Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival

Journal of Biological Chemistry

Volumn 272, Issue 52, 1997, Pages 33062-33067

  Hastings, Gregg A ^a,c   Coleman, Timothy A ^a   Haudenschild, Christian C ^b   Stefansson, Steingrimur ^b   Smith, Elizabeth P ^b   Barthlow, Ray ^a   Cherry, Scott ^a   Sandkvist, Maria ^b   Lawrence, Daniel A ^b  

^a GLAXOSMITHKLINE   (United States)

^b HOLLAND LABORATORY   (United States)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NERVE GROWTH FACTOR; NEUROSERPIN; PLASMIN; PLASMINOGEN ACTIVATOR; SERINE PROTEINASE INHIBITOR; THROMBIN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ARTICLE; BRAIN; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CHOROID PLEXUS; EPENDYMA CELL; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MOTOR ACTIVITY; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PURKINJE CELL; SPINAL CORD;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CELL SURVIVAL; GLYCOPROTEINS; HUMANS; IMMUNOENZYME TECHNIQUES; KINETICS; MICE; NEURONS; NEUROPEPTIDES; RNA, MESSENGER; SERINE PROTEINASE INHIBITORS; SERPINS; SPODOPTERA; TISSUE DISTRIBUTION; TISSUE PLASMINOGEN ACTIVATOR;

INSECTA;

EID: 0031452755     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.52.33062     Document Type: Article

References (32)

1. Osterwalder, T., Contartese, J., Stoeckli, E. T., Kuhn, T. B., and Sonderegger, P. (1996) EMBO J. 15, 2944-2953
2. Schrimpf, S. P., Bleiker, A. J., Brecevic, L., Kozlov, S. V., Berger, P., Osterwalder, T., Krueger, S. R., Schinzel, A., and Sonderegger, P. (1997) Genomics 40, 55-62
3. Carroll, P. M., Tsirka, S. E., Richards, W. G., Frohman, M. A., and Strickland, S. (1994) Development 120, 3173-3183
4. Friedman, G. C., and Seeds, N. W. (1995) J. Comp. Neurol. 360, 658-670
5. Friedman, G. C., and Seeds, N. W. (1994) Brain Res. Dev. Brain Res. 81, 41-49
6. Padro, T., van den Hoogen, C. M., and Emeis, J. J. (1990) Blood Coagul. Fibrinolysis 1, 601-608
7. Sappino, A. P., Madani, R., Huarte, J., Belin, D., Kiss, J. Z., Wohlwend, A., and Vassalli, J. D. (1993) J. Clin. Invest. 92, 679-685
8. Ware, J. H., Dibenedetto, A. J., and Pittman, R. N. (1995) Brain Res. Bull. 37, 275-281
9. Seeds, N. W., Williams, B. L., and Bickford, P. C. (1995) Science 270, 1992-1994
10. Qian, Z., Gilbert, M. E., Colicos, M. A., Kandel, E. R., and Kuhl, D. (1993) Nature 361, 453-457
11. Tsirka, S. E., Gualandris, A., Amaral, D. G., and Strickland, S. (1995) Nature 377, 340-344
12. Tsirka, S. E., Rogove, A. D., and Strickland, S. (1996) Nature 384, 123-124
13. Tsirka, S. E., Rogove, A. D., Bugge, T. H., Degen, J. L., and Strickland, S. (1997) J. Neurosci. 17, 543-552
14. Sherman, P. M., Lawrence, D. A., Yang, A. Y., Vandenberg, E. T., Paielli, D., Olson, S. T., Shore, J. D., and Ginsburg, D. (1992) J. Biol. Chem. 267, 7588-7595
15. Coleman, T. A., Huddleston, K. A., Ruben, S. M., Rosen, C. A., and Gentz, R. (1997) Protein Expression Purif. 9, 40-48
16. Kitz, R., and Wilson, I. B. (1962) J Biol. Chem. 237, 3245-3249
17. Olson, S. T., Bock, P. E., Kvassman, J., Shore, J. D., Lawrence, D. A., Ginsburg, D., and Björk, I. (1995) J Biol. Chem. 270, 30007-30017
18. Gettins, P. G. W., Patston, P. A., and Olson, S. T. (1996) in Serpins: Structure, Function and Biology (Gettins, P. G. W., Patston, P. A., and Olson, S. T., eds) pp. 33-63, R. G. Landes Company, Austin, TX
19. Lawrence, D. A., Ginsburg, D., Day, D. E., Berkenpas, M. B., Verhamme, I. M., Kvassman, J.-O., and Shore, J. D. (1995) J Biol. Chem. 270, 25309-25312
20. Wilczynska, M., Fa, M., Ohlsson, P.-I., and Ny, T. (1995) J. Biol. Chem. 270, 29652-29655
21. Lawrence, D. A. (1997) Nat. Struct. Biol. 4, 339-341
22. Shore, J. D., Day, D. E., Francis-Chmura, A. M., Verhamme, I., Kvassman, J., Lawrence, D. A., and Ginsburg, D. (1994) J. Biol. Chem. 270, 5395-5398
23. Gettins, P. G. W., Patston, P. A., and Olson, S. T. (1996) in Serpins: Structure, Function and Biology (Gettins, P. G. W., Patston, P. A., and Olson, S. T., eds) pp. 65-109, R. G. Landes Company, Austin, TX
24. Stratikos, E., and Gettins, P. G. W. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 453-458
25. Wilczynska, M., Fa, M., Karolin, J., Ohlsson, P.-I., Johansson, L. B.-Å., and Ny, T. (1997) Nat. Struct. Biol. 4, 354-357
26. Parmer, R. J., Mahata, M., Mahata, S., Sebald, M. T., O'Connor, D. T., and Miles, L. A. (1997) J. Biol. Chem. 272, 1976-1982
27. Lawrence, D. A., and Ginsburg, D. (1995) in Molecular Basis of Thrombosis and Hemostasis (High, K. A., and Roberts, H. R., eds) pp. 517-543, Marcel Dekker, Inc., New York
28. Keijer, J., Linders, M., Wegman, J. J., Ehrlich, H. J., Mertens, K., and Pannekoek, H. (1991) Blood 78, 1254-1261
29. Scott, R. W., Bergman, B. L., Bajpai, A., Hersh, R. T., Rodriguez, H., Jones, B. N., Barreda, C., Watts, S., and Baker, J. B. (1985) J. Biol. Chem. 260, 7029-7034
30. Sawdey, M. S., and Loskutoff, D. J. (1991) J. Clin. Invest. 88, 1346-1353
31. Mansuy, I. M., van der Putten, H., Schmid, P., Meins, M., Botteri, F. M., and Monard, D. (1993) Development 119, 1119-1134
32. Gualandris, A., Jones, T. E., Strickland, S., and Tsirka, S. E. (1996) J. Neurosci. 16, 2220-2225