-
1
-
-
84889591757
-
Tissue-type plasminogen activator mediates neuroglial coupling in the central nervous system
-
An, J., Haile, W. B., Wu, F., Torre, E., and Yepes, M. (2014). Tissue-type plasminogen activator mediates neuroglial coupling in the central nervous system. Neuroscience 257, 41-48. doi: 10.1016/j.neuroscience.2013.10.060
-
(2014)
Neuroscience
, vol.257
, pp. 41-48
-
-
An, J.1
Haile, W.B.2
Wu, F.3
Torre, E.4
Yepes, M.5
-
2
-
-
0032192461
-
Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway
-
Baranes, D., Lederfein, D., Huang, Y. Y., Chen, M., Bailey, C. H., and Kandel, E. R. (1998). Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway. Neuron 21, 813-825. doi: 10.1016/s0896-6273(00)80597-8
-
(1998)
Neuron
, vol.21
, pp. 813-825
-
-
Baranes, D.1
Lederfein, D.2
Huang, Y.Y.3
Chen, M.4
Bailey, C.H.5
Kandel, E.R.6
-
3
-
-
26844435654
-
Rodent models of focal stroke: Size, mechanism and purpose
-
Carmichael, S. T. (2005). Rodent models of focal stroke: size, mechanism and purpose. NeuroRx 2, 396-409. doi: 10.1602/neurorx.2.3.396
-
(2005)
NeuroRx
, vol.2
, pp. 396-409
-
-
Carmichael, S.T.1
-
4
-
-
0031470554
-
Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin
-
Chen, Z. L., and Strickland, S. (1997). Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin. Cell 91, 917-925. doi: 10.1016/s0092-8674(00)80483-3
-
(1997)
Cell
, vol.91
, pp. 917-925
-
-
Chen, Z.L.1
Strickland, S.2
-
5
-
-
0024093449
-
Glutamate neurotoxicity and diseases of the nervous system
-
Choi, D. W. (1988). Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634. doi: 10.1016/0896-6273(88)90162-6
-
(1988)
Neuron
, vol.1
, pp. 623-634
-
-
Choi, D.W.1
-
6
-
-
0035652035
-
Neuroserpin, a neuroprotective factor in focal ischemic stroke
-
Cinelli, P., Madani, R., Tsuzuki, N., Vallet, P., Arras, M., Zhao, C. N., et al. (2001). Neuroserpin, a neuroprotective factor in focal ischemic stroke. Mol. Cell. Neurosci. 18, 443-457. doi: 10.1006/mcne.2001.1028
-
(2001)
Mol. Cell. Neurosci
, vol.18
, pp. 443-457
-
-
Cinelli, P.1
Madani, R.2
Tsuzuki, N.3
Vallet, P.4
Arras, M.5
Zhao, C.N.6
-
7
-
-
84883405401
-
Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait
-
Cops, E. J., Sashindranath, M., Daglas, M., Short, K. M., da Fonseca Pereira, C., Pang, T. Y., et al. (2013). Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait. Exp. Neurol. 249, 8-19. doi: 10.1016/j.expneurol.2013.08.001
-
(2013)
Exp. Neurol
, vol.249
, pp. 8-19
-
-
Cops, E.J.1
Sashindranath, M.2
Daglas, M.3
Short, K.M.4
da Fonseca Pereira, C.5
Pang, T.Y.6
-
8
-
-
0033951941
-
Selfotel in acute ischemic stroke: Possible neurotoxic effects of an NMDA antagonist
-
Davis, S. M., Lees, K. R., Albers, G. W., Diener, H. C., Markabi, S., Karlsson, G., et al. (2000). Selfotel in acute ischemic stroke: possible neurotoxic effects of an NMDA antagonist. Stroke 31, 347-354. doi: 10.1161/01.str.31.2.347
-
(2000)
Stroke
, vol.31
, pp. 347-354
-
-
Davis, S.M.1
Lees, K.R.2
Albers, G.W.3
Diener, H.C.4
Markabi, S.5
Karlsson, G.6
-
9
-
-
77953182892
-
Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus
-
Echeverry, R., Wu, J., Haile, W. B., Guzman, J., and Yepes, M. (2010). Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus. J. Clin. Invest. 120, 2194-2205. doi: 10.1172/JCI41722
-
(2010)
J. Clin. Invest
, vol.120
, pp. 2194-2205
-
-
Echeverry, R.1
Wu, J.2
Haile, W.B.3
Guzman, J.4
Yepes, M.5
-
10
-
-
0029886174
-
Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator
-
Gualandris, A., Jones, T. E., Strickland, S., and Tsirka, S. E. (1996). Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator. J. Neurosci. 16, 2220-2225.
