Reshaping of human macrophage polarization through modulation of glucose catabolic pathways

Journal of Immunology

Volumn 195, Issue 5, 2015, Pages 2442-2451

  Izquierdo, Elena ^a   Cuevas, Víctor Delgado ^a   Fernández Arroyo, Salvador ^b,c   Riera Borrull, Marta ^b,c   Orta Zavalza, Emmanuel ^a   Joven, Jorge ^b,c   Rial, Eduardo ^a   Corbi, Angel L ^a   Escribese, María M ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b HOSPITAL UNIVERSITARI SANT JOAN DE REUS   (Spain)

^c Campus of International Excellence Southern Catalonia   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOSE; GLUCOSE TRANSPORTER 1; GLYCOLYTIC ENZYME; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; MACROPHAGE ELASTASE; MESSENGER RNA; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; TUMOR NECROSIS FACTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; COLONY STIMULATING FACTOR 1; CYTOKINE; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF1A PROTEIN, HUMAN; TRANSCRIPTOME;

AEROBIC METABOLISM; ANAEROBIC GLYCOLYSIS; ARTICLE; CONTROLLED STUDY; CXCL10 GENE; EGLN3 GENE; EXTRACELLULAR ACIDIFICATION RATE; FBP1 GENE; GENE; GENE EXPRESSION REGULATION; GENE SWITCHING; GLYCOLYSIS; HIF 1ALPHA GENE; HIF 2ALPHA GENE; HK3 GENE; HUMAN; HUMAN CELL; IL1B GENE; IL23 GENE; IL6 GENE; IMMUNOMODULATION; INHBA GENE; LDHA GENE; MACROPHAGE ACTIVATION; METABOLIC CAPACITY; METABOLIC PARAMETERS; MITOCHONDRIAL RESPIRATION; MMP12 GENE; OXYGEN CONSUMPTION; OXYGEN TENSION; PDK1 GENE; PFKFB2 GENE; PFKFB3 GENE; PFKP GENE; PKM2 GENE; PRIORITY JOURNAL; SERPINE1 GENE; SLC2A1 GENE; TNF GENE; TRANSCRIPTOMICS; UPREGULATION; CELL CULTURE; CELL HYPOXIA; DNA MICROARRAY; DRUG EFFECTS; ENERGY METABOLISM; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, WESTERN; CELL HYPOXIA; CELLS, CULTURED; CYTOKINES; ENERGY METABOLISM; GLUCOSE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MACROPHAGE ACTIVATION; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTOME;

EID: 84940121426     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1403045     Document Type: Article

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