-
1
-
-
84861920191
-
Nonalcoholic fatty liver disease: the hepatic metabolic syndrome
-
Page J. Nonalcoholic fatty liver disease: the hepatic metabolic syndrome. J Am Acad Nurse Pract 2012; 24: 345-51.
-
(2012)
J Am Acad Nurse Pract
, vol.24
, pp. 345-351
-
-
Page, J.1
-
2
-
-
77954375834
-
The challenge of developing novel pharmacological therapies for non-alcoholic steatohepatitis
-
Schuppan D, Gorrell MD, Klein T, Mark M, Afdhal NH. The challenge of developing novel pharmacological therapies for non-alcoholic steatohepatitis. Liver Int 2010; 30: 795-808.
-
(2010)
Liver Int
, vol.30
, pp. 795-808
-
-
Schuppan, D.1
Gorrell, M.D.2
Klein, T.3
Mark, M.4
Afdhal, N.H.5
-
5
-
-
81855213130
-
Nonalcoholic steatohepatitis: the therapeutic challenge of a global epidemic
-
Schattenberg JM, Schuppan D. Nonalcoholic steatohepatitis: the therapeutic challenge of a global epidemic. Curr Opin Lipidol 2011; 22: 479-88.
-
(2011)
Curr Opin Lipidol
, vol.22
, pp. 479-488
-
-
Schattenberg, J.M.1
Schuppan, D.2
-
6
-
-
44649095633
-
Review article: current management of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
-
Younossi ZM. Review article: current management of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Aliment Pharmacol Ther 2008; 28: 2-12.
-
(2008)
Aliment Pharmacol Ther
, vol.28
, pp. 2-12
-
-
Younossi, Z.M.1
-
7
-
-
33748789479
-
Mediators of endoplasmic reticulum stress-induced apoptosis
-
Szegezdi E, Logue SE, Gorman AM, Samali A. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 2006; 7: 880-5.
-
(2006)
EMBO Rep
, vol.7
, pp. 880-885
-
-
Szegezdi, E.1
Logue, S.E.2
Gorman, A.M.3
Samali, A.4
-
8
-
-
57049117856
-
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
-
Kim I, Xu W, Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 2008; 7: 1013-30.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 1013-1030
-
-
Kim, I.1
Xu, W.2
Reed, J.C.3
-
9
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011; 334: 1081-6.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
10
-
-
33749492425
-
Endoplasmic reticulum stress signaling in disease
-
Marciniak SJ, Ron D. Endoplasmic reticulum stress signaling in disease. Physiol Rev 2006; 86: 1133-49.
-
(2006)
Physiol Rev
, vol.86
, pp. 1133-1149
-
-
Marciniak, S.J.1
Ron, D.2
-
11
-
-
33745844503
-
Endoplasmic reticulum stress in health and disease
-
Zhao L, Ackerman SL. Endoplasmic reticulum stress in health and disease. Curr Opin Cell Biol 2006; 18: 444-52.
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 444-452
-
-
Zhao, L.1
Ackerman, S.L.2
-
12
-
-
79954424574
-
Human prion protein mutants with deleted and inserted octarepeats undergo different pathways to trigger cell apoptosis
-
Xu K, Wang X, Shi Q etal. Human prion protein mutants with deleted and inserted octarepeats undergo different pathways to trigger cell apoptosis. J Mol Neurosci 2011; 43: 225-34.
-
(2011)
J Mol Neurosci
, vol.43
, pp. 225-234
-
-
Xu, K.1
Wang, X.2
Shi, Q.3
-
13
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
Feldstein AE, Canbay A, Angulo P etal. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 2003; 125: 437-43.
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
-
14
-
-
1242336980
-
Apoptosis: the nexus of liver injury and fibrosis
-
Canbay A, Friedman S, Gores GJ. Apoptosis: the nexus of liver injury and fibrosis. Hepatology 2004; 39: 273-8.
-
(2004)
Hepatology
, vol.39
, pp. 273-278
-
-
Canbay, A.1
Friedman, S.2
Gores, G.J.3
-
15
-
-
2442487968
-
ERp19 and ERp46, new members of the thioredoxin family of endoplasmic reticulum proteins
-
Knoblach B, Keller BO, Groenendyk J etal. ERp19 and ERp46, new members of the thioredoxin family of endoplasmic reticulum proteins. Mol Cell Proteomics 2003; 2: 1104-19.