-
(1996)
J. Neurosci
, vol.16
, pp. 2220-2225
-
-
Gualandris, A.1
Jones, T.E.2
Strickland, S.3
Tsirka, S.E.4
-
11
-
-
1542315556
-
Association of outcome with early stroke treatment: Pooled analysis of ATLANTIS, ECASS and NINDS rt-PA stroke trials
-
Hacke, W., Donnan, G., Fieschi, C., Kaste, M., von Kummer, R., Broderick, J. P., et al. (2004). Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS and NINDS rt-PA stroke trials. Lancet 363, 768-774. doi: 10.1016/s0140-6736(04)15692-4
-
(2004)
Lancet
, vol.363
, pp. 768-774
-
-
Hacke, W.1
Donnan, G.2
Fieschi, C.3
Kaste, M.4
von Kummer, R.5
Broderick, J.P.6
-
12
-
-
77952009799
-
Human recombinant tissue-plasminogen activator (alteplase): Why not use the 'human' dose for stroke studies in rats?
-
Haelewyn, B., Risso, J. J., and Abraini, J. H. (2010). Human recombinant tissue-plasminogen activator (alteplase): why not use the 'human' dose for stroke studies in rats? J. Cereb. Blood Flow Metab. 30, 900-903. doi: 10.1038/jcbfm.2010.33
-
(2010)
J. Cereb. Blood Flow Metab
, vol.30
, pp. 900-903
-
-
Haelewyn, B.1
Risso, J.J.2
Abraini, J.H.3
-
13
-
-
84855347516
-
Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α
-
Haile, W. B., Wu, J., Echeverry, R., Wu, F., An, J., and Yepes, M. (2012). Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α. J. Cereb. Blood Flow Metab. 32, 57-69. doi: 10.1038/jcbfm.2011.106
-
(2012)
J. Cereb. Blood Flow Metab
, vol.32
, pp. 57-69
-
-
Haile, W.B.1
Wu, J.2
Echeverry, R.3
Wu, F.4
An, J.5
Yepes, M.6
-
14
-
-
0018903975
-
Brain extracellular space during spreading depression and ischemia
-
Hansen, A. J., and Olsen, C. E. (1980). Brain extracellular space during spreading depression and ischemia. Acta Physiol. Scand. 108, 355-365. doi: 10.1111/j.1748-1716.1980.tb06544.x
-
(1980)
Acta Physiol. Scand
, vol.108
, pp. 355-365
-
-
Hansen, A.J.1
Olsen, C.E.2
-
15
-
-
77956917231
-
Synaptic versus extrasynaptic NMDA receptor signalling: Implications for neurodegenerative disorders
-
Hardingham, G. E., and Bading, H. (2010). Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat. Rev. Neurosci. 11, 682-696. doi: 10.1038/nrn2911
-
(2010)
Nat. Rev. Neurosci
, vol.11
, pp. 682-696
-
-
Hardingham, G.E.1
Bading, H.2
-
16
-
-
0031452755
-
Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival
-
Hastings, G. A., Coleman, T. A., Haudenschild, C. C., Stefansson, S., Smith, E. P., Barthlow, R., et al. (1997). Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival. J. Biol. Chem. 272, 33062-33067. doi: 10.1074/jbc.272.52.33062
-
(1997)
J. Biol. Chem
, vol.272
, pp. 33062-33067
-
-
Hastings, G.A.1
Coleman, T.A.2
Haudenschild, C.C.3
Stefansson, S.4
Smith, E.P.5
Barthlow, R.6
-
17
-
-
0034992131
-
Rapid differential endogenous plasminogen activator expression after acute middle cerebral artery occlusion
-
Hosomi, N., Lucero, J., Heo, J. H., Koziol, J. A., Copeland, B. R., and del Zoppo, G. J. (2001). Rapid differential endogenous plasminogen activator expression after acute middle cerebral artery occlusion. Stroke 32, 1341-1348. doi: 10.1161/01.str.32.6.1341
-
(2001)
Stroke
, vol.32
, pp. 1341-1348
-
-
Hosomi, N.1
Lucero, J.2
Heo, J.H.3
Koziol, J.A.4
Copeland, B.R.5
del Zoppo, G.J.6
-
18
-
-
42349095894
-
Thrombolytic toxicity: Blood brain barrier disruption in human ischemic stroke
-
Kidwell, C. S., Latour, L., Saver, J. L., Alger, J. R., Starkman, S., Duckwiler, G., et al. (2008). Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke. Cerebrovasc. Dis. 25, 338-343. doi: 10.1159/000118379
-
(2008)
Cerebrovasc. Dis
, vol.25
, pp. 338-343
-
-
Kidwell, C.S.1
Latour, L.2
Saver, J.L.3
Alger, J.R.4
Starkman, S.5
Duckwiler, G.6
-
19
-
-
0033597411
-
Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator
-
Kim, Y. H., Park, J. H., Hong, S. H., and Koh, J. Y. (1999). Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator. Science 284, 647-650. doi: 10.1126/science.284.5414.647
-
(1999)
Science
, vol.284
, pp. 647-650
-
-
Kim, Y.H.1
Park, J.H.2
Hong, S.H.3
Koh, J.Y.4
-
20
-
-
0033594338
-
Tissue plasminogen activator does not increase neuronal damage in rat models of global and focal ischemia
-
Klein, G. M., Li, H., Sun, P., and Buchan, A. M. (1999). Tissue plasminogen activator does not increase neuronal damage in rat models of global and focal ischemia. Neurology 52, 1381-1384. doi: 10.1212/wnl.52.7.1381
-
(1999)
Neurology
, vol.52
, pp. 1381-1384
-
-
Klein, G.M.1
Li, H.2
Sun, P.3
Buchan, A.M.4
-
21
-
-
0019860445
-
Plasminogen activator release at the neuronal growth cone
-
Krystosek, A., and Seeds, N. W. (1981). Plasminogen activator release at the neuronal growth cone. Science 213, 1532-1534. doi: 10.1126/science.7197054
-
(1981)
Science
, vol.213
, pp. 1532-1534
-
-
Krystosek, A.1
Seeds, N.W.2
-
22
-
-
84894373328
-
tPA regulates neurite outgrowth by phosphorylation of LRP5/6 in neural progenitor cells
-
Lee, S. H., Ko, H. M., Kwon, K. J., Lee, J., Han, S. H., Han, D. W., et al. (2014). tPA regulates neurite outgrowth by phosphorylation of LRP5/6 in neural progenitor cells. Mol. Neurobiol. 49, 199-215. doi: 10.1007/s12035-013-8511-x
-
(2014)
Mol. Neurobiol
, vol.49
, pp. 199-215
-
-
Lee, S.H.1
Ko, H.M.2
Kwon, K.J.3
Lee, J.4
Han, S.H.5
Han, D.W.6
-
23
-
-
0028275022
-
Localization of tissue plasminogen activator in the endothelium of a limited number of vessels
-
Levin, E. G., and del Zoppo, G. J. (1994). Localization of tissue plasminogen activator in the endothelium of a limited number of vessels. Am. J. Pathol. 144, 855-861.
-
(1994)
Am. J. Pathol
, vol.144
, pp. 855-861
-
-
Levin, E.G.1
del Zoppo, G.J.2
-
24
-
-
33646722155
-
Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator
-
Li, J., Ma, Y., Teng, Y. D., Zheng, K., Vartanian, T. K., Snyder, E. Y., et al. (2006). Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator. Proc. Natl. Acad. Sci. U S A 103, 7847-7852. doi: 10.1073/pnas.0602440103
-
(2006)
Proc. Natl. Acad. Sci. U S A
, vol.103
, pp. 7847-7852
-
-
Li, J.1
Ma, Y.2
Teng, Y.D.3
Zheng, K.4
Vartanian, T.K.5
Snyder, E.Y.6
-
25
-
-
84879526242
-
Tissue plasminogen activator regulates Purkinje neuron development and survival
-
Li, J., Yu, L., Gu, X., Ma, Y., Pasqualini, R., Arap, W., et al. (2013). Tissue plasminogen activator regulates Purkinje neuron development and survival. Proc. Natl. Acad. Sci. U S A 110, E2410-E2419. doi: 10.1073/pnas.1305010110
-
(2013)
Proc. Natl. Acad. Sci. U S A
, vol.110
, pp. E2410-E2419
-
-
Li, J.1
Yu, L.2
Gu, X.3
Ma, Y.4
Pasqualini, R.5
Arap, W.6
-
26
-
-
0037321482
-
Vampire bat salivary plasminogen activator (desmoteplase): A unique fibrinolytic enzyme that does not promote neurodegeneration
-
Liberatore, G. T., Samson, A., Bladin, C., Schleuning, W. D., and Medcalf, R. L. (2003). Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration. Stroke 34, 537-543. doi: 10.1161/01.str.0000049764.49162.76
-
(2003)
Stroke
, vol.34
, pp. 537-543
-
-
Liberatore, G.T.1
Samson, A.2
Bladin, C.3
Schleuning, W.D.4
Medcalf, R.L.5
-
27
-
-
33746933820
-
Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity
-
Liot, G., Roussel, B. D., Lebeurrier, N., Benchenane, K., Lopez-Atalaya, J. P., Vivien, D., et al. (2006). Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity. J. Neurochem. 98, 1458-1464. doi: 10.1111/j.1471-4159.2006.03982.x
-
(2006)
J. Neurochem
, vol.98
, pp. 1458-1464
-
-
Liot, G.1
Roussel, B.D.2
Lebeurrier, N.3
Benchenane, K.4
