-
1
-
-
59949084951
-
Clinical cancer advances 2008: Major research advances in cancer treatment, prevention, and screening-a report from the American Society of Clinical Oncology
-
Winer E, Gralow J, Diller L, et al. Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening-a report from the American Society of Clinical Oncology. J Clin Oncol 2009;27:812-826.
-
(2009)
J Clin Oncol
, vol.27
, pp. 812-826
-
-
Winer, E.1
Gralow, J.2
Diller, L.3
-
3
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
4
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
5
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004;101:13306-13311.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
6
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou H, Dahabreh IJ, Kanaloupiti D, et al. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 2008;9:962-972.
-
(2008)
Lancet Oncol
, vol.9
, pp. 962-972
-
-
Linardou, H.1
Dahabreh, I.J.2
Kanaloupiti, D.3
-
7
-
-
55949097252
-
Genetic predictors of MEK dependence in non-small cell lung cancer
-
Pratilas CA, Hanrahan AJ, Halilovic E, et al. Genetic predictors of MEK dependence in non-small cell lung cancer. Cancer Res 2008;68:9375-9383.
-
(2008)
Cancer Res
, vol.68
, pp. 9375-9383
-
-
Pratilas, C.A.1
Hanrahan, A.J.2
Halilovic, E.3
-
8
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006;6:857-866.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
9
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 2004;101:2999-3004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
-
10
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, et al. MicroRNA expression profiles classify human cancers. Nature 2005;435: 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
-
11
-
-
33845624889
-
MicroRNAs in biological processes and carcinogenesis
-
Osada H, Takahashi T. MicroRNAs in biological processes and carcinogenesis. Carcinogenesis 2007;28: 2-12.
-
(2007)
Carcinogenesis
, vol.28
, pp. 2-12
-
-
Osada, H.1
Takahashi, T.2
-
12
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S, Calin GA, Liu C-G, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006;103: 2257-2261.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.-G.3
-
14
-
-
33846188098
-
Micrornas as oncogenes and tumor suppressors
-
Zhang B, Pan X, Cobb GP, et al. microRNAs as oncogenes and tumor suppressors. Dev Biol 2007;302:1-12.
-
(2007)
Dev Biol
, vol.302
, pp. 1-12
-
-
Zhang, B.1
Pan, X.2
Cobb, G.P.3
-
15
-
-
27244434788
-
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
Calin GA, Ferracin M, Cimmino A, et al. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 2005; 353:1793-1801.
-
(2005)
N Engl J Med
, vol.353
, pp. 1793-1801
-
-
Calin, G.A.1
Ferracin, M.2
Cimmino, A.3
-
16
-
-
38949111440
-
MicroRNAs as prognostic indicators and therapeutic targets: Potential effect on breast cancer management
-
Lowery AJ, Miller N, McNeill RE, et al. MicroRNAs as prognostic indicators and therapeutic targets: potential effect on breast cancer management. Clin Cancer Res 2008;14:360-365.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 360-365
-
-
Lowery, A.J.1
Miller, N.2
McNeill, R.E.3
-
17
-
-
33750600178
-
MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
-
Roldo C, Missiaglia E, Hagan JP, et al. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 2006; 24:4677-4684.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4677-4684
-
-
Roldo, C.1
Missiaglia, E.2
Hagan, J.P.3
-
18
-
-
38749089854
-
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
-
Schetter AJ, Leung SY, Sohn JJ, et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008;299:425-436.
-
(2008)
JAMA
, vol.299
, pp. 425-436
-
-
Schetter, A.J.1
Leung, S.Y.2
Sohn, J.J.3
-
19
-
-
33644819964
-
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
-
Yanaihara N, Caplen N, Bowman E, et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006;9:189-198.
-
(2006)
Cancer Cell
, vol.9
, pp. 189-198
-
-
Yanaihara, N.1
Caplen, N.2
Bowman, E.3
-
20
-
-
54249117763
-
0 untranslated region increases non-small cell lung cancer risk
-
0 untranslated region increases non-small cell lung cancer risk. Cancer Res 2008;68:8535-8540.
-
(2008)
Cancer Res
, vol.68
, pp. 8535-8540
-
-
Chin, L.J.1
Ratner, E.2
Leng, S.3
-
21
-
-
35748956868
-
Let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis
-
Inamura K, Togashi Y, Nomura K, et al. let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis. Lung Cancer 2007;58:392-396.
-
(2007)
Lung Cancer
, vol.58
, pp. 392-396
-
-
Inamura, K.1
Togashi, Y.2
Nomura, K.3
-
22
-
-
2542626605
-
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
-
Takamizawa J, Konishi H, Yanagisawa K, et al. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004;64:3753-3756.
-
(2004)
Cancer Res
, vol.64
, pp. 3753-3756
-
-
Takamizawa, J.1
Konishi, H.2
Yanagisawa, K.3
-
23
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell 2005;120: 635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
-
24
-
-
41649114199
-
Suppression of non-small cell lung tumor development by the let-7 microRNA family
-
Kumar MS, Erkeland SJ, Pester RE, et al. Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci USA 2008;105: 3903-3908.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3903-3908
-
-
Kumar, M.S.1
Erkeland, S.J.2
Pester, R.E.3
-
25
-
-
27544495514
-
A polycis-tronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
-
Hayashita Y, Osada H, Tatematsu Y, et al. A polycis-tronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005;65:9628-9632.