-
(2003)
Mol Cell Proteomics
, vol.2
, pp. 1104-1119
-
-
Knoblach, B.1
Keller, B.O.2
Groenendyk, J.3
-
16
-
-
0344443678
-
EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor
-
Sullivan DC, Huminiecki L, Moore JW etal. EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor. J Biol Chem 2003; 278: 47079-88.
-
(2003)
J Biol Chem
, vol.278
, pp. 47079-47088
-
-
Sullivan, D.C.1
Huminiecki, L.2
Moore, J.W.3
-
17
-
-
14044271131
-
The human protein disulphide isomerase family: substrate interactions and functional properties
-
Ellgaard L, Ruddock LW. The human protein disulphide isomerase family: substrate interactions and functional properties. EMBO Rep 2005; 6: 28-32.
-
(2005)
EMBO Rep
, vol.6
, pp. 28-32
-
-
Ellgaard, L.1
Ruddock, L.W.2
-
18
-
-
69049119359
-
ERp46 is reduced by high glucose and regulates insulin content in pancreatic β-cells
-
Alberti A, Karamessinis P, Peroulis M etal. ERp46 is reduced by high glucose and regulates insulin content in pancreatic β-cells. Am J Physiol Endocrinol Metab 2009; 297: E812-21.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
, pp. E812-E821
-
-
Alberti, A.1
Karamessinis, P.2
Peroulis, M.3
-
19
-
-
84866888146
-
Role of ERp46 in β-cell lipoapoptosis through endoplasmic reticulum stress pathway as well as the protective effect of exendin-4
-
Chen DL, Xiang JN, Yang LY. Role of ERp46 in β-cell lipoapoptosis through endoplasmic reticulum stress pathway as well as the protective effect of exendin-4. Biochem Biophys Res Commun 2012; 426: 324-9.
-
(2012)
Biochem Biophys Res Commun
, vol.426
, pp. 324-329
-
-
Chen, D.L.1
Xiang, J.N.2
Yang, L.Y.3
-
20
-
-
0032966882
-
Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
-
Gutzwiller JP, Drewe J, Goke B etal. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am J Physiol 1999; 276: R1541-4.
-
(1999)
Am J Physiol
, vol.276
, pp. R1541-R1544
-
-
Gutzwiller, J.P.1
Drewe, J.2
Goke, B.3
-
21
-
-
34250635159
-
GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting
-
Korner M, Stockli M, Waser B, Reubi JC. GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting. J Nucl Med 2007; 48: 736-43.
-
(2007)
J Nucl Med
, vol.48
, pp. 736-743
-
-
Korner, M.1
Stockli, M.2
Waser, B.3
Reubi, J.C.4
-
22
-
-
77951436599
-
Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway
-
Gupta NA, Mells J, Dunham RM etal. Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway. Hepatology 2010; 51: 1584-92.
-
(2010)
Hepatology
, vol.51
, pp. 1584-1592
-
-
Gupta, N.A.1
Mells, J.2
Dunham, R.M.3
-
23
-
-
33644803761
-
Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice
-
Ding X, Saxena NK, Lin S, Gupta NA, Anania FA. Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice. Hepatology 2006; 43: 173-81.
-
(2006)
Hepatology
, vol.43
, pp. 173-181
-
-
Ding, X.1
Saxena, N.K.2
Lin, S.3
Gupta, N.A.4
Anania, F.A.5
-
24
-
-
79956114434
-
Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase
-
Ben-Shlomo S, Zvibel I, Shnell M etal. Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase. J Hepatol 2011; 54: 1214-23.
-
(2011)
J Hepatol
, vol.54
, pp. 1214-1223
-
-
Ben-Shlomo, S.1
Zvibel, I.2
Shnell, M.3
-
25
-
-
79954631160
-
The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes
-
Shimoda M, Kanda Y, Hamamoto S etal. The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes. Diabetologia 2011; 54: 1098-108.
-
(2011)
Diabetologia
, vol.54
, pp. 1098-1108
-
-
Shimoda, M.1
Kanda, Y.2
Hamamoto, S.3
-
26
-
-
84865224952
-
Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits cell apoptosis induced by lipotoxicity in pancreatic beta-cell line
-
Wei Q, Sun YQ, Zhang J. Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits cell apoptosis induced by lipotoxicity in pancreatic beta-cell line. Peptides 2012; 37: 18-24.
-
(2012)
Peptides
, vol.37
, pp. 18-24
-
-
Wei, Q.1
Sun, Y.Q.2
Zhang, J.3
-
27
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
Kleiner DE, Brunt EM, Van Natta M etal. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-21.