Lopez-Atalaya, J.P.5
Vivien, D.6
-
28
-
-
84855780549
-
Subacute intranasal administration of tissue plasminogen activator increases functional recovery and axonal remodeling after stroke in rats
-
Liu, Z., Li, Y., Zhang, L., Xin, H., Cui, Y., Hanson, L. R., et al. (2012). Subacute intranasal administration of tissue plasminogen activator increases functional recovery and axonal remodeling after stroke in rats. Neurobiol. Dis. 45, 804-809. doi: 10.1016/j.nbd.2011.11.004
-
(2012)
Neurobiol. Dis
, vol.45
, pp. 804-809
-
-
Liu, Z.1
Li, Y.2
Zhang, L.3
Xin, H.4
Cui, Y.5
Hanson, L.R.6
-
29
-
-
33947331063
-
NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
-
Liu, Y., Wong, T. P., Aarts, M., Rooyakkers, A., Liu, L., Lai, T. W., et al. (2007). NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J. Neurosci. 27, 2846-2857. doi: 10.1523/jneurosci.0116-07.2007
-
(2007)
J. Neurosci
, vol.27
, pp. 2846-2857
-
-
Liu, Y.1
Wong, T.P.2
Aarts, M.3
Rooyakkers, A.4
Liu, L.5
Lai, T.W.6
-
30
-
-
0038016429
-
Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin
-
Madani, R., Kozlov, S., Akhmedov, A., Cinelli, P., Kinter, J., Lipp, H. P., et al. (2003). Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin. Mol. Cell. Neurosci. 23, 473-494. doi: 10.1016/s1044-7431(03)00077-0
-
(2003)
Mol. Cell. Neurosci
, vol.23
, pp. 473-494
-
-
Madani, R.1
Kozlov, S.2
Akhmedov, A.3
Cinelli, P.4
Kinter, J.5
Lipp, H.P.6
-
31
-
-
0037391807
-
Tissue plasminogen activator and NMDA receptor cleavage
-
Matys, T., and Strickland, S. (2003). Tissue plasminogen activator and NMDA receptor cleavage. Nat. Med. 9, 371-372. doi: 10.1038/nm0403-371
-
(2003)
Nat. Med
, vol.9
, pp. 371-372
-
-
Matys, T.1
Strickland, S.2
-
32
-
-
0036458670
-
Concept of activity-induced cell death in epilepsy: Historical and contemporary perspectives
-
Meldrum, B. S. (2002). Concept of activity-induced cell death in epilepsy: historical and contemporary perspectives. Prog. Brain Res. 135, 3-11. doi: 10.1016/s0079-6123(02)35003-9
-
(2002)
Prog. Brain Res
, vol.135
, pp. 3-11
-
-
Meldrum, B.S.1
-
33
-
-
0032057384
-
Tissue plasminogen activator mediates reverse occlusion plasticity in visual cortex
-
Müller, C. M., and Griesinger, C. B. (1998). Tissue plasminogen activator mediates reverse occlusion plasticity in visual cortex.Nat. Neurosci. 1, 47-53. doi: 10.1038/248
-
(1998)
Nat. Neurosci
, vol.1
, pp. 47-53
-
-
Müller, C.M.1
Griesinger, C.B.2
-
34
-
-
0033545965
-
Role of plasminogen system components in focal cerebral ischemic infarction: A gene targeting and gene transfer study in mice
-
Nagai, N., De Mol, M., Lijnen, H. R., Carmeliet, P., and Collen, D. (1999). Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice. Circulation 99, 2440-2444. doi: 10.1161/01.cir.99.18.2440
-
(1999)
Circulation
, vol.99
, pp. 2440-2444
-
-
Nagai, N.1
De Mol, M.2
Lijnen, H.R.3
Carmeliet, P.4
Collen, D.5
-
35
-
-
0034746189
-
The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling
-
Nicole, O., Docagne, F., Ali, C., Margaill, I., Carmeliet, P., MacKenzie, E. T., et al. (2001). The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nat. Med. 7, 59-64. doi: 10.1038/83358
-
(2001)
Nat. Med
, vol.7
, pp. 59-64
-
-
Nicole, O.1
Docagne, F.2
Ali, C.3
Margaill, I.4
Carmeliet, P.5
MacKenzie, E.T.6
-
36
-
-
0023938793
-
Fibrinolysis in normal subjects-comparison between plasminogen activator inhibitor and other components of the fibrinolytic system
-
Nicoloso, G., Hauert, J., Kruithof, E. K., Van Melle, G., and Bachmann, F. (1988). Fibrinolysis in normal subjects-comparison between plasminogen activator inhibitor and other components of the fibrinolytic system. Thromb. Haemost. 59, 299-303.