-
(2005)
Cancer Res
, vol.65
, pp. 9628-9632
-
-
Hayashita, Y.1
Osada, H.2
Tatematsu, Y.3
-
26
-
-
20444479428
-
C-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell KA, Wentzel EA, Zeller KI, et al. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005;435:839-843.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
-
27
-
-
67749110399
-
MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers
-
Seike M, Goto A, Okano T, et al. MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers. Proc Natl Acad Sci USA 2009;106: 12085-12090.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12085-12090
-
-
Seike, M.1
Goto, A.2
Okano, T.3
-
28
-
-
44849091213
-
EGFR regulation by microRNA in lung cancer: Correlation with clinical response and survival to gefitinib and EGFR expression in cell lines
-
Weiss GJ, Bemis LT, Nakajima E, et al. EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines. Ann Oncol 2008;19:1053-1059.
-
(2008)
Ann Oncol
, vol.19
, pp. 1053-1059
-
-
Weiss, G.J.1
Bemis, L.T.2
Nakajima, E.3
-
29
-
-
65549120766
-
Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7
-
Webster RJ, Giles KM, Price KJ, et al. Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J Biol Chem 2009;284: 5731-5741.
-
(2009)
J Biol Chem
, vol.284
, pp. 5731-5741
-
-
Webster, R.J.1
Giles, K.M.2
Price, K.J.3
-
30
-
-
43049180764
-
MicroRNA expression profiling of thyroid tumors: Biological significance and diagnostic utility
-
Nikiforova MN, Tseng GC, Steward D, et al. MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility. J Clin Endocrinol Metab 2008;93:1600-1608.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 1600-1608
-
-
Nikiforova, M.N.1
Tseng, G.C.2
Steward, D.3
-
31
-
-
0036127871
-
Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas
-
Nikiforova MN, Caudill CM, Biddinger P, et al. Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas. Int J Surg Pathol 2002;10:15-22.
-
(2002)
Int J Surg Pathol
, vol.10
, pp. 15-22
-
-
Nikiforova, M.N.1
Caudill, C.M.2
Biddinger, P.3
-
32
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, et al. Prediction of mammalian microRNA targets. Cell 2003;115: 787-798.
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
-
33
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, Grun D, Poy MN, et al. Combinatorial microRNA target predictions. Nat Genet 2005;37:495-500.
-
(2005)
Nat Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grun, D.2
Poy, M.N.3
-
34
-
-
77950467511
-
MicroRNA expression in human airway smooth muscle cells: Role of miR-25 in regulation of airway smooth muscle phenotype
-
Kuhn AR, Schlauch K, Lao R, et al. MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype. Am J Respir Cell Mol Biol 2010; 42:506-513.
-
Am J Respir Cell Mol Biol
, vol.2010
, Issue.42
, pp. 506-513
-
-
Kuhn, A.R.1
Schlauch, K.2
Lao, R.3
-
35
-
-
0344429906
-
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer
-
Ji P, Diederichs S, Wang W, et al. MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene 2003;22:8031-8041.
-
(2003)
Oncogene
, vol.22
, pp. 8031-8041
-
-
Ji, P.1
Diederichs, S.2
Wang, W.3
-
36
-
-
8444251099
-
Genome-wide screening for prognosis-predicting genes in early-stage non-small-cell lung cancer
-
Muller-Tidow C, Diederichs S, Thomas M, et al. Genome-wide screening for prognosis-predicting genes in early-stage non-small-cell lung cancer. Lung Cancer 2004;45(Suppl 2):S145-S150.
-
(2004)
Lung Cancer
, vol.45
, Issue.SUPPL. 2
-
-
Muller-Tidow, C.1
Diederichs, S.2
Thomas, M.3
-
37
-
-
25844465834
-
Loss of TSLC1 expression in lung adenocarcinoma: Relationships with histological subtypes, sex and prognostic significance
-
Goto A, Niki T, Chi-Pin L, et al. Loss of TSLC1 expression in lung adenocarcinoma: relationships with histological subtypes, sex and prognostic significance. Cancer Sci 2005;96:480-486.
-
(2005)
Cancer Sci
, vol.96
, pp. 480-486
-
-
Goto, A.1
Niki, T.2
Chi-Pin, L.3
-
38
-
-
42049090140
-
A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism
-
Vicent S, Luis-Ravelo D, Anton I, et al. A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism. Cancer Res 2008;68: 2275-2285.
-
(2008)
Cancer Res
, vol.68
, pp. 2275-2285
-
-
Vicent, S.1
Luis-Ravelo, D.2
Anton, I.3
-
39
-
-
51049103668
-
HMGA2 participates in transformation in human lung cancer
-
Di Cello F, Hillion J, Hristov A, et al. HMGA2 participates in transformation in human lung cancer. Mol Cancer Res 2008;6:743-750.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 743-750
-
-
Di Cello, F.1
Hillion, J.2
Hristov, A.3
-
40
-
-
67650999817
-
Suppression of nonhomologous end joining repair by overexpression of HMGA2
-
Li AYJ, Boo LM, Wang S-Y, et al. Suppression of nonhomologous end joining repair by overexpression of HMGA2. Cancer Res 2009;69:5699-5706.
-
(2009)
Cancer Res
, vol.69
, pp. 5699-5706
-
-
Ayj, L.1
Boo, L.M.2
Wang, S.-Y.3
|