-
1
-
-
84903684771
-
Molecular targeted therapy in lung cancer
-
Fujioka N, Bitterman PB. Molecular targeted therapy in lung cancer. Minn Med. 2012; 95:38-41.
-
(2012)
Minn Med
, vol.95
, pp. 38-41
-
-
Fujioka, N.1
Bitterman, P.B.2
-
2
-
-
84865342131
-
Non-small cell lung cancer: from targeted therapy to tailored therapy
-
Malgieri S, Feliciano S, Bosso D, Federico P, Palmieri G, De Placido S, Di Lorenzo G, Buonerba C. Non-small cell lung cancer: from targeted therapy to tailored therapy. Expert Opin Pharmacother. 2012; 13:1817-1819.
-
(2012)
Expert Opin Pharmacother
, vol.13
, pp. 1817-1819
-
-
Malgieri, S.1
Feliciano, S.2
Bosso, D.3
Federico, P.4
Palmieri, G.5
De Placido, S.6
Di Lorenzo, G.7
Buonerba, C.8
-
4
-
-
84866940771
-
Personalized targeted therapy for lung cancer
-
Wu K, House L, Liu W, Cho WC. Personalized targeted therapy for lung cancer. Int J Mol Sci. 2012; 13:11471-11496.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 11471-11496
-
-
Wu, K.1
House, L.2
Liu, W.3
Cho, W.C.4
-
5
-
-
27844511101
-
Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
-
Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005; 45:1345-1359.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 1345-1359
-
-
Zhou, L.1
Zuo, Z.2
Chow, M.S.3
-
6
-
-
40749148985
-
Pharmacokinetic characterization of hydroxylpropyl-beta-cyclodextrin-included complex of cryptotanshinone, an investigational cardiovascular drug purified from Danshen (Salvia miltiorrhiza)
-
Pan Y, Bi HC, Zhong GP, Chen X, Zuo Z, Zhao LZ, Gu LQ, Liu PQ, Huang ZY, Zhou SF, Huang M. Pharmacokinetic characterization of hydroxylpropyl-beta-cyclodextrin-included complex of cryptotanshinone, an investigational cardiovascular drug purified from Danshen (Salvia miltiorrhiza). Xenobiotica. 2008; 38:382-398.
-
(2008)
Xenobiotica
, vol.38
, pp. 382-398
-
-
Pan, Y.1
Bi, H.C.2
Zhong, G.P.3
Chen, X.4
Zuo, Z.5
Zhao, L.Z.6
Gu, L.Q.7
Liu, P.Q.8
Huang, Z.Y.9
Zhou, S.F.10
Huang, M.11
-
7
-
-
77955452597
-
Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation
-
Chen W, Luo Y, Liu L, Zhou H, Xu B, Han X, Shen T, Liu Z, Lu Y, Huang S. Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation. Cancer Prev Res (Phila). 2010; 3:1015-1025.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1015-1025
-
-
Chen, W.1
Luo, Y.2
Liu, L.3
Zhou, H.4
Xu, B.5
Han, X.6
Shen, T.7
Liu, Z.8
Lu, Y.9
Huang, S.10
-
8
-
-
77956671604
-
Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression
-
Cheng CY, Su CC. Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression. Int J Mol Med. 2010; 26:379-385.
-
(2010)
Int J Mol Med
, vol.26
, pp. 379-385
-
-
Cheng, C.Y.1
Su, C.C.2
-
9
-
-
74449089539
-
Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells
-
Tang C, Xue HL, Huang HB, Wang XG. Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells. Neurosci Lett. 2010; 470:126-129.
-
(2010)
Neurosci Lett
, vol.470
, pp. 126-129
-
-
Tang, C.1
Xue, H.L.2
Huang, H.B.3
Wang, X.G.4
-
10
-
-
73649126883
-
Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential
-
Chiu TL, Su CC. Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential. Int J Mol Med. 2010; 25:231-236.