-
(1988)
Thromb. Haemost
, vol.59
, pp. 299-303
-
-
Nicoloso, G.1
Hauert, J.2
Kruithof, E.K.3
Van Melle, G.4
Bachmann, F.5
-
37
-
-
0014668762
-
Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate
-
Olney, J. W. (1969). Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate. Science 164, 719-721. doi: 10.1126/science.164.3880.719
-
(1969)
Science
, vol.164
, pp. 719-721
-
-
Olney, J.W.1
-
38
-
-
0029977875
-
Neuroserpin, an axonally secreted serine protease inhibitor
-
Osterwalder, T., Contartese, J., Stoeckli, E. T., Kuhn, T. B., and Sonderegger, P. (1996). Neuroserpin, an axonally secreted serine protease inhibitor. EMBO J. 15, 2944-2953.
-
(1996)
EMBO J
, vol.15
, pp. 2944-2953
-
-
Osterwalder, T.1
Contartese, J.2
Stoeckli, E.T.3
Kuhn, T.B.4
Sonderegger, P.5
-
39
-
-
0037314824
-
Tissue plasminogen activator in the amygdala is critical for stress-induced anxiety-like behavior
-
Pawlak, R., Magarinos, A. M., Melchor, J., McEwen, B., and Strickland, S. (2003). Tissue plasminogen activator in the amygdala is critical for stress-induced anxiety-like behavior. Nat. Neurosci. 6, 168-174. doi: 10.1038/nn998
-
(2003)
Nat. Neurosci
, vol.6
, pp. 168-174
-
-
Pawlak, R.1
Magarinos, A.M.2
Melchor, J.3
McEwen, B.4
Strickland, S.5
-
40
-
-
77953244626
-
Outcome of experimental stroke in C57Bl/6 and Sv/129 mice assessed by multimodal ultra-high field MRI
-
Pham, M., Helluy, X., Braeuninger, S., Jakob, P., Stoll, G., Kleinschnitz, C., et al. (2010). Outcome of experimental stroke in C57Bl/6 and Sv/129 mice assessed by multimodal ultra-high field MRI. Exp. Transl. Stroke Med. 2:6. doi: 10.1186/2040-7378-2-6
-
(2010)
Exp. Transl. Stroke Med
, vol.2
, pp. 6
-
-
Pham, M.1
Helluy, X.2
Braeuninger, S.3
Jakob, P.4
Stoll, G.5
Kleinschnitz, C.6
-
41
-
-
34147143557
-
Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit
-
Polavarapu, R., Gongora, M. C., Yi, H., Ranganthan, S., Lawrence, D. A., Strickland, D., et al. (2007). Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit. Blood 109, 3270-3278. doi: 10.1182/blood-2006-08-043125
-
(2007)
Blood
, vol.109
, pp. 3270-3278
-
-
Polavarapu, R.1
Gongora, M.C.2
Yi, H.3
Ranganthan, S.4
Lawrence, D.A.5
Strickland, D.6
-
42
-
-
0027535364
-
Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation
-
Qian, Z., Gilbert, M. E., Colicos, M. A., Kandel, E. R., and Kuhl, D. (1993). Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 361, 453-457. doi: 10.1038/361453a0
-
(1993)
Nature
, vol.361
, pp. 453-457
-
-
Qian, Z.1
Gilbert, M.E.2
Colicos, M.A.3
Kandel, E.R.4
Kuhl, D.5
-
43
-
-
20444372592
-
Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury
-
Reddrop, C., Moldrich, R. X., Beart, P. M., Farso, M., Liberatore, G. T., Howells, D. W., et al. (2005). Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury.Stroke 36, 1241-1246. doi: 10.1161/01.str.0000166050.84056.48
-
(2005)
Stroke
, vol.36
, pp. 1241-1246
-
-
Reddrop, C.1
Moldrich, R.X.2
Beart, P.M.3
Farso, M.4
Liberatore, G.T.5
Howells, D.W.6
-
44
-
-
0020471109
-
Fibrinolytic properties of one-chain and two-chain human extrinsic (tissue-type) plasminogen activator
-
Rijken, D. C., Hoylaerts, M., and Collen, D. (1982). Fibrinolytic properties of one-chain and two-chain human extrinsic (tissue-type) plasminogen activator. J. Biol. Chem. 257, 2920-2925.
