Microfluidic Assembly of a Multifunctional Tailorable Composite System Designed for Site Specific Combined Oral Delivery of Peptide Drugs

ACS Nano

Volumn 9, Issue 8, 2015, Pages 8291-8302

  Araújo, Francisca ^a,b,c,d   Shrestha, Neha ^a   Shahbazi, Mohammad Ali ^a   Liu, Dongfei ^a   Herranz Blanco, Bárbara ^a   Mäkilä, Ermei M ^a,e   Salonen, Jarno J ^e   Hirvonen, Jouni T ^a   Granja, Pedro L ^b,c,d   Sarmento, Bruno ^b,c,f   Santos, Hélder A ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF PORTO   (Portugal)

^c INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

^d UNIVERSITY OF PORTO   (Portugal)

^e UNIVERSITY OF TURKU   (Finland)

^f INSTITUTO DE INVESTIGAÇÃO E FORMAÇÃO AVANÇADA EM CIÊNCIAS E TECNOLOGIAS DA SAÚDE   (Portugal)

Author keywords

chitosan; dual delivery; microfluidics; PLGA; porous silicon

Indexed keywords

BIOCHEMISTRY; CHITIN; CHITOSAN; NANOPARTICLES; PEPTIDES; POLYMERS; POROUS SILICON;

CELL-PENETRATING PEPTIDE; DUAL-DELIVERY; GLUCAGON-LIKE PEPTIDE-1; HYDROXYPROPYL METHYLCELLULOSE; MULTIFUNCTIONAL SYSTEMS; PLGA; POLY LACTIDE-CO-GLYCOLIDE; TYPE 2 DIABETES MELLITUS;

MICROFLUIDICS;

CELL PENETRATING PEPTIDE; CHITOSAN; DIPEPTIDYL PEPTIDASE IV; DPP4 PROTEIN, HUMAN; GLUCAGON LIKE PEPTIDE 1; HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; METHYLCELLULOSE; NANOPARTICLE; POLYGLACTIN; SILICON;

ANALOGS AND DERIVATIVES; CACO 2 CELL LINE; CELL SURVIVAL; CHEMISTRY; COCULTURE; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG FORMULATION; DRUG POTENTIATION; DRUG RELEASE; HT 29 CELL LINE; HUMAN; KINETICS; METABOLISM; MICROFLUIDICS; PERMEABILITY; PH; POROSITY; PROCEDURES; ULTRASTRUCTURE;

CACO-2 CELLS; CELL SURVIVAL; CELL-PENETRATING PEPTIDES; CHITOSAN; COCULTURE TECHNIQUES; DIPEPTIDYL PEPTIDASE 4; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; DRUG SYNERGISM; GLUCAGON-LIKE PEPTIDE 1; HT29 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; METHYLCELLULOSE; MICROFLUIDICS; NANOPARTICLES; PERMEABILITY; POLYGLACTIN 910; POROSITY; SILICON;

EID: 84940121374     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b02762     Document Type: Article

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