Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait

Experimental Neurology

Volumn 249, Issue , 2013, Pages 8-19

  Cops, Elisa J ^a   Sashindranath, Maithili ^a   Daglas, Maria ^a   Short, Kieran M ^a   da Fonseca Pereira, Candida ^a,c   Pang, Terence Y ^b   Lijnen, Roger H ^d   Smyth, Ian M ^a   Hannan, Anthony J ^b   Samson, Andre L ^a   Medcalf, Robert L ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c BURNET INSTITUTE   (Australia)

^d UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Astrogliosis; Ataxia; Calbindin; Cerebellum; DigiGait; Huntington's disease; Neurodegeneration; Plasminogen activation; Purkinje neuron; Tissue type plasminogen activator

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; ATAXIA; ATROPHY; CELL DENSITY; CELL LOSS; CEREBELLUM DISEASE; CEREBELLUM INJURY; CONTROLLED STUDY; DEGENERATIVE DISEASE; DENDRITE; ENZYME ACTIVITY; GAIT DISORDER; GENE; GENE EXPRESSION; INTERNEURON; MALE; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOUSE; MOUSE STRAIN; NERVE CELL DEGENERATION; NERVE CELL LESION; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PROMOTER REGION; PURKINJE CELL; THY1.2 GENE; TRANSGENIC MOUSE;

(HD); (OPT); (SCA); (TPA); ASTROGLIOSIS; ATAXIA; CALBINDIN; CEREBELLUM; DIGIGAIT; HUNTINGTON'S DISEASE; NEURODEGENERATION; OPTICAL PROJECTION TOMOGRAPHY; PLASMINOGEN ACTIVATION; PURKINJE NEURON; SPINOCEREBELLAR ATAXIA; TISSUE-TYPE PLASMINOGEN ACTIVATOR;

ANIMALS; ATAXIA; EXTRACELLULAR FLUID; GAIT; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PURKINJE CELLS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84883405401     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.08.001     Document Type: Article

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