-
(1982)
J. Biol. Chem
, vol.257
, pp. 2920-2925
-
-
Rijken, D.C.1
Hoylaerts, M.2
Collen, D.3
-
45
-
-
0037088905
-
Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus
-
Salles, F. J., and Strickland, S. (2002). Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus. J. Neurosci. 22, 2125-2134.
-
(2002)
J. Neurosci
, vol.22
, pp. 2125-2134
-
-
Salles, F.J.1
Strickland, S.2
-
46
-
-
54349092419
-
Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function
-
Samson, A. L., Nevin, S. T., Croucher, D., Niego, B., Daniel, P. B., Weiss, T. W., et al. (2008). Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function. J. Neurochem. 107, 1091-1101. doi: 10.1111/j.1471-4159.2008.05687.x
-
(2008)
J. Neurochem
, vol.107
, pp. 1091-1101
-
-
Samson, A.L.1
Nevin, S.T.2
Croucher, D.3
Niego, B.4
Daniel, P.B.5
Weiss, T.W.6
-
47
-
-
0027222096
-
Extracellular proteolysis in the adult murine brain
-
Sappino, A. P., Madani, R., Huarte, J., Belin, D., Kiss, J. Z., Wohlwend, A., et al. (1993). Extracellular proteolysis in the adult murine brain. J. Clin. Invest. 92, 679-685. doi: 10.1172/jci116637
-
(1993)
J. Clin. Invest
, vol.92
, pp. 679-685
-
-
Sappino, A.P.1
Madani, R.2
Huarte, J.3
Belin, D.4
Kiss, J.Z.5
Wohlwend, A.6
-
48
-
-
0042237885
-
Absence of tissue plasminogen activator gene or activity impairs mouse cerebellar motor learning
-
Seeds, N. W., Basham, M. E., and Ferguson, J. E. (2003). Absence of tissue plasminogen activator gene or activity impairs mouse cerebellar motor learning. J. Neurosci. 23, 7368-7375.
-
(2003)
J. Neurosci
, vol.23
, pp. 7368-7375
-
-
Seeds, N.W.1
Basham, M.E.2
Ferguson, J.E.3
-
49
-
-
0033598707
-
Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene
-
Seeds, N. W., Basham, M. E., and Haffke, S. P. (1999). Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene. Proc. Natl. Acad. Sci. U S A 96, 14118-14123. doi: 10.1073/pnas.96.24.14118
-
(1999)
Proc. Natl. Acad. Sci. U S A
, vol.96
, pp. 14118-14123
-
-
Seeds, N.W.1
Basham, M.E.2
Haffke, S.P.3
-
50
-
-
0029556177
-
Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning
-
Seeds, N. W., Williams, B. L., and Bickford, P. C. (1995). Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning. Science 270, 1992-1994. doi: 10.1126/science.270.5244.1992
-
(1995)
Science
, vol.270
, pp. 1992-1994
-
-
Seeds, N.W.1
Williams, B.L.2
Bickford, P.C.3
-
51
-
-
77950572352
-
Publication bias in reports of animal stroke studies leads to major overstatement of efficacy
-
Sena, E. S., van der Worp, H. B., Bath, P. M., Howells, D. W., and Macleod, M. R. (2010). Publication bias in reports of animal stroke studies leads to major overstatement of efficacy. PLoS Biol. 8:e1000344. doi: 10.1371/journal.pbio.1000344
-
(2010)
PLoS Biol
, vol.8
-
-
Sena, E.S.1
van der Worp, H.B.2
Bath, P.M.3
Howells, D.W.4
Macleod, M.R.5
-
52
-
-
79251637340
-
Endogenous tissue plasminogen activator mediates bone marrow stromal cell-induced neurite remodeling after stroke in mice
-
Shen, L. H., Xin, H., Li, Y., Zhang, R. L., Cui, Y., Zhang, L., et al. (2011). Endogenous tissue plasminogen activator mediates bone marrow stromal cell-induced neurite remodeling after stroke in mice. Stroke 42, 459-464. doi: 10.1161/STROKEAHA.110.593863
-
(2011)
Stroke
, vol.42
, pp. 459-464
-
-
Shen, L.H.1
Xin, H.2
Li, Y.3
Zhang, R.L.4
Cui, Y.5
Zhang, L.6
-
53
-
-
