Direct Type I IFN but Not MDA5/TLR3 Activation of Dendritic Cells Is Required for Maturation and Metabolic Shift to Glycolysis after Poly IC Stimulation

PLoS Biology

Volumn 12, Issue 1, 2014, Pages

  Pantel, Austin ^a   Teixeira, Angela ^a   Haddad, Elias ^b   Wood, Elizabeth G ^c   Steinman, Ralph M ^a   Longhi, M Paula ^a,c  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Vaccine and Gene Therapy Institute of Florida   (United States)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; ANIMALS; ANTIGEN PRESENTATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DEAD-BOX RNA HELICASES; DENDRITIC CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLYCOLYSIS; IMMUNITY, INNATE; INJECTIONS, INTRAPERITONEAL; INTERFERON-ALPHA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OXIDATIVE PHOSPHORYLATION; POLY I-C; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3; TRANSCRIPTION, GENETIC;

EID: 84893804974     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001759     Document Type: Article

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