-
(2010)
Int J Mol Med
, vol.25
, pp. 231-236
-
-
Chiu, T.L.1
Su, C.C.2
-
11
-
-
56249087235
-
Anticancer effects of tanshinone I in human non-small cell lung cancer
-
Lee CY, Sher HF, Chen HW, Liu CC, Chen CH, Lin CS, Yang PC, Tsay HS, Chen JJ. Anticancer effects of tanshinone I in human non-small cell lung cancer. Mol Cancer Ther. 2008; 7:3527-3538.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3527-3538
-
-
Lee, C.Y.1
Sher, H.F.2
Chen, H.W.3
Liu, C.C.4
Chen, C.H.5
Lin, C.S.6
Yang, P.C.7
Tsay, H.S.8
Chen, J.J.9
-
12
-
-
34248523334
-
Study of tanshinone IIA tissue distribution in rat by liquid chromatography-tandem mass spectrometry method
-
Bi HC, Law FC, Zhong GP, Xu CS, Pan Y, Ding L, Chen X, Zhao LZ, Xu Q, Huang M. Study of tanshinone IIA tissue distribution in rat by liquid chromatography-tandem mass spectrometry method. Biomed Chromatogr. 2007; 21:473-479.
-
(2007)
Biomed Chromatogr
, vol.21
, pp. 473-479
-
-
Bi, H.C.1
Law, F.C.2
Zhong, G.P.3
Xu, C.S.4
Pan, Y.5
Ding, L.6
Chen, X.7
Zhao, L.Z.8
Xu, Q.9
Huang, M.10
-
13
-
-
84879463275
-
Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function
-
Li Y, Gong Y, Li L, Abdolmaleky HM, Zhou JR. Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function. Mol Carcinog. 2013; 52:535-543.
-
(2013)
Mol Carcinog
, vol.52
, pp. 535-543
-
-
Li, Y.1
Gong, Y.2
Li, L.3
Abdolmaleky, H.M.4
Zhou, J.R.5
-
14
-
-
78449296222
-
MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma
-
Voortman J, Goto A, Mendiboure J, Sohn JJ, Schetter AJ, Saito M, Dunant A, Pham TC, Petrini I, Lee A, Khan MA, Hainaut P, Pignon JP, Brambilla E, Popper HH, Filipits M, et al. MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma. Cancer Res. 2010; 70:8288-8298.
-
(2010)
Cancer Res
, vol.70
, pp. 8288-8298
-
-
Voortman, J.1
Goto, A.2
Mendiboure, J.3
Sohn, J.J.4
Schetter, A.J.5
Saito, M.6
Dunant, A.7
Pham, T.C.8
Petrini, I.9
Lee, A.10
Khan, M.A.11
Hainaut, P.12
Pignon, J.P.13
Brambilla, E.14
Popper, H.H.15
Filipits, M.16
-
15
-
-
77952804693
-
MicroRNAs: novel biomarkers for human cancer
-
Bartels CL, Tsongalis GJ. [MicroRNAs: novel biomarkers for human cancer]Ann Biol Clin. Paris: 2010; 68:263-272.
-
(2010)
Ann Biol Clin. Paris
, vol.68
, pp. 263-272
-
-
Bartels, C.L.1
Tsongalis, G.J.2
-
16
-
-
80055092259
-
MicroRNAs, an active and versatile group in cancers
-
Liu J, Zheng M, Tang YL, Liang XH, Yang Q. MicroRNAs, an active and versatile group in cancers. Int J Oral Sci. 2011; 3:165-175.
-
(2011)
Int J Oral Sci
, vol.3
, pp. 165-175
-
-
Liu, J.1
Zheng, M.2
Tang, Y.L.3
Liang, X.H.4
Yang, Q.5
-
17
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR. MicroRNA expression profiles classify human cancers. Nature. 2005; 435:834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
18
-
-
84935520556
-
MicroRNA-34a inhibits the proliferation and promotes the apoptosis of non-small cell lung cancer H1299 cell line by targeting TGFbetaR2
-
Ma ZL, Hou PP, Li YL, Wang DT, Yuan TW, Wei JL, Zhao BT, Lou JT, Zhao XT, Jin Y, Jin YX. MicroRNA-34a inhibits the proliferation and promotes the apoptosis of non-small cell lung cancer H1299 cell line by targeting TGFbetaR2. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015; 36:2481-2490.