72449163624
-
Hypoxia inducible factor 1 as a therapeutic target in ischemic stroke
-
Shi, H. (2009). Hypoxia inducible factor 1 as a therapeutic target in ischemic stroke. Curr. Med. Chem. 16, 4593-4600. doi: 10.2174/092986709789760779
-
(2009)
Curr. Med. Chem
, vol.16
, pp. 4593-4600
-
-
Shi, H.1
-
54
-
-
0032741931
-
Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: Studies in tPA-deficient mice and wild-type mice on a matched genetic background
-
Tabrizi, P., Wang, L., Seeds, N., McComb, J. G., Yamada, S., Griffin, J. H., et al. (1999). Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background. Arterioscler. Thromb. Vasc. Biol. 19, 2801-2806. doi: 10.1161/01.atv.19.11.2801
-
(1999)
Arterioscler. Thromb. Vasc. Biol
, vol.19
, pp. 2801-2806
-
-
Tabrizi, P.1
Wang, L.2
Seeds, N.3
McComb, J.G.4
Yamada, S.5
Griffin, J.H.6
-
55
-
-
0028783948
-
Tissue plasminogen activator for acute ischemic stroke
-
The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. (1995). Tissue plasminogen activator for acute ischemic stroke. N. Engl. J. Med. 333, 1581-1587. doi: 10.1056/NEJM199512143332401
-
(1995)
N. Engl. J. Med
, vol.333
, pp. 1581-1587
-
-
-
56
-
-
0031775308
-
Astrocyte regulation of endothelial tissue plasminogen activator in a blood-brain barrier model
-
Tran, N. D., Schreiber, S. S., and Fisher, M. (1998). Astrocyte regulation of endothelial tissue plasminogen activator in a blood-brain barrier model. J. Cereb. Blood Flow Metab. 18, 1316-1324. doi: 10.1097/00004647-199812000-00006
-
(1998)
J. Cereb. Blood Flow Metab
, vol.18
, pp. 1316-1324
-
-
Tran, N.D.1
Schreiber, S.S.2
Fisher, M.3
-
57
-
-
0029088484
-
Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator
-
Tsirka, S. E., Gualandris, A., Amaral, D. G., and Strickland, S. (1995). Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature 377, 340-344. doi: 10.1038/377340a0
-
(1995)
Nature
, vol.377
, pp. 340-344
-
-
Tsirka, S.E.1
Gualandris, A.2
Amaral, D.G.3
Strickland, S.4
-
58
-
-
0031951510
-
Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice
-
Wang, Y. F., Tsirka, S. E., Strickland, S., Stieg, P. E., Soriano, S. G., and Lipton, S. A. (1998). Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nat. Med. 4, 228-231. doi: 10.1038/nm0298-228
-
(1998)
Nat. Med
, vol.4
, pp. 228-231
-
-
Wang, Y.F.1
Tsirka, S.E.2
Strickland, S.3
Stieg, P.E.4
Soriano, S.G.5
Lipton, S.A.6
-
59
-
-
78149324499
-
Neuroserpin protects neurons from ischemia-induced plasmin-mediated cell death independently of tissue-type plasminogen activator inhibition
-
Wu, J., Echeverry, R., Guzman, J., and Yepes, M. (2010). Neuroserpin protects neurons from ischemia-induced plasmin-mediated cell death independently of tissue-type plasminogen activator inhibition. Am. J. Pathol. 177, 2576-2584. doi: 10.2353/ajpath.2010.100466
-
(2010)
Am. J. Pathol
, vol.177
, pp. 2576-2584
-
-
Wu, J.1
Echeverry, R.2
Guzman, J.3
Yepes, M.4
-
60
-
-
84870356687
-
Tissue-type plasminogen activator protects neurons from excitotoxin-induced cell death via activation of the ERK1/2-CREB-ATF3 signaling pathway
-
Wu, F., Echeverry, R., Wu, J., An, J., Haile, W. B., Cooper, D. S., et al. (2013). Tissue-type plasminogen activator protects neurons from excitotoxin-induced cell death via activation of the ERK1/2-CREB-ATF3 signaling pathway. Mol. Cell. Neurosci.52, 9-19. doi: 10.1016/j.mcn.2012.10.001
