Mouse Models of Rheumatoid Arthritis

Veterinary Pathology

Volumn 52, Issue 5, 2015, Pages 819-826

  Caplazi, P ^a   Baca, M ^a   Barck, K ^a   Carano, R A D ^a   DeVoss, J ^a   Lee, W P ^a   Bolon, B ^b   Diehl, L ^a  

^a GENENTECH INC   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

animal; arthritis; collagen antibody induced arthritis; collagen induced arthritis; experimental; k bxn antibody transfer arthritis; mice; models; rheumatoid; TNF ARE mouse

Indexed keywords

ANIMALIA; MUS;

COLLAGEN;

ANIMAL; ARTHRITIS; ARTHRITIS, RHEUMATOID; DISEASE MODEL; INFLAMMATION; MOUSE; PATHOLOGY; VETERINARY;

ANIMALS; ARTHRITIS; ARTHRITIS, RHEUMATOID; COLLAGEN; DISEASE MODELS, ANIMAL; INFLAMMATION; MICE;

EID: 84940197285     PISSN: 03009858     EISSN: 15442217     Source Type: Journal    
DOI: 10.1177/0300985815588612     Document Type: Article

References (71)

1. N.K.BandaS.HyattA.H.Antonioli. Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice. J Immunol. 2012;188:1469–1478.
2. K.H.BarckW.P.LeeL.J.Diehl. Quantification of cortical bone loss and repair for therapeutic evaluation in collagen-induced arthritis, by micro-computed tomography and automated image analysis. Arthritis Rheum. 2004;50:3377–3386.
3. B.BolonM.StolinaC.King. Rodent preclinical models for developing novel antiarthritic molecules: comparative biology and preferred methods for evaluating efficacy. J Biomed Biotechnol. 2011;2011:569068.
4. P.CaplaziL.J.Diehl. Histopathology in mouse models of rheumatoid arthritis. In: S.J.PottsD.A.EberhardK.Wharton, eds. Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development. New York, NY: Springer; in press.
5. E.CarballoW.S.LaiP.J.Blackshear. Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin. Science. 1998;281:1001–1005.
6. A.I.CatrinaA.J.YtterbergG.Reynisdottir. Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis. Nat Rev Rheumatol. 2014;10:645–653.
7. A.D.CookM.J.RowleyA.Stockman. Specificity of antibodies to type II collagen in early rheumatoid arthritis. J Rheumatol. 1994;21:1186–1191.
8. A.P.Cope. T cells in rheumatoid arthritis. Arthritis Res Ther. 2008;10(suppl 1):pS1.
9. K.N.CordovaV.C.WillisK.Haskins. A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis. J Immunol. 2013;190:1457–1465.
10. J.-M.DayerB.Bresnihan. Targeting interleukin-1 in treatment of rheumatoid arthrtitis. Arthritis Rheum. 2002;46:574–578.
11. N.DwivediM.Radic. Citrullination of autoantigens implicates NETosis in the induction of autoimmunity. Ann Rheum Dis. 2014;73:483–491.
12. S.EyreJ.BowesD.Diogo. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet. 2012;44:1336–1340.
13. M.H.García-HernándezR.González-AmaroD.P.Portales-Pérez. Specific therapy to regulate inflammation in rheumatoid arthritis: molecular aspects. Immunotherapy. 2014;6:623–636.
14. S.D.GauldieD.S.McQueenC.J.Clarke. A robust model of adjuvant-induced chronic unilateral arthritis in two mouse strains. J Neurosci Methods. 2004;139:281–291.
15. R.Holmdahl. Primer: comparative genetics of animal models of arthritis—a tool to resolve complexity. Nat Clin Pract Rheumatol. 2007;3:104–111.
16. R.HolmdahlL.JanssonE.Larsson. Homologous type II collagen induces chronic and progressive arthritis in mice. Arthritis Rheum. 1986;29:106–113.
17. R.HolmdahlJ.MoC.Nordling. Collagen induced arthritis: an experimental model for rheumatoid arthritis with involvement of both DTH and immune complex mediated mechanisms. Clin Exp Rheumatol. 1989;7(suppl 3):S51–S55.
18. R.HoraiA.NakajimaK.Habiro. TNFa is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice. J Clin Invest. 2004;114:1603–1611.
19. R.HoraiS.SaijoH.Tanioka. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J Exp Med. 2000;191:313–320.