-
(2015)
Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine
, vol.36
, pp. 2481-2490
-
-
Ma, Z.L.1
Hou, P.P.2
Li, Y.L.3
Wang, D.T.4
Yuan, T.W.5
Wei, J.L.6
Zhao, B.T.7
Lou, J.T.8
Zhao, X.T.9
Jin, Y.10
Jin, Y.X.11
-
19
-
-
78649719325
-
miRNA expression profiling of lung adenocarcinomas: correlation with mutational status
-
Dacic S, Kelly L, Shuai Y, Nikiforova MN. miRNA expression profiling of lung adenocarcinomas: correlation with mutational status. Mod Pathol. 2010; 23:1577-1582.
-
(2010)
Mod Pathol
, vol.23
, pp. 1577-1582
-
-
Dacic, S.1
Kelly, L.2
Shuai, Y.3
Nikiforova, M.N.4
-
21
-
-
84888427208
-
microRNA-32 inhibits the proliferation and invasion of the SGC-901 gastric cancer cell line
-
Zhang J, Kuai X, Song M, Chen X, Yu Z, Zhang H, Mao Z. microRNA-32 inhibits the proliferation and invasion of the SGC-901 gastric cancer cell line. Oncol Lett. 2014; 7:270-274.
-
(2014)
Oncol Lett
, vol.7
, pp. 270-274
-
-
Zhang, J.1
Kuai, X.2
Song, M.3
Chen, X.4
Yu, Z.5
Zhang, H.6
Mao, Z.7
-
22
-
-
84867401829
-
Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer
-
Jalava SE, Urbanucci A, Latonen L, Waltering KK, Sahu B, Janne OA, Seppala J, Lahdesmaki H, Tammela TL, Visakorpi T. Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer. Oncogene. 2012; 31:4460-4471.
-
(2012)
Oncogene
, vol.31
, pp. 4460-4471
-
-
Jalava, S.E.1
Urbanucci, A.2
Latonen, L.3
Waltering, K.K.4
Sahu, B.5
Janne, O.A.6
Seppala, J.7
Lahdesmaki, H.8
Tammela, T.L.9
Visakorpi, T.10
-
24
-
-
84887110965
-
MiR-92b regulates the cell growth, cisplatin chemosensitivity of A549 non small cell lung cancer cell line and target PTEN
-
Li Y, Li L, Guan Y, Liu X, Meng Q, Guo Q. MiR-92b regulates the cell growth, cisplatin chemosensitivity of A549 non small cell lung cancer cell line and target PTEN. Biochem Biophys Res Commun. 2013; 440:604-610.
-
(2013)
Biochem Biophys Res Commun
, vol.440
, pp. 604-610
-
-
Li, Y.1
Li, L.2
Guan, Y.3
Liu, X.4
Meng, Q.5
Guo, Q.6
-
25
-
-
84905392759
-
MicroRNA-21 (miR-21) regulates cellular proliferation, invasion, migration, and apoptosis by targeting PTEN, RECK and Bcl-2 in lung squamous carcinoma, Gejiu City, China
-
Xu LF, Wu ZP, Chen Y, Zhu QS, Hamidi S, Navab R. MicroRNA-21 (miR-21) regulates cellular proliferation, invasion, migration, and apoptosis by targeting PTEN, RECK and Bcl-2 in lung squamous carcinoma, Gejiu City, China. PLoS One. 2014; 9:e103698.
-
(2014)
PLoS One
, vol.9
-
-
Xu, L.F.1
Wu, Z.P.2
Chen, Y.3
Zhu, Q.S.4
Hamidi, S.5
Navab, R.6
-
26
-
-
84908138114
-
MicroRNA-492 expression promotes the progression of hepatic cancer by targeting PTEN
-
Jiang J, Zhang Y, Yu C, Li Z, Pan Y, Sun C. MicroRNA-492 expression promotes the progression of hepatic cancer by targeting PTEN. Cancer Cell Int. 2014; 14:95.
