An MRI Method to Map Tumor Hypoxia Using Red Blood Cells Loaded with a pO2-Responsive Gd-Agent

ACS Nano

Volumn 9, Issue 8, 2015, Pages 8239-8248

  Di Gregorio, Enza ^a   Ferrauto, Giuseppe ^a   Gianolio, Eliana ^a   Lanzardo, Stefania ^a   Carrera, Carla ^a   Fedeli, Franco ^a   Aime, Silvio ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

contrast agents; Gd DOTP; magnetic resonance imaging; red blood cells; tumor hypoxia; vascular volume

Indexed keywords

BLOOD; CELLS; OXYGENATION; PROBES; TUMORS;

CONTRAST AGENT; PHOTO-ACOUSTIC IMAGING; RED BLOOD CELL; SEPARATE EFFECTS; SPATIAL AND TEMPORAL RESOLUTIONS; TUMOR HYPOXIA; VASCULAR OXYGENATION; VASCULAR VOLUME;

MAGNETIC RESONANCE IMAGING;

CONTRAST MEDIUM; GADOLINIUM; GADOLINIUM-1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAKIS(METHYLENEPHOSPHONIC ACID); GADOTERIDOL; HETEROCYCLIC COMPOUND; ORGANOMETALLIC COMPOUND; ORGANOPHOSPHORUS COMPOUND; OXYGEN;

ALLOTRANSPLANTATION; ANIMAL; ANOXIA; BAGG ALBINO MOUSE; BLOOD; CANCER STAGING; CANCER TRANSPLANTATION; CHEMISTRY; ERYTHROCYTE; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; MAMMARY NEOPLASMS, ANIMAL; METABOLISM; MOUSE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHOTOACOUSTICS; PROCEDURES; STAINING; VASCULARIZATION;

ANIMALS; ANOXIA; CONTRAST MEDIA; ERYTHROCYTES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GADOLINIUM; HETEROCYCLIC COMPOUNDS; HUMANS; MAGNETIC RESONANCE IMAGING; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, INBRED BALB C; NEOPLASM STAGING; NEOPLASM TRANSPLANTATION; ORGANOMETALLIC COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; OXYGEN; PHOTOACOUSTIC TECHNIQUES; STAINING AND LABELING; TRANSPLANTATION, HOMOLOGOUS;

EID: 84940121373     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b02604     Document Type: Article

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