20. S.HuybersM.ApostolakiB.C.J.van der Eerden. Murine TNF(DeltaARE) Crohn’s disease model displays diminished expression of intestinal Ca2+ transporters. Inflamm Bowel Dis. 2008;14:803–811.
21. J.B.Imboden. The immunopathogenesis of rheumatoid arthritis. Annu Rev Pathol. 2009;4:417–434.
22. H.KelchtermansA.BilliauP.Matthys. How interferon-gamma keeps autoimmune diseases in check. Trends Immunol. 2008;29(10):479–486.
23. L.M.Khachigian. Collagen antibody-induced arthritis. Nat Protoc. 2006;1:2512–2516.
24. B.A.KiddP.P.HoO.Sharpe. Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination. Arthritis Res Ther. 2008;10:R119.
25. M.I.KoendersI.DevesaR.J.Marijnissen. Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in Interleukin-1 receptor antagonist-deficient mice. Arthritis Rheum. 2008;58:3461–3470.
26. D.KontoyiannisM.PasparakisT.T.Pizarro. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity. 1999;10:387–398.
27. V.KouskoffA.S.KorganowV.Duchatelle. Organ-specific disease provoked by systemic autoimmunity. Cell. 1996;87:811–822.
28. K.A.KuhnL.KulikB.Tomooka. Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis. J Clin Invest. 2006;116:961–973.
29. S.Kundu-RaychaudhuriA.MitraA.Datta-Mitra. In vivo quantification of mouse autoimmune arthritis by PET/CT [published online June 26, 2014]. Int J Rheum Dis.
30. J.LeipeA.SkapenkoP.E.Lipsky. Regulatory T cells in rheumatoid arthritis. Arthritis Res Ther. 2005;7:93–99.
31. M.MaccioniG.Zeder-LutzH.Huang. Arthritogenic monoclonal antibodies from K/BxN mice. J Exp Med. 2002;195:1071–1077.
32. H.MarkidesO.KehoeR.H.Morris. Whole body tracking of superparamagnetic iron oxide nanoparticle-labelled cells: a rheumatoid arthritis mouse model. Stem Cell Res Ther. 2013;4:126.
33. S.MihaiF.Nimmerjahn. The role of Fc receptors and complement in autoimmunity. Autoimmun Rev. 2013;12:657–660.
34. P.MonachK.HattoriH.Huang. The K/BxN mouse model of inflammatory arthritis: theory and practice. Methods Mol Med. 2007;136:269–282.
35. S.MullerM.Radic. Citrullinated autoantigens: from diagnostic markers to pathogenetic mechanisms [published online October 30, 2014]. Clin Rev Allergy Immunol.
36. S.NakaeS.SaijoR.Horai. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc Natl Acad Sci U S A. 2003;100:5896–5990.
37. K.S.NandakumarJ.BäcklundM.Vestberg. Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells. Arthritis Res Ther. 2004;6:R544–R550.
38. K.S.NandakumarR.Holmdahl. Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis. Arthritis Res Ther. 2006;8:223.
39. K.S.NandakumarR.Holmdahl. Collagen antibody-induced arthritis. Methods Mol Med. 2007;136:215–223.
40. K.S.NandakumarL.SvenssonR.Holmdahl. Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes. Am J Pathol. 2003;163:1827–1837.
41. M.J.ParkH.S.ParkH.J.Oh. IL-17-deficient allogeneic bone marrow transplantation prevents the induction of collagen-induced arthritis in DBA/1J mice. Exp Mol Med. 2012;44:694–705.
42. S.S.ParvathyW.Masocha. Gait analysis of C57BL/6 mice with complete Freund’s adjuvant-induced arthritis using the CatWalk system. BMC Musculoskelet Disord. 2013;14:14.
43. C.PattenK.BushI.Rioja. Characterization of pristane-induced arthritis, a murine model of chronic disease: response to antirheumatic agents, expression of joint cytokines, and immunopathology. Arthritis Rheum. 2004;50:3334–3345.
44. M.PotterJ.S.Wax. Genetics of susceptibility to pristane-induced plasmacytomas in BALB/cAn: reduced susceptibility in BALB/cJ with a brief description of pristane-induced arthritis. J Immunol. 1981;127:1591–1595.
45. L.M.RaneaA.de Castro MarquesS.Möller. Genetic control of spontaneous arthritis in a four-way advanced intercross line. PLoS ONE. 2013;8:e75611.