-
(2014)
Cancer Cell Int
, vol.14
, pp. 95
-
-
Jiang, J.1
Zhang, Y.2
Yu, C.3
Li, Z.4
Pan, Y.5
Sun, C.6
-
27
-
-
84900484192
-
MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN
-
Geng L, Sun B, Gao B, Wang Z, Quan C, Wei F, Fang XD. MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN. Int J Mol Sci. 2014; 15:8458-8472.
-
(2014)
Int J Mol Sci
, vol.15
, pp. 8458-8472
-
-
Geng, L.1
Sun, B.2
Gao, B.3
Wang, Z.4
Quan, C.5
Wei, F.6
Fang, X.D.7
-
28
-
-
66249138523
-
RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN
-
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA. RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN. Cancer Res. 2009; 69:4107-4111.
-
(2009)
Cancer Res
, vol.69
, pp. 4107-4111
-
-
Park, S.1
Zhao, D.2
Hatanpaa, K.J.3
Mickey, B.E.4
Saha, D.5
Boothman, D.A.6
Story, M.D.7
Wong, E.T.8
Burma, S.9
Georgescu, M.M.10
Rangnekar, V.M.11
Chauncey, S.S.12
Habib, A.A.13
-
29
-
-
84880491054
-
Metastasis suppressor Nm23-H1 inhibits STAT3 signaling via a negative feedback mechanism
-
Gong L, Wu Z, Guo L, Li L, Zhao R, Zhu D, Zhou Q. Metastasis suppressor Nm23-H1 inhibits STAT3 signaling via a negative feedback mechanism. Biochem Biophys Res Commun. 2013; 434:541-546.
-
(2013)
Biochem Biophys Res Commun
, vol.434
, pp. 541-546
-
-
Gong, L.1
Wu, Z.2
Guo, L.3
Li, L.4
Zhao, R.5
Zhu, D.6
Zhou, Q.7
-
30
-
-
84875437100
-
IL-1 receptor regulates microRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation
-
Halappanavar S, Nikota J, Wu D, Williams A, Yauk CL, Stampfli M. IL-1 receptor regulates microRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation. J Immunol. 2013; 190:3679-3686.
-
(2013)
J Immunol
, vol.190
, pp. 3679-3686
-
-
Halappanavar, S.1
Nikota, J.2
Wu, D.3
Williams, A.4
Yauk, C.L.5
Stampfli, M.6
-
32
-
-
0141429171
-
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
-
Hirota T, Kunitoku N, Sasayama T, Marumoto T, Zhang D, Nitta M, Hatakeyama K, Saya H. Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell. 2003; 114:585-598.
-
(2003)
Cell
, vol.114
, pp. 585-598
-
-
Hirota, T.1
Kunitoku, N.2
Sasayama, T.3
Marumoto, T.4
Zhang, D.5
Nitta, M.6
Hatakeyama, K.7
Saya, H.8
-
33
-
-
67651146527
-
Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells
-
Kaestner P, Stolz A, Bastians H. Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells. Mol Cancer Ther. 2009; 8:2046-2056.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2046-2056
-
-
Kaestner, P.1
Stolz, A.2
Bastians, H.3
-
34
-
-
53149125697
-
Gene expression study of Aurora-A reveals implication during bladder carcinogenesis and increasing values in invasive urothelial cancer
-
Comperat E, Bieche I, Dargere D, Laurendeau I, Vieillefond A, Benoit G, Vidaud M, Camparo P, Capron F, Verret C, Cussenot O, Bedossa P, Paradis V. Gene expression study of Aurora-A reveals implication during bladder carcinogenesis and increasing values in invasive urothelial cancer. Urology. 2008; 72:873-877.
