN REGULATION; DRUG RESISTANCE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE CANCER; SEQUENCE ANALYSIS;

ANDROGEN ANTAGONISTS; ANILIDES; BASE SEQUENCE; BLOTTING, WESTERN; CELL CYCLE; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DNA-DIRECTED DNA POLYMERASE; DRUG RESISTANCE, NEOPLASM; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASMS, HORMONE-DEPENDENT; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM;

EID: 26644444330     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.20282     Document Type: Article

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