Activated Macrophages as a Novel Determinant of Tumor Cell Radioresponse: The Role of Nitric Oxide-Mediated Inhibition of Cellular Respiration and Oxygen Sparing

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 5, 2010, Pages 1520-1527

  Jiang, Heng ^a   De Ridder, Mark ^a,b   Verovski, Valeri N ^b   Sonveaux, Pierre ^c   Jordan, Bénédicte F ^c   Law, Kalun ^a   Monsaert, Christinne ^a   Van den Berge, Dirk L ^b   Verellen, Dirk ^b   Feron, Olivier ^c   Gallez, Bernard ^c   Storme, Guy A ^a,b  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED MACROPHAGES; CELLULAR RESPIRATION; CLONOGENIC ASSAYS; ELECTRON PARAMAGNETIC RESONANCE; ENZYMATIC ACTIVITIES; HEME OXYGENASE-1; INDUCIBLE NITRIC OXIDE SYNTHASE (INOS); LIPOPOLYSACCHARIDES; METABOLIC OXYGEN CONSUMPTION; OXYGEN CONSUMPTION; RADIO-SENSITIZATION; RESPIRATORY ACTIVITY; REVERSE TRANSCRIPTION-POLYMERASE CHAIN REACTION; TUMOR CELLS; TUMOR MICROENVIRONMENT; WESTERN BLOTTING;

CARBON MONOXIDE; MACROPHAGES; METABOLISM; NITRIC OXIDE; OXYGEN; PARAMAGNETIC RESONANCE; POLYMERASE CHAIN REACTION; PORPHYRINS;

TUMORS;

AMINOGUANIDINE; BACTERIUM LIPOPOLYSACCHARIDE; BILIRUBIN; CARBON MONOXIDE; GAMMA INTERFERON; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRITE; OXYGEN;

ANIMAL CELL; ARTICLE; BYSTANDER EFFECT; CELL ACTIVATION; CELL ADHESION; CELL HYPOXIA; CELL RESPIRATION; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ELECTRODE; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; GENE EXPRESSION; HOMEOSTASIS; MACROPHAGE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSLATION INITIATION; TUMOR CELL; WESTERN BLOTTING;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; CELL RESPIRATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME ACTIVATION; GUANIDINES; HEME OXYGENASE-1; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXYGEN CONSUMPTION; RADIATION TOLERANCE;

EID: 77949549515     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.10.047     Document Type: Article

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