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
-
28
-
-
84865062709
-
Downregulation of chemerin and alleviation of endoplasmic reticulum stress by metformin in adipose tissue of rats
-
Pei L, Yang J, Du J, Liu H, Ao N, Zhang Y. Downregulation of chemerin and alleviation of endoplasmic reticulum stress by metformin in adipose tissue of rats. Diabetes Res Clin Pract 2012; 97: 267-75.
-
(2012)
Diabetes Res Clin Pract
, vol.97
, pp. 267-275
-
-
Pei, L.1
Yang, J.2
Du, J.3
Liu, H.4
Ao, N.5
Zhang, Y.6
-
29
-
-
84857185142
-
Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice
-
Lee J, Hong SW, Chae SW etal. Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice. PLoS One 2012; 7: e31394.
-
(2012)
PLoS One
, vol.7
-
-
Lee, J.1
Hong, S.W.2
Chae, S.W.3
-
30
-
-
80052517174
-
Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis
-
Svegliati-Baroni G, Saccomanno S, Rychlicki C etal. Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis. Liver Int 2011; 31: 1285-97.
-
(2011)
Liver Int
, vol.31
, pp. 1285-1297
-
-
Svegliati-Baroni, G.1
Saccomanno, S.2
Rychlicki, C.3
-
31
-
-
84905397741
-
Potential roles of glucagon-like peptide-1-based therapies in treating non-alcoholic fatty liver disease
-
Liu Y, Wei R, Hong TP. Potential roles of glucagon-like peptide-1-based therapies in treating non-alcoholic fatty liver disease. World J Gastroenterol 2014; 20: 9090-7.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 9090-9097
-
-
Liu, Y.1
Wei, R.2
Hong, T.P.3
-
32
-
-
84876088714
-
GLP-1 analogue prevents NAFLD in ApoE KO mice with diet and Acrp30 knockdown by inhibiting c-JNK
-
Zhang L, Yang M, Ren H etal. GLP-1 analogue prevents NAFLD in ApoE KO mice with diet and Acrp30 knockdown by inhibiting c-JNK. Liver Int 2013; 33: 794-804.
-
(2013)
Liver Int
, vol.33
, pp. 794-804
-
-
Zhang, L.1
Yang, M.2
Ren, H.3
-
33
-
-
84910603708
-
Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflammation
-
Wang XC, Gusdon AM, Liu H, Qu S. Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflammation. World J Gastroenterol 2014; 20: 14821-30.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 14821-14830
-
-
Wang, X.C.1
Gusdon, A.M.2
Liu, H.3
Qu, S.4
-
34
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E etal. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004; 306: 457-61.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
-
35
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010; 140: 900-17.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
36
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004; 11: 381-9.
-
(2004)
Cell Death Differ
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
37
-
-
27744500069
-
Endoplasmic reticulum stress-associated caspase 12 mediates cisplatin-induced LLC-PK1 cell apoptosis
-
Liu H, Baliga R. Endoplasmic reticulum stress-associated caspase 12 mediates cisplatin-induced LLC-PK1 cell apoptosis. J Am Soc Nephrol 2005; 16: 1985-92.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1985-1992
-
-
Liu, H.1
Baliga, R.2
-
38
-
-
75749115950
-
ERp46 binds to AdipoR1, but not AdipoR2, and modulates adiponectin signalling
-
Charlton HK, Webster J, Kruger S, Simpson F, Richards AA, Whitehead JP. ERp46 binds to AdipoR1, but not AdipoR2, and modulates adiponectin signalling. Biochem Biophys Res Commun 2010; 392: 234-9.
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 234-239
-
-
Charlton, H.K.1
Webster, J.2
Kruger, S.3
Simpson, F.4
Richards, A.A.5
Whitehead, J.P.6
-
39
-
-
24044453711
-
Proteomic profiling of hepatic endoplasmic reticulum-associated proteins in an animal model of insulin resistance and metabolic dyslipidemia
-
Morand JP, Macri J, Adeli K. Proteomic profiling of hepatic endoplasmic reticulum-associated proteins in an animal model of insulin resistance and metabolic dyslipidemia. J Biol Chem 2005; 280: 17626-33.
-
(2005)
J Biol Chem
, vol.280
, pp. 17626-17633
-
-
Morand, J.P.1
Macri, J.2
Adeli, K.3
|