-
(2008)
Urology
, vol.72
, pp. 873-877
-
-
Comperat, E.1
Bieche, I.2
Dargere, D.3
Laurendeau, I.4
Vieillefond, A.5
Benoit, G.6
Vidaud, M.7
Camparo, P.8
Capron, F.9
Verret, C.10
Cussenot, O.11
Bedossa, P.12
Paradis, V.13
-
35
-
-
33744911634
-
Targeting Aurora kinases for the treatment of prostate cancer
-
Lee EC, Frolov A, Li R, Ayala G, Greenberg NM. Targeting Aurora kinases for the treatment of prostate cancer. Cancer Res. 2006; 66:4996-5002.
-
(2006)
Cancer Res
, vol.66
, pp. 4996-5002
-
-
Lee, E.C.1
Frolov, A.2
Li, R.3
Ayala, G.4
Greenberg, N.M.5
-
36
-
-
34948853830
-
Functional analysis of the Aurora Kinase A Ile31 allelic variant in human prostate
-
Matarasso N, Bar-Shira A, Rozovski U, Rosner S, Orr-Urtreger A. Functional analysis of the Aurora Kinase A Ile31 allelic variant in human prostate. Neoplasia. 2007; 9:707-715.
-
(2007)
Neoplasia
, vol.9
, pp. 707-715
-
-
Matarasso, N.1
Bar-Shira, A.2
Rozovski, U.3
Rosner, S.4
Orr-Urtreger, A.5
-
37
-
-
77953206216
-
Suppressed tumour growth and enhanced chemosensitivity by RNA interference targeting Aurora-A in the PC3 human prostate cancer model
-
Kumano M, Miyake H, Terakawa T, Furukawa J, Fujisawa M. Suppressed tumour growth and enhanced chemosensitivity by RNA interference targeting Aurora-A in the PC3 human prostate cancer model. BJU Int. 2010; 106:121-127.
-
(2010)
BJU Int
, vol.106
, pp. 121-127
-
-
Kumano, M.1
Miyake, H.2
Terakawa, T.3
Furukawa, J.4
Fujisawa, M.5
-
38
-
-
77949423993
-
RNAi-mediated knockdown of AURKB and EGFR shows enhanced therapeutic efficacy in prostate tumor regression
-
Addepalli MK, Ray KB, Kumar B, Ramnath RL, Chile S, Rao H. RNAi-mediated knockdown of AURKB and EGFR shows enhanced therapeutic efficacy in prostate tumor regression. Gene Ther. 2010; 17:352-359.
-
(2010)
Gene Ther
, vol.17
, pp. 352-359
-
-
Addepalli, M.K.1
Ray, K.B.2
Kumar, B.3
Ramnath, R.L.4
Chile, S.5
Rao, H.6
-
39
-
-
77954677274
-
VX680/MK-0457, a potent and selective Aurora kinase inhibitor, targets both tumor and endothelial cells in clear cell renal cell carcinoma
-
Li Y, Zhang ZF, Chen J, Huang D, Ding Y, Tan MH, Qian CN, Resau JH, Kim H, Teh BT. VX680/MK-0457, a potent and selective Aurora kinase inhibitor, targets both tumor and endothelial cells in clear cell renal cell carcinoma. Am J Transl Res. 2010; 2:296-308.
-
(2010)
Am J Transl Res
, vol.2
, pp. 296-308
-
-
Li, Y.1
Zhang, Z.F.2
Chen, J.3
Huang, D.4
Ding, Y.5
Tan, M.H.6
Qian, C.N.7
Resau, J.H.8
Kim, H.9
Teh, B.T.10
-
40
-
-
73549102150
-
Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis
-
Wang X, Dong L, Xie J, Tong T, Zhan Q. Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis. Cancer Biol Ther. 2009; 8:1852-1859.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1852-1859
-
-
Wang, X.1
Dong, L.2
Xie, J.3
Tong, T.4
Zhan, Q.5
-
41
-
-
76649120544
-
Aurora kinase inhibitors-rising stars in cancer therapeutics?