-
(2013)
Mol. Cell. Neurosci
, vol.52
, pp. 9-19
-
-
Wu, F.1
Echeverry, R.2
Wu, J.3
An, J.4
Haile, W.B.5
Cooper, D.S.6
-
61
-
-
84863935926
-
Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain
-
Wu, F., Wu, J., Nicholson, A. D., Echeverry, R., Haile, W. B., Catano, M., et al. (2012). Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain. J. Neurosci. 32, 9848-9858. doi: 10.1523/jneurosci.1241-12.2012
-
(2012)
J. Neurosci
, vol.32
, pp. 9848-9858
-
-
Wu, F.1
Wu, J.2
Nicholson, A.D.3
Echeverry, R.4
Haile, W.B.5
Catano, M.6
-
62
-
-
1642336131
-
Neuroserpin: A selective inhibitor of tissue-type plasminogen activator in the central nervous system
-
Yepes, M., and Lawrence, D. A. (2004). Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system. Thromb. Haemost. 91, 457-464. doi: 10.1160/th03-12-0766
-
(2004)
Thromb. Haemost
, vol.91
, pp. 457-464
-
-
Yepes, M.1
Lawrence, D.A.2
-
63
-
-
0036084622
-
Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent
-
Yepes, M., Sandkvist, M., Coleman, T. A., Moore, E., Wu, J. Y., Mitola, D., et al. (2002). Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent. J. Clin. Invest. 109, 1571-1578. doi: 10.1172/jci200214308
-
(2002)
J. Clin. Invest
, vol.109
, pp. 1571-1578
-
-
Yepes, M.1
Sandkvist, M.2
Coleman, T.A.3
Moore, E.4
Wu, J.Y.5
Mitola, D.6
-
64
-
-
0345824713
-
Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein
-
Yepes, M., Sandkvist, M., Moore, E. G., Bugge, T. H., Strickland, D. K., and Lawrence, D. A. (2003). Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. J. Clin. Invest. 112, 1533-1540. doi: 10.1172/jci19212
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1533-1540
-
-
Yepes, M.1
Sandkvist, M.2
Moore, E.G.3
Bugge, T.H.4
Strickland, D.K.5
Lawrence, D.A.6
-
65
-
-
0034661923
-
Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis
-
Yepes, M., Sandkvist, M., Wong, M. K., Coleman, T. A., Smith, E., Cohan, S. L., et al. (2000). Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis. Blood 96, 569-576.
-
(2000)
Blood
, vol.96
, pp. 569-576
-
-
Yepes, M.1
Sandkvist, M.2
Wong, M.K.3
Coleman, T.A.4
Smith, E.5
Cohan, S.L.6
-
66
-
-
67649752347
-
The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors
-
Yuan, H., Vance, K. M., Junge, C. E., Geballe, M. T., Snyder, J. P., Hepler, J. R., et al. (2009). The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors. J. Biol. Chem. 284, 12862-12873. doi: 10.1074/jbc.M805123200
-
(2009)
J. Biol. Chem
, vol.284
, pp. 12862-12873
-
-
Yuan, H.1
Vance, K.M.2
Junge, C.E.3
Geballe, M.T.4
Snyder, J.P.5
Hepler, J.R.6
-
67
-
-
20044374010
-
Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia
-
Zhang, S., Boyd, J., Delaney, K., and Murphy, T. H. (2005). Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia. J. Neurosci. 25, 5333-5338. doi: 10.1523/jneurosci.1085-05.2005
-
(2005)
J. Neurosci
, vol.25
, pp. 5333-5338
-
-
Zhang, S.1
Boyd, J.2
Delaney, K.3
Murphy, T.H.4
-
68
-
-
35348892539
-
Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation
-
Zhang, X., Polavarapu, R., She, H., Mao, Z., and Yepes, M. (2007). Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation. Am. J. Pathol. 171, 1281-1290. doi: 10.2353/ajpath.2007.070472
-
(2007)
Am. J. Pathol
, vol.171
, pp. 1281-1290
-
-
Zhang, X.1
Polavarapu, R.2
She, H.3
Mao, Z.4
Yepes, M.5
|