46. S.RaychaudhuriC.SandorE.A.Stahl. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat Genet. 2012;44:291–296.
47. K.RedlichB.GörtzS.Hayer. Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis. Am J Pathol. 2004;164:543–555.
48. S.SakaguchiH.BenhamA.P.Cope. T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man. Immunology and Cell Biology. 2012;90:277–287.
49. M.SamsonS.AudiaN.Janikashvili. Inhibition of Interleukin-6 function corrects Th17/Treg cell imbalance in patients with rheumatoid arthritis. Arthritis Rheum. 2012;64:2499–2503.
50. S.SarkarS.JustaM.Brucks. Interleukin (IL)-17A, F and AF in inflammation: a study in collagen-induced arthritis and rheumatoid arthritis. Clin Exp Immunol. 2014;177:652–661.
51. E.SchurgersA.BilliauP.Matthys. Collagen-induced arthritis as an animal model for rheumatoid arthritis: focus on interferon-γ. J Interferon Cytokine Res. 2011;31:917–926.
52. J.SokoloveR.BrombergK.D.Deane. Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis. PLoS ONE. 2012;7:e35296.
53. J.M.StuartF.J.Dixon. Serum transfer of collagen-induced arthritis in mice. J Exp Med. 1983;158:378–392.
54. Y.SunP.CaplaziJ.Zhang. PILR negatively regulates mouse inflammatory arthritis. J Immunol. 2014;193:860–870.
55. P.SvendsenC.B.AndersenN.Willcox. Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice. J Immunol. 2004;173:7037–7045.
56. A.TarkowskiL.KlareskogH.Carlsten. Secretion of antibodies to types I and II collagen by synovial tissue cells in patients with rheumatoid arthritis. Arthritis Rheum. 1989;32:1087–1092.
57. K.TeratoK.A.HastyR.A.Reife. Induction of arthritis with monoclonal antibodies to collagen. J Immunol. 1992;148:2103–2108.
58. G.M.ThieleM.J.DuryeeA.Dusad. Citrullinated mouse collagen administered to DBA/1J mice in the absence of adjuvant initiates arthritis. Int Immunopharmacol. 2012;13:424–431.
59. D.E.TrenthamA.S.TownesA.H.Kang. Autoimmunity to type II collagen an experimental model of arthritis. J Exp Med. 1977;146:857–868.
60. G.ValesiniM.C.GerardiC.Iannuccelli. Citrullination and autoimmunity. Autoimmun Rev. 2015;14:490–497.
61. R.F.van Vollenhoven. Rheumatoid arthritis in 2012: progress in RA genetics, pathology and therapy. Nat Rev Rheumatol. 2013;9:70–72.
62. E.van WijkM.KobayashiR.van Wijk. Imaging of ultra-weak photon emission in a rheumatoid arthritis mouse model. PLoS ONE. 2013;8:e84579.
63. T.L.VincentR.O.WilliamsR.Maciewicz. Mapping pathogenesis of arthritis through small animal models. Rheumatology. 2012;51:1931–1941.
64. E.R.VossenaarW.H.Robinson. Citrullination and autoimmune disease: 8th Bertine Koperberg meeting. Ann Rheum Dis. 2005;64(10):1513–1515.
65. B.H.Waksman. Immune regulation in adjuvant disease and other arthritis models: relevance to pathogenesis of chronic arthritis. Scand J Immunol. 2002;56:12–34.
66. R.O.Williams. Collagen-induced arthritis in mice. Methods Mol Med. 2007;136:191–199.
67. B.T.WipkeP.M.Allen. Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J Immunol. 2001;167:1601–1608.
68. P.H.WooleyH.S.LuthraS.K.Singh. Passive transfer of arthritis to mice by injection of human anti-type II collagen antibody. Mayo Clinic Proceedings. 1984;59:737–743.
69. P.H.WooleyH.S.LuthraJ.M.Stuart. Type II collagen-induced arthritis in mice: I. Major histocompatibility complex (I region) linkage and antibody correlates. J Exp Med. 1981;154:688–700.
70. H.L.WrightR.J.MootsS.W.Edwards. The multifactorial role of neutrophils in rheumatoid arthritis. Nat Rev Rheumatol. 2014;10:593–601.
71. F.ZhengS.PutL.Bouwens. Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis. J Nucl Med. 2014;55:824–829.