-
Dar AA, Goff LW, Majid S, Berlin J, El-Rifai W. Aurora kinase inhibitors-rising stars in cancer therapeutics? Mol Cancer Ther. 2010; 9:268-278.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 268-278
-
-
Dar, A.A.1
Goff, L.W.2
Majid, S.3
Berlin, J.4
El-Rifai, W.5
-
42
-
-
77954686021
-
A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma
-
Gorgun G, Calabrese E, Hideshima T, Ecsedy J, Perrone G, Mani M, Ikeda H, Bianchi G, Hu Y, Cirstea D, Santo L, Tai YT, Nahar S, Zheng M, Bandi M, Carrasco RD, et al. A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma. Blood. 2010; 115:5202-5213.
-
(2010)
Blood
, vol.115
, pp. 5202-5213
-
-
Gorgun, G.1
Calabrese, E.2
Hideshima, T.3
Ecsedy, J.4
Perrone, G.5
Mani, M.6
Ikeda, H.7
Bianchi, G.8
Hu, Y.9
Cirstea, D.10
Santo, L.11
Tai, Y.T.12
Nahar, S.13
Zheng, M.14
Bandi, M.15
Carrasco, R.D.16
-
43
-
-
75849151945
-
MicroRNA let-7: an emerging next-generation cancer therapeutic
-
Barh D, Malhotra R, Ravi B, Sindhurani P. MicroRNA let-7: an emerging next-generation cancer therapeutic. Curr Oncol. 2010; 17:70-80.
-
(2010)
Curr Oncol
, vol.17
, pp. 70-80
-
-
Barh, D.1
Malhotra, R.2
Ravi, B.3
Sindhurani, P.4
-
44
-
-
42049103216
-
The let-7 microRNA reduces tumor growth in mouse models of lung cancer
-
Esquela-Kerscher A, Trang P, Wiggins JF, Patrawala L, Cheng A, Ford L, Weidhaas JB, Brown D, Bader AG, Slack FJ. The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle. 2008; 7:759-764.
-
(2008)
Cell Cycle
, vol.7
, pp. 759-764
-
-
Esquela-Kerscher, A.1
Trang, P.2
Wiggins, J.F.3
Patrawala, L.4
Cheng, A.5
Ford, L.6
Weidhaas, J.B.7
Brown, D.8
Bader, A.G.9
Slack, F.J.10
-
45
-
-
78650194092
-
let-7 and miR-17-92: small-sized major players in lung cancer development
-
Osada H, Takahashi T. let-7 and miR-17-92: small-sized major players in lung cancer development. Cancer Sci. 2011; 102:9-17.
-
(2011)
Cancer Sci
, vol.102
, pp. 9-17
-
-
Osada, H.1
Takahashi, T.2
-
46
-
-
84935520556
-
MicroRNA-34a inhibits the proliferation and promotes the apoptosis of non-small cell lung cancer H1299 cell line by targeting TGFbetaR2
-
Ma ZL, Hou PP, Li YL, Wang DT, Yuan TW, Wei JL, Zhao BT, Lou JT, Zhao XT, Jin Y, Jin YX. MicroRNA-34a inhibits the proliferation and promotes the apoptosis of non-small cell lung cancer H1299 cell line by targeting TGFbetaR2. Tumour Biol. 2015; 36:2481-90.
-
(2015)
Tumour Biol
, vol.36
, pp. 2481-2490
-
-
Ma, Z.L.1
Hou, P.P.2
Li, Y.L.3
Wang, D.T.4
Yuan, T.W.5
Wei, J.L.6
Zhao, B.T.7
Lou, J.T.8
Zhao, X.T.9
Jin, Y.10
Jin, Y.X.11
-
47
-
-
79955913660
-
miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner
-
Bandi N, Vassella E. miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. Mol Cancer. 2011; 10:55.
-
(2011)
Mol Cancer
, vol.10
, pp. 55
-
-
Bandi, N.1
Vassella, E.2
-
48
-
-
84897042607
-
The microRNA miR-34a inhibits non-small cell lung cancer (NSCLC) growth and the CD44hi stem-like NSCLC cells
-
Shi Y, Liu C, Liu X, Tang DG, Wang J. The microRNA miR-34a inhibits non-small cell lung cancer (NSCLC) growth and the CD44hi stem-like NSCLC cells. PLoS One. 2014; 9:e90022.
-
(2014)
PLoS One
, vol.9
-
-
Shi, Y.1
Liu, C.2
Liu, X.3
Tang, D.G.4
Wang, J.5
-
49
-
-
84899482237
-
Inhibition of miR-25 improves cardiac contractility in the failing heart
-
Wahlquist C, Jeong D, Rojas-Munoz A, Kho C, Lee A, Mitsuyama S, van Mil A, Park WJ, Sluijter JP, Doevendans PA, Hajjar RJ, Mercola M. Inhibition of miR-25 improves cardiac contractility in the failing heart. Nature. 2014; 508:531-535.
-
(2014)
Nature
, vol.508
, pp. 531-535
-
-
Wahlquist, C.1
Jeong, D.2
Rojas-Munoz, A.3
Kho, C.4
Lee, A.5
Mitsuyama, S.6
van Mil, A.7
Park, W.J.8
Sluijter, J.P.9
Doevendans, P.A.10
Hajjar, R.J.11
Mercola, M.12
-
50
-
-
84907087913
-
MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin
-
Wang Z, Wang N, Liu P, Chen Q, Situ H, Xie T, Zhang J, Peng C, Lin Y, Chen J. MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin. Oncotarget. 2014; 5:7013-26.
-
(2014)
Oncotarget
, vol.5
, pp. 7013-7026
-
-
Wang, Z.1
Wang, N.2
Liu, P.3
Chen, Q.4
Situ, H.5
Xie, T.6
Zhang, J.7
Peng, C.8
Lin, Y.9
Chen, J.10
-
51
-
-
84922902863
-
miR-92a is upregulated in cervical cancer and promotes cell proliferation and invasion by targeting FBXW7
-
Zhou C, Shen L, Mao L, Wang B, Li Y, Yu H. miR-92a is upregulated in cervical cancer and promotes cell proliferation and invasion by targeting FBXW7. Biochemical and biophysical research communications. 2015; 458:63-69.
-
(2015)
Biochemical and biophysical research communications
, vol.458
, pp. 63-69
-
-
Zhou, C.1
Shen, L.2
Mao, L.3
Wang, B.4
Li, Y.5
Yu, H.6
-
52
-
-
9144251019
-
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53
-
Katayama H, Sasai K, Kawai H, Yuan ZM, Bondaruk J, Suzuki F, Fujii S, Arlinghaus RB, Czerniak BA, Sen S. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet. 2004; 36:55-62.
-
(2004)
Nat Genet
, vol.36
, pp. 55-62
-
-
Katayama, H.1
Sasai, K.2
Kawai, H.3
Yuan, Z.M.4
Bondaruk, J.5
Suzuki, F.6
Fujii, S.7
Arlinghaus, R.B.8
Czerniak, B.A.9
Sen, S.10
-
53
-
-
10644227569
-
Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215
-
Liu Q, Kaneko S, Yang L, Feldman RI, Nicosia SV, Chen J, Cheng JQ. Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215. J Biol Chem. 2004; 279:52175-52182.
-
(2004)
J Biol Chem
, vol.279
, pp. 52175-52182
-
-
Liu, Q.1
Kaneko, S.2
Yang, L.3
Feldman, R.I.4
Nicosia, S.V.5
Chen, J.6
Cheng, J.Q.7
-
54
-
-
84856347212
-
Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells
-
Li J, Wang K, Chen X, Meng H, Song M, Wang Y, Xu X, Bai Y. Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells. BMC Mol Biol. 2012; 13:4.
-
(2012)
BMC Mol Biol
, vol.13
, pp. 4
-
-
Li, J.1
Wang, K.2
Chen, X.3
Meng, H.4
Song, M.5
Wang, Y.6
Xu, X.7
Bai